Click here to switch to the map view.

The map label for this gene is ahpC [C]

Identifier: 148827266

GI number: 148827266

Start: 594864

End: 595466

Strand: Direct

Name: ahpC [C]

Synonym: CGSHiGG_03200

Alternate gene names: 148827266

Gene position: 594864-595466 (Clockwise)

Preceding gene: 148827264

Following gene: 148827267

Centisome position: 31.52

GC content: 39.3

Gene sequence:

>603_bases
ATGGTATTAGTAACCCGTCAAGCACCAGATTTTACTTCATCTGCTGTATTAGGCAATGGCGAAATCGTTGATAACTTCAA
CTTTAAAAAACACATTGCTGGAAAAGCTGCAGTAATCTTTTTCTACCCATTAGACTTTACCTTTGTTTGCCCTTCTGAGT
TAATCGCATTTGACCACCGTTATGAAGAATTCAAAAAACGTGGCGTAGAAGTAGTTGGTGTTTCTATCGACTCTCAATTC
ACTCACAATGCATGGCGTAACACCCCAACTGAAAATGGTGGTATCGGTCAAGTTAAATATGCATTAGCGGCAGACGTAAA
ACACGAAATTGCTCAAGCATACGGTATTGAACATCCAGAAGCAGGCGTTGCATTACGCGCTTCATTCTTAATCGACAAAA
ATGGCGTTGTTCGTCACCAAGTAGTAAACGATCTTCCATTAGGTCGTAATATCGATGAAATGTTACGTATGGTTGATGCA
TTACAATTCCATGAAGATCACGGTGAAGTTTGCCCTGCTCAATGGGAAAAAGGTAAAGAAGGGATGAAAGATAACCCTGA
AGGTGTTGCAAAATACTTAAAACAAAACGCTGATAAACTTTAA

Upstream 100 bases:

>100_bases
ATAGATAAAATCGAGTATAAAATGTCGGCGTTTCAAATAGAATTGCGCCGCTATTTTGTGTGGCAAAACTTTAACTTAAC
TTTATATAGGAATTATGACT

Downstream 100 bases:

>100_bases
TCCGTAATTATTTACAAGAAAGCCACATAATGTGGCTTTTTTTATATTCTTAGATACTTTAGAATAGGCATATCTCTAAC
ACCAAGAGCGGTTCATTTCT

Product: peroxiredoxin

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MVLVTRQAPDFTSSAVLGNGEIVDNFNFKKHIAGKAAVIFFYPLDFTFVCPSELIAFDHRYEEFKKRGVEVVGVSIDSQF
THNAWRNTPTENGGIGQVKYALAADVKHEIAQAYGIEHPEAGVALRASFLIDKNGVVRHQVVNDLPLGRNIDEMLRMVDA
LQFHEDHGEVCPAQWEKGKEGMKDNPEGVAKYLKQNADKL

Sequences:

>Translated_200_residues
MVLVTRQAPDFTSSAVLGNGEIVDNFNFKKHIAGKAAVIFFYPLDFTFVCPSELIAFDHRYEEFKKRGVEVVGVSIDSQF
THNAWRNTPTENGGIGQVKYALAADVKHEIAQAYGIEHPEAGVALRASFLIDKNGVVRHQVVNDLPLGRNIDEMLRMVDA
LQFHEDHGEVCPAQWEKGKEGMKDNPEGVAKYLKQNADKL
>Mature_200_residues
MVLVTRQAPDFTSSAVLGNGEIVDNFNFKKHIAGKAAVIFFYPLDFTFVCPSELIAFDHRYEEFKKRGVEVVGVSIDSQF
THNAWRNTPTENGGIGQVKYALAADVKHEIAQAYGIEHPEAGVALRASFLIDKNGVVRHQVVNDLPLGRNIDEMLRMVDA
LQFHEDHGEVCPAQWEKGKEGMKDNPEGVAKYLKQNADKL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=47.9381443298969, Blast_Score=196, Evalue=9e-51,
Organism=Homo sapiens, GI4505591, Length=189, Percent_Identity=46.5608465608466, Blast_Score=191, Evalue=4e-49,
Organism=Homo sapiens, GI32455266, Length=189, Percent_Identity=46.5608465608466, Blast_Score=191, Evalue=4e-49,
Organism=Homo sapiens, GI32455264, Length=189, Percent_Identity=46.5608465608466, Blast_Score=191, Evalue=4e-49,
Organism=Homo sapiens, GI5802974, Length=196, Percent_Identity=46.9387755102041, Blast_Score=191, Evalue=4e-49,
Organism=Homo sapiens, GI32483377, Length=195, Percent_Identity=46.6666666666667, Blast_Score=189, Evalue=1e-48,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=45.8333333333333, Blast_Score=186, Evalue=8e-48,
Organism=Homo sapiens, GI33188454, Length=83, Percent_Identity=55.421686746988, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI4758638, Length=208, Percent_Identity=28.3653846153846, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786822, Length=192, Percent_Identity=35.4166666666667, Blast_Score=124, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17554494, Length=176, Percent_Identity=47.1590909090909, Blast_Score=179, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI193204376, Length=194, Percent_Identity=44.3298969072165, Blast_Score=176, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI32565831, Length=194, Percent_Identity=44.3298969072165, Blast_Score=176, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI25153706, Length=179, Percent_Identity=29.608938547486, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323613, Length=191, Percent_Identity=41.3612565445026, Blast_Score=165, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6320661, Length=191, Percent_Identity=38.2198952879581, Blast_Score=154, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6319407, Length=181, Percent_Identity=28.1767955801105, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24656348, Length=194, Percent_Identity=48.9690721649485, Blast_Score=201, Evalue=2e-52,
Organism=Drosophila melanogaster, GI17864676, Length=194, Percent_Identity=48.9690721649485, Blast_Score=201, Evalue=2e-52,
Organism=Drosophila melanogaster, GI17738015, Length=198, Percent_Identity=44.4444444444444, Blast_Score=181, Evalue=3e-46,
Organism=Drosophila melanogaster, GI21357347, Length=195, Percent_Identity=43.5897435897436, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI17157991, Length=197, Percent_Identity=43.1472081218274, Blast_Score=177, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24641739, Length=197, Percent_Identity=43.1472081218274, Blast_Score=177, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24581278, Length=182, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17975518, Length=181, Percent_Identity=30.3867403314917, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24652436, Length=181, Percent_Identity=30.3867403314917, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24652434, Length=181, Percent_Identity=30.3867403314917, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22313; Mature: 22313

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLVTRQAPDFTSSAVLGNGEIVDNFNFKKHIAGKAAVIFFYPLDFTFVCPSELIAFDHR
CEEEECCCCCCCCCEEECCCCEEECCCHHHHHCCCEEEEEEEECCEEEECHHHHHHHHHH
YEEFKKRGVEVVGVSIDSQFTHNAWRNTPTENGGIGQVKYALAADVKHEIAQAYGIEHPE
HHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AGVALRASFLIDKNGVVRHQVVNDLPLGRNIDEMLRMVDALQFHEDHGEVCPAQWEKGKE
CCEEEEEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCC
GMKDNPEGVAKYLKQNADKL
CCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVLVTRQAPDFTSSAVLGNGEIVDNFNFKKHIAGKAAVIFFYPLDFTFVCPSELIAFDHR
CEEEECCCCCCCCCEEECCCCEEECCCHHHHHCCCEEEEEEEECCEEEECHHHHHHHHHH
YEEFKKRGVEVVGVSIDSQFTHNAWRNTPTENGGIGQVKYALAADVKHEIAQAYGIEHPE
HHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AGVALRASFLIDKNGVVRHQVVNDLPLGRNIDEMLRMVDALQFHEDHGEVCPAQWEKGKE
CCEEEEEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCC
GMKDNPEGVAKYLKQNADKL
CCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]