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The map label for this gene is luxQ [H]

Identifier: 150003414

GI number: 150003414

Start: 1134080

End: 1138120

Strand: Reverse

Name: luxQ [H]

Synonym: BVU_0839

Alternate gene names: 150003414

Gene position: 1138120-1134080 (Counterclockwise)

Preceding gene: 150003420

Following gene: 150003413

Centisome position: 22.04

GC content: 40.39

Gene sequence:

>4041_bases
ATGAGAAAGATATTCGTACTTTGGCTCTTGCTGCTGTCGGTTGTTTCATTGGCACAACCTTATTCTGTTAAGCAGCTTGG
TATAGAGAAGGGATTATCCAATAATTATGTGGTGAGCATTGCTCAAGACAAACAGGGCTTTCTGTGGTTTGCCACGGAGG
AAGGGTTGAACAAATTCGATGGTACCCGTTTCATTACTTATTTGAAGAATGAAGATTTGACAAGGCAGGGTATAACAGGC
AATGAACTGAATTGTTTGTTGGATGATCCTCAGGATTCTATCCTTTGGATAGGCACGCAAAGGGCCGGTCTGAATGCGTA
TGACTATGTAAATAACACTTTTCTTTGCTATAGGCATGATGGCGAGAACCCCGAAAGTCTGATAACGGATGATGTTACTA
AGATTGTGGCAGCTACAGATGGTAATCTTTGGATTACGACATATTGGCGGGGAGTAGATTATTTCGATAAAAAGGCTGGA
AAATTCATTCATTACAATACTCAAACAGTTCCGGGATTGGCTAGCGATAATATTTGGTCGGTTGTTGATGGAGGAGATGG
AAAGTTGTATATGGGGCATGTGCATCATGGATTCAGTGTGTTGTCTCTTAAAGATAAAAAAGTAAAGAACTTTATGCATG
ACCCTGAAGATCCGGTCAGTTTGCCAGGTAATGGGGTAACTTGCATTTATAAGGACTTAAGCGGTAATATTTGGCTGGGA
ACAGACCGGGGGCTGGCACTGTTCAATCCGGAAGCCGAAAATTTTATCCATTTTCATCATAGTGAGGACGGGGTTCCTCA
TACCGTATTTGATATCAGACAATTTGATGGGAATAAACTTTGGATTGCCATGGAATTTGGAGGAATAGCCATTTTGGATT
TAACGCAACGTATGTTTCTTTCTCCTGACCAAGTGCGTTTTCAATATATAAAGGAAGGGGATGATGAATACAGTCTCTCT
AATTCTACTGTACGTTGTTTGTTTCAGGACTCCTTTAAAAATGTATGGGCTGGTATGTGGGGAGGTGGAATTAATTTTCT
TAGCCATGAATCTTCCTATTTTAATGTTTATAGTTATTCTCCTATCCAGCATTCGGGTAGTAGCCTGAATAATAAGACAG
CAAGTAGTGTATGCGTAGCAAGGGATGGAAAGTTATGGATCGGAACCGATGGGGGAGGCATCAATGTATTTGATAAAGGC
AAGCGGGTGGCGGTTTATAAAGAAGAAACCGGTGATTTGACTGATAATTCCATACAGGCTGCACTTTGTGATTCGGAAGG
AAACCTTTGGTTTGGATCGTTTATGGGAGGAGTGGATTTTTATGATGTGAAAAAGAAAAGTTTTCACCAGATTTTTCCTA
AAGATAAAACAGGGGAAGATGTGCGTGCACTATATGAAGATGCAGAATATGTATGGATAGGAACTAGTAATGGCATCTAT
AAGGTACGCTTGCATGATAAAGGCATTGCAGATCATTATACAGTAGAGAATAATCTGGTGAGATGTATCTCGAAAGATAA
TCTTAATCGTTTATGGATTGGTACTTTCGGAGGAGGATTAGGGGTTTTTGATGAACATTTTCAGTGCGTTAAACTTTTTA
ACGTGACTTCTCTTTTTCCCTCTAATACTATCAATACTGTTTATATGGATAGTCAGAACAGAATGTGGATAGGAACGGGA
GAAGGTCTGGTTTGTTTTCCATCCTCTCAGAGTTGGGACTATAAAGTATATCGCAGTGAGGAGGGTTTGTCCAATGTCCA
TATACGTGCCATTACGGAAGATAATCATGGAAATATATGGGTGAGCACCAATAAAGGTATCAGCTGCTTGTTGAAAGACA
