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The map label for this gene is nqrA [H]

Identifier: 148827304

GI number: 148827304

Start: 636375

End: 637718

Strand: Direct

Name: nqrA [H]

Synonym: CGSHiGG_03425

Alternate gene names: 148827304

Gene position: 636375-637718 (Clockwise)

Preceding gene: 148827303

Following gene: 148827305

Centisome position: 33.72

GC content: 38.1

Gene sequence:

>1344_bases
ATGATTACAATTAAGAAAGGTTTGGATCTCCCAATTGCGGGAAAACCAGCACAAGTAATCCATAGCGGCAACGCTGTGAA
TCAAGTTGCGATTCTAGGTGAGGAGTATGTGGGGATGCGTCCTTCAATGAAGGTGCGCGAAGGCGATGTTGTGAAAAAAG
GTCAAGTACTTTTTGAAGACAAAAAAAATCCTGGTGTAATTTTTACAGCCCCTGCAAGCGGTACCATCACTGCAATCAAT
CGTGGCGAAAAACGTGTATTACAATCTGTTGTTATTAATGTAGAAGGTGATGAAAAAATCACTTTTGCAAAATATAGCAC
AGAACAATTGAATACACTTTCTTCTGAACAAGTAAAACAAAACTTGATAGAATCTGGCTTATGGACGGCATTACGTACTC
GTCCATTTAGTAAAGTTCCATCCATTGAAAGTGAAGCATCTTCTATTTTTGTAAATGCGATGGATACCAATCCATTAGCA
GCCGATCCCTCTGTCGTATTAAAAGAATATTCGCAAGACTTCACTAACGGTTTAACCGTATTAAGTCGTCTATTCCCTTC
AAAACCATTACACTTATGTAAAGCGGGCGATTCTAATATTCCCACTACTGATCTTGAAAATTTACAGATTCATGATTTTA
CTGGTGTTCATCCAGCTGGTCTTGTAGGGACGCATATTCACTTTATTGATCCTGTCGGTATTCAAAAAACTGTATGGCAT
ATCAATTATCAAGATGTGATCGCTGTAGGTAAATTATTTACAACAGGCGAACTTTATTCAGAACGAGTAATTTCTCTTGC
AGGTCCTCAAGTGAAACAACCTCGTTTAGTACGTACAATAATCGGTGCTAATCTTTCTCAATTAACCCAAAATGAATTAA
GTGCGGGTAAAAATCGTGTAATTTCTGGCTCAGTTCTTTGTGGTCAAATAGCAAAAGATTCACATGATTATTTAGGTCGC
TATGCTTTGCAAGTATCAGTAATCGCTGAAGGTAATGAAAAAGAATTTTTTGGTTGGATTATGCCACAAGCCAATAAATA
TTCTGTGACTCGTACCGTATTAGGCCACTTCAGTAAAAAATTGTTTAATTTTACTACTTCAGAAAATGGTGGCGAACGTG
CAATGGTGCCAATCGGTAGCTATGAGCGCGTAATGCCATTGGACATTTTACCTACATTATTATTACGTGATTTAATCGTG
GGCGATACCGATGGTGCTCAAGAGTTAGGTTGTCTGGAATTAGACGAAGAAGACTTGGCGTTATGTTCTTTCGTTTGTCC
AGGCAAATATGAATACGGTTCAATCTTGCGTCAAGTCTTAGATAAGATTGAGAAGGAAGGTTAA

Upstream 100 bases:

>100_bases
TTTTTTAGCGGTTTGTCACACTCAAACGTGAGATTGCTTCTAGGGTATTTTTACTATATTAGCAATTGTATTTTTAACCT
TGAAAAGTAGTGCAAATAGT

Downstream 100 bases:

>100_bases
AAATGGGTTTGAAAAATCTTTTTGAAAAAATGGAACCTGCGTTTTTACCCGGTGGTAAATACAGCAAGCTTTATCCGATC
TTTGAATCGATTTATACCTT

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MITIKKGLDLPIAGKPAQVIHSGNAVNQVAILGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVIFTAPASGTITAIN
RGEKRVLQSVVINVEGDEKITFAKYSTEQLNTLSSEQVKQNLIESGLWTALRTRPFSKVPSIESEASSIFVNAMDTNPLA
ADPSVVLKEYSQDFTNGLTVLSRLFPSKPLHLCKAGDSNIPTTDLENLQIHDFTGVHPAGLVGTHIHFIDPVGIQKTVWH
INYQDVIAVGKLFTTGELYSERVISLAGPQVKQPRLVRTIIGANLSQLTQNELSAGKNRVISGSVLCGQIAKDSHDYLGR
YALQVSVIAEGNEKEFFGWIMPQANKYSVTRTVLGHFSKKLFNFTTSENGGERAMVPIGSYERVMPLDILPTLLLRDLIV
GDTDGAQELGCLELDEEDLALCSFVCPGKYEYGSILRQVLDKIEKEG

Sequences:

