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The map label for this gene is pssA [H]

Identifier: 148827624

GI number: 148827624

Start: 971037

End: 972404

Strand: Direct

Name: pssA [H]

Synonym: CGSHiGG_05335

Alternate gene names: 148827624

Gene position: 971037-972404 (Clockwise)

Preceding gene: 148827622

Following gene: 148827626

Centisome position: 51.45

GC content: 36.84

Gene sequence:

>1368_bases
ATGTTAATCAATAAAACCAAACGAGCTGAACAAAATTTAAATAATTTGCCATTCCTTGCTTTGCAAGCTGAGCAAATTGA
ATTTTTGGGTAGCTCGGCTGAATTTAAAACTCAAATTATTGAATTAATCAGAAACGCAAAAAAACGTATTTATGTCACCG
CACTTTATTGGCAAAAAGATGAAGCAGGGCAGGAAATTCTCGATGAAATTTATCGCGTGAAGCAAGAAAATCCTCACTTG
GATGTAAAAATTCTCATAGATTGGCATCGCGCACAACGCAATTTATTAGGGGCGGAAAAATCTGCCACTAATGCAGATTG
GTATTGCGAGCAACGCCAAACTTATCAGTTACCTGATGATCCGAATATGTTCTTTGGCGTGCCAATTAATACGCGCGAAG
TTTTTGGTGTATTGCATGTCAAAGGCTTTGTATTTGATGATACGGTGCTTTATAGCGGTGCAAGCATTAATAACGTCTAT
CTTCATCAATTTGAAAAATATCGTTACGACCGCTATCAAAAAATCACTCATGCCGAATTAGCTGATTCGATGGTAAATTT
CATCAATGATTACTTGTTAGATTTCAGTGCAGTTTATCCACTTGATGCTACCAACCGCCCTCGCACCAAAGAGATCCGTG
GCAATATTCGCGCTTATCGTAAAGACCTTGCTCAAAATGGTGAATATTCATTAAAAAGTGCGGTGAAATTACCGAATGTT
TTAAGCGTATCGCCACTGTTTGGCTTGGGTGCATCGGGCAACGAATTAAATCAAGTAATTGAAGATTTATTCTTGCAAGT
ACAAAAAAAATTAGTGATTTGTACGCCATATTTTAATTTTCCACGCACATTGCAACATAAAATAGCAACGTTATTGGAAA
ATGGTAAACGAGTAGAAATTATTGTTGGCGATAAAGTCGCAAACGATTTTTATATTCCACCAGAACAACCATTCAAAATG
GCGGGAGCGTTACCTTATCTTTATGAAAGTAATCTTCGCCGTTTCTGTGAAAAATTTGAGACTCAAATTGAAAATGGTCA
GCTTGTGGTGCGTTTATGGCGTGATGGCGATAATACCTACCACTTAAAAGGCGTATGGGTAGATGACCGTTATATTTTAC
TTACGGGCAATAATCTTAACCCTCGAGCATGGCGTTTGGATGCAGAAAATGGCTTATTAATTTACGATCCACAACAACAG
CTTTTAGCCCAAGTGGAAAAAGAGCAAAACCAAATTCGCCAACATACAAAAGTATTAAAACATTACACTGAATTAGAAGA
ATTGAATCAATACCCAGAACCAGTGCAAAAACTTTTGAAAAAATTTGCACGAATTAAAGCAGATAAATTGGTGAAAATGA
TTCTGTAA

Upstream 100 bases:

>100_bases
AAAATTTGTGAGCATTATAACGAAAAAAAGCCTTTTTTCTATTAATAAGCACGTGAAATATTGTAAACTAACGCACTAGT
CTTTAATCACGAGATGGATT

Downstream 100 bases:

>100_bases
TTATAAGAAAAGTTTTATATTTTTTCTTAAATTCGCTTCCAGTATTAATCTGATAAATTTTGTGGCAATCGTTCTAAAAT
GGCTTTCCAATAGGTTGAAG

Product: phosphatidylserine synthase

Products: NA

Alternate protein names: Phosphatidylserine synthase [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MLINKTKRAEQNLNNLPFLALQAEQIEFLGSSAEFKTQIIELIRNAKKRIYVTALYWQKDEAGQEILDEIYRVKQENPHL
DVKILIDWHRAQRNLLGAEKSATNADWYCEQRQTYQLPDDPNMFFGVPINTREVFGVLHVKGFVFDDTVLYSGASINNVY
LHQFEKYRYDRYQKITHAELADSMVNFINDYLLDFSAVYPLDATNRPRTKEIRGNIRAYRKDLAQNGEYSLKSAVKLPNV
LSVSPLFGLGASGNELNQVIEDLFLQVQKKLVICTPYFNFPRTLQHKIATLLENGKRVEIIVGDKVANDFYIPPEQPFKM
AGALPYLYESNLRRFCEKFETQIENGQLVVRLWRDGDNTYHLKGVWVDDRYILLTGNNLNPRAWRLDAENGLLIYDPQQQ
LLAQVEKEQNQIRQHTKVLKHYTELEELNQYPEPVQKLLKKFARIKADKLVKMIL

Sequences:

>Translated_455_residues
MLINKTKRAEQNLNNLPFLALQAEQIEFLGSSAEFKTQIIELIRNAKKRIYVTALYWQKDEAGQEILDEIYRVKQENPHL
DVKILIDWHRAQRNLLGAEKSATNADWYCEQRQTYQLPDDPNMFFGVPINTREVFGVLHVKGFVFDDTVLYSGASINNVY
LHQFEKYRYDRYQKITHAELADSMVNFINDYLLDFSAVYPLDATNRPRTKEIRGNIRAYRKDLAQNGEYSLKSAVKLPNV
LSVSPLFGLGASGNELNQVIEDLFLQVQKKLVICTPYFNFPRTLQHKIATLLENGKRVEIIVGDKVANDFYIPPEQPFKM
AGALPYLYESNLRRFCEKFETQIENGQLVVRLWRDGDNTYHLKGVWVDDRYILLTGNNLNPRAWRLDAENGLLIYDPQQQ
LLAQVEKEQNQIRQHTKVLKHYTELEELNQYPEPVQKLLKKFARIKADKLVKMIL
>Mature_455_residues
MLINKTKRAEQNLNNLPFLALQAEQIEFLGSSAEFKTQIIELIRNAKKRIYVTALYWQKDEAGQEILDEIYRVKQENPHL
DVKILIDWHRAQRNLLGAEKSATNADWYCEQRQTYQLPDDPNMFFGVPINTREVFGVLHVKGFVFDDTVLYSGASINNVY
LHQFEKYRYDRYQKITHAELADSMVNFINDYLLDFSAVYPLDATNRPRTKEIRGNIRAYRKDLAQNGEYSLKSAVKLPNV
LSVSPLFGLGASGNELNQVIEDLFLQVQKKLVICTPYFNFPRTLQHKIATLLENGKRVEIIVGDKVANDFYIPPEQPFKM
AGALPYLYESNLRRFCEKFETQIENGQLVVRLWRDGDNTYHLKGVWVDDRYILLTGNNLNPRAWRLDAENGLLIYDPQQQ
LLAQVEKEQNQIRQHTKVLKHYTELEELNQYPEPVQKLLKKFARIKADKLVKMIL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87082134, Length=431, Percent_Identity=50.5800464037123, Blast_Score=448, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI25143331, Length=458, Percent_Identity=23.5807860262009, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319842, Length=175, Percent_Identity=30.8571428571429, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28572961, Length=464, Percent_Identity=23.9224137931034, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016270
- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: =2.7.8.8 [H]

Molecular weight: Translated: 53094; Mature: 53094

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINKTKRAEQNLNNLPFLALQAEQIEFLGSSAEFKTQIIELIRNAKKRIYVTALYWQKD
CCCCCCHHHHCCCCCCCEEEEEHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCC
EAGQEILDEIYRVKQENPHLDVKILIDWHRAQRNLLGAEKSATNADWYCEQRQTYQLPDD
HHHHHHHHHHHHHHCCCCCEEEEEEEEEHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCC
PNMFFGVPINTREVFGVLHVKGFVFDDTVLYSGASINNVYLHQFEKYRYDRYQKITHAEL
CCEEEEECCCHHHHHEEHEEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ADSMVNFINDYLLDFSAVYPLDATNRPRTKEIRGNIRAYRKDLAQNGEYSLKSAVKLPNV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC
LSVSPLFGLGASGNELNQVIEDLFLQVQKKLVICTPYFNFPRTLQHKIATLLENGKRVEI
EEECCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEE
IVGDKVANDFYIPPEQPFKMAGALPYLYESNLRRFCEKFETQIENGQLVVRLWRDGDNTY
EECCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEE
HLKGVWVDDRYILLTGNNLNPRAWRLDAENGLLIYDPQQQLLAQVEKEQNQIRQHTKVLK
EEEEEEECCEEEEEECCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
HYTELEELNQYPEPVQKLLKKFARIKADKLVKMIL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLINKTKRAEQNLNNLPFLALQAEQIEFLGSSAEFKTQIIELIRNAKKRIYVTALYWQKD
CCCCCCHHHHCCCCCCCEEEEEHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCC
EAGQEILDEIYRVKQENPHLDVKILIDWHRAQRNLLGAEKSATNADWYCEQRQTYQLPDD
HHHHHHHHHHHHHHCCCCCEEEEEEEEEHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCC
PNMFFGVPINTREVFGVLHVKGFVFDDTVLYSGASINNVYLHQFEKYRYDRYQKITHAEL
CCEEEEECCCHHHHHEEHEEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ADSMVNFINDYLLDFSAVYPLDATNRPRTKEIRGNIRAYRKDLAQNGEYSLKSAVKLPNV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC
LSVSPLFGLGASGNELNQVIEDLFLQVQKKLVICTPYFNFPRTLQHKIATLLENGKRVEI
EEECCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEE
IVGDKVANDFYIPPEQPFKMAGALPYLYESNLRRFCEKFETQIENGQLVVRLWRDGDNTY
EECCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEE
HLKGVWVDDRYILLTGNNLNPRAWRLDAENGLLIYDPQQQLLAQVEKEQNQIRQHTKVLK
EEEEEEECCEEEEEECCCCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
HYTELEELNQYPEPVQKLLKKFARIKADKLVKMIL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]