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The map label for this gene is lldP [C]

Identifier: 148828365

GI number: 148828365

Start: 1815995

End: 1817593

Strand: Reverse

Name: lldP [C]

Synonym: CGSHiGG_09830

Alternate gene names: 148828365

Gene position: 1817593-1815995 (Counterclockwise)

Preceding gene: 148828369

Following gene: 148828361

Centisome position: 96.31

GC content: 35.65

Gene sequence:

>1599_bases
ATGCTGTCTTTTATTCTAAGTATTTTTCCTATCGTTTTACTGATTTATCTTATGGTAAAAAGAAACGCGCTACCTTCTTA
TGTTGCCTTACCTTGGATTGCGACATTAGTTATGGGTGTTCATCTTTTACACTTTAATACAGATATTGTTACTATTAGTG
CAAATGTTGTTTCTGCAATTGTTGCGGTACAAACTCCTATTACAGTAATTTTTGGTGCGATTCTCTTTAACCGTTTCTCT
GAAATTTCAGGCGCAACGAATATTATGCGAAAATGGTTAGGAAATATTAATCCAAATCCCGTTGCACAATTAATGATTAT
TGGTTGGGCATTTGCCTTTATGATCGAAGGGGCAAGTGGTTTTGGTACACCAGCGGCAATTGCTGCACCTATTTTAGTGG
GATTAGGTTTTCATCCATTAAAAGTGGCGATGTTGGCACTTATTATGAACTCAGTTCCCGTATCCTTTGGTGCGGTAGGT
ACACCAACTTGGTTTGGTTTTGGTGCTTTAAAATTATCAGAAAATATGATTTTAGAAATTGGGTCTATTACAGCATTTAT
CCACTCCATTGCTGCACTTATTATCCCATTATTAGCACTTCGTATCTTAGTAAGTTGGGATGATATTCGTAAAAACATCG
TATTTATTTATATTAGCGTACTGGGTTGCGTAGTACCTTATTTCTTAATTGCTCAAGTCAATTACGAATTTCCATCACTC
GTTGGGGGGGCAATCGGCTTATTTATTTCCGTATGGGCTGCGAATCGCAATATTGGTTTAGCAAAAGTAACAAATAACCT
TGATAATAATGCGGTAAGTACGGGAGAAGTAGTTAAAGCATTATTCCCTACAGGTTTACTTATTGCATTTTTAATTGTGA
CTCGTATTCATCAATTACCATTCAAAGCAATGATGAATGACGCAACTATTTGGTTCTCAACCACATTAGGTTCCTTAGGA
TTATTTGAAATTAGTAAAGGTTTAATCTTTAGCTTAAAAAATATTTTTGGCTCAAATGTTTCATCAAGCTATAAACTTCT
TTACGTACCTGCATTGATTCCATTTGTCATTACAGTGCTCATTGCGATTCCTTTCTTTAAAATTTCCAGTTCAAATGTTA
AACAGATTTTTGTATCAAGTTTACAACAATCTAAAAATCCATTTATTGCCTTAATTGGTGCCTTAGTGATGGTAAACCTA
ATGTTAGTGGGTGGCGAACATTCTATGGTAAAAATTATTGGTCGAACTTTTGCTGAAATTTCTGGTAGTAACTGGACTAT
TTTCTCCTCTTTCTTAGGTGCGATTGGATCGTTTTTCTCGGGTTCAAATACCGTATCCAACCTAACATTTGGTAGTGTTC
AACTTTCTACCGCAGAAACCACAGGCATTTCTGTCGCACTTGTTCTTGCTTTACAATCTGTCGGTGGGGCAATGGGGAAT
ATGGTATGTATCAATAACATTGTAGCGGTAAGTTCTGTGTTAAATATTTCAAACCAAGAAGGCACAATTATTAAGAAAAC
CATTATACCGATGATCGTTTACGGTATTATTGCCGCACTTTGCGCGCTGTTCTTAGTACCTTTGTTTTATAATCTATAA

Upstream 100 bases:

>100_bases
TTTATGAGATATTGATCACATTTTCTTAAAATAGGTATATGCTTTTGCATATAAATCCATAAAATAACCACATCTTTTAA
TCTAACTCTGAGGATATTTT

Downstream 100 bases:

>100_bases
AATTCACGCCAAAAATGACCGCACTTTTGCGGTCATTTCCTATTTTTCTCTTTTATATTTCTACTATCAAAAATGAGCTT
TAACCCATTAAAGTGCGGTT

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MLSFILSIFPIVLLIYLMVKRNALPSYVALPWIATLVMGVHLLHFNTDIVTISANVVSAIVAVQTPITVIFGAILFNRFS
EISGATNIMRKWLGNINPNPVAQLMIIGWAFAFMIEGASGFGTPAAIAAPILVGLGFHPLKVAMLALIMNSVPVSFGAVG
TPTWFGFGALKLSENMILEIGSITAFIHSIAALIIPLLALRILVSWDDIRKNIVFIYISVLGCVVPYFLIAQVNYEFPSL
VGGAIGLFISVWAANRNIGLAKVTNNLDNNAVSTGEVVKALFPTGLLIAFLIVTRIHQLPFKAMMNDATIWFSTTLGSLG
LFEISKGLIFSLKNIFGSNVSSSYKLLYVPALIPFVITVLIAIPFFKISSSNVKQIFVSSLQQSKNPFIALIGALVMVNL
MLVGGEHSMVKIIGRTFAEISGSNWTIFSSFLGAIGSFFSGSNTVSNLTFGSVQLSTAETTGISVALVLALQSVGGAMGN
MVCINNIVAVSSVLNISNQEGTIIKKTIIPMIVYGIIAALCALFLVPLFYNL

Sequences:

>Translated_532_residues
MLSFILSIFPIVLLIYLMVKRNALPSYVALPWIATLVMGVHLLHFNTDIVTISANVVSAIVAVQTPITVIFGAILFNRFS
EISGATNIMRKWLGNINPNPVAQLMIIGWAFAFMIEGASGFGTPAAIAAPILVGLGFHPLKVAMLALIMNSVPVSFGAVG
TPTWFGFGALKLSENMILEIGSITAFIHSIAALIIPLLALRILVSWDDIRKNIVFIYISVLGCVVPYFLIAQVNYEFPSL
VGGAIGLFISVWAANRNIGLAKVTNNLDNNAVSTGEVVKALFPTGLLIAFLIVTRIHQLPFKAMMNDATIWFSTTLGSLG
LFEISKGLIFSLKNIFGSNVSSSYKLLYVPALIPFVITVLIAIPFFKISSSNVKQIFVSSLQQSKNPFIALIGALVMVNL
MLVGGEHSMVKIIGRTFAEISGSNWTIFSSFLGAIGSFFSGSNTVSNLTFGSVQLSTAETTGISVALVLALQSVGGAMGN
MVCINNIVAVSSVLNISNQEGTIIKKTIIPMIVYGIIAALCALFLVPLFYNL
>Mature_532_residues
MLSFILSIFPIVLLIYLMVKRNALPSYVALPWIATLVMGVHLLHFNTDIVTISANVVSAIVAVQTPITVIFGAILFNRFS
EISGATNIMRKWLGNINPNPVAQLMIIGWAFAFMIEGASGFGTPAAIAAPILVGLGFHPLKVAMLALIMNSVPVSFGAVG
TPTWFGFGALKLSENMILEIGSITAFIHSIAALIIPLLALRILVSWDDIRKNIVFIYISVLGCVVPYFLIAQVNYEFPSL
VGGAIGLFISVWAANRNIGLAKVTNNLDNNAVSTGEVVKALFPTGLLIAFLIVTRIHQLPFKAMMNDATIWFSTTLGSLG
LFEISKGLIFSLKNIFGSNVSSSYKLLYVPALIPFVITVLIAIPFFKISSSNVKQIFVSSLQQSKNPFIALIGALVMVNL
MLVGGEHSMVKIIGRTFAEISGSNWTIFSSFLGAIGSFFSGSNTVSNLTFGSVQLSTAETTGISVALVLALQSVGGAMGN
MVCINNIVAVSSVLNISNQEGTIIKKTIIPMIVYGIIAALCALFLVPLFYNL

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=543, Percent_Identity=25.5985267034991, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789347, Length=262, Percent_Identity=26.3358778625954, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 56967; Mature: 56967

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFILSIFPIVLLIYLMVKRNALPSYVALPWIATLVMGVHLLHFNTDIVTISANVVSAI
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCEEEEEHHHHHHH
VAVQTPITVIFGAILFNRFSEISGATNIMRKWLGNINPNPVAQLMIIGWAFAFMIEGASG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
FGTPAAIAAPILVGLGFHPLKVAMLALIMNSVPVSFGAVGTPTWFGFGALKLSENMILEI
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHEECCCHHEEH
GSITAFIHSIAALIIPLLALRILVSWDDIRKNIVFIYISVLGCVVPYFLIAQVNYEFPSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VGGAIGLFISVWAANRNIGLAKVTNNLDNNAVSTGEVVKALFPTGLLIAFLIVTRIHQLP
HHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
FKAMMNDATIWFSTTLGSLGLFEISKGLIFSLKNIFGSNVSSSYKLLYVPALIPFVITVL
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHH
IAIPFFKISSSNVKQIFVSSLQQSKNPFIALIGALVMVNLMLVGGEHSMVKIIGRTFAEI
HHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SGSNWTIFSSFLGAIGSFFSGSNTVSNLTFGSVQLSTAETTGISVALVLALQSVGGAMGN
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCEEEECCCCCCHHHHHHHHHHHHCCHHCC
MVCINNIVAVSSVLNISNQEGTIIKKTIIPMIVYGIIAALCALFLVPLFYNL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSFILSIFPIVLLIYLMVKRNALPSYVALPWIATLVMGVHLLHFNTDIVTISANVVSAI
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCEEEEEHHHHHHH
VAVQTPITVIFGAILFNRFSEISGATNIMRKWLGNINPNPVAQLMIIGWAFAFMIEGASG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
FGTPAAIAAPILVGLGFHPLKVAMLALIMNSVPVSFGAVGTPTWFGFGALKLSENMILEI
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHEECCCHHEEH
GSITAFIHSIAALIIPLLALRILVSWDDIRKNIVFIYISVLGCVVPYFLIAQVNYEFPSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VGGAIGLFISVWAANRNIGLAKVTNNLDNNAVSTGEVVKALFPTGLLIAFLIVTRIHQLP
HHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
FKAMMNDATIWFSTTLGSLGLFEISKGLIFSLKNIFGSNVSSSYKLLYVPALIPFVITVL
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHH
IAIPFFKISSSNVKQIFVSSLQQSKNPFIALIGALVMVNLMLVGGEHSMVKIIGRTFAEI
HHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SGSNWTIFSSFLGAIGSFFSGSNTVSNLTFGSVQLSTAETTGISVALVLALQSVGGAMGN
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCEEEECCCCCCHHHHHHHHHHHHCCHHCC
MVCINNIVAVSSVLNISNQEGTIIKKTIIPMIVYGIIAALCALFLVPLFYNL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]