| Definition | Haemophilus influenzae PittGG chromosome, complete genome. |
|---|---|
| Accession | NC_009567 |
| Length | 1,887,192 |
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The map label for this gene is relA [H]
Identifier: 148827481
GI number: 148827481
Start: 839294
End: 841525
Strand: Direct
Name: relA [H]
Synonym: CGSHiGG_04470
Alternate gene names: 148827481
Gene position: 839294-841525 (Clockwise)
Preceding gene: 148827480
Following gene: 148827482
Centisome position: 44.47
GC content: 40.41
Gene sequence:
>2232_bases ATGGTTGCTGTTCGTGGTTCTCATTTGTTAAATCCGCAGGATTTTGTGATTGAACAATGGTGCACTGGCTTAAAACTAGC AGAACAAACAGAAAAAAGTTTGATCGATGCGTGGTATTACGCACGTGATTTAATGAATGCCTACCCCGATGAAATGAAGA ATGCGACCTTGATGCTGCAGTCTGGCGTGGAAATGGTAGAAATTTTGCACGAACTTAATATGGATGCGGAAACATTGCTT ACTGCCATGTTGTTTCCTATTGTTGCAAATAAATTAACAGACTGGGAAAGTCTAAAAGAAAAATTTGGTGCGAAAATTAC TAAATTACTTAAAGGCGTGTTGGAGATGGATAATATTCGCCAACTTAATGCCAGTCATTCCGCTAACGCTCTGCAAGTGG ATAATGTTCGCCGTATGTTGTTGGCGATGGTGGACGATTTCCGCTGCGTGATCATTAAACTTGCCGAACGTATTACTTTC TTGCGTGATGCAGAGCATCGTTGTGCAGAGGAAGACAAAGTCCTTGCCGTCAAAGAATGTTCTTATATTTATGCCCCTCT TGCCAATCGTCTTGGGATTGGTCAGCTGAAATGGGAGTTAGAAGATTACTGCTTCCGTTATCTTCATCCTGAACAATATC GCGCTATTGCTAAATTATTACAGGAACGTCGTCTTGATCGTGAACATTACATTGCTGATTTCGTCAGTGAGTTGAGCAGT TATTTACGTGAAAATATCAAGCAAGTGGAAGTCTATGGCCGTCCGAAACATATTTACAGCATTTGGCGCAAAATGCAGAA AAAGAATCTTGAGTTCAGCGGTTTATATGATGTAAGAGCGGTCAGAATTATCGTGCAAAAATTGCAAGATTGTTACACCG CACTTGGGATTGTTCATACTCAATTTAAACACTTACCCAAAGAATTTGACGATTATGTAGCTAACCCGAAACCGAACGGT TATCAATCTATTCATACTGTTGTTTTAGGTAAAGGTGGCAAGCCAATTGAAGTACAAATTCGAACCCAACAAATGCATGA TGATGCAGAGTTAGGTATGGCGGCACACTGGAAATATAAAGAAGGCAATACAGGCAGTATGTCTGCCTATGAAGAAAAAA TTGCGTGGTTGCGTAAATTGTTAGCTTGGCAAGATGATATTACGGATTCTGGCAAAGTGATGGCAGAGTTGCGTAGCCAA GTGTTTGATGACCGTGTATATGTGTTTACGCCAAAGGGCGAAGTGGTGGATTTGCCAACGGGATCTACACCATTAGATTT TGCTTATGCCATTCATAGTGAAATTGGTCATCGCTGCATCGGGGCAAAAGTGGCTGGACGTATTGTGCCATTTACCTATC AGCTACAAATGGGCGATCAAATCGATATTATTACCCAGAAAAATCCGAACCCGAGCCGTGACTGGCTAAACCCAAATTTA GGATTTACCCATACGTCAAAATCTCGCGCAAAAATCCAAGCGTGGTTTAAAAAACAAGATCGCGATAAAAATATTCCAGC GGGTAAAGAATTACTCGATAATGAACTCACGCTTTTGAATTTAAGTATTAAGCAAGTGGAACCTTATGCGTTACCACGCT ATAACTTGAAAAATTTGGACGATCTTTATGCAGGTATTGGCAGTGGCGATATTCGTTTAAATAACTTAATCCATTTCTTG CAAAGTAAATTGATTAAAGTGACTGCTGAAGAAGCGGATCAAGAGATTTTGCGTCATGTTGCTAATAAAAGTGCGGTCAA TTCTCAGCAGAAATCTGAAAAGAACAATGGATATGTAATTGTGGAGGGTGTGGGCAATCTTATGCATCATATTGCGCGTT GCTGTCAGCCGATACCAGGCGATGCGATTGTTGGCTATATTACAATGGGACGTGGTATTTCTATTCACCGAGCGGATTGT GAACAATTCTTAGATTTGCAAGCGGCTCATCCAGAACGCGTGGTGGAATCAATTTGGGGCGAAAATTACGCAAGTGGTTT CCATATTAATATCCGTATTGTGGCAGGCGATCGCAATGGCTTATTACGTGATATTACGACGGTTCTGGCAAATGAAAAAA TTAGCGTGTTAGGGGTCTCAAGCCGTGCTGATACCAAAAAACAGCTTGCTACTATTGATATGGAAATTGAACTCCATAAT GTTGAAAGTTTAAGTAAAATATTGGCTCGATTAGCAAAATTAGATGATGTTATAGAAGCGAAACGTTTATAA
Upstream 100 bases:
>100_bases TAACCTTATTCACTACAAAATAACTCGGTTATTCGGTACAATATCCACCCAAAATAAAAGCGACAGGAAGTTGCTTGCTC TTCATCAACAAGGGGGTATT
Downstream 100 bases:
>100_bases AAATAGGAAAATTTATGTATAAAACGACGGGGCTAACCCATTTAATCAATTCCACTAAATATTCATTACAAGGCTTAAAA AGCGCGTTTAAAAATGAAAC
Product: GTP pyrophosphokinase
Products: NA
Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]
Number of amino acids: Translated: 743; Mature: 743
Protein sequence:
>743_residues MVAVRGSHLLNPQDFVIEQWCTGLKLAEQTEKSLIDAWYYARDLMNAYPDEMKNATLMLQSGVEMVEILHELNMDAETLL TAMLFPIVANKLTDWESLKEKFGAKITKLLKGVLEMDNIRQLNASHSANALQVDNVRRMLLAMVDDFRCVIIKLAERITF LRDAEHRCAEEDKVLAVKECSYIYAPLANRLGIGQLKWELEDYCFRYLHPEQYRAIAKLLQERRLDREHYIADFVSELSS YLRENIKQVEVYGRPKHIYSIWRKMQKKNLEFSGLYDVRAVRIIVQKLQDCYTALGIVHTQFKHLPKEFDDYVANPKPNG YQSIHTVVLGKGGKPIEVQIRTQQMHDDAELGMAAHWKYKEGNTGSMSAYEEKIAWLRKLLAWQDDITDSGKVMAELRSQ VFDDRVYVFTPKGEVVDLPTGSTPLDFAYAIHSEIGHRCIGAKVAGRIVPFTYQLQMGDQIDIITQKNPNPSRDWLNPNL GFTHTSKSRAKIQAWFKKQDRDKNIPAGKELLDNELTLLNLSIKQVEPYALPRYNLKNLDDLYAGIGSGDIRLNNLIHFL QSKLIKVTAEEADQEILRHVANKSAVNSQQKSEKNNGYVIVEGVGNLMHHIARCCQPIPGDAIVGYITMGRGISIHRADC EQFLDLQAAHPERVVESIWGENYASGFHINIRIVAGDRNGLLRDITTVLANEKISVLGVSSRADTKKQLATIDMEIELHN VESLSKILARLAKLDDVIEAKRL
Sequences:
>Translated_743_residues MVAVRGSHLLNPQDFVIEQWCTGLKLAEQTEKSLIDAWYYARDLMNAYPDEMKNATLMLQSGVEMVEILHELNMDAETLL TAMLFPIVANKLTDWESLKEKFGAKITKLLKGVLEMDNIRQLNASHSANALQVDNVRRMLLAMVDDFRCVIIKLAERITF LRDAEHRCAEEDKVLAVKECSYIYAPLANRLGIGQLKWELEDYCFRYLHPEQYRAIAKLLQERRLDREHYIADFVSELSS YLRENIKQVEVYGRPKHIYSIWRKMQKKNLEFSGLYDVRAVRIIVQKLQDCYTALGIVHTQFKHLPKEFDDYVANPKPNG YQSIHTVVLGKGGKPIEVQIRTQQMHDDAELGMAAHWKYKEGNTGSMSAYEEKIAWLRKLLAWQDDITDSGKVMAELRSQ VFDDRVYVFTPKGEVVDLPTGSTPLDFAYAIHSEIGHRCIGAKVAGRIVPFTYQLQMGDQIDIITQKNPNPSRDWLNPNL GFTHTSKSRAKIQAWFKKQDRDKNIPAGKELLDNELTLLNLSIKQVEPYALPRYNLKNLDDLYAGIGSGDIRLNNLIHFL QSKLIKVTAEEADQEILRHVANKSAVNSQQKSEKNNGYVIVEGVGNLMHHIARCCQPIPGDAIVGYITMGRGISIHRADC EQFLDLQAAHPERVVESIWGENYASGFHINIRIVAGDRNGLLRDITTVLANEKISVLGVSSRADTKKQLATIDMEIELHN VESLSKILARLAKLDDVIEAKRL >Mature_743_residues MVAVRGSHLLNPQDFVIEQWCTGLKLAEQTEKSLIDAWYYARDLMNAYPDEMKNATLMLQSGVEMVEILHELNMDAETLL TAMLFPIVANKLTDWESLKEKFGAKITKLLKGVLEMDNIRQLNASHSANALQVDNVRRMLLAMVDDFRCVIIKLAERITF LRDAEHRCAEEDKVLAVKECSYIYAPLANRLGIGQLKWELEDYCFRYLHPEQYRAIAKLLQERRLDREHYIADFVSELSS YLRENIKQVEVYGRPKHIYSIWRKMQKKNLEFSGLYDVRAVRIIVQKLQDCYTALGIVHTQFKHLPKEFDDYVANPKPNG YQSIHTVVLGKGGKPIEVQIRTQQMHDDAELGMAAHWKYKEGNTGSMSAYEEKIAWLRKLLAWQDDITDSGKVMAELRSQ VFDDRVYVFTPKGEVVDLPTGSTPLDFAYAIHSEIGHRCIGAKVAGRIVPFTYQLQMGDQIDIITQKNPNPSRDWLNPNL GFTHTSKSRAKIQAWFKKQDRDKNIPAGKELLDNELTLLNLSIKQVEPYALPRYNLKNLDDLYAGIGSGDIRLNNLIHFL QSKLIKVTAEEADQEILRHVANKSAVNSQQKSEKNNGYVIVEGVGNLMHHIARCCQPIPGDAIVGYITMGRGISIHRADC EQFLDLQAAHPERVVESIWGENYASGFHINIRIVAGDRNGLLRDITTVLANEKISVLGVSSRADTKKQLATIDMEIELHN VESLSKILARLAKLDDVIEAKRL
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ACT domain [H]
Homologues:
Organism=Escherichia coli, GI1789147, Length=748, Percent_Identity=62.7005347593583, Blast_Score=994, Evalue=0.0, Organism=Escherichia coli, GI1790082, Length=721, Percent_Identity=32.3162274618585, Blast_Score=394, Evalue=1e-111,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =2.7.6.5 [H]
Molecular weight: Translated: 84639; Mature: 84639
Theoretical pI: Translated: 7.13; Mature: 7.13
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVAVRGSHLLNPQDFVIEQWCTGLKLAEQTEKSLIDAWYYARDLMNAYPDEMKNATLMLQ CEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEHH SGVEMVEILHELNMDAETLLTAMLFPIVANKLTDWESLKEKFGAKITKLLKGVLEMDNIR CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH QLNASHSANALQVDNVRRMLLAMVDDFRCVIIKLAERITFLRDAEHRCAEEDKVLAVKEC HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHH SYIYAPLANRLGIGQLKWELEDYCFRYLHPEQYRAIAKLLQERRLDREHYIADFVSELSS HHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH YLRENIKQVEVYGRPKHIYSIWRKMQKKNLEFSGLYDVRAVRIIVQKLQDCYTALGIVHT HHHHHHHEEHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH QFKHLPKEFDDYVANPKPNGYQSIHTVVLGKGGKPIEVQIRTQQMHDDAELGMAAHWKYK HHHHCCHHHHHHCCCCCCCCHHHEEEEEEECCCCEEEEEEEHHHCCCHHHCCCEEEEEEC EGNTGSMSAYEEKIAWLRKLLAWQDDITDSGKVMAELRSQVFDDRVYVFTPKGEVVDLPT CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCCCEEECCC GSTPLDFAYAIHSEIGHRCIGAKVAGRIVPFTYQLQMGDQIDIITQKNPNPSRDWLNPNL CCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCC GFTHTSKSRAKIQAWFKKQDRDKNIPAGKELLDNELTLLNLSIKQVEPYALPRYNLKNLD CCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEEEEHHHCCCCCCCCCCCCCHH DLYAGIGSGDIRLNNLIHFLQSKLIKVTAEEADQEILRHVANKSAVNSQQKSEKNNGYVI HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEE VEGVGNLMHHIARCCQPIPGDAIVGYITMGRGISIHRADCEQFLDLQAAHPERVVESIWG EECHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHCCCCCHHHHHHHHCC ENYASGFHINIRIVAGDRNGLLRDITTVLANEKISVLGVSSRADTKKQLATIDMEIELHN CCCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHEEEEEEEEECC VESLSKILARLAKLDDVIEAKRL HHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MVAVRGSHLLNPQDFVIEQWCTGLKLAEQTEKSLIDAWYYARDLMNAYPDEMKNATLMLQ CEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEHH SGVEMVEILHELNMDAETLLTAMLFPIVANKLTDWESLKEKFGAKITKLLKGVLEMDNIR CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH QLNASHSANALQVDNVRRMLLAMVDDFRCVIIKLAERITFLRDAEHRCAEEDKVLAVKEC HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHH SYIYAPLANRLGIGQLKWELEDYCFRYLHPEQYRAIAKLLQERRLDREHYIADFVSELSS HHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH YLRENIKQVEVYGRPKHIYSIWRKMQKKNLEFSGLYDVRAVRIIVQKLQDCYTALGIVHT HHHHHHHEEHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH QFKHLPKEFDDYVANPKPNGYQSIHTVVLGKGGKPIEVQIRTQQMHDDAELGMAAHWKYK HHHHCCHHHHHHCCCCCCCCHHHEEEEEEECCCCEEEEEEEHHHCCCHHHCCCEEEEEEC EGNTGSMSAYEEKIAWLRKLLAWQDDITDSGKVMAELRSQVFDDRVYVFTPKGEVVDLPT CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCCCEEECCC GSTPLDFAYAIHSEIGHRCIGAKVAGRIVPFTYQLQMGDQIDIITQKNPNPSRDWLNPNL CCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCEEEEEECCCCCCCCCCCCCCC GFTHTSKSRAKIQAWFKKQDRDKNIPAGKELLDNELTLLNLSIKQVEPYALPRYNLKNLD CCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEEEEHHHCCCCCCCCCCCCCHH DLYAGIGSGDIRLNNLIHFLQSKLIKVTAEEADQEILRHVANKSAVNSQQKSEKNNGYVI HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEE VEGVGNLMHHIARCCQPIPGDAIVGYITMGRGISIHRADCEQFLDLQAAHPERVVESIWG EECHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHCCCCCHHHHHHHHCC ENYASGFHINIRIVAGDRNGLLRDITTVLANEKISVLGVSSRADTKKQLATIDMEIELHN CCCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHEEEEEEEEECC VESLSKILARLAKLDDVIEAKRL HHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7542800 [H]