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The map label for this gene is era [H]

Identifier: 148827173

GI number: 148827173

Start: 466063

End: 466785

Strand: Reverse

Name: era [H]

Synonym: CGSHiGG_02525

Alternate gene names: 148827173

Gene position: 466785-466063 (Counterclockwise)

Preceding gene: 148827174

Following gene: 148827171

Centisome position: 24.73

GC content: 38.73

Gene sequence:

>723_bases
GTGGATACACCGGGGCTTCATATTGAAGAAAAACGGGCGATTAACCGCTTAATGAACCGTGCCGCAAGTAGTGCTATCGG
CGATGTTGATTTAATTATTTTTGTCGTAGATGGTACACACTGGAATGCAGATGATGAGATGGTGCTAAACAAACTACGTA
ATGCAAAAGCACCCGTTGTGCTTGCTATCAACAAAGTAGATAACATCAAGAATAAAGATGATTTGTTGCCGTTTATTACA
GATCTTAGTAGTAAATTTAACTTTGCTