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The map label for this gene is copA [C]

Identifier: 148827444

GI number: 148827444

Start: 806002

End: 806208

Strand: Reverse

Name: copA [C]

Synonym: CGSHiGG_04265

Alternate gene names: 148827444

Gene position: 806208-806002 (Counterclockwise)

Preceding gene: 148827445

Following gene: 148827443

Centisome position: 42.72

GC content: 35.75

Gene sequence:

>207_bases
ATGAAAACTATCACATTAAACATAAAAGGCATACATTGCGGCTGTTGCGTAAAAAGTCTTACTCAAGTTTTAACTGAATT
AGATGGTGTACAATCTGCTGATGTGCAATTAGAGGGTAAAGCAAATATTACTTTTGATGAAAATCGAGTCAATATTGCAC
AGCTGATTGAGGTCATTGAAGATGCTGGATTTGACGCCACAGAGTAA

Upstream 100 bases:

>100_bases
GACGCCACAGAGTAAAAAAATTTCAATTCAGATTGGTGGGATGACCTGCCAATCTTGTGCCAATCGCATTCATCAATAAA
ACAACTAACAAGGAGTAAAA

Downstream 100 bases:

>100_bases
AAAAATTTCAATTCAGATTGGTGGGATGACCTGCCAATCTTGTGCCAATCGCATTCATCAATAAAACAACTAACAAGGAG
TAAAAATGAAAACTATCACA

Product: mercuric ion scavenger protein

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 68; Mature: 68

Protein sequence:

>68_residues
MKTITLNIKGIHCGCCVKSLTQVLTELDGVQSADVQLEGKANITFDENRVNIAQLIEVIEDAGFDATE

Sequences:

>Translated_68_residues
MKTITLNIKGIHCGCCVKSLTQVLTELDGVQSADVQLEGKANITFDENRVNIAQLIEVIEDAGFDATE
>Mature_68_residues
MKTITLNIKGIHCGCCVKSLTQVLTELDGVQSADVQLEGKANITFDENRVNIAQLIEVIEDAGFDATE

Specific function: Involved In Copper Efflux. [C]

COG id: COG2608

COG function: function code P; Copper chaperone

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00403 HMA [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 7365; Mature: 7365

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTITLNIKGIHCGCCVKSLTQVLTELDGVQSADVQLEGKANITFDENRVNIAQLIEVIE
CCEEEEEECCEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCHHHHHHHHH
DAGFDATE
HCCCCCCC
>Mature Secondary Structure
MKTITLNIKGIHCGCCVKSLTQVLTELDGVQSADVQLEGKANITFDENRVNIAQLIEVIE
CCEEEEEECCEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCHHHHHHHHH
DAGFDATE
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]