AGGAGGTTTTCTATAATTACGATCATTGGGATAATGTGCCTATGGGCAATTTCATGAGTGGAAGTGTGGCGGAAGCTAAG
GATGGAACACTTTATTTTGGCTCAATCAATGGCTTATGCCGTTTTAATCCAGATCAGGTATTGGAAAAACGAGAGTCACC
TGCTGCAATTATTACGGAGATGCGTATATTCGGCCCGTTGCGTGATACGGACAGTAATGAAAAGGTGATGGCGCTTGAAG
GCCAGTCGGAAGTACGTTTAAGCTATATGCAAAATAACTTCAGCGTCACCTTCAATATACAGAATTATGCCTTGGCCGAT
CAAGTGGAATATGCTTATATGTTGAAAGGGTTGGAAAATTCATGGTATACAGTAACCGATCCTAATAATGTGACTTTCCG
TAATATACCTCCGGGAAATTATTGTTTTCAGGTAAAGACAAGAATACGGAATCAGGAATGGGCGGATGAGATAGCTTCTC
TGGATATCCGTATTGACCCGCCTGTATGGCTTACGTGGTGGGCCAAGTTATTTTATATTCTTTCGGGTGTTTCTGTCCTG
TATTTTATTCTTCATGCCTATAAAAAGAAACTGGATATGGAGTCTCTCTATGAGTTGGAGAAGAAAAATCATGAGCAGGA
ACAGGAACTGAATAATGAGCGTTTACGTTTCTATACCAATATCACACATGAGTTGCGTACCCCTTTGACGTTGATTCTGG
GACCGTTGGAAGATATGCAGAAAAGTAATTCTTTATCAGGGAAAGATTCACAGAAAATATCGGTTATCCATCAAAGCGCC
ATCCGGTTGTTGAACCTGATTAATCAGATACTGGAGTTCAGAAAAACGGAAACCCAAAACAAGAAATTATGTGTAAGTCG
TGACAATCTGGCAGCCCTTGTACACGAGATCGGACTGAAGTATAAGGAATTGAACCGGAAACCTGAGATTGATTTCTGTC
TTGAGATTGAGCAGGAAGATATGTCTTTGTTTTTTGATAAGGAGGTAGTAACGATTATGCTGGATAATTTGATCTCCAAT
GCTATAAAATATACAGAGAAAGGAACTATAACTTTAGGATTACATCAGGTGGTCCGGAATAATATACACCATACGGAAAT
CAGTGTGAGTGACACCGGTTTCGGTATTGCTCCCGATGCATTGCCTCATATTTTTGACCGTTATTATCAAGAGGGAAGCG
AACATCAGGCTTCAGGAACAGGTATTGGTCTGGCTCTGGTAAAGAACCTGGTAGTTTTGCATGAGGGGGAGATCAGGGTT
GAAAGTTCTTTGAATGTGGGAAGTACTTTTTATGTCAGTCTGCTGACGGATAACACGTATCCCCATGTGCTGCATGCTGA
CTCGACGGAGAAAACTTCCGATGAAAAGGACGAAAAAGAAGAAAATATAGAACCTGTGCATAGTGGTAAGCGTATTCTGC
TGATAGTGGAAGATAATAGGGACATCTGTGATTATATTGTAGAATCTTTCTCGGACGATTTTGAAGTGAGGACTGCCGCC
AATGGTGAACAAGGTTTGGAACAAGCATTGGGCTGCATTCCTGATATTATAGTCAGTGATATCATGATGCCGGTGATGAA
CGGCATTGTGATGTGCCGGAAATTGAAAGAAGACTTGCGTACCAGCCATATTCCCATTATTTTGCTGACGGCAAAGGATT
CTTTGCAAGATAAGGAAGAAGGGTATCAAGTGGGTGCTGACTCTTATCTGACAAAGCCTTTCAGTGCTACTTTGTTGCAT
AGCCGTATCCATAATTTGCTTGAATCCCGCAAGTTGTTGGCAGAGCGTTTTAATACGAATTCCATACTCATTGACAAACG
TGCGGCAGTAACCGAGTCTATGAATAAATTGGATAATGAGTTCCTTGAGAAGATTAACAAGCTGATTGAAGATCGTCTTT
CTTCTGAGAAAATTGATATCGGTTATTTGTCGGACGCCATGTGTATGAGTAATTCTACCCTATATCGGAAGATGAAGGCA
TTGACCGGACTTTCCACCAATGAATATATCCGCAAAATAAAGATGCAATATGCGGAACGTTTGTTATTAGAGGGGAAATA
CAATATTTCAGAAGTTGCGTTCAAGGTGGGAATTAACAGTACGGTCTATTTTCGTCAGTGTTTTAAAGATGAATTCGGTA
TGGCTCCTTCTGATTATCTGAAAAAGATAAAACCGGAATAG