>Translated_447_residues
MITIKKGLDLPIAGKPAQVIHSGNAVNQVAILGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVIFTAPASGTITAIN
RGEKRVLQSVVINVEGDEKITFAKYSTEQLNTLSSEQVKQNLIESGLWTALRTRPFSKVPSIESEASSIFVNAMDTNPLA
ADPSVVLKEYSQDFTNGLTVLSRLFPSKPLHLCKAGDSNIPTTDLENLQIHDFTGVHPAGLVGTHIHFIDPVGIQKTVWH
INYQDVIAVGKLFTTGELYSERVISLAGPQVKQPRLVRTIIGANLSQLTQNELSAGKNRVISGSVLCGQIAKDSHDYLGR
YALQVSVIAEGNEKEFFGWIMPQANKYSVTRTVLGHFSKKLFNFTTSENGGERAMVPIGSYERVMPLDILPTLLLRDLIV
GDTDGAQELGCLELDEEDLALCSFVCPGKYEYGSILRQVLDKIEKEG
>Mature_447_residues
MITIKKGLDLPIAGKPAQVIHSGNAVNQVAILGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVIFTAPASGTITAIN
RGEKRVLQSVVINVEGDEKITFAKYSTEQLNTLSSEQVKQNLIESGLWTALRTRPFSKVPSIESEASSIFVNAMDTNPLA
ADPSVVLKEYSQDFTNGLTVLSRLFPSKPLHLCKAGDSNIPTTDLENLQIHDFTGVHPAGLVGTHIHFIDPVGIQKTVWH
INYQDVIAVGKLFTTGELYSERVISLAGPQVKQPRLVRTIIGANLSQLTQNELSAGKNRVISGSVLCGQIAKDSHDYLGR
YALQVSVIAEGNEKEFFGWIMPQANKYSVTRTVLGHFSKKLFNFTTSENGGERAMVPIGSYERVMPLDILPTLLLRDLIV
GDTDGAQELGCLELDEEDLALCSFVCPGKYEYGSILRQVLDKIEKEG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 48926; Mature: 48926

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKKGLDLPIAGKPAQVIHSGNAVNQVAILGEEYVGMRPSMKVREGDVVKKGQVLFED
CEEECCCCCCCCCCCCHHHEECCCCCCEEEEECHHHCCCCCCCEECCCCCEECCCEEEEC
KKNPGVIFTAPASGTITAINRGEKRVLQSVVINVEGDEKITFAKYSTEQLNTLSSEQVKQ
CCCCCEEEECCCCCEEEEECCCHHHHHHHHEEEECCCCEEEEEECCHHHHHHHHHHHHHH
NLIESGLWTALRTRPFSKVPSIESEASSIFVNAMDTNPLAADPSVVLKEYSQDFTNGLTV
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LSRLFPSKPLHLCKAGDSNIPTTDLENLQIHDFTGVHPAGLVGTHIHFIDPVGIQKTVWH
HHHHCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCHHCCEEEEECCCCCCEEEEE
INYQDVIAVGKLFTTGELYSERVISLAGPQVKQPRLVRTIIGANLSQLTQNELSAGKNRV
ECHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCEE
ISGSVLCGQIAKDSHDYLGRYALQVSVIAEGNEKEFFGWIMPQANKYSVTRTVLGHFSKK
EECCEEECHHHCCCHHHHCEEEEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
LFNFTTSENGGERAMVPIGSYERVMPLDILPTLLLRDLIVGDTDGAQELGCLELDEEDLA
HHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCEEECCCHHH
LCSFVCPGKYEYGSILRQVLDKIEKEG
EEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITIKKGLDLPIAGKPAQVIHSGNAVNQVAILGEEYVGMRPSMKVREGDVVKKGQVLFED
CEEECCCCCCCCCCCCHHHEECCCCCCEEEEECHHHCCCCCCCEECCCCCEECCCEEEEC
KKNPGVIFTAPASGTITAINRGEKRVLQSVVINVEGDEKITFAKYSTEQLNTLSSEQVKQ
CCCCCEEEECCCCCEEEEECCCHHHHHHHHEEEECCCCEEEEEECCHHHHHHHHHHHHHH
NLIESGLWTALRTRPFSKVPSIESEASSIFVNAMDTNPLAADPSVVLKEYSQDFTNGLTV
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LSRLFPSKPLHLCKAGDSNIPTTDLENLQIHDFTGVHPAGLVGTHIHFIDPVGIQKTVWH
HHHHCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCHHCCEEEEECCCCCCEEEEE
INYQDVIAVGKLFTTGELYSERVISLAGPQVKQPRLVRTIIGANLSQLTQNELSAGKNRV
ECHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCEE
ISGSVLCGQIAKDSHDYLGRYALQVSVIAEGNEKEFFGWIMPQANKYSVTRTVLGHFSKK
EECCEEECHHHCCCHHHHCEEEEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
LFNFTTSENGGERAMVPIGSYERVMPLDILPTLLLRDLIVGDTDGAQELGCLELDEEDLA
HHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCEEECCCHHH
LCSFVCPGKYEYGSILRQVLDKIEKEG
EEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA