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The map label for this gene is rppH [H]

Identifier: 148828081

GI number: 148828081

Start: 1488479

End: 1489069

Strand: Direct

Name: rppH [H]

Synonym: CGSHiGG_08065

Alternate gene names: 148828081

Gene position: 1488479-1489069 (Clockwise)

Preceding gene: 148828080

Following gene: 148828082

Centisome position: 78.87

GC content: 40.1

Gene sequence:

>591_bases
GTGATCGATTTTGATGGCTACCGTCCAAATGTGGGTATTGTGATTTGTAATCGCAAAGGGCAAGTGCTTTGGGCGAAGCG
TTGTGGGCAAAATTCGTGGCAGTTTCCGCAAGGTGGCATTAATGATAATGAAAGTGCCGAGCAAGCGATGTATCGCGAAC
TACACGAGGAAGTTGGTTTACAACCTAAAGATGTGCGTCTGTTATATGTTTCTAAACATTGGTTACGCTATAAATTGCCA
AAGCGTTTATTGCGTTATGACAGCAAGCCGATGTGTATTGGGCAGAAACAACGCTGGTTTTTGCTACAGCTTGTTAGCGA
TGAAAAAAACATCAATATGCAAACAACTAAATCGCCAGAATTTGACGGGTGGCGTTGGGTAAGTTTTTGGTATCCTGTTC
GTCAAGTTGTGTCTTTTAAGCGAGATGTTTATCGAAAGGTAATGAAAGAGTTTGCTTCGATACTATTTACGGACAATCCA
CTAATATTTTCCACATCTCGTGAAGCAAATTCACAGCATTATTCGGCAAACAAAAAATATTCTCAGACAAAATACACGAA
ACGCCATTTTTATAAATCAAGAGGCCAATAA

Upstream 100 bases:

>100_bases
ATATGATTATTTTGTCATAATGTCCTTTGGTTGATAAAAGCACTGATTTATGAAACAATCTTGAGCTATTTTTATAGGAA
AAATTTAAGGTAAAACGATA

Downstream 100 bases:

>100_bases
TGTTCACTTTTATTCTTCTTTGTTTACTTGTTGGCGCATTAGCGGGTTTTCTTGCAGGATTATTTGGTATCGGCGGTGGG
TTAGTAATTGTGCCAACGTT

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MIDFDGYRPNVGIVICNRKGQVLWAKRCGQNSWQFPQGGINDNESAEQAMYRELHEEVGLQPKDVRLLYVSKHWLRYKLP
KRLLRYDSKPMCIGQKQRWFLLQLVSDEKNINMQTTKSPEFDGWRWVSFWYPVRQVVSFKRDVYRKVMKEFASILFTDNP
LIFSTSREANSQHYSANKKYSQTKYTKRHFYKSRGQ

Sequences:

>Translated_196_residues
MIDFDGYRPNVGIVICNRKGQVLWAKRCGQNSWQFPQGGINDNESAEQAMYRELHEEVGLQPKDVRLLYVSKHWLRYKLP
KRLLRYDSKPMCIGQKQRWFLLQLVSDEKNINMQTTKSPEFDGWRWVSFWYPVRQVVSFKRDVYRKVMKEFASILFTDNP
LIFSTSREANSQHYSANKKYSQTKYTKRHFYKSRGQ
>Mature_196_residues
MIDFDGYRPNVGIVICNRKGQVLWAKRCGQNSWQFPQGGINDNESAEQAMYRELHEEVGLQPKDVRLLYVSKHWLRYKLP
KRLLRYDSKPMCIGQKQRWFLLQLVSDEKNINMQTTKSPEFDGWRWVSFWYPVRQVVSFKRDVYRKVMKEFASILFTDNP
LIFSTSREANSQHYSANKKYSQTKYTKRHFYKSRGQ

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=174, Percent_Identity=72.4137931034483, Blast_Score=269, Evalue=8e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 23506; Mature: 23506

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFDGYRPNVGIVICNRKGQVLWAKRCGQNSWQFPQGGINDNESAEQAMYRELHEEVGL
CCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
QPKDVRLLYVSKHWLRYKLPKRLLRYDSKPMCIGQKQRWFLLQLVSDEKNINMQTTKSPE
CCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCCCCEEECCCCC
FDGWRWVSFWYPVRQVVSFKRDVYRKVMKEFASILFTDNPLIFSTSREANSQHYSANKKY
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCCCCCCH
SQTKYTKRHFYKSRGQ
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIDFDGYRPNVGIVICNRKGQVLWAKRCGQNSWQFPQGGINDNESAEQAMYRELHEEVGL
CCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
QPKDVRLLYVSKHWLRYKLPKRLLRYDSKPMCIGQKQRWFLLQLVSDEKNINMQTTKSPE
CCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCCCCEEECCCCC
FDGWRWVSFWYPVRQVVSFKRDVYRKVMKEFASILFTDNPLIFSTSREANSQHYSANKKY
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCCCCCCH
SQTKYTKRHFYKSRGQ
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA