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The map label for this gene is citE [H]

Identifier: 148827181

GI number: 148827181

Start: 478437

End: 479312

Strand: Reverse

Name: citE [H]

Synonym: CGSHiGG_02600

Alternate gene names: 148827181

Gene position: 479312-478437 (Counterclockwise)

Preceding gene: 148827182

Following gene: 148827180

Centisome position: 25.4

GC content: 42.01

Gene sequence:

>876_bases
ATGAAATTAAGAAGAAGTATGTTATTTGTGCCAGGCTCAAATGCCGCCATGTTAAGTAATAGCTTTATTTATAAACCAGA
TTCCATTATGTTTGACTTAGAAGATGCGGTTGCTCTCAAAGAAAAAGATTCTGCTCGTTTATTAGTCGCTCACGCACTTC
AACATCCGCTTTATAAAGAAATTGAGACCGTAGTTCGTGTTAATCCGCTAGATTCTGAATTTGGTTTATTGGATTTGAAT
GCGGTAGTGCGTGCGGGTGTGGATGTGGTACGTATGCCAAAAACTGAAAGTGCGCAAGATGTGTTGGATATGGATCACGC
CATTACTGAGATTGAGAAAGCCTGCGGTCGAGAAGCAGGTTCGACTAAAATGCTAGCAGCCATCGAATCACCATTAGGTA
TCACTCAAGCCAACCAAATCGCTTTCGCTTCTAAACGTTTAATTGGTATCGCATTGGGTGCAGAGGATTACGTACGTAAC
TTAAAAACCGAGCGTTCACCAGAGGGGATTGAACTGCTTTTTGCTCGTTGTTCTATTTTACAAGCGGCACGTGCGGCTGG
CATTCAGGCTTTTGATACCGTATATTCTAACGCGAACAATGAAGAAGGCTTCTTAAAAGAGGCTGCGTTAATTAAACAGC
TTGGTTTTGACGGTAAATCCTTAATCAACCCACGCCAAATTGAATTGTTACACAACTTATTTGCACCGACACAAAAAGAC
GTGGAGCAGGCAAAACGCATTATTGAAGCGGCAGCAGAAGCTGAACGACAAGGGGCTGGTGTTGTTTCGTTAAACGGTAA
AATGATTGATGCACCGATTATTGATCGCGCAAAACTTGTATTAGAACGTGCGAAATCAGGTATTCGTGAAGAGTAA

Upstream 100 bases:

>100_bases
TTGTAGAAGACAAAGGGGCGTTAGATTGCGTGTTACAAGCTCGAGTAAAAGCTGCTGCAATGCGTGCAACTGATGAAATG
ATTAACTGGGAGGCTGTGTT

Downstream 100 bases:

>100_bases
AGGGAGATAAAAAGATGACAACAAGAGAACAACGTATTGAAAAATATCACGCTGATCGCTCAGTCTATCAGGCGGTGCCT
AAATGTGAATCCCTTTCTCG

Product: citrate lyase beta chain

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKLRRSMLFVPGSNAAMLSNSFIYKPDSIMFDLEDAVALKEKDSARLLVAHALQHPLYKEIETVVRVNPLDSEFGLLDLN
AVVRAGVDVVRMPKTESAQDVLDMDHAITEIEKACGREAGSTKMLAAIESPLGITQANQIAFASKRLIGIALGAEDYVRN
LKTERSPEGIELLFARCSILQAARAAGIQAFDTVYSNANNEEGFLKEAALIKQLGFDGKSLINPRQIELLHNLFAPTQKD
VEQAKRIIEAAAEAERQGAGVVSLNGKMIDAPIIDRAKLVLERAKSGIREE

Sequences:

>Translated_291_residues
MKLRRSMLFVPGSNAAMLSNSFIYKPDSIMFDLEDAVALKEKDSARLLVAHALQHPLYKEIETVVRVNPLDSEFGLLDLN
AVVRAGVDVVRMPKTESAQDVLDMDHAITEIEKACGREAGSTKMLAAIESPLGITQANQIAFASKRLIGIALGAEDYVRN
LKTERSPEGIELLFARCSILQAARAAGIQAFDTVYSNANNEEGFLKEAALIKQLGFDGKSLINPRQIELLHNLFAPTQKD
VEQAKRIIEAAAEAERQGAGVVSLNGKMIDAPIIDRAKLVLERAKSGIREE
>Mature_291_residues
MKLRRSMLFVPGSNAAMLSNSFIYKPDSIMFDLEDAVALKEKDSARLLVAHALQHPLYKEIETVVRVNPLDSEFGLLDLN
AVVRAGVDVVRMPKTESAQDVLDMDHAITEIEKACGREAGSTKMLAAIESPLGITQANQIAFASKRLIGIALGAEDYVRN
LKTERSPEGIELLFARCSILQAARAAGIQAFDTVYSNANNEEGFLKEAALIKQLGFDGKSLINPRQIELLHNLFAPTQKD
VEQAKRIIEAAAEAERQGAGVVSLNGKMIDAPIIDRAKLVLERAKSGIREE

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=294, Percent_Identity=26.8707482993197, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI87081764, Length=291, Percent_Identity=76.6323024054983, Blast_Score=445, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17557458, Length=290, Percent_Identity=30, Blast_Score=117, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 31811; Mature: 31811

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRRSMLFVPGSNAAMLSNSFIYKPDSIMFDLEDAVALKEKDSARLLVAHALQHPLYKE
CCCCCCEEEECCCCCHHHCCCEEECCCCEEEEHHHHHHHHCCCCHHHHHHHHHHCHHHHH
IETVVRVNPLDSEFGLLDLNAVVRAGVDVVRMPKTESAQDVLDMDHAITEIEKACGREAG
HHHHHCCCCCCCCCCEEEHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
STKMLAAIESPLGITQANQIAFASKRLIGIALGAEDYVRNLKTERSPEGIELLFARCSIL
CCHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHH
QAARAAGIQAFDTVYSNANNEEGFLKEAALIKQLGFDGKSLINPRQIELLHNLFAPTQKD
HHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHCCCHHH
VEQAKRIIEAAAEAERQGAGVVSLNGKMIDAPIIDRAKLVLERAKSGIREE
HHHHHHHHHHHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLRRSMLFVPGSNAAMLSNSFIYKPDSIMFDLEDAVALKEKDSARLLVAHALQHPLYKE
CCCCCCEEEECCCCCHHHCCCEEECCCCEEEEHHHHHHHHCCCCHHHHHHHHHHCHHHHH
IETVVRVNPLDSEFGLLDLNAVVRAGVDVVRMPKTESAQDVLDMDHAITEIEKACGREAG
HHHHHCCCCCCCCCCEEEHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
STKMLAAIESPLGITQANQIAFASKRLIGIALGAEDYVRNLKTERSPEGIELLFARCSIL
CCHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHH
QAARAAGIQAFDTVYSNANNEEGFLKEAALIKQLGFDGKSLINPRQIELLHNLFAPTQKD
HHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHCCCHHH
VEQAKRIIEAAAEAERQGAGVVSLNGKMIDAPIIDRAKLVLERAKSGIREE
HHHHHHHHHHHHHHHHCCCCEEEECCEEECCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]