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The map label for this gene is corA

Identifier: 148828201

GI number: 148828201

Start: 1629008

End: 1629955

Strand: Direct

Name: corA

Synonym: CGSHiGG_08795

Alternate gene names: 148828201

Gene position: 1629008-1629955 (Clockwise)

Preceding gene: 148828200

Following gene: 148828202

Centisome position: 86.32

GC content: 38.4

Gene sequence:

>948_bases
ATGATCAACGCGTTTGCTATCAATGATTCCCGCTTGGTTCGCATTGACGAAGACCAAACTGATCTCAATACTGCCATTTG
GCTTGATTTACTTGAGCCAACAGGCGAAGAACGTGAAATACTACAAGAAGGCTTAGGTCAGAGCCTAGCCTCTTTTCTAG
AATTGGAAGATATTGAAGCTTCCGCCCGTTTCTTTGAAGATGAAGATGGTTTACACCTGCACTCATTTTTTTATTGCGAA
GATGAAGACAATTATGCTGATTTAGCGAGCGTCGCTTTTACTATTCGTGATGGTCGTTTATTTACGTTGCGTGATCGCGA
GCTACCCGCATTCCGTTTATATCGTATGCGTTCACGTAGCCAGCGTTTGTTAGAATGCAATTCCTATGAAGTTTTACTGG
ATTTATTTGAAACGAAAATTGAGCAATTAGCGGACGTGATTGAAAATATTTATGCAGATTTGGAAGAGTTAAGTCGCGTT
ATTTTAAACGGAAAACAAGATGAAGCCTTTGATGAAGCATTAAATACACTCACGGAACAAGAAGATACGAGCTCAAAAGT
TCGTTTGTGTTTGATGGATACTCAACGTGCATTAGGTTTCTTGGTTCGCAAAACGCGCTTACCCACAAACCAGTTAGAAC
AAGCACGAGAAATCTTACGAGATATTGAATCTTTGCAACCGCATAATGAATCCTTGTTCCAAAAAGTGAACTTTTTAATG
CAAGCTGCAATGGGTTACATCAATATTGAGCAGAACAAAATTATGAAATTTTTCTCAGTTGTTTCTGTGATGTTCCTTCC
TGCAACATTAGTTGCATCCACTTATGGTATGAACTTTGATTTTATGCCTGAATTACATTTTAAATATGGCTATCCAATGG
CAATTGGATTAATGATCGCAGCCGCACTGACACCATATATTTATTTTAGAAGAAAAGGATGGTTATGA

Upstream 100 bases:

>100_bases
CGGCATCTCTTAACGAAAACTTTGCGATTTTTAACCGCACTTTCGTTTCCTCTTTAATTTGTTCACTGTTAGCTGTTCAT
AATCCCACAAGGAGTATGAA

Downstream 100 bases:

>100_bases
TGGAATTATCCCAAACCGCATTATTTATCGGATCAATTATTAATCTTTACGCACTTGTATTAATCTTACGAGCTTGGTTG
CAGTTTGCTCGTGTGGATTA

Product: magnesium/nickel/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MINAFAINDSRLVRIDEDQTDLNTAIWLDLLEPTGEEREILQEGLGQSLASFLELEDIEASARFFEDEDGLHLHSFFYCE
DEDNYADLASVAFTIRDGRLFTLRDRELPAFRLYRMRSRSQRLLECNSYEVLLDLFETKIEQLADVIENIYADLEELSRV
ILNGKQDEAFDEALNTLTEQEDTSSKVRLCLMDTQRALGFLVRKTRLPTNQLEQAREILRDIESLQPHNESLFQKVNFLM
QAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFDFMPELHFKYGYPMAIGLMIAAALTPYIYFRRKGWL

Sequences:

>Translated_315_residues
MINAFAINDSRLVRIDEDQTDLNTAIWLDLLEPTGEEREILQEGLGQSLASFLELEDIEASARFFEDEDGLHLHSFFYCE
DEDNYADLASVAFTIRDGRLFTLRDRELPAFRLYRMRSRSQRLLECNSYEVLLDLFETKIEQLADVIENIYADLEELSRV
ILNGKQDEAFDEALNTLTEQEDTSSKVRLCLMDTQRALGFLVRKTRLPTNQLEQAREILRDIESLQPHNESLFQKVNFLM
QAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFDFMPELHFKYGYPMAIGLMIAAALTPYIYFRRKGWL
>Mature_315_residues
MINAFAINDSRLVRIDEDQTDLNTAIWLDLLEPTGEEREILQEGLGQSLASFLELEDIEASARFFEDEDGLHLHSFFYCE
DEDNYADLASVAFTIRDGRLFTLRDRELPAFRLYRMRSRSQRLLECNSYEVLLDLFETKIEQLADVIENIYADLEELSRV
ILNGKQDEAFDEALNTLTEQEDTSSKVRLCLMDTQRALGFLVRKTRLPTNQLEQAREILRDIESLQPHNESLFQKVNFLM
QAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFDFMPELHFKYGYPMAIGLMIAAALTPYIYFRRKGWL

Specific function: Mediates influx of magnesium ions

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family

Homologues:

Organism=Escherichia coli, GI2367297, Length=316, Percent_Identity=70.253164556962, Blast_Score=454, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CORA_HAEI8 (Q4QLP6)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_248711.1
- ProteinModelPortal:   Q4QLP6
- STRING:   Q4QLP6
- GeneID:   3430476
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI1195
- eggNOG:   COG0598
- HOGENOM:   HBG350378
- OMA:   TQGFINI
- PhylomeDB:   Q4QLP6
- ProtClustDB:   PRK11085
- BioCyc:   HINF281310:NTHI1195-MONOMER
- InterPro:   IPR004488
- InterPro:   IPR002523
- PANTHER:   PTHR21535:SF1
- TIGRFAMs:   TIGR00383

Pfam domain/function: PF01544 CorA

EC number: NA

Molecular weight: Translated: 36576; Mature: 36576

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12673b6c)-; HASH(0x1301fc74)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINAFAINDSRLVRIDEDQTDLNTAIWLDLLEPTGEEREILQEGLGQSLASFLELEDIEA
CCEEEEECCCEEEEECCCCCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SARFFEDEDGLHLHSFFYCEDEDNYADLASVAFTIRDGRLFTLRDRELPAFRLYRMRSRS
HHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHEEEECCEEEEEECCCCCHHHHHHHHHHH
QRLLECNSYEVLLDLFETKIEQLADVIENIYADLEELSRVILNGKQDEAFDEALNTLTEQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
EDTSSKVRLCLMDTQRALGFLVRKTRLPTNQLEQAREILRDIESLQPHNESLFQKVNFLM
CCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFDFMPELHFKYGYPMAIGLMIA
HHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHH
AALTPYIYFRRKGWL
HHHHHHHHHHCCCCH
>Mature Secondary Structure
MINAFAINDSRLVRIDEDQTDLNTAIWLDLLEPTGEEREILQEGLGQSLASFLELEDIEA
CCEEEEECCCEEEEECCCCCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SARFFEDEDGLHLHSFFYCEDEDNYADLASVAFTIRDGRLFTLRDRELPAFRLYRMRSRS
HHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHEEEECCEEEEEECCCCCHHHHHHHHHHH
QRLLECNSYEVLLDLFETKIEQLADVIENIYADLEELSRVILNGKQDEAFDEALNTLTEQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
EDTSSKVRLCLMDTQRALGFLVRKTRLPTNQLEQAREILRDIESLQPHNESLFQKVNFLM
CCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFDFMPELHFKYGYPMAIGLMIA
HHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHH
AALTPYIYFRRKGWL
HHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA