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The map label for this gene is mogA [H]

Identifier: 148827483

GI number: 148827483

Start: 841979

End: 842572

Strand: Direct

Name: mogA [H]

Synonym: CGSHiGG_04480

Alternate gene names: 148827483

Gene position: 841979-842572 (Clockwise)

Preceding gene: 148827482

Following gene: 148827484

Centisome position: 44.62

GC content: 42.93

Gene sequence:

>594_bases
ATGACCGCACTTTTAAAAATTGGTCTGGTGTCTGTTTCTGATCGCGCATCAGCAGGCGTGTATCAAGATCAAGGTATCCC
AGAATTACAGGCTTGGTTAGAACAAGCGTTAGTAGATCCTTTCCATTTAGAAACAAGATTAATCCCTGATGAACAACCGA
TTATTGAACAAACCTTAAAAGAGCTGGTGGATGAACAAGGTTGCCATTTAGTGCTGACAACTGGTGGAACTGGGCCAGCA
AAACGCGATGTAACGCCTGATGCAACCCTTGCGGTAGCGGATCGAGAAATGCCGGGTTTTGGCGAACAAATGCGTCAAGT
GAGTTTGCATTTTGTGCCTACCGCAATTTTATCCCGCCAAGTGGGTGTGATTCGTAAGGAAAGCTTGATTTTAAATCTTC
CTGGGCAACCTAAAGCGATTAAAGAAACCTTAGAGGGCGTGAAAGATAAAGAAGGAAATGTGCTTGTAAAAGGCATTTTT
AGCGCAGTGCCTTATTGTTTGCAACTGATTAACGGCTTATATATTGATACCAAGCCTGAAATCATCGAAAGTTTCCGTCC
TAAATCTGCAAGACGCGAAAATCTGGAGAAATAG

Upstream 100 bases:

>100_bases
GGAATTTTATTCTTCTAACCCTCCAAAAGTGCGGTAAGTTTTTACCGCATTTTTGATTTATCCAATCACGTCAAAATTAT
TTATAAAAATAAGGAAAAAT

Downstream 100 bases:

>100_bases
CATGAAAAAAATCGAAGCAATGATTAAACCCTTTAAATTAGACGATGTGCGAGAAAGTCTTTCAGATATTGGTATTTCAG
GTATGACAATCACGGAAGTA

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTALLKIGLVSVSDRASAGVYQDQGIPELQAWLEQALVDPFHLETRLIPDEQPIIEQTLKELVDEQGCHLVLTTGGTGPA
KRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQVGVIRKESLILNLPGQPKAIKETLEGVKDKEGNVLVKGIF
SAVPYCLQLINGLYIDTKPEIIESFRPKSARRENLEK

Sequences:

>Translated_197_residues
MTALLKIGLVSVSDRASAGVYQDQGIPELQAWLEQALVDPFHLETRLIPDEQPIIEQTLKELVDEQGCHLVLTTGGTGPA
KRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQVGVIRKESLILNLPGQPKAIKETLEGVKDKEGNVLVKGIF
SAVPYCLQLINGLYIDTKPEIIESFRPKSARRENLEK
>Mature_196_residues
TALLKIGLVSVSDRASAGVYQDQGIPELQAWLEQALVDPFHLETRLIPDEQPIIEQTLKELVDEQGCHLVLTTGGTGPAK
RDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQVGVIRKESLILNLPGQPKAIKETLEGVKDKEGNVLVKGIFS
AVPYCLQLINGLYIDTKPEIIESFRPKSARRENLEK

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=175, Percent_Identity=33.7142857142857, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI10880983, Length=175, Percent_Identity=33.7142857142857, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1786190, Length=189, Percent_Identity=79.8941798941799, Blast_Score=323, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI17564954, Length=149, Percent_Identity=36.241610738255, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17136978, Length=144, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24638841, Length=144, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 21705; Mature: 21574

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALLKIGLVSVSDRASAGVYQDQGIPELQAWLEQALVDPFHLETRLIPDEQPIIEQTLK
CCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHEEECCCCCHHHHHHHH
ELVDEQGCHLVLTTGGTGPAKRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQ
HHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VGVIRKESLILNLPGQPKAIKETLEGVKDKEGNVLVKGIFSAVPYCLQLINGLYIDTKPE
HHHEEECCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
IIESFRPKSARRENLEK
HHHHCCCCHHHHCCCCC
>Mature Secondary Structure 
TALLKIGLVSVSDRASAGVYQDQGIPELQAWLEQALVDPFHLETRLIPDEQPIIEQTLK
CCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHEEECCCCCHHHHHHHH
ELVDEQGCHLVLTTGGTGPAKRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQ
HHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VGVIRKESLILNLPGQPKAIKETLEGVKDKEGNVLVKGIFSAVPYCLQLINGLYIDTKPE
HHHEEECCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
IIESFRPKSARRENLEK
HHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]