Upstream 100 bases:

>100_bases
AAAAGGGAGGTAAATCTTGCAATGCATGATTATGTATCTAAAATACAGACTTTATTTGTATTTTTGAACCATATTATTTA
ACAATGTGTACACTGATGCT

Downstream 100 bases:

>100_bases
AGTGGTTGTGTAAGCTGTTTCTTCCATATAGTTAAGCCTTTTTTTACAGTCATCTGCTACAGTCTCCGCCAGTGGACTGT
AAGGTCTGCTTGGGTGGACT

Product: two-component system sensor histidine kinase/response regulator, hybrid

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1346; Mature: 1346

Protein sequence:

>1346_residues
MRKIFVLWLLLLSVVSLAQPYSVKQLGIEKGLSNNYVVSIAQDKQGFLWFATEEGLNKFDGTRFITYLKNEDLTRQGITG
NELNCLLDDPQDSILWIGTQRAGLNAYDYVNNTFLCYRHDGENPESLITDDVTKIVAATDGNLWITTYWRGVDYFDKKAG
KFIHYNTQTVPGLASDNIWSVVDGGDGKLYMGHVHHGFSVLSLKDKKVKNFMHDPEDPVSLPGNGVTCIYKDLSGNIWLG
TDRGLALFNPEAENFIHFHHSEDGVPHTVFDIRQFDGNKLWIAMEFGGIAILDLTQRMFLSPDQVRFQYIKEGDDEYSLS
NSTVRCLFQDSFKNVWAGMWGGGINFLSHESSYFNVYSYSPIQHSGSSLNNKTASSVCVARDGKLWIGTDGGGINVFDKG
KRVAVYKEETGDLTDNSIQAALCDSEGNLWFGSFMGGVDFYDVKKKSFHQIFPKDKTGEDVRALYEDAEYVWIGTSNGIY
KVRLHDKGIADHYTVENNLVRCISKDNLNRLWIGTFGGGLGVFDEHFQCVKLFNVTSLFPSNTINTVYMDSQNRMWIGTG
EGLVCFPSSQSWDYKVYRSEEGLSNVHIRAITEDNHGNIWVSTNKGISCLLKDKEVFYNYDHWDNVPMGNFMSGSVAEAK
DGTLYFGSINGLCRFNPDQVLEKRESPAAIITEMRIFGPLRDTDSNEKVMALEGQSEVRLSYMQNNFSVTFNIQNYALAD
QVEYAYMLKGLENSWYTVTDPNNVTFRNIPPGNYCFQVKTRIRNQEWADEIASLDIRIDPPVWLTWWAKLFYILSGVSVL
YFILHAYKKKLDMESLYELEKKNHEQEQELNNERLRFYTNITHELRTPLTLILGPLEDMQKSNSLSGKDSQKISVIHQSA
IRLLNLINQILEFRKTETQNKKLCVSRDNLAALVHEIGLKYKELNRKPEIDFCLEIEQEDMSLFFDKEVVTIMLDNLISN
AIKYTEKGTITLGLHQVVRNNIHHTEISVSDTGFGIAPDALPHIFDRYYQEGSEHQASGTGIGLALVKNLVVLHEGEIRV
ESSLNVGSTFYVSLLTDNTYPHVLHADSTEKTSDEKDEKEENIEPVHSGKRILLIVEDNRDICDYIVESFSDDFEVRTAA
NGEQGLEQALGCIPDIIVSDIMMPVMNGIVMCRKLKEDLRTSHIPIILLTAKDSLQDKEEGYQVGADSYLTKPFSATLLH
SRIHNLLESRKLLAERFNTNSILIDKRAAVTESMNKLDNEFLEKINKLIEDRLSSEKIDIGYLSDAMCMSNSTLYRKMKA
LTGLSTNEYIRKIKMQYAERLLLEGKYNISEVAFKVGINSTVYFRQCFKDEFGMAPSDYLKKIKPE

Sequences:

>Translated_1346_residues
MRKIFVLWLLLLSVVSLAQPYSVKQLGIEKGLSNNYVVSIAQDKQGFLWFATEEGLNKFDGTRFITYLKNEDLTRQGITG
NELNCLLDDPQDSILWIGTQRAGLNAYDYVNNTFLCYRHDGENPESLITDDVTKIVAATDGNLWITTYWRGVDYFDKKAG
KFIHYNTQTVPGLASDNIWSVVDGGDGKLYMGHVHHGFSVLSLKDKKVKNFMHDPEDPVSLPGNGVTCIYKDLSGNIWLG
TDRGLALFNPEAENFIHFHHSEDGVPHTVFDIRQFDGNKLWIAMEFGGIAILDLTQRMFLSPDQVRFQYIKEGDDEYSLS
NSTVRCLFQDSFKNVWAGMWGGGINFLSHESSYFNVYSYSPIQHSGSSLNNKTASSVCVARDGKLWIGTDGGGINVFDKG
KRVAVYKEETGDLTDNSIQAALCDSEGNLWFGSFMGGVDFYDVKKKSFHQIFPKDKTGEDVRALYEDAEYVWIGTSNGIY
KVRLHDKGIADHYTVENNLVRCISKDNLNRLWIGTFGGGLGVFDEHFQCVKLFNVTSLFPSNTINTVYMDSQNRMWIGTG
EGLVCFPSSQSWDYKVYRSEEGLSNVHIRAITEDNHGNIWVSTNKGISCLLKDKEVFYNYDHWDNVPMGNFMSGSVAEAK
DGTLYFGSINGLCRFNPDQVLEKRESPAAIITEMRIFGPLRDTDSNEKVMALEGQSEVRLSYMQNNFSVTFNIQNYALAD
QVEYAYMLKGLENSWYTVTDPNNVTFRNIPPGNYCFQVKTRIRNQEWADEIASLDIRIDPPVWLTWWAKLFYILSGVSVL
YFILHAYKKKLDMESLYELEKKNHEQEQELNNERLRFYTNITHELRTPLTLILGPLEDMQKSNSLSGKDSQKISVIHQSA
IRLLNLINQILEFRKTETQNKKLCVSRDNLAALVHEIGLKYKELNRKPEIDFCLEIEQEDMSLFFDKEVVTIMLDNLISN
AIKYTEKGTITLGLHQVVRNNIHHTEISVSDTGFGIAPDALPHIFDRYYQEGSEHQASGTGIGLALVKNLVVLHEGEIRV
ESSLNVGSTFYVSLLTDNTYPHVLHADSTEKTSDEKDEKEENIEPVHSGKRILLIVEDNRDICDYIVESFSDDFEVRTAA
NGEQGLEQALGCIPDIIVSDIMMPVMNGIVMCRKLKEDLRTSHIPIILLTAKDSLQDKEEGYQVGADSYLTKPFSATLLH
SRIHNLLESRKLLAERFNTNSILIDKRAAVTESMNKLDNEFLEKINKLIEDRLSSEKIDIGYLSDAMCMSNSTLYRKMKA
LTGLSTNEYIRKIKMQYAERLLLEGKYNISEVAFKVGINSTVYFRQCFKDEFGMAPSDYLKKIKPE
>Mature_1346_residues
MRKIFVLWLLLLSVVSLAQPYSVKQLGIEKGLSNNYVVSIAQDKQGFLWFATEEGLNKFDGTRFITYLKNEDLTRQGITG
NELNCLLDDPQDSILWIGTQRAGLNAYDYVNNTFLCYRHDGENPESLITDDVTKIVAATDGNLWITTYWRGVDYFDKKAG
KFIHYNTQTVPGLASDNIWSVVDGGDGKLYMGHVHHGFSVLSLKDKKVKNFMHDPEDPVSLPGNGVTCIYKDLSGNIWLG
TDRGLALFNPEAENFIHFHHSEDGVPHTVFDIRQFDGNKLWIAMEFGGIAILDLTQRMFLSPDQVRFQYIKEGDDEYSLS
NSTVRCLFQDSFKNVWAGMWGGGINFLSHESSYFNVYSYSPIQHSGSSLNNKTASSVCVARDGKLWIGTDGGGINVFDKG
KRVAVYKEETGDLTDNSIQAALCDSEGNLWFGSFMGGVDFYDVKKKSFHQIFPKDKTGEDVRALYEDAEYVWIGTSNGIY
KVRLHDKGIADHYTVENNLVRCISKDNLNRLWIGTFGGGLGVFDEHFQCVKLFNVTSLFPSNTINTVYMDSQNRMWIGTG
EGLVCFPSSQSWDYKVYRSEEGLSNVHIRAITEDNHGNIWVSTNKGISCLLKDKEVFYNYDHWDNVPMGNFMSGSVAEAK
DGTLYFGSINGLCRFNPDQVLEKRESPAAIITEMRIFGPLRDTDSNEKVMALEGQSEVRLSYMQNNFSVTFNIQNYALAD
QVEYAYMLKGLENSWYTVTDPNNVTFRNIPPGNYCFQVKTRIRNQEWADEIASLDIRIDPPVWLTWWAKLFYILSGVSVL
YFILHAYKKKLDMESLYELEKKNHEQEQELNNERLRFYTNITHELRTPLTLILGPLEDMQKSNSLSGKDSQKISVIHQSA
IRLLNLINQILEFRKTETQNKKLCVSRDNLAALVHEIGLKYKELNRKPEIDFCLEIEQEDMSLFFDKEVVTIMLDNLISN
AIKYTEKGTITLGLHQVVRNNIHHTEISVSDTGFGIAPDALPHIFDRYYQEGSEHQASGTGIGLALVKNLVVLHEGEIRV
ESSLNVGSTFYVSLLTDNTYPHVLHADSTEKTSDEKDEKEENIEPVHSGKRILLIVEDNRDICDYIVESFSDDFEVRTAA
NGEQGLEQALGCIPDIIVSDIMMPVMNGIVMCRKLKEDLRTSHIPIILLTAKDSLQDKEEGYQVGADSYLTKPFSATLLH
SRIHNLLESRKLLAERFNTNSILIDKRAAVTESMNKLDNEFLEKINKLIEDRLSSEKIDIGYLSDAMCMSNSTLYRKMKA
LTGLSTNEYIRKIKMQYAERLLLEGKYNISEVAFKVGINSTVYFRQCFKDEFGMAPSDYLKKIKPE

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=468, Percent_Identity=27.991452991453, Blast_Score=134, Evalue=4e-32,
Organism=Escherichia coli, GI1788713, Length=376, Percent_Identity=25.531914893617, Blast_Score=127, Evalue=6e-30,
Organism=Escherichia coli, GI145693157, Length=337, Percent_Identity=27.893175074184, Blast_Score=109, Evalue=1e-24,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=29.3859649122807, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI87081816, Length=356, Percent_Identity=25, Blast_Score=83, Evalue=9e-17,
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=28.3950617283951, Blast_Score=81, Evalue=4e-16,
Organism=Escherichia coli, GI1789149, Length=306, Percent_Identity=25.4901960784314, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI1790436, Length=268, Percent_Identity=29.8507462686567, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=26.5217391304348, Blast_Score=80, Evalue=8e-16,
Organism=Escherichia coli, GI1786783, Length=259, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786784, Length=136, Percent_Identity=33.0882352941176, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=28.8288288288288, Blast_Score=71, Evalue=6e-13,
Organism=Escherichia coli, GI1788394, Length=146, Percent_Identity=27.3972602739726, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789403, Length=222, Percent_Identity=25.2252252252252, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI87082012, Length=145, Percent_Identity=29.6551724137931, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1790860, Length=136, Percent_Identity=30.1470588235294, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786912, Length=258, Percent_Identity=25.5813953488372, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1789402, Length=118, Percent_Identity=35.5932203389831, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=229, Percent_Identity=26.6375545851528, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1790552, Length=120, Percent_Identity=35.8333333333333, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 153044; Mature: 153044

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIFVLWLLLLSVVSLAQPYSVKQLGIEKGLSNNYVVSIAQDKQGFLWFATEEGLNKFD
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCCCEEEEEEHHCCCCCC
GTRFITYLKNEDLTRQGITGNELNCLLDDPQDSILWIGTQRAGLNAYDYVNNTFLCYRHD
CCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHCCCCEEEEEEEC
GENPESLITDDVTKIVAATDGNLWITTYWRGVDYFDKKAGKFIHYNTQTVPGLASDNIWS
CCCHHHHHHHHHHEEEEECCCCEEEEEEECCCCHHHHCCCCEEEECCCCCCCCCCCCEEE
VVDGGDGKLYMGHVHHGFSVLSLKDKKVKNFMHDPEDPVSLPGNGVTCIYKDLSGNIWLG
EEECCCCEEEEEEECCCEEEEEECHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEE
TDRGLALFNPEAENFIHFHHSEDGVPHTVFDIRQFDGNKLWIAMEFGGIAILDLTQRMFL
CCCCEEEECCCCCCEEEEECCCCCCCCEEEEHEECCCCEEEEEEEECCEEEEEHHHHHHC
SPDQVRFQYIKEGDDEYSLSNSTVRCLFQDSFKNVWAGMWGGGINFLSHESSYFNVYSYS
CCHHHHHHHHHCCCCCEECCCCEEEEEEHHHHHHHHHHCCCCCCCEECCCCCEEEEEEEC
PIQHSGSSLNNKTASSVCVARDGKLWIGTDGGGINVFDKGKRVAVYKEETGDLTDNSIQA
CCCCCCCCCCCCCCCCEEEEECCEEEEECCCCCEEEEECCCEEEEEECCCCCCCCCCEEE
ALCDSEGNLWFGSFMGGVDFYDVKKKSFHQIFPKDKTGEDVRALYEDAEYVWIGTSNGIY
EEECCCCCEEEEHHHCCCCEECCCHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCCEE
KVRLHDKGIADHYTVENNLVRCISKDNLNRLWIGTFGGGLGVFDEHFQCVKLFNVTSLFP
EEEEECCCCCCCEEECCCHHEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
SNTINTVYMDSQNRMWIGTGEGLVCFPSSQSWDYKVYRSEEGLSNVHIRAITEDNHGNIW
CCCCEEEEECCCCEEEEECCCCEEEECCCCCCCEEEEECCCCCCCEEEEEEEECCCCEEE
VSTNKGISCLLKDKEVFYNYDHWDNVPMGNFMSGSVAEAKDGTLYFGSINGLCRFNPDQV
EECCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECHHHH
LEKRESPAAIITEMRIFGPLRDTDSNEKVMALEGQSEVRLSYMQNNFSVTFNIQNYALAD
HHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEECCEEEEEEECCEEEHH
QVEYAYMLKGLENSWYTVTDPNNVTFRNIPPGNYCFQVKTRIRNQEWADEIASLDIRIDP
HHHHHHHHHCCCCCCEEEECCCCEEEECCCCCCEEEEEEHHHCCHHHHHHHHEEEEEECC
PVWLTWWAKLFYILSGVSVLYFILHAYKKKLDMESLYELEKKNHEQEQELNNERLRFYTN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHCCCCCEEEEEC
ITHELRTPLTLILGPLEDMQKSNSLSGKDSQKISVIHQSAIRLLNLINQILEFRKTETQN
CHHHHCCCCEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KKLCVSRDNLAALVHEIGLKYKELNRKPEIDFCLEIEQEDMSLFFDKEVVTIMLDNLISN
CEEEEECCHHHHHHHHHCCCHHHCCCCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHH
AIKYTEKGTITLGLHQVVRNNIHHTEISVSDTGFGIAPDALPHIFDRYYQEGSEHQASGT
HHHHCCCCEEEEEHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
GIGLALVKNLVVLHEGEIRVESSLNVGSTFYVSLLTDNTYPHVLHADSTEKTSDEKDEKE
CHHHHHHHCEEEEECCCEEEECCCCCCCEEEEEEEECCCCCCEEECCCCCCCCCCHHHHH
ENIEPVHSGKRILLIVEDNRDICDYIVESFSDDFEVRTAANGEQGLEQALGCIPDIIVSD
HCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
IMMPVMNGIVMCRKLKEDLRTSHIPIILLTAKDSLQDKEEGYQVGADSYLTKPFSATLLH
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEECCCHHHCCCHHHHHHH
SRIHNLLESRKLLAERFNTNSILIDKRAAVTESMNKLDNEFLEKINKLIEDRLSSEKIDI
HHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
GYLSDAMCMSNSTLYRKMKALTGLSTNEYIRKIKMQYAERLLLEGKYNISEVAFKVGINS
EECCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCC
TVYFRQCFKDEFGMAPSDYLKKIKPE
HHHHHHHHHHHHCCCCHHHHHHCCCC
>Mature Secondary Structure
MRKIFVLWLLLLSVVSLAQPYSVKQLGIEKGLSNNYVVSIAQDKQGFLWFATEEGLNKFD
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCCCEEEEEEHHCCCCCC
GTRFITYLKNEDLTRQGITGNELNCLLDDPQDSILWIGTQRAGLNAYDYVNNTFLCYRHD
CCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHCCCCEEEEEEEC
GENPESLITDDVTKIVAATDGNLWITTYWRGVDYFDKKAGKFIHYNTQTVPGLASDNIWS
CCCHHHHHHHHHHEEEEECCCCEEEEEEECCCCHHHHCCCCEEEECCCCCCCCCCCCEEE
VVDGGDGKLYMGHVHHGFSVLSLKDKKVKNFMHDPEDPVSLPGNGVTCIYKDLSGNIWLG
EEECCCCEEEEEEECCCEEEEEECHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEE
TDRGLALFNPEAENFIHFHHSEDGVPHTVFDIRQFDGNKLWIAMEFGGIAILDLTQRMFL
CCCCEEEECCCCCCEEEEECCCCCCCCEEEEHEECCCCEEEEEEEECCEEEEEHHHHHHC
SPDQVRFQYIKEGDDEYSLSNSTVRCLFQDSFKNVWAGMWGGGINFLSHESSYFNVYSYS
CCHHHHHHHHHCCCCCEECCCCEEEEEEHHHHHHHHHHCCCCCCCEECCCCCEEEEEEEC
PIQHSGSSLNNKTASSVCVARDGKLWIGTDGGGINVFDKGKRVAVYKEETGDLTDNSIQA
CCCCCCCCCCCCCCCCEEEEECCEEEEECCCCCEEEEECCCEEEEEECCCCCCCCCCEEE
ALCDSEGNLWFGSFMGGVDFYDVKKKSFHQIFPKDKTGEDVRALYEDAEYVWIGTSNGIY
EEECCCCCEEEEHHHCCCCEECCCHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCCEE
KVRLHDKGIADHYTVENNLVRCISKDNLNRLWIGTFGGGLGVFDEHFQCVKLFNVTSLFP
EEEEECCCCCCCEEECCCHHEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
SNTINTVYMDSQNRMWIGTGEGLVCFPSSQSWDYKVYRSEEGLSNVHIRAITEDNHGNIW
CCCCEEEEECCCCEEEEECCCCEEEECCCCCCCEEEEECCCCCCCEEEEEEEECCCCEEE
VSTNKGISCLLKDKEVFYNYDHWDNVPMGNFMSGSVAEAKDGTLYFGSINGLCRFNPDQV
EECCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECHHHH
LEKRESPAAIITEMRIFGPLRDTDSNEKVMALEGQSEVRLSYMQNNFSVTFNIQNYALAD
HHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEECCEEEEEEECCEEEHH
QVEYAYMLKGLENSWYTVTDPNNVTFRNIPPGNYCFQVKTRIRNQEWADEIASLDIRIDP
HHHHHHHHHCCCCCCEEEECCCCEEEECCCCCCEEEEEEHHHCCHHHHHHHHEEEEEECC
PVWLTWWAKLFYILSGVSVLYFILHAYKKKLDMESLYELEKKNHEQEQELNNERLRFYTN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHCCCCCEEEEEC
ITHELRTPLTLILGPLEDMQKSNSLSGKDSQKISVIHQSAIRLLNLINQILEFRKTETQN
CHHHHCCCCEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KKLCVSRDNLAALVHEIGLKYKELNRKPEIDFCLEIEQEDMSLFFDKEVVTIMLDNLISN
CEEEEECCHHHHHHHHHCCCHHHCCCCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHH
AIKYTEKGTITLGLHQVVRNNIHHTEISVSDTGFGIAPDALPHIFDRYYQEGSEHQASGT
HHHHCCCCEEEEEHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
GIGLALVKNLVVLHEGEIRVESSLNVGSTFYVSLLTDNTYPHVLHADSTEKTSDEKDEKE
CHHHHHHHCEEEEECCCEEEECCCCCCCEEEEEEEECCCCCCEEECCCCCCCCCCHHHHH
ENIEPVHSGKRILLIVEDNRDICDYIVESFSDDFEVRTAANGEQGLEQALGCIPDIIVSD
HCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHH
IMMPVMNGIVMCRKLKEDLRTSHIPIILLTAKDSLQDKEEGYQVGADSYLTKPFSATLLH
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEECCCHHHCCCHHHHHHH
SRIHNLLESRKLLAERFNTNSILIDKRAAVTESMNKLDNEFLEKINKLIEDRLSSEKIDI
HHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
GYLSDAMCMSNSTLYRKMKALTGLSTNEYIRKIKMQYAERLLLEGKYNISEVAFKVGINS
EECCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEECCCC
TVYFRQCFKDEFGMAPSDYLKKIKPE
HHHHHHHHHHHHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA