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The map label for this gene is intA [H]

Identifier: 148827415

GI number: 148827415

Start: 765439

End: 766458

Strand: Reverse

Name: intA [H]

Synonym: CGSHiGG_04065

Alternate gene names: 148827415

Gene position: 766458-765439 (Counterclockwise)

Preceding gene: 148827416

Following gene: 148827413

Centisome position: 40.61

GC content: 39.02

Gene sequence:

>1020_bases
ATGAGCCTGGGTGCATTTCCTGATTTATCTCTTGCATACGCTAGGGAAATAGCTACAGAATATCGTGGTCTAATTTTACG
TAACATTGATCCGCTAGAATATCGAAACTCTTCGAATATAGAAGAAAAGAAAACAACCTTTGCTGAAATGGCGATTAGAT
GGCGTGATAAGCGTTTAAAATTGGGAAAACTTAAACCCGAAACGGTCAATGACGCTTTCCGCCGCGTGGAATTGCATTTA
TTCCCAAAAATAGCAGATTTGCCCATTGATCAAGCTAATTATAAGACTCTTGAACCTGTATTGTCTCCGCTTAAAAATTC
AAATACGCTTTATAAGATAAACATTGCAATAAATCAGATTTTTAGAATGGCAGAGGATGAAGATTTAATTGTTAAGAATC
CGTTTAGAAAAATTCATGATGAGTTTACTTATGTGGAAACTAAAAATCATCCTACACTTGCACCAGAAGAATTACCCCGC
TTGTTTGAAGTGATGCAAGGGGCAAATTTAGAAAAACCAACCGCACTTTTAATCGAATGGCAATTATTAAGTATTTTGCG
TAGTTCTGAGGCGGTTAGCATTGAATGGGCAGATATTGATTGGGATGCGAAAGCTCTACATATTCCCGCTGAACGAATGA
AAGGCGGTAAGCGTTCCCATAGTGTTCCGCTTTCTCGACAGGCTTTGAATATATTAGAGCAAATGCGCCGTTATAATGGC
AATCGTAAATATGTATTTTGTTCACGCATTGCACCTTATAATCGCCCGATGAATAGCGGTGCGGCAAATGTTGCTTTAAA
GCGTATGGGATTTAAGGGGTTGTTAGTTGCTCACGGTTTACGCAGTATAGCAAGCACTTATTTACATGAATTAGATCGCT
TTTCTTCTGAAGCCATTGAGTTATGTTTATCTCACGAAAATCGGGGGAAAGTGCGCGCGGCTTACGATAAATCGAAAAAA
TGGCGTTCTAGACAAGAGATTATGCAGACGTGGGGGATTATGTGGAGGAATGCAAAATAA

Upstream 100 bases:

>100_bases
ATACATTAAATCTGATGGAAACGGGCTTTATATAAGAATAAAACCTAATGGAACTAAAATTTGGTACTTTGCCTATAAAT
GGCATAAGAAGCACAGAAAA

Downstream 100 bases:

>100_bases
AGGCGTTACGCACTTAACATTGAACGAAGCTCTTGTTTTTTATCGTCAGGCAGGTTCGTGATGATATATTTAAAATAATT
CTGCTCTTCTAGTTTACTAG

Product: prophage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSLGAFPDLSLAYAREIATEYRGLILRNIDPLEYRNSSNIEEKKTTFAEMAIRWRDKRLKLGKLKPETVNDAFRRVELHL
FPKIADLPIDQANYKTLEPVLSPLKNSNTLYKINIAINQIFRMAEDEDLIVKNPFRKIHDEFTYVETKNHPTLAPEELPR
LFEVMQGANLEKPTALLIEWQLLSILRSSEAVSIEWADIDWDAKALHIPAERMKGGKRSHSVPLSRQALNILEQMRRYNG
NRKYVFCSRIAPYNRPMNSGAANVALKRMGFKGLLVAHGLRSIASTYLHELDRFSSEAIELCLSHENRGKVRAAYDKSKK
WRSRQEIMQTWGIMWRNAK

Sequences:

>Translated_339_residues
MSLGAFPDLSLAYAREIATEYRGLILRNIDPLEYRNSSNIEEKKTTFAEMAIRWRDKRLKLGKLKPETVNDAFRRVELHL
FPKIADLPIDQANYKTLEPVLSPLKNSNTLYKINIAINQIFRMAEDEDLIVKNPFRKIHDEFTYVETKNHPTLAPEELPR
LFEVMQGANLEKPTALLIEWQLLSILRSSEAVSIEWADIDWDAKALHIPAERMKGGKRSHSVPLSRQALNILEQMRRYNG
NRKYVFCSRIAPYNRPMNSGAANVALKRMGFKGLLVAHGLRSIASTYLHELDRFSSEAIELCLSHENRGKVRAAYDKSKK
WRSRQEIMQTWGIMWRNAK
>Mature_338_residues
SLGAFPDLSLAYAREIATEYRGLILRNIDPLEYRNSSNIEEKKTTFAEMAIRWRDKRLKLGKLKPETVNDAFRRVELHLF
PKIADLPIDQANYKTLEPVLSPLKNSNTLYKINIAINQIFRMAEDEDLIVKNPFRKIHDEFTYVETKNHPTLAPEELPRL
FEVMQGANLEKPTALLIEWQLLSILRSSEAVSIEWADIDWDAKALHIPAERMKGGKRSHSVPLSRQALNILEQMRRYNGN
RKYVFCSRIAPYNRPMNSGAANVALKRMGFKGLLVAHGLRSIASTYLHELDRFSSEAIELCLSHENRGKVRAAYDKSKKW
RSRQEIMQTWGIMWRNAK

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=343, Percent_Identity=38.4839650145773, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI145693166, Length=337, Percent_Identity=26.7062314540059, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788690, Length=338, Percent_Identity=25.1479289940828, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 39252; Mature: 39121

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLGAFPDLSLAYAREIATEYRGLILRNIDPLEYRNSSNIEEKKTTFAEMAIRWRDKRLK
CCCCCCCCHHHHHHHHHHHHHHCEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
LGKLKPETVNDAFRRVELHLFPKIADLPIDQANYKTLEPVLSPLKNSNTLYKINIAINQI
CCCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHH
FRMAEDEDLIVKNPFRKIHDEFTYVETKNHPTLAPEELPRLFEVMQGANLEKPTALLIEW
HHHCCCCCEEEECHHHHHHCHHEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHEEHHH
QLLSILRSSEAVSIEWADIDWDAKALHIPAERMKGGKRSHSVPLSRQALNILEQMRRYNG
HHHHHHHCCCCEEEEEECCCCCCCEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
NRKYVFCSRIAPYNRPMNSGAANVALKRMGFKGLLVAHGLRSIASTYLHELDRFSSEAIE
CCEEEEEECCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCLSHENRGKVRAAYDKSKKWRSRQEIMQTWGIMWRNAK
HHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLGAFPDLSLAYAREIATEYRGLILRNIDPLEYRNSSNIEEKKTTFAEMAIRWRDKRLK
CCCCCCCHHHHHHHHHHHHHHCEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
LGKLKPETVNDAFRRVELHLFPKIADLPIDQANYKTLEPVLSPLKNSNTLYKINIAINQI
CCCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHHH
FRMAEDEDLIVKNPFRKIHDEFTYVETKNHPTLAPEELPRLFEVMQGANLEKPTALLIEW
HHHCCCCCEEEECHHHHHHCHHEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHEEHHH
QLLSILRSSEAVSIEWADIDWDAKALHIPAERMKGGKRSHSVPLSRQALNILEQMRRYNG
HHHHHHHCCCCEEEEEECCCCCCCEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
NRKYVFCSRIAPYNRPMNSGAANVALKRMGFKGLLVAHGLRSIASTYLHELDRFSSEAIE
CCEEEEEECCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCLSHENRGKVRAAYDKSKKWRSRQEIMQTWGIMWRNAK
HHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]