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The map label for this gene is murD [H]

Identifier: 148828297

GI number: 148828297

Start: 1733822

End: 1735006

Strand: Direct

Name: murD [H]

Synonym: CGSHiGG_09345

Alternate gene names: 148828297

Gene position: 1733822-1735006 (Clockwise)

Preceding gene: 148828296

Following gene: 148828298

Centisome position: 91.87

GC content: 35.02

Gene sequence:

>1185_bases
ATGGAATTTTTACAGAACATCAAAAAAAATTACGATGAATGGACACGCATCACACCGCAAGGTTTGTTGTATGATCGCGC
ACTATTTTGGTTATTTGTTATTTTGCTTTTAATTGGTTTAGTGGCAGTAACATCTGCTTCTATTCCTTATAGCTCTCGTT
TATTTAATGATCCTTTTTACTTTGCAAAACGCGACGCTATTTATGTGCTACTTTCTTTGCTCACTTGTTATATTTCATTA
CAAATTTCTTCTTCGCAATGGGAAAAATGGCACGCTAAAATTTTTTTATTTTCTGTCATATTATTATTGCTTGTCCCTTT
TATCGGTACATCGGTTAATGGCGCAAAACGTTGGATTTCGTTGGGAATCTTAAACTTTCAACCTGCAGAATTTGCAAAAT
TGGCTTTGACTTGTTTTTTAGCAAGTTATTTCACTCGTCGTTATGATGAAGTGCGGTCGCGACATGTTAGTATTTTTAAA
CCGTTTATTGTTATGCTTGTATTGGGTTGTTTTCTTTTATTGCAACCTGATTTAGGTAGTACAGTCGTGCTATTTATTAT
TATGTCTGGGATGCTTTTTATCGTAGGGGCGAAAATTTTACAGTTTGTAGGATTGATAGCATTAGGTGGAATCTTATTCG
TTTGGCTAGTATTGACCGCCTCTTATCGGTTAAAGCGATTTATAGGTTTTTTAGAACCCTTTAAAGATCCTTATGGCACT
GGTTTCCAATTAACAAACTCTCTTATAGCATTTGGGCGGGGAGAAATTACTGGCGAAGGATTAGGTAATTCAATTCAAAA
ATTAGATTATCTGCCTGAAGCACATACCGATTTCATTATGGCGATTATCGGCGAAGAATTTGGATTTATCGGTATATTGA
TTGTTATTCTTTTATTAGGTTTATTAATTTTTCGTGCAATGAAAATTGGACGAGAATCCTTAATGTTAGAACAACGTTTT
CGAGGTTTTTTTGCATTAGGTATTGGTTTTTGGATTTTCTTTCAAGGCTTTGTGAATTTAGGTATGGCTCTTGGAATGCT
ACCAACTAAAGGTTTAACCTTTCCACTCGTGAGTTATGGTGGTTCGAGTATTATCATTATGTCCGCCACTATTGGTATTT
TATTGCGAATTGATCACGAAAATCGTTTATTTCGTATAGGTCAAGCACGCTTGCGTGATGATTAG

Upstream 100 bases:

>100_bases
TGTGCAAGTCTCGATCAGTTTGCTTCTTTTGAAAAGCGCGGCGAAGAATTTACGCATTTAGCTCAATATTCAGTCTAATT
TAGTCATTAATAAAAATAAG

Downstream 100 bases:

>100_bases
AGATAAAAAAGATGAAAAATAAAAAATTATTAGTGATGGCGGGTGGTACTGGCGGTCATGTTTTTCCTGCCATTGCAGTT
GCTCAAACTTTACAAAAACA

Product: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MEFLQNIKKNYDEWTRITPQGLLYDRALFWLFVILLLIGLVAVTSASIPYSSRLFNDPFYFAKRDAIYVLLSLLTCYISL
QISSSQWEKWHAKIFLFSVILLLLVPFIGTSVNGAKRWISLGILNFQPAEFAKLALTCFLASYFTRRYDEVRSRHVSIFK
PFIVMLVLGCFLLLQPDLGSTVVLFIIMSGMLFIVGAKILQFVGLIALGGILFVWLVLTASYRLKRFIGFLEPFKDPYGT
GFQLTNSLIAFGRGEITGEGLGNSIQKLDYLPEAHTDFIMAIIGEEFGFIGILIVILLLGLLIFRAMKIGRESLMLEQRF
RGFFALGIGFWIFFQGFVNLGMALGMLPTKGLTFPLVSYGGSSIIIMSATIGILLRIDHENRLFRIGQARLRDD

Sequences:

>Translated_394_residues
MEFLQNIKKNYDEWTRITPQGLLYDRALFWLFVILLLIGLVAVTSASIPYSSRLFNDPFYFAKRDAIYVLLSLLTCYISL
QISSSQWEKWHAKIFLFSVILLLLVPFIGTSVNGAKRWISLGILNFQPAEFAKLALTCFLASYFTRRYDEVRSRHVSIFK
PFIVMLVLGCFLLLQPDLGSTVVLFIIMSGMLFIVGAKILQFVGLIALGGILFVWLVLTASYRLKRFIGFLEPFKDPYGT
GFQLTNSLIAFGRGEITGEGLGNSIQKLDYLPEAHTDFIMAIIGEEFGFIGILIVILLLGLLIFRAMKIGRESLMLEQRF
RGFFALGIGFWIFFQGFVNLGMALGMLPTKGLTFPLVSYGGSSIIIMSATIGILLRIDHENRLFRIGQARLRDD
>Mature_394_residues
MEFLQNIKKNYDEWTRITPQGLLYDRALFWLFVILLLIGLVAVTSASIPYSSRLFNDPFYFAKRDAIYVLLSLLTCYISL
QISSSQWEKWHAKIFLFSVILLLLVPFIGTSVNGAKRWISLGILNFQPAEFAKLALTCFLASYFTRRYDEVRSRHVSIFK
PFIVMLVLGCFLLLQPDLGSTVVLFIIMSGMLFIVGAKILQFVGLIALGGILFVWLVLTASYRLKRFIGFLEPFKDPYGT
GFQLTNSLIAFGRGEITGEGLGNSIQKLDYLPEAHTDFIMAIIGEEFGFIGILIVILLLGLLIFRAMKIGRESLMLEQRF
RGFFALGIGFWIFFQGFVNLGMALGMLPTKGLTFPLVSYGGSSIIIMSATIGILLRIDHENRLFRIGQARLRDD

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=371, Percent_Identity=52.8301886792453, Blast_Score=391, Evalue=1e-110,
Organism=Escherichia coli, GI1786853, Length=325, Percent_Identity=34.1538461538462, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44539; Mature: 44539

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEEEEEEEEEEEEEECCCCCHHHHCHHHCCCC
>Mature Secondary Structure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CCEEEEEEEEEEEEEEECCCCCHHHHCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]