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The map label for this gene is dipZ [H]

Identifier: 148828065

GI number: 148828065

Start: 1468507

End: 1470246

Strand: Direct

Name: dipZ [H]

Synonym: CGSHiGG_07975

Alternate gene names: 148828065

Gene position: 1468507-1470246 (Clockwise)

Preceding gene: 148828062

Following gene: 148828066

Centisome position: 77.81

GC content: 37.82

Gene sequence:

>1740_bases
ATGAAAAAACTCTTTCTTTTTTTTACGCTGATTTTCACCGCTTTTGCGGCTAATTCAGGTTTATTCGATAAAAAACAAAC
CTTTTTAAAAGTAGATGATGCTTTTGCTTTTTCTGCTACTTTATCTACAGATAAAAGCCAGTTACAAGCCCATTGGGATA
TTGCCGATGGCTATTATTTGTATCAAGATAAAATTAGTGCTGAGTTAGTCGGTAAATCAAATCCTCTCTCTTTACATACC
CAACAGGCGGCGGAATTACATCAAGATCCTTATTTTGGCGAAGTAAAAGTTTTTACTCACTCAATTGATGGCATATTTAG
GGGCACATTTAATAATGCTGATGATAAGGTTGAAATCACTTATCAAGGATGTACCGAAGGTTTTTGCTATCCGCCTGAAA
CTAAAGTATTACGAATTGGGGATTTAGCCGTTTCTCAAGAGCAAATTGTCGAAAAAACAGTTGAAAAAAATACCGCACTT
TTATCTGAACAAGATCGTTTAGCTGATGGTTTATTCCATAGTAAATGGGCAATTTTTGGTTTCTTTGTATTAGGATTGGG
ACTGGCTTTTACGCCTTGCGTATTGCCAATGTTACCGTTGCTTTCTGCTATTGTTATCGGTCAGCAACAACGTCCAAATA
TGATGCGAGCGTTTAGTTTAGCTTTTCTTTATGTTCAAGGCATGGCTCTGACTTACACTTTGTTAGGGCTTGCAGTGGCA
GCCATCGGTTTACCGTTCCAAATCGCCTTGCAACATCCTTATGTGATGATCGGGCTTTCTATTTTATTTGTTGTGCTTGC
CCTTTCAATGTTTGGCTTATTTACTATTCAATTGCCAAATAGCTTACAAAATAAACTCAATACATGGAGCCAAAAACAAA
CCTCGGGTGCTTTTGGCGGAGCCTTTGCAATGGGAATGATTGCTGGGCTGGTGGCATCGCCTTGTACATCTGCGCCACTT
TCTGGTGCTTTACTTTATGTGGCACAAAGTGGCGATTTATTTACAGGCGCAGTAACCCTTTATTTGCTCGCACTTGGTAT
GGGCGTGCCGCTAATGTTAATCACATTGTTTGGTAATAAAATTTTGCCCAAATCAGGTGAGTGGATGAATACCGTAAAAC
AAACATTCGGCTTTGTGATGTTAGCGTTACCTGTATTTTTACTTTCTCGTATTTTGCCTGAAGTATGGGAGTCACGCTTA
TGGGCTGGGTTAGCGACAGTATTTTTTATTTGGTTTGCGTTGCAGATGTCTAAGAACGGTTTTGGCTATGCTATTAAAAT
TATTAGTTTTGCGTTGGCTATGGTTACTGTACAACCCCTGCAAAATTGGATTTGGCAAACTCAAACTACAACACAAAGTG
CGGTAGAAAATATGCCTGTTTCTCAAGTTAAATTTAAGCAAATTAAAAATACTGAAGAACTTGACCGCACTTTAGCGGAA
AATCCGCATTCAATTGCTATGTTGGATTTATACGCGGATTGGTGTGTTGCTTGTAAAGAATTTGAAAAGCTGACGTTTTC
AGATCCACAAGTGCAACAGCAATTTCAAAATATCTTATTGTTACAAGTGAATATGACAAAGAATAGCCCAGAAAATAAAG
CATTAATGGAACGCTTTAATGTGATGGGATTGCCTACGATTTTATTTTTTGATCAGCAAAATAATGAAATTAAAGGAAGT
AGAGTAACGGGCTTTATGGATGCTGATGCTTTTTCTAATTGGATTGAAAAGCTACTTTAG

Upstream 100 bases:

>100_bases
TTTTACCTGATTTTCCTTTTTGTGATCTAAATCATAGTTTTAGGTATTCAAATTTCTTTGTGATAGAATTTCGAGCATCT
ATATTTTTACACTCAATTCT

Downstream 100 bases:

>100_bases
TTATTTTTTACTTTTGGTAAAAAGTATTTTTCAATTTTAATTATTGTTTAACTACCCGTTAAAGATTAATATGACGCCGT
TTTAATTCATCTTTAAACAA

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MKKLFLFFTLIFTAFAANSGLFDKKQTFLKVDDAFAFSATLSTDKSQLQAHWDIADGYYLYQDKISAELVGKSNPLSLHT
QQAAELHQDPYFGEVKVFTHSIDGIFRGTFNNADDKVEITYQGCTEGFCYPPETKVLRIGDLAVSQEQIVEKTVEKNTAL
LSEQDRLADGLFHSKWAIFGFFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAFLYVQGMALTYTLLGLAVA
AIGLPFQIALQHPYVMIGLSILFVVLALSMFGLFTIQLPNSLQNKLNTWSQKQTSGAFGGAFAMGMIAGLVASPCTSAPL
SGALLYVAQSGDLFTGAVTLYLLALGMGVPLMLITLFGNKILPKSGEWMNTVKQTFGFVMLALPVFLLSRILPEVWESRL
WAGLATVFFIWFALQMSKNGFGYAIKIISFALAMVTVQPLQNWIWQTQTTTQSAVENMPVSQVKFKQIKNTEELDRTLAE
NPHSIAMLDLYADWCVACKEFEKLTFSDPQVQQQFQNILLLQVNMTKNSPENKALMERFNVMGLPTILFFDQQNNEIKGS
RVTGFMDADAFSNWIEKLL

Sequences:

>Translated_579_residues
MKKLFLFFTLIFTAFAANSGLFDKKQTFLKVDDAFAFSATLSTDKSQLQAHWDIADGYYLYQDKISAELVGKSNPLSLHT
QQAAELHQDPYFGEVKVFTHSIDGIFRGTFNNADDKVEITYQGCTEGFCYPPETKVLRIGDLAVSQEQIVEKTVEKNTAL
LSEQDRLADGLFHSKWAIFGFFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAFLYVQGMALTYTLLGLAVA
AIGLPFQIALQHPYVMIGLSILFVVLALSMFGLFTIQLPNSLQNKLNTWSQKQTSGAFGGAFAMGMIAGLVASPCTSAPL
SGALLYVAQSGDLFTGAVTLYLLALGMGVPLMLITLFGNKILPKSGEWMNTVKQTFGFVMLALPVFLLSRILPEVWESRL
WAGLATVFFIWFALQMSKNGFGYAIKIISFALAMVTVQPLQNWIWQTQTTTQSAVENMPVSQVKFKQIKNTEELDRTLAE
NPHSIAMLDLYADWCVACKEFEKLTFSDPQVQQQFQNILLLQVNMTKNSPENKALMERFNVMGLPTILFFDQQNNEIKGS
RVTGFMDADAFSNWIEKLL
>Mature_579_residues
MKKLFLFFTLIFTAFAANSGLFDKKQTFLKVDDAFAFSATLSTDKSQLQAHWDIADGYYLYQDKISAELVGKSNPLSLHT
QQAAELHQDPYFGEVKVFTHSIDGIFRGTFNNADDKVEITYQGCTEGFCYPPETKVLRIGDLAVSQEQIVEKTVEKNTAL
LSEQDRLADGLFHSKWAIFGFFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAFLYVQGMALTYTLLGLAVA
AIGLPFQIALQHPYVMIGLSILFVVLALSMFGLFTIQLPNSLQNKLNTWSQKQTSGAFGGAFAMGMIAGLVASPCTSAPL
SGALLYVAQSGDLFTGAVTLYLLALGMGVPLMLITLFGNKILPKSGEWMNTVKQTFGFVMLALPVFLLSRILPEVWESRL
WAGLATVFFIWFALQMSKNGFGYAIKIISFALAMVTVQPLQNWIWQTQTTTQSAVENMPVSQVKFKQIKNTEELDRTLAE
NPHSIAMLDLYADWCVACKEFEKLTFSDPQVQQQFQNILLLQVNMTKNSPENKALMERFNVMGLPTILFFDQQNNEIKGS
RVTGFMDADAFSNWIEKLL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=578, Percent_Identity=47.2318339100346, Blast_Score=516, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 64455; Mature: 64455

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFLFFTLIFTAFAANSGLFDKKQTFLKVDDAFAFSATLSTDKSQLQAHWDIADGYYL
CCHHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCCEEEEECCCCHHHHHEEEECCCCEEE
YQDKISAELVGKSNPLSLHTQQAAELHQDPYFGEVKVFTHSIDGIFRGTFNNADDKVEIT
EECCCCHHCCCCCCCCEEEHHHHHHHHCCCCCCEEEEEEEHHCHHEECCCCCCCCEEEEE
YQGCTEGFCYPPETKVLRIGDLAVSQEQIVEKTVEKNTALLSEQDRLADGLFHSKWAIFG
EECCCCCCCCCCCCCEEEECCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAFLYVQGMALTYTLLGLAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGLPFQIALQHPYVMIGLSILFVVLALSMFGLFTIQLPNSLQNKLNTWSQKQTSGAFGG
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHCCCCCHH
AFAMGMIAGLVASPCTSAPLSGALLYVAQSGDLFTGAVTLYLLALGMGVPLMLITLFGNK
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCC
ILPKSGEWMNTVKQTFGFVMLALPVFLLSRILPEVWESRLWAGLATVFFIWFALQMSKNG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FGYAIKIISFALAMVTVQPLQNWIWQTQTTTQSAVENMPVSQVKFKQIKNTEELDRTLAE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHC
NPHSIAMLDLYADWCVACKEFEKLTFSDPQVQQQFQNILLLQVNMTKNSPENKALMERFN
CCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHC
VMGLPTILFFDQQNNEIKGSRVTGFMDADAFSNWIEKLL
CCCCCEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHC
>Mature Secondary Structure
MKKLFLFFTLIFTAFAANSGLFDKKQTFLKVDDAFAFSATLSTDKSQLQAHWDIADGYYL
CCHHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCCEEEEECCCCHHHHHEEEECCCCEEE
YQDKISAELVGKSNPLSLHTQQAAELHQDPYFGEVKVFTHSIDGIFRGTFNNADDKVEIT
EECCCCHHCCCCCCCCEEEHHHHHHHHCCCCCCEEEEEEEHHCHHEECCCCCCCCEEEEE
YQGCTEGFCYPPETKVLRIGDLAVSQEQIVEKTVEKNTALLSEQDRLADGLFHSKWAIFG
EECCCCCCCCCCCCCEEEECCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVLGLGLAFTPCVLPMLPLLSAIVIGQQQRPNMMRAFSLAFLYVQGMALTYTLLGLAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGLPFQIALQHPYVMIGLSILFVVLALSMFGLFTIQLPNSLQNKLNTWSQKQTSGAFGG
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHCCCCCHH
AFAMGMIAGLVASPCTSAPLSGALLYVAQSGDLFTGAVTLYLLALGMGVPLMLITLFGNK
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCC
ILPKSGEWMNTVKQTFGFVMLALPVFLLSRILPEVWESRLWAGLATVFFIWFALQMSKNG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FGYAIKIISFALAMVTVQPLQNWIWQTQTTTQSAVENMPVSQVKFKQIKNTEELDRTLAE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHC
NPHSIAMLDLYADWCVACKEFEKLTFSDPQVQQQFQNILLLQVNMTKNSPENKALMERFN
CCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHC
VMGLPTILFFDQQNNEIKGSRVTGFMDADAFSNWIEKLL
CCCCCEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA