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The map label for this gene is prmA [H]

Identifier: 148828153

GI number: 148828153

Start: 1564120

End: 1565007

Strand: Direct

Name: prmA [H]

Synonym: CGSHiGG_08465

Alternate gene names: 148828153

Gene position: 1564120-1565007 (Clockwise)

Preceding gene: 148828152

Following gene: 148828154

Centisome position: 82.88

GC content: 42.34

Gene sequence:

>888_bases
ATGGCTTGGATTCAAATTCGCCTGAACAGCACCAATGAAAAAGCAGAACAAATGAGTGATTTTTTAGAAGAAATCGGCTC
CGTCTCTGTAACTTTTATGGATAGTCAAGATACACCGATTTTTGAGCCTTTGCCGGGCGAAACGCGTTTATGGGGTAATA
CCGATGTTATTGCACTATTTGATGCAGAAACAGATATGGCAGAAATTGTCCGCTTATTAAAAGAAGCAAAACACTTAGAT
AGCAATACGGCATACAAAATTGAACAAATAGAAGATAAAGACTGGGAACGTGAGTGGATGGATAACTTCCACCCAATGCA
ATTTGGTAAGCGTTTATGGATTTGTCCAAGTTGGCGTGATGTGCCTGATGAAAATGCCGTCAATGTTATGCTTGACCCAG
GTTTAGCATTTGGTACAGGCACTCATCCTACAACCGCACTATGTTTAGAATGGCTAGATGGTCTTGATTTAAAAGATAAA
AGCGTCATCGATTTTGGTTGTGGATCTGGTATTTTAGCCATTGCAGCATTAAAACTTGGTGCGAAAAGTGCGGTGGGAAT
TGACATCGATCCACAAGCCATTCTGGCCAGTCGCAATAATGCTGAGCAAAATGGCGTGGCAGATCGCCTACAGCTGTTCT
TATCTGATGAAAAACCCTCTGATTTAAAAGCAGATGTCGTGGTGGCGAATATTCTTGCTGGCCCTCTCAAAGAACTTTAC
CCAATCATTAGCCAACTTGTTAAGCCGAATGGCGATCTTGGTTTATCGGGCATTTTAGAAACTCAAGCTCAATCGGTATG
CGATGCCTATACGCAAACATTTGCGTTAGAGCCAGTCGCGGCGAGAGAAGAATGGTGCCGAATTACGGGTAAGCTAAAAA
CGCTTTAA

Upstream 100 bases:

>100_bases
ACAATCATCATGCTCGCCACACTTGGCTCGACTTTACTGCCGAAACTTTTAAAAAAATCGGTATAATATGCCCCATTTTA
TGAAATAAAGGAAAAAACAA

Downstream 100 bases:

>100_bases
TTTCTTTTTGTCAATCAAAAAAAGTGTATTTTTTAAACAAATTTCACTTTGCAAAGCAAGGCAAAATGCGTATTATAGCC
AGCCTTGTCGGTTGTCGAGC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MAWIQIRLNSTNEKAEQMSDFLEEIGSVSVTFMDSQDTPIFEPLPGETRLWGNTDVIALFDAETDMAEIVRLLKEAKHLD
SNTAYKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTALCLEWLDGLDLKDK
SVIDFGCGSGILAIAALKLGAKSAVGIDIDPQAILASRNNAEQNGVADRLQLFLSDEKPSDLKADVVVANILAGPLKELY
PIISQLVKPNGDLGLSGILETQAQSVCDAYTQTFALEPVAAREEWCRITGKLKTL

Sequences:

>Translated_295_residues
MAWIQIRLNSTNEKAEQMSDFLEEIGSVSVTFMDSQDTPIFEPLPGETRLWGNTDVIALFDAETDMAEIVRLLKEAKHLD
SNTAYKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTALCLEWLDGLDLKDK
SVIDFGCGSGILAIAALKLGAKSAVGIDIDPQAILASRNNAEQNGVADRLQLFLSDEKPSDLKADVVVANILAGPLKELY
PIISQLVKPNGDLGLSGILETQAQSVCDAYTQTFALEPVAAREEWCRITGKLKTL
>Mature_294_residues
AWIQIRLNSTNEKAEQMSDFLEEIGSVSVTFMDSQDTPIFEPLPGETRLWGNTDVIALFDAETDMAEIVRLLKEAKHLDS
NTAYKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTALCLEWLDGLDLKDKS
VIDFGCGSGILAIAALKLGAKSAVGIDIDPQAILASRNNAEQNGVADRLQLFLSDEKPSDLKADVVVANILAGPLKELYP
IISQLVKPNGDLGLSGILETQAQSVCDAYTQTFALEPVAAREEWCRITGKLKTL

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=291, Percent_Identity=72.1649484536082, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32622; Mature: 32491

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWIQIRLNSTNEKAEQMSDFLEEIGSVSVTFMDSQDTPIFEPLPGETRLWGNTDVIALF
CEEEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEE
DAETDMAEIVRLLKEAKHLDSNTAYKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWRD
ECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCHHHCCEEEECCCCCC
VPDENAVNVMLDPGLAFGTGTHPTTALCLEWLDGLDLKDKSVIDFGCGSGILAIAALKLG
CCCCCCEEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHC
AKSAVGIDIDPQAILASRNNAEQNGVADRLQLFLSDEKPSDLKADVVVANILAGPLKELY
CCCEECCCCCCHHHEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
PIISQLVKPNGDLGLSGILETQAQSVCDAYTQTFALEPVAAREEWCRITGKLKTL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHCCC
>Mature Secondary Structure 
AWIQIRLNSTNEKAEQMSDFLEEIGSVSVTFMDSQDTPIFEPLPGETRLWGNTDVIALF
EEEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEE
DAETDMAEIVRLLKEAKHLDSNTAYKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWRD
ECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCHHHCCEEEECCCCCC
VPDENAVNVMLDPGLAFGTGTHPTTALCLEWLDGLDLKDKSVIDFGCGSGILAIAALKLG
CCCCCCEEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHC
AKSAVGIDIDPQAILASRNNAEQNGVADRLQLFLSDEKPSDLKADVVVANILAGPLKELY
CCCEECCCCCCHHHEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
PIISQLVKPNGDLGLSGILETQAQSVCDAYTQTFALEPVAAREEWCRITGKLKTL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]