Click here to switch to the map view.

The map label for this gene is secG [H]

Identifier: 148827642

GI number: 148827642

Start: 991952

End: 993622

Strand: Reverse

Name: secG [H]

Synonym: CGSHiGG_05455

Alternate gene names: 148827642

Gene position: 993622-991952 (Counterclockwise)

Preceding gene: 148827643

Following gene: 148827636

Centisome position: 52.65

GC content: 41.83

Gene sequence:

>1671_bases
ATGAAGTTATTTTTAACCCAATCAGCTAATGTAGGCGATGCGAAAGCCTATTTATTACATGAAGTTTTTCGAGCAGCTGC
ACAAAAAGCAAATGTCTCTATTGTAGAAACACCAGCCGAAGCAGATCTTGTTCTTGTATTTGGTTCTGTCTTACCAAATA
ACCCTGAGTTAGTCGGTAAAAAAGTCTTTATTATCGGCGAAGCTATCGCCATGATTTCTCCTGAAGTCACGCTGGCAAAT
GCTTTAGCCAATGGGGCTGATTATGTTGCTCCGAAAAGTACGGTGAGTTTTACAGGTGTTTCTGGTGTAAAAAATATTGT
TGCGGTAACGGCTTGTCCAACTGGCGTTGCACATACGTTTATGTCAGCCGAAGCGATTGAAGCCTATGCGAAAAAGCAAG
GTTGGAATATAAAAGTTGAAACCCGTGGTCAAGTTGGGGCTGGCAATGAAATTACTGTGGAAGAAGTCGCAGCGGCTGAT
TTGGTATTTGTTGCAGCAGATATTGATGTGCCTTTAGATAAATTTAAAGGTAAGCCAATGTACCGCACTTCAACAGGCTT
AGCCTTGAAGAAAACCGATCAAGAATTTGATAAAGCATTTAAAGAGGCCAAAATTTTTGATGGTGGAAATAATGCGGGAA
CGAAAGAAGAAAGCCGTGAGAAAAAAGGTGTGTACAAACACTTAATGACTGGTGTTTCTCATATGTTACCGTTAGTGGTT
GCTGGTGGATTGTTGATCGCGATTTCCTTTATGTTCAGTTTTAATGTAATTGAAAATACAGGAGTTTTTCAAGATCTTCC
TAATATGTTGATTAATATCGGTAGTGGTGTGGCGTTCAAGTTAATGATTGCCGTGTTTGCCGGTTACGTTGCATTTTCTA
TCGCTGATCGTCCAGGGCTTGCAGTTGGTTTGATTGCGGGGATGCTGGCAAGTGAAGCGGGTGCAGGGATTCTTGGCGGT
ATTATTGCAGGTTTCTTAGCGGGCTATGTGGTGAAAGGGCTAAATGTGATTATTCGATTGCCAGCAAGTCTGACTTCATT
AAAACCGATTTTAATTTTACCGCTCTTAGGTTCGATGATTGTTGGTTTGACGATGATTTACCTCATCAATCCACCAGTGG
CTGAAATTATGAAAGAGCTAAGTAATTGGCTTACTTCAATGGGCGAAGTGAATGCGATTGTGTTAGGCGCAATTATCGGC
GCAATGATGTGTATTGATATGGGCGGGCCGGTAAATAAAGCAGCGTACACTTTTTCGGTTGGATTGATTGCTTCCCAAGT
TTATACACCAATGGCTGCGGCGATGGCCGCGGGTATGGTTCCTCCAATTGGTATGACAGTTGCGACTTGGATTGCTCGCA
ATAAATTTACCGTTAGCCAACGCGATGTGGGGAAAGCATCATTTGTTCTTGGTTTATGTTTTATTTCTGAAGGTGCATTA
CCATTTGTGGCAGCAGATCCAATTCGAGTCATTATTAGCTCTGTGATTGGTGGTGCGGTGGCTGGTGCGATTTCAATGGG
ATTAAATATTACCTTACAAGCTCCGCACGGCGGATTATTTGTCATTCCATTTGTATCTGAGCCATTGAAATATCTTGGTG
CAATTGCGATTGGTGCTTTATCAACAGGTGTGGTTTACGCCATTATTAAATCGAAAAACAATGCGGAATAA

Upstream 100 bases:

>100_bases
TCCGCTTTTGCGGTATCTCAGAGTAACGTCGGTGTGAGTGATTTGAGTTTACTTGACCCCATTTTAGAAAAAGTACAAAT
AACGATGATTGAAGGATAGT

Downstream 100 bases:

>100_bases
TACCGCACTTTGAATGTAAAAAATAATTTTCATTGAAAAAGTTAGACTATGAAATCAAGGACTAAGCTCTGTAATCTACA
GGGCTTAGTCCTTTTAGTTA

Product: preprotein translocase subunit SecG

Products: NA

Alternate protein names: EIIBC-Fru; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MKLFLTQSANVGDAKAYLLHEVFRAAAQKANVSIVETPAEADLVLVFGSVLPNNPELVGKKVFIIGEAIAMISPEVTLAN
ALANGADYVAPKSTVSFTGVSGVKNIVAVTACPTGVAHTFMSAEAIEAYAKKQGWNIKVETRGQVGAGNEITVEEVAAAD
LVFVAADIDVPLDKFKGKPMYRTSTGLALKKTDQEFDKAFKEAKIFDGGNNAGTKEESREKKGVYKHLMTGVSHMLPLVV
AGGLLIAISFMFSFNVIENTGVFQDLPNMLINIGSGVAFKLMIAVFAGYVAFSIADRPGLAVGLIAGMLASEAGAGILGG
IIAGFLAGYVVKGLNVIIRLPASLTSLKPILILPLLGSMIVGLTMIYLINPPVAEIMKELSNWLTSMGEVNAIVLGAIIG
AMMCIDMGGPVNKAAYTFSVGLIASQVYTPMAAAMAAGMVPPIGMTVATWIARNKFTVSQRDVGKASFVLGLCFISEGAL
PFVAADPIRVIISSVIGGAVAGAISMGLNITLQAPHGGLFVIPFVSEPLKYLGAIAIGALSTGVVYAIIKSKNNAE

Sequences:

>Translated_556_residues
MKLFLTQSANVGDAKAYLLHEVFRAAAQKANVSIVETPAEADLVLVFGSVLPNNPELVGKKVFIIGEAIAMISPEVTLAN
ALANGADYVAPKSTVSFTGVSGVKNIVAVTACPTGVAHTFMSAEAIEAYAKKQGWNIKVETRGQVGAGNEITVEEVAAAD
LVFVAADIDVPLDKFKGKPMYRTSTGLALKKTDQEFDKAFKEAKIFDGGNNAGTKEESREKKGVYKHLMTGVSHMLPLVV
AGGLLIAISFMFSFNVIENTGVFQDLPNMLINIGSGVAFKLMIAVFAGYVAFSIADRPGLAVGLIAGMLASEAGAGILGG
IIAGFLAGYVVKGLNVIIRLPASLTSLKPILILPLLGSMIVGLTMIYLINPPVAEIMKELSNWLTSMGEVNAIVLGAIIG
AMMCIDMGGPVNKAAYTFSVGLIASQVYTPMAAAMAAGMVPPIGMTVATWIARNKFTVSQRDVGKASFVLGLCFISEGAL
PFVAADPIRVIISSVIGGAVAGAISMGLNITLQAPHGGLFVIPFVSEPLKYLGAIAIGALSTGVVYAIIKSKNNAE
>Mature_556_residues
MKLFLTQSANVGDAKAYLLHEVFRAAAQKANVSIVETPAEADLVLVFGSVLPNNPELVGKKVFIIGEAIAMISPEVTLAN
ALANGADYVAPKSTVSFTGVSGVKNIVAVTACPTGVAHTFMSAEAIEAYAKKQGWNIKVETRGQVGAGNEITVEEVAAAD
LVFVAADIDVPLDKFKGKPMYRTSTGLALKKTDQEFDKAFKEAKIFDGGNNAGTKEESREKKGVYKHLMTGVSHMLPLVV
AGGLLIAISFMFSFNVIENTGVFQDLPNMLINIGSGVAFKLMIAVFAGYVAFSIADRPGLAVGLIAGMLASEAGAGILGG
IIAGFLAGYVVKGLNVIIRLPASLTSLKPILILPLLGSMIVGLTMIYLINPPVAEIMKELSNWLTSMGEVNAIVLGAIIG
AMMCIDMGGPVNKAAYTFSVGLIASQVYTPMAAAMAAGMVPPIGMTVATWIARNKFTVSQRDVGKASFVLGLCFISEGAL
PFVAADPIRVIISSVIGGAVAGAISMGLNITLQAPHGGLFVIPFVSEPLKYLGAIAIGALSTGVVYAIIKSKNNAE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788492, Length=555, Percent_Identity=56.5765765765766, Blast_Score=597, Evalue=1e-172,
Organism=Escherichia coli, GI1786951, Length=432, Percent_Identity=34.2592592592593, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI87082348, Length=428, Percent_Identity=31.3084112149533, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1790386, Length=319, Percent_Identity=39.8119122257053, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1788729, Length=387, Percent_Identity=28.1653746770026, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1790387, Length=90, Percent_Identity=50, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790390, Length=65, Percent_Identity=40, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1788730, Length=89, Percent_Identity=34.8314606741573, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 57876; Mature: 57876

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFLTQSANVGDAKAYLLHEVFRAAAQKANVSIVETPAEADLVLVFGSVLPNNPELVGK
CEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCHHHCCC
KVFIIGEAIAMISPEVTLANALANGADYVAPKSTVSFTGVSGVKNIVAVTACPTGVAHTF
EEEEEEHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEECCHHHHHHEEEEEECCCHHHHHH
MSAEAIEAYAKKQGWNIKVETRGQVGAGNEITVEEVAAADLVFVAADIDVPLDKFKGKPM
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHCEEEEEECCCCCHHHHCCCCC
YRTSTGLALKKTDQEFDKAFKEAKIFDGGNNAGTKEESREKKGVYKHLMTGVSHMLPLVV
EEECCCCEEECCHHHHHHHHHHCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGGLLIAISFMFSFNVIENTGVFQDLPNMLINIGSGVAFKLMIAVFAGYVAFSIADRPGL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCH
AVGLIAGMLASEAGAGILGGIIAGFLAGYVVKGLNVIIRLPASLTSLKPILILPLLGSMI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCHHHHHHHHHHHH
VGLTMIYLINPPVAEIMKELSNWLTSMGEVNAIVLGAIIGAMMCIDMGGPVNKAAYTFSV
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEH
GLIASQVYTPMAAAMAAGMVPPIGMTVATWIARNKFTVSQRDVGKASFVLGLCFISEGAL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCC
PFVAADPIRVIISSVIGGAVAGAISMGLNITLQAPHGGLFVIPFVSEPLKYLGAIAIGAL
CEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHH
STGVVYAIIKSKNNAE
HHCEEEEEEECCCCCC
>Mature Secondary Structure
MKLFLTQSANVGDAKAYLLHEVFRAAAQKANVSIVETPAEADLVLVFGSVLPNNPELVGK
CEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCHHHCCC
KVFIIGEAIAMISPEVTLANALANGADYVAPKSTVSFTGVSGVKNIVAVTACPTGVAHTF
EEEEEEHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEECCHHHHHHEEEEEECCCHHHHHH
MSAEAIEAYAKKQGWNIKVETRGQVGAGNEITVEEVAAADLVFVAADIDVPLDKFKGKPM
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHCEEEEEECCCCCHHHHCCCCC
YRTSTGLALKKTDQEFDKAFKEAKIFDGGNNAGTKEESREKKGVYKHLMTGVSHMLPLVV
EEECCCCEEECCHHHHHHHHHHCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGGLLIAISFMFSFNVIENTGVFQDLPNMLINIGSGVAFKLMIAVFAGYVAFSIADRPGL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCH
AVGLIAGMLASEAGAGILGGIIAGFLAGYVVKGLNVIIRLPASLTSLKPILILPLLGSMI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCHHHHHHHHHHHH
VGLTMIYLINPPVAEIMKELSNWLTSMGEVNAIVLGAIIGAMMCIDMGGPVNKAAYTFSV
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEH
GLIASQVYTPMAAAMAAGMVPPIGMTVATWIARNKFTVSQRDVGKASFVLGLCFISEGAL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCC
PFVAADPIRVIISSVIGGAVAGAISMGLNITLQAPHGGLFVIPFVSEPLKYLGAIAIGAL
CEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHH
STGVVYAIIKSKNNAE
HHCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]