Click here to switch to the map view.

The map label for this gene is xylB [H]

Identifier: 148828274

GI number: 148828274

Start: 1708047

End: 1709525

Strand: Direct

Name: xylB [H]

Synonym: CGSHiGG_09220

Alternate gene names: 148828274

Gene position: 1708047-1709525 (Clockwise)

Preceding gene: 148828273

Following gene: 148828279

Centisome position: 90.51

GC content: 37.19

Gene sequence:

>1479_bases
ATGTATATAGGAATTGATTGTGGCACACAAGGAACAAAGGCGATAGTGCTTGATTCTGTCCAAAAAAAAGTGATTGGAGT
TGGTTACGCAAAACATGGATTAATTACACAATCCAATGGAAGACGTGAACAACAACCAAATTGGTGGATTGAGGCATTAC
AACAAGCATTACAAATTGCATTGAAACAAGCAAAAAATTCACCGCACTTTTCACCTAATTTAGTGAAGGGAATAGGAATT
TCAGGACAACAACATGGACTGGTAATGTTAGATAAAAACGATCGTCCTCTATATAAGGCTAAGCTTTGGTGTGATACAGA
AACCGCTACGGAAAATGATATACTGATCGAAAAATTAGGCGGACAAACGGCCGCATTTGAAAAATTAGGTATCATTTGCC
AAACTGGTTACACGGCTTCAAAACTGAGTTGGTTTCGTCAAAATTATCCTGATAAATTTGCCAATATTCGCAAAATTATG
CTGCCACACGATTATCTAAATTATTGGCTAACAGGAAAATTCTGCACTGAATTTGGTGATGCTTCCGGTAGTGGTTATTT
CGATGTTGTGAAAAGAGAATGGAAAAGAGAAGTCTTCAAATATCTTGCGCCAGAATTAAATATGGATGAAGTGTTACCTA
AATTACTTTCTGCCGAACAAAAAATCGGTGTGATTAAACCTGAAATTGCGACTTTATTTGGTTTTAATGATAATGTCATC
GTCTCCACAGGTGGAGGCGATAATATGATGGGAGCAATTGGTACAGGAAATATTCGAGAAGGGATTGCTACGATGAGTCT
CGGTACTTCTGGTACCTTGTATGCTTATACGCAAAAGCCATTACTTAATTTACCACCAATGATCGCAAATTTTTGTTCAA
GTAATAATGGCTGGTTACCACTAGTTTGTGTGATGAATATAACCTCCTCAAATAAACAGCTAATGAATTTGCTAAATATT
GATATTGAAGAATTAAATCAACTTGCTCAACAAGCACCTATCGGCGCAAATGGCATCACTATTTTACCATTCTTTAATGG
TGAAAGAGTTCCACCTTTACCCAATACAAAAGCGAGCATTTTAGGATTAGATTCAAGTAATTTCACACGAGAAAATCTTT
GTCGAGCAATGATGGAAAGTGCCACTTTTACGCTTCGCTATGGTTTAGATTTATTTCGTCAAGCTGGCCTCAAAACCTCA
CAAATTCGCCTAATTGGAGGTGGCGCGAAAAGCTCATTTTGGCGGCAAATGATTGCTGATGTGATGAATTCTGAAGTGGT
ATGTTTGCAGGAAGAAGCTGCTGCATTAGGAGGAGCAATTCAAGCTATGTGGGCAAATGGAGAAGGAGAACTGGAATTTT
TATGCGAAACCTTCATTCACTTAGATGAAAACTCCAAAACTTATCCCAACTTATCACAGGTGAAAAATTATCAAAGTGCT
TACGAGCGTTATTTAAAACATTTATCACAATTATACTAA

Upstream 100 bases:

>100_bases
AAGAATATTTGGAAAATTTGGTAAACCAAGTTATTTATAGCTAAAAATGAAGCAAAAGTGCGGTTGTATTTCACCGCACT
TTTTTATTTTAGGAGACATT

Downstream 100 bases:

>100_bases
ATAAAATCCCCTATACCGAGAGTCTATAGGGGATTTACTACATTAATAATTTATTTTCTATTCAACCACGCCATATATTC
AGCCACGCCTTCCGCGACTG

Product: xylose isomerase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MYIGIDCGTQGTKAIVLDSVQKKVIGVGYAKHGLITQSNGRREQQPNWWIEALQQALQIALKQAKNSPHFSPNLVKGIGI
SGQQHGLVMLDKNDRPLYKAKLWCDTETATENDILIEKLGGQTAAFEKLGIICQTGYTASKLSWFRQNYPDKFANIRKIM
LPHDYLNYWLTGKFCTEFGDASGSGYFDVVKREWKREVFKYLAPELNMDEVLPKLLSAEQKIGVIKPEIATLFGFNDNVI
VSTGGGDNMMGAIGTGNIREGIATMSLGTSGTLYAYTQKPLLNLPPMIANFCSSNNGWLPLVCVMNITSSNKQLMNLLNI
DIEELNQLAQQAPIGANGITILPFFNGERVPPLPNTKASILGLDSSNFTRENLCRAMMESATFTLRYGLDLFRQAGLKTS
QIRLIGGGAKSSFWRQMIADVMNSEVVCLQEEAAALGGAIQAMWANGEGELEFLCETFIHLDENSKTYPNLSQVKNYQSA
YERYLKHLSQLY

Sequences:

>Translated_492_residues
MYIGIDCGTQGTKAIVLDSVQKKVIGVGYAKHGLITQSNGRREQQPNWWIEALQQALQIALKQAKNSPHFSPNLVKGIGI
SGQQHGLVMLDKNDRPLYKAKLWCDTETATENDILIEKLGGQTAAFEKLGIICQTGYTASKLSWFRQNYPDKFANIRKIM
LPHDYLNYWLTGKFCTEFGDASGSGYFDVVKREWKREVFKYLAPELNMDEVLPKLLSAEQKIGVIKPEIATLFGFNDNVI
VSTGGGDNMMGAIGTGNIREGIATMSLGTSGTLYAYTQKPLLNLPPMIANFCSSNNGWLPLVCVMNITSSNKQLMNLLNI
DIEELNQLAQQAPIGANGITILPFFNGERVPPLPNTKASILGLDSSNFTRENLCRAMMESATFTLRYGLDLFRQAGLKTS
QIRLIGGGAKSSFWRQMIADVMNSEVVCLQEEAAALGGAIQAMWANGEGELEFLCETFIHLDENSKTYPNLSQVKNYQSA
YERYLKHLSQLY
>Mature_492_residues
MYIGIDCGTQGTKAIVLDSVQKKVIGVGYAKHGLITQSNGRREQQPNWWIEALQQALQIALKQAKNSPHFSPNLVKGIGI
SGQQHGLVMLDKNDRPLYKAKLWCDTETATENDILIEKLGGQTAAFEKLGIICQTGYTASKLSWFRQNYPDKFANIRKIM
LPHDYLNYWLTGKFCTEFGDASGSGYFDVVKREWKREVFKYLAPELNMDEVLPKLLSAEQKIGVIKPEIATLFGFNDNVI
VSTGGGDNMMGAIGTGNIREGIATMSLGTSGTLYAYTQKPLLNLPPMIANFCSSNNGWLPLVCVMNITSSNKQLMNLLNI
DIEELNQLAQQAPIGANGITILPFFNGERVPPLPNTKASILGLDSSNFTRENLCRAMMESATFTLRYGLDLFRQAGLKTS
QIRLIGGGAKSSFWRQMIADVMNSEVVCLQEEAAALGGAIQAMWANGEGELEFLCETFIHLDENSKTYPNLSQVKNYQSA
YERYLKHLSQLY

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=449, Percent_Identity=22.9398663697105, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI41393575, Length=445, Percent_Identity=23.1460674157303, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI189409120, Length=449, Percent_Identity=22.9398663697105, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4504007, Length=449, Percent_Identity=22.9398663697105, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI18860918, Length=468, Percent_Identity=21.7948717948718, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1789987, Length=499, Percent_Identity=33.0661322645291, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1790005, Length=502, Percent_Identity=26.0956175298805, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787789, Length=520, Percent_Identity=23.4615384615385, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789168, Length=462, Percent_Identity=22.2943722943723, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17554530, Length=510, Percent_Identity=22.5490196078431, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=445, Percent_Identity=21.123595505618, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356607, Length=500, Percent_Identity=24, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24655555, Length=507, Percent_Identity=22.4852071005917, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24655560, Length=507, Percent_Identity=22.4852071005917, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24655570, Length=507, Percent_Identity=22.4852071005917, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24655574, Length=507, Percent_Identity=22.4852071005917, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24655565, Length=507, Percent_Identity=22.4852071005917, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54591; Mature: 54591

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIGIDCGTQGTKAIVLDSVQKKVIGVGYAKHGLITQSNGRREQQPNWWIEALQQALQIA
CEEEEECCCCCCCEEEHHHHHHHHHHCCCHHCCCEECCCCCCCCCCCHHHHHHHHHHHHH
LKQAKNSPHFSPNLVKGIGISGQQHGLVMLDKNDRPLYKAKLWCDTETATENDILIEKLG
HHHHCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCEEEECCC
GQTAAFEKLGIICQTGYTASKLSWFRQNYPDKFANIRKIMLPHDYLNYWLTGKFCTEFGD
CCHHHHHHHCEEEECCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHEECHHHHHHCCC
ASGSGYFDVVKREWKREVFKYLAPELNMDEVLPKLLSAEQKIGVIKPEIATLFGFNDNVI
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHCCCCCCCHHHEECCCCCEE
VSTGGGDNMMGAIGTGNIREGIATMSLGTSGTLYAYTQKPLLNLPPMIANFCSSNNGWLP
EECCCCCCCEEECCCCCHHHCCEEEECCCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEE
LVCVMNITSSNKQLMNLLNIDIEELNQLAQQAPIGANGITILPFFNGERVPPLPNTKASI
EEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEE
LGLDSSNFTRENLCRAMMESATFTLRYGLDLFRQAGLKTSQIRLIGGGAKSSFWRQMIAD
EECCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
VMNSEVVCLQEEAAALGGAIQAMWANGEGELEFLCETFIHLDENSKTYPNLSQVKNYQSA
HHCCCEEEEEHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
YERYLKHLSQLY
HHHHHHHHHHCC
>Mature Secondary Structure
MYIGIDCGTQGTKAIVLDSVQKKVIGVGYAKHGLITQSNGRREQQPNWWIEALQQALQIA
CEEEEECCCCCCCEEEHHHHHHHHHHCCCHHCCCEECCCCCCCCCCCHHHHHHHHHHHHH
LKQAKNSPHFSPNLVKGIGISGQQHGLVMLDKNDRPLYKAKLWCDTETATENDILIEKLG
HHHHCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCCCEEEECCC
GQTAAFEKLGIICQTGYTASKLSWFRQNYPDKFANIRKIMLPHDYLNYWLTGKFCTEFGD
CCHHHHHHHCEEEECCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHEECHHHHHHCCC
ASGSGYFDVVKREWKREVFKYLAPELNMDEVLPKLLSAEQKIGVIKPEIATLFGFNDNVI
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHCCCCCCCHHHEECCCCCEE
VSTGGGDNMMGAIGTGNIREGIATMSLGTSGTLYAYTQKPLLNLPPMIANFCSSNNGWLP
EECCCCCCCEEECCCCCHHHCCEEEECCCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEE
LVCVMNITSSNKQLMNLLNIDIEELNQLAQQAPIGANGITILPFFNGERVPPLPNTKASI
EEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEE
LGLDSSNFTRENLCRAMMESATFTLRYGLDLFRQAGLKTSQIRLIGGGAKSSFWRQMIAD
EECCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
VMNSEVVCLQEEAAALGGAIQAMWANGEGELEFLCETFIHLDENSKTYPNLSQVKNYQSA
HHCCCEEEEEHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
YERYLKHLSQLY
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]