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The map label for this gene is menC [H]

Identifier: 148828147

GI number: 148828147

Start: 1557543

End: 1558532

Strand: Direct

Name: menC [H]

Synonym: CGSHiGG_08425

Alternate gene names: 148828147

Gene position: 1557543-1558532 (Clockwise)

Preceding gene: 148828146

Following gene: 148828148

Centisome position: 82.53

GC content: 41.31

Gene sequence:

>990_bases
ATGGCTGAAAAATCATTTAATCTTTACCGTTATTCTATCCCCGTTGATAGCCAACTTATTCTGCGTGATCGTTTTTTAAA
ACGCCGTGAAGGCTTAATCGTAAGAGTGAGTTGCAGCCGAGACGGTTGGGGAGAAATCGCTCCGTTACCTGGTTTTAGCG
AAGAAACCTTAGACCAAGCTCAAGAACAAGCAATTGAATGGCTAACGACATGGTGCAATGCAAGCTGTGACGCACCTCGC
GTCCCATTAGATGGCACCTATCCTTCCGTTGCTTTTGGTATCAGTTGCGCAATGGATGAAATGAAAGGTTATTTACAAGC
TGAAGGCAATTATCATACAGCACCACTTTGTTATGGCGATCCAGATGAATTGTACGCCAAACTTGCGAGCATGGAAGGCG
AAAAAGTAGCAAAGATGAAAGTGGGCATATACGAAGCCAATCGCGATGGATTAATTGCCGATATGTTTTTAGAAGCGATT
CCTGATTTACAATTACGGCTTGATGCAAACCGCCATTGGTCGTTAGAAAAAGCCTTACAATTTGCCGCTAAAGTCAAACC
GCAACATAGAAAACGTATTCAATTTTTAGAAGAACCTTGTAAAACACAAGAACTCAGCCGTGAATTTGCAGCTCAAACCG
ATATTGCAATTGCATGGGATGAATCCGTGCGAGAGCCTAATTTTTGTCTAGAAAAAGAACCGCACTTATCGGCTATCGTC
ATCAAACCCACTTTAATTGGTTCAATTCAACGTTGTACTGAGCTCATTAACCAAGCACATTCGTTAGGTCTAAAAGCGGT
TATAAGTTCAAGTATCGAAAGCAGTTTAGGGCTCTCTCAGCTCGCACGAATTGCACAACAATACACCCCGAATGTGACTC
CAGGCTTAGATACTTTAGATTTGATGGAATATCAAGTACTACGTGCTTGGCCTAGTTCTGATTTACCTATTGTTGATTTA
GAATCTGAATTTATCACTAAAATTATCTGA

Upstream 100 bases:

>100_bases
CAGACTTCAGCAAATTCAGACGTAACCCTTAATTTATCGTTCTAAAGTGCGGTTAAAAATCTTCGTGAATTTTGACCGCA
CTTTTGTATTGGGAGCAAGC

Downstream 100 bases:

>100_bases
TTCGACCACCAAAAATCGAAAAACCAGTATAATGCGCTACACAAAAAGGATTAAAAATGTCGCAAACACACAGAATTTTG
CTGTTAAATGGCCCGAACTT

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MAEKSFNLYRYSIPVDSQLILRDRFLKRREGLIVRVSCSRDGWGEIAPLPGFSEETLDQAQEQAIEWLTTWCNASCDAPR
VPLDGTYPSVAFGISCAMDEMKGYLQAEGNYHTAPLCYGDPDELYAKLASMEGEKVAKMKVGIYEANRDGLIADMFLEAI
PDLQLRLDANRHWSLEKALQFAAKVKPQHRKRIQFLEEPCKTQELSREFAAQTDIAIAWDESVREPNFCLEKEPHLSAIV
IKPTLIGSIQRCTELINQAHSLGLKAVISSSIESSLGLSQLARIAQQYTPNVTPGLDTLDLMEYQVLRAWPSSDLPIVDL
ESEFITKII

Sequences:

>Translated_329_residues
MAEKSFNLYRYSIPVDSQLILRDRFLKRREGLIVRVSCSRDGWGEIAPLPGFSEETLDQAQEQAIEWLTTWCNASCDAPR
VPLDGTYPSVAFGISCAMDEMKGYLQAEGNYHTAPLCYGDPDELYAKLASMEGEKVAKMKVGIYEANRDGLIADMFLEAI
PDLQLRLDANRHWSLEKALQFAAKVKPQHRKRIQFLEEPCKTQELSREFAAQTDIAIAWDESVREPNFCLEKEPHLSAIV
IKPTLIGSIQRCTELINQAHSLGLKAVISSSIESSLGLSQLARIAQQYTPNVTPGLDTLDLMEYQVLRAWPSSDLPIVDL
ESEFITKII
>Mature_328_residues
AEKSFNLYRYSIPVDSQLILRDRFLKRREGLIVRVSCSRDGWGEIAPLPGFSEETLDQAQEQAIEWLTTWCNASCDAPRV
PLDGTYPSVAFGISCAMDEMKGYLQAEGNYHTAPLCYGDPDELYAKLASMEGEKVAKMKVGIYEANRDGLIADMFLEAIP
DLQLRLDANRHWSLEKALQFAAKVKPQHRKRIQFLEEPCKTQELSREFAAQTDIAIAWDESVREPNFCLEKEPHLSAIVI
KPTLIGSIQRCTELINQAHSLGLKAVISSSIESSLGLSQLARIAQQYTPNVTPGLDTLDLMEYQVLRAWPSSDLPIVDLE
SEFITKII

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=320, Percent_Identity=56.25, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 36999; Mature: 36867

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKSFNLYRYSIPVDSQLILRDRFLKRREGLIVRVSCSRDGWGEIAPLPGFSEETLDQA
CCCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
QEQAIEWLTTWCNASCDAPRVPLDGTYPSVAFGISCAMDEMKGYLQAEGNYHTAPLCYGD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCC
PDELYAKLASMEGEKVAKMKVGIYEANRDGLIADMFLEAIPDLQLRLDANRHWSLEKALQ
HHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
FAAKVKPQHRKRIQFLEEPCKTQELSREFAAQTDIAIAWDESVREPNFCLEKEPHLSAIV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCEEEE
IKPTLIGSIQRCTELINQAHSLGLKAVISSSIESSLGLSQLARIAQQYTPNVTPGLDTLD
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHH
LMEYQVLRAWPSSDLPIVDLESEFITKII
HHHHHHHHHCCCCCCCEEECCHHHHHHCC
>Mature Secondary Structure 
AEKSFNLYRYSIPVDSQLILRDRFLKRREGLIVRVSCSRDGWGEIAPLPGFSEETLDQA
CCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
QEQAIEWLTTWCNASCDAPRVPLDGTYPSVAFGISCAMDEMKGYLQAEGNYHTAPLCYGD
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCC
PDELYAKLASMEGEKVAKMKVGIYEANRDGLIADMFLEAIPDLQLRLDANRHWSLEKALQ
HHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
FAAKVKPQHRKRIQFLEEPCKTQELSREFAAQTDIAIAWDESVREPNFCLEKEPHLSAIV
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCEEEE
IKPTLIGSIQRCTELINQAHSLGLKAVISSSIESSLGLSQLARIAQQYTPNVTPGLDTLD
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHH
LMEYQVLRAWPSSDLPIVDLESEFITKII
HHHHHHHHHCCCCCCCEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]