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The map label for this gene is secA [H]

Identifier: 148828087

GI number: 148828087

Start: 1492908

End: 1495613

Strand: Direct

Name: secA [H]

Synonym: CGSHiGG_08105

Alternate gene names: 148828087

Gene position: 1492908-1495613 (Clockwise)

Preceding gene: 148828086

Following gene: 148828088

Centisome position: 79.11

GC content: 40.39

Gene sequence:

>2706_bases
ATGAGCATTTTAACAAGAATTTTTGGTAGTCGTAATGAACGCGTTTTACGTAAATTAAAAAAACAAGTCGTAAAAATTAA
TAAAATGGAGCCTGCTTTTGAGGCATTAAGTGATGATGAATTAAAAGCAAAAACACAAGAGTTTCGTGATCGTTTAAGTG
GTGGCGAAACTTTGCAACAAATTTTACCAGAAGCATTCGCAACGGTACGCGAAGCAAGTAAGCGTGTGCTTGGTATGCGC
CATTTTGATGTGCAGCTTATCGGTGGGATGGTATTGACTAACCGCTGTATCGCAGAAATGCGTACTGGTGAAGGTAAAAC
ATTAACGGCGACTTTGCCTTGTTATTTAATCGCACTTGAAGGTAAAGGCGTTCATGTTGTCACGGTGAATGATTATCTTG
CTCGCCGAGATGCAGAAACCAACCGTCCGTTATTTGAATTTTTGGGTATGAGCGTAGGCGTCAATATTCCTGGGTTATCG
CCAGAAGAAAAACGTGAAGCTTATGCGGCAGATATTACTTATGCAACCAATAGTGAACTTGGTTTTGATTATTTACGTGA
CAACTTAGCCCACTCAAAAGAAGAGCGTTTCCAACGTACTTTAGGCTATGCGTTGGTGGATGAAGTGGATTCTATCTTAA
TCGATGAAGCACGTACACCATTGATTATTTCAGGTCAGGCAGAAAAAAGTTCAGAGCTTTATATTGCGGTAAATAAATTG
ATCCCAAGTTTAATTAAACAAGAAAAAGAAGATACGGAAGAATATCAAGGAGAGGGCGATTTCACTTTAGATTTGAAATC
TAAACAAGCACATTTAACCGAACGTGGTCAAGAAAAAGTGGAAGATTGGTTAATTGCACAAGGTTTAATGCCTGAGGGGG
ACTCTTTGTATTCTCCTAGTCGAATTGTATTGCTTCATCACGTTATGGCTGCATTGCGTGCGCACACATTGTTTGAAAAA
GATGTCGATTACATTGTGAAAGACGGTGAAATCGTGATTGTTGATGAACACACTGGTCGTACAATGGCGGGGCGTCGTTG
GTCAGATGGTTTGCACCAAGCCATTGAGGCAAAAGAAGGGGTGGATATTAAGAGCGAAAACCAAACTGTTGCGTCAATTT
CTTACCAAAACTACTTCCGTTTATATGAACGTCTTGCGGGTATGACGGGGACTGCGGATACCGAAGCATTTGAGTTCCAA
CAAATTTATGGCTTGGAAACTGTTGTAATTCCAACAAATCGTCCAATGATTCGTGATGATCGCACTGATGTGATGTTTGA
AAATGAACAATATAAATTTAATGCGATTATTGAAGACATTAAAGATTGTGTAGAACGCCAGCAACCAGTATTAGTGGGGA
CGATTTCAGTCGAAAAATCAGAAGAATTATCTAAAGCGTTAGATAAAGCAGGTATAAAACACAATGTGTTGAATGCGAAA
TTCCACCAACAAGAAGCGGAAATCGTGGCAGAAGCAGGATTTCCTAGTGCAGTGACTATCGCAACGAATATGGCGGGTCG
AGGTACCGATATTATTCTTGGCGGTAACTGGAAAGCGCAGGCTGCCAAATTAGAAAATCCAACTCAAGAACAAATTGAAG
CCCTTAAAGCAGAGTGGGAGAAAAACCACGAAATTGTAATGAAAGCGGGTGGGTTGCATATTATCGGTACAGAGCGTCAC
GAATCTCGTCGTATTGATAACCAGTTGCGCGGTCGTTCTGGGCGTCAAGGTGACCCCGGTTCTTCTCGTTTCTATCTTTC
TTTAGAAGATGGTTTAATGCGCATTTATTTGAATGAGGGTAAGCGCAATTTAATGCGTAAAGCGTTCACGGTAGCAGGCG
AGGCAATGGAGTCGAAAATGTTGGCGAAAGTGATTGCATCTGCTCAAGCAAAAGTTGAGGCGTTCCATTTCGATGGCCGT
AAAAACCTACTTGAATATGATGATGTGGCAAATGACCAACGTCACGCGATTTATGAGCAACGCAATTATTTGCTTGATAA
TGATGATATTTCTGAAACTATCAACGCTATTCGCCACGATGTGTTTAATGGTGTGATTGATCAATATATTCCACCACAAT
CTTTGGAAGAACAATGGGATATTAAAGGGCTTGAAGAACGTTTATCTCAAGAATTTGGTATGGAATTACCGATTTCTAAT
TGGTTAGAAGAAGATAATAATCTTCACGAAGAAAGTTTGCGCGAACGCATTGTGGAAATTGCAGAAAAGGAATACAAAGA
AAAAGAGGCTTTGGTTGGCGAAGATGCTATGCACCATTTTGAAAAAGGTGTTATGTTGCAAACCTTAGATGAACTTTGGA
AAGAACACTTAGCTTCGATGGATTATTTACGCCAAGGTATTCATTTACGCGGCTATGCACAAAAAGATCCAAAACAAGAA
TATAAAAAAGAATCTTTCCGCATGTTTACGGAAATGCTAGATTCCTTAAAACACCACGTTATCATGACTTTAACCCGTGT
ACGTGTGCGTACTCAAGAAGAAATGGAAGAAGCTGAACTTGCTCGTCAGGAGATGGCTACTCGTATCAATCAAAATAATT
TACCTGTGGATGAAAATAGTCAGACAACTCAAAATTCAGAGACTGAAGATTATTCAGATCGTCGCATTGGTCGCAACGAG
CCTTGTCCTTGTGGGTCGGGTAAAAAATATAAGCATTGTCACGGCAGTCGTGTGGCACGCCAGTAA

Upstream 100 bases:

>100_bases
TTGCTATTGAAATAGCGATATTTTAAAAAATTATTGTGCATGAAATAAAGTATTTCATAAGCATTTAACTATTTAACTTA
TATATTTAAAAAGAGAAATT

Downstream 100 bases:

>100_bases
TGAACAATCAAAGTGCGGTGATTTTTCACCGCACTTTTTTCATACCTCTACATTGGATAGAAAAATGGATAAAAAAATTA
TACAAGTTGCTGCGGGGATT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 901; Mature: 900

Protein sequence:

>901_residues
MSILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQILPEAFATVREASKRVLGMR
HFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALEGKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLS
PEEKREAYAADITYATNSELGFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAEKSSELYIAVNKL
IPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPSRIVLLHHVMAALRAHTLFEK
DVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVDIKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQ
QIYGLETVVIPTNRPMIRDDRTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAK
FHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWEKNHEIVMKAGGLHIIGTERH
ESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEGKRNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGR
KNLLEYDDVANDQRHAIYEQRNYLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISN
WLEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMHHFEKGVMLQTLDELWKEHLASMDYLRQGIHLRGYAQKDPKQE
YKKESFRMFTEMLDSLKHHVIMTLTRVRVRTQEEMEEAELARQEMATRINQNNLPVDENSQTTQNSETEDYSDRRIGRNE
PCPCGSGKKYKHCHGSRVARQ

Sequences:

>Translated_901_residues
MSILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQILPEAFATVREASKRVLGMR
HFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALEGKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLS
PEEKREAYAADITYATNSELGFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAEKSSELYIAVNKL
IPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPSRIVLLHHVMAALRAHTLFEK
DVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVDIKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQ
QIYGLETVVIPTNRPMIRDDRTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAK
FHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWEKNHEIVMKAGGLHIIGTERH
ESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEGKRNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGR
KNLLEYDDVANDQRHAIYEQRNYLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISN
WLEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMHHFEKGVMLQTLDELWKEHLASMDYLRQGIHLRGYAQKDPKQE
YKKESFRMFTEMLDSLKHHVIMTLTRVRVRTQEEMEEAELARQEMATRINQNNLPVDENSQTTQNSETEDYSDRRIGRNE
PCPCGSGKKYKHCHGSRVARQ
>Mature_900_residues
SILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQILPEAFATVREASKRVLGMRH
FDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALEGKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLSP
EEKREAYAADITYATNSELGFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAEKSSELYIAVNKLI
PSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPSRIVLLHHVMAALRAHTLFEKD
VDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVDIKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQQ
IYGLETVVIPTNRPMIRDDRTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAKF
HQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWEKNHEIVMKAGGLHIIGTERHE
SRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEGKRNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGRK
NLLEYDDVANDQRHAIYEQRNYLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISNW
LEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMHHFEKGVMLQTLDELWKEHLASMDYLRQGIHLRGYAQKDPKQEY
KKESFRMFTEMLDSLKHHVIMTLTRVRVRTQEEMEEAELARQEMATRINQNNLPVDENSQTTQNSETEDYSDRRIGRNEP
CPCGSGKKYKHCHGSRVARQ

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=896, Percent_Identity=68.4151785714286, Blast_Score=1280, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 102780; Mature: 102649

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQ
CCHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHH
ILPEAFATVREASKRVLGMRHFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECEEEEEEC
GKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLSPEEKREAYAADITYATNSEL
CCCEEEEEECHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCC
GFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAEKSSELYIAVNKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEHHHH
IPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPS
HHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
RIVLLHHVMAALRAHTLFEKDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEG
HHHHHHHHHHHHHHHHHHHHCHHHEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCC
VDIKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQQIYGLETVVIPTNRPMIRDD
CCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCC
RTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAK
CCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHCHH
FHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWE
HHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCHHHHHCCCCCHHHHHHHHHHHC
KNHEIVMKAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEG
CCCEEEEEECCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEHHH
KRNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGRKNLLEYDDVANDQRHAIYEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCCCHHHHHHHH
RNYLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISN
HCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCCCCHHH
WLEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMHHFEKGVMLQTLDELWKEHLASM
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHHHH
DYLRQGIHLRGYAQKDPKQEYKKESFRMFTEMLDSLKHHVIMTLTRVRVRTQEEMEEAEL
HHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQEMATRINQNNLPVDENSQTTQNSETEDYSDRRIGRNEPCPCGSGKKYKHCHGSRVAR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHCC
Q
C
>Mature Secondary Structure 
SILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQ
CHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHHHHH
ILPEAFATVREASKRVLGMRHFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECEEEEEEC
GKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLSPEEKREAYAADITYATNSEL
CCCEEEEEECHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHEEEEECCCCC
GFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAEKSSELYIAVNKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEHHHH
IPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPS
HHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
RIVLLHHVMAALRAHTLFEKDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEG
HHHHHHHHHHHHHHHHHHHHCHHHEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCC
VDIKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQQIYGLETVVIPTNRPMIRDD
CCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCC
RTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAK
CCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHCHH
FHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWE
HHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCHHHHHCCCCCHHHHHHHHHHHC
KNHEIVMKAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEG
CCCEEEEEECCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEHHH
KRNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGRKNLLEYDDVANDQRHAIYEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCCCHHHHHHHH
RNYLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISN
HCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCCCCCHHH
WLEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMHHFEKGVMLQTLDELWKEHLASM
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHHHH
DYLRQGIHLRGYAQKDPKQEYKKESFRMFTEMLDSLKHHVIMTLTRVRVRTQEEMEEAEL
HHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQEMATRINQNNLPVDENSQTTQNSETEDYSDRRIGRNEPCPCGSGKKYKHCHGSRVAR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA