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The map label for this gene is pabB [C]

Identifier: 148828324

GI number: 148828324

Start: 1768676

End: 1769647

Strand: Reverse

Name: pabB [C]

Synonym: CGSHiGG_09550

Alternate gene names: 148828324

Gene position: 1769647-1768676 (Counterclockwise)

Preceding gene: 148828329

Following gene: 148828323

Centisome position: 93.77

GC content: 34.57

Gene sequence:

>972_bases
ATGCAACATTTTATTGAACAGGCTAATCATTATGGCAAACAACGCACGCCATTTTTCTTTCTTATTGATTTTGAAAAAGA
AAAACCATTGATTTGTCCTCTCGAAAATTCTGCACAACAAGGCATTTATTTTGATATTTTAGGCAAAAGAAATTGCACAA
TTTCTCCACGACCTCTCCCTCTTAATTTTACCAAACATCCAATGCCTTTCTCGCATTATCAACAAGGTTTTGAACTTGTT
CAAAGTGAATTACAAAAAGGTAATTCTTATTTATTAAATCTCACCTACCCCACTGAAATTTCAGGTAATCTGTCACTTGA
ACAAATTTTTCATCAAACCAATGCACCTTATAAATTGTGGTTACAAGATCAATTCGTTTGCTTTTCGCCTGAATGTTTTG
TCAATATTCATGACAACAATATTTTTACCTATCCCATGAAAGGGACAATTAATGCCACCCTGCCCGATGCAGAAAATCAG
TTACTCGCAAATGAAAAAGAACAACGCGAACATTACACGATTGTTGATTTGATGCGTAACGATTTATCCATGGTGGCAGA
ACACATTCAAGTGAAAAAATTTCGTTATATCGATCGTATCAAGACCCAGAAAGGCGAAATACTGCAAACCAGTTCTGAAA
TTTACGGAAAATTGAATGAAAACTGGCAAAATCAAATTGGGGATATTTTAGAGAAACTGTTGCCTGCTGGGTCTATTAGT
GGCGCACCAAAAGAAAAAACCACACAAATTATTCAACAAGCAGAAAAACAAAAGCGCGGTTATTACACGGGAATTTTTGG
CATATTTGATGGCAAAACACTACAAAGTGCGGTAGCAATTCGATTTATTTCTCAAGTAGATGAAAAATTTTATTTTCATA
GTGGAGGTGGAATTACCATTCATAGCAATGTGCAAGATGAATATGAAGAATTATTAGAAAAAGTCTATTTACCGATTGAA
GGTGCTGATTAA

Upstream 100 bases:

>100_bases
TTAAAAGTAAAAGAATCGTGATTATTAATGATGAGTAATTTCATAACAGTTCGGTATTCGTTATAATCGGGTCATTTTAC
GCAAAATGGCACAAAGCACA

Downstream 100 bases:

>100_bases
TGTTCCCTCTATTTGAAACCCTTTGTATTGAAAACGGGAAAATTCAAAATATCGATTTACACCAAGTGCGATATGAACGT
AGTTTGCGTGAATATTATGG

Product: para-aminobenzoate synthase component I

Products: 4-amino-4-deoxychorismate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MQHFIEQANHYGKQRTPFFFLIDFEKEKPLICPLENSAQQGIYFDILGKRNCTISPRPLPLNFTKHPMPFSHYQQGFELV
QSELQKGNSYLLNLTYPTEISGNLSLEQIFHQTNAPYKLWLQDQFVCFSPECFVNIHDNNIFTYPMKGTINATLPDAENQ
LLANEKEQREHYTIVDLMRNDLSMVAEHIQVKKFRYIDRIKTQKGEILQTSSEIYGKLNENWQNQIGDILEKLLPAGSIS
GAPKEKTTQIIQQAEKQKRGYYTGIFGIFDGKTLQSAVAIRFISQVDEKFYFHSGGGITIHSNVQDEYEELLEKVYLPIE
GAD

Sequences:

>Translated_323_residues
MQHFIEQANHYGKQRTPFFFLIDFEKEKPLICPLENSAQQGIYFDILGKRNCTISPRPLPLNFTKHPMPFSHYQQGFELV
QSELQKGNSYLLNLTYPTEISGNLSLEQIFHQTNAPYKLWLQDQFVCFSPECFVNIHDNNIFTYPMKGTINATLPDAENQ
LLANEKEQREHYTIVDLMRNDLSMVAEHIQVKKFRYIDRIKTQKGEILQTSSEIYGKLNENWQNQIGDILEKLLPAGSIS
GAPKEKTTQIIQQAEKQKRGYYTGIFGIFDGKTLQSAVAIRFISQVDEKFYFHSGGGITIHSNVQDEYEELLEKVYLPIE
GAD
>Mature_323_residues
MQHFIEQANHYGKQRTPFFFLIDFEKEKPLICPLENSAQQGIYFDILGKRNCTISPRPLPLNFTKHPMPFSHYQQGFELV
QSELQKGNSYLLNLTYPTEISGNLSLEQIFHQTNAPYKLWLQDQFVCFSPECFVNIHDNNIFTYPMKGTINATLPDAENQ
LLANEKEQREHYTIVDLMRNDLSMVAEHIQVKKFRYIDRIKTQKGEILQTSSEIYGKLNENWQNQIGDILEKLLPAGSIS
GAPKEKTTQIIQQAEKQKRGYYTGIFGIFDGKTLQSAVAIRFISQVDEKFYFHSGGGITIHSNVQDEYEELLEKVYLPIE
GAD

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To the C-terminal of para-aminobenzoate synthase component I [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=264, Percent_Identity=29.9242424242424, Blast_Score=105, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6320935, Length=220, Percent_Identity=28.1818181818182, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324361, Length=279, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR015890 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: 6.3.5.8

Molecular weight: Translated: 37301; Mature: 37301

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHFIEQANHYGKQRTPFFFLIDFEKEKPLICPLENSAQQGIYFDILGKRNCTISPRPLP
CCHHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCC
LNFTKHPMPFSHYQQGFELVQSELQKGNSYLLNLTYPTEISGNLSLEQIFHQTNAPYKLW
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCEEEE
LQDQFVCFSPECFVNIHDNNIFTYPMKGTINATLPDAENQLLANEKEQREHYTIVDLMRN
EECCEEEECCCEEEEEECCEEEEEECCCEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHH
DLSMVAEHIQVKKFRYIDRIKTQKGEILQTSSEIYGKLNENWQNQIGDILEKLLPAGSIS
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
GAPKEKTTQIIQQAEKQKRGYYTGIFGIFDGKTLQSAVAIRFISQVDEKFYFHSGGGITI
CCCHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCCEEE
HSNVQDEYEELLEKVYLPIEGAD
ECCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQHFIEQANHYGKQRTPFFFLIDFEKEKPLICPLENSAQQGIYFDILGKRNCTISPRPLP
CCHHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCC
LNFTKHPMPFSHYQQGFELVQSELQKGNSYLLNLTYPTEISGNLSLEQIFHQTNAPYKLW
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCEEEE
LQDQFVCFSPECFVNIHDNNIFTYPMKGTINATLPDAENQLLANEKEQREHYTIVDLMRN
EECCEEEECCCEEEEEECCEEEEEECCCEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHH
DLSMVAEHIQVKKFRYIDRIKTQKGEILQTSSEIYGKLNENWQNQIGDILEKLLPAGSIS
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
GAPKEKTTQIIQQAEKQKRGYYTGIFGIFDGKTLQSAVAIRFISQVDEKFYFHSGGGITI
CCCHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCCEEE
HSNVQDEYEELLEKVYLPIEGAD
ECCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chorismate; L-glutamine

Specific reaction: chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate

General reaction: Lyases; Carbon-Carbon Lyases; Oxo-Acid-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]