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The map label for this gene is ribE [H]

Identifier: 148828402

GI number: 148828402

Start: 1856082

End: 1856696

Strand: Reverse

Name: ribE [H]

Synonym: CGSHiGG_10055

Alternate gene names: 148828402

Gene position: 1856696-1856082 (Counterclockwise)

Preceding gene: 148828406

Following gene: 148828396

Centisome position: 98.38

GC content: 37.07

Gene sequence:

>615_bases
ATGTTTACTGGAATTGTACAAGGCACCGCCCCCATCCACTCCATTAAAGAAAAGGCTAATTTTAGAACACAAGTGGTAAA
ATTACTACCTGAAATGCGTAAAGATCTGGAAATTGGCGCATCAATAGCAAATAACGGTGTATGTTTAACTGTAACTGAAA
TCAATGGCGATCTGGTTAGCTTTGATCTGATGCAAGAAACTTTAAAAATTACAAATCTCGGCACAGTAAAAGTGGGCGAT
TATGTGAATATCGAACGTGCTATGCAAATGGGAACGGAAATTGGCGGACATTTATTATCTGGTCATATTTATTGCACCGC
AAAAATTTCAGATATTATCGCTAGTGAAAATAACCGACAAATTTGGTTTGAGCTGCCAAGCGCAGATGTAATGAAATATA
TTTTAACGAAAGGATTTGTTGCGGTAGATGGCATTAGCCTCACTATTGGCGAAGTAAAAGGCACGCAATTCTGTGTGAAT
TTAATTCCTGAAACTTTGCAACGAACCTTAATGGGGCAGCGTAAAGTAGGCGATATTGTGAATATTGAAATCGATCCTCA
AACGCAAGCTATTGTAGATACTGTAGAAAATTATTTGCAGTCAAAAAATTTTTAG

Upstream 100 bases:

>100_bases
AATTTTAATCAAATTTTTAATATCAGCGTGGTATTGAGATAAAAGACGAAAATTCATAAATTTGATATACTGCTAAAAAT
TTTTAGAAAAGGAAAAAATT

Downstream 100 bases:

>100_bases
TTTATTTAAAAATATTAAGCAATTGAATAAAGTGAGAATAGTCATAAAACCTATTCTCACATCATTAAGTGTTACTGCAA
CGCTTTCTCAATTTTTTCAA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MFTGIVQGTAPIHSIKEKANFRTQVVKLLPEMRKDLEIGASIANNGVCLTVTEINGDLVSFDLMQETLKITNLGTVKVGD
YVNIERAMQMGTEIGGHLLSGHIYCTAKISDIIASENNRQIWFELPSADVMKYILTKGFVAVDGISLTIGEVKGTQFCVN
LIPETLQRTLMGQRKVGDIVNIEIDPQTQAIVDTVENYLQSKNF

Sequences:

>Translated_204_residues
MFTGIVQGTAPIHSIKEKANFRTQVVKLLPEMRKDLEIGASIANNGVCLTVTEINGDLVSFDLMQETLKITNLGTVKVGD
YVNIERAMQMGTEIGGHLLSGHIYCTAKISDIIASENNRQIWFELPSADVMKYILTKGFVAVDGISLTIGEVKGTQFCVN
LIPETLQRTLMGQRKVGDIVNIEIDPQTQAIVDTVENYLQSKNF
>Mature_204_residues
MFTGIVQGTAPIHSIKEKANFRTQVVKLLPEMRKDLEIGASIANNGVCLTVTEINGDLVSFDLMQETLKITNLGTVKVGD
YVNIERAMQMGTEIGGHLLSGHIYCTAKISDIIASENNRQIWFELPSADVMKYILTKGFVAVDGISLTIGEVKGTQFCVN
LIPETLQRTLMGQRKVGDIVNIEIDPQTQAIVDTVENYLQSKNF

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=202, Percent_Identity=65.8415841584158, Blast_Score=280, Evalue=6e-77,
Organism=Saccharomyces cerevisiae, GI6319733, Length=217, Percent_Identity=35.4838709677419, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22476; Mature: 22476

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVQGTAPIHSIKEKANFRTQVVKLLPEMRKDLEIGASIANNGVCLTVTEINGDLVS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEH
FDLMQETLKITNLGTVKVGDYVNIERAMQMGTEIGGHLLSGHIYCTAKISDIIASENNRQ
HHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCEEEECEEEEEEEHHHHHHCCCCCE
IWFELPSADVMKYILTKGFVAVDGISLTIGEVKGTQFCVNLIPETLQRTLMGQRKVGDIV
EEEECCCHHHHHHHHHCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
NIEIDPQTQAIVDTVENYLQSKNF
EEEECCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTGIVQGTAPIHSIKEKANFRTQVVKLLPEMRKDLEIGASIANNGVCLTVTEINGDLVS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEH
FDLMQETLKITNLGTVKVGDYVNIERAMQMGTEIGGHLLSGHIYCTAKISDIIASENNRQ
HHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCEEEECEEEEEEEHHHHHHCCCCCE
IWFELPSADVMKYILTKGFVAVDGISLTIGEVKGTQFCVNLIPETLQRTLMGQRKVGDIV
EEEECCCHHHHHHHHHCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
NIEIDPQTQAIVDTVENYLQSKNF
EEEECCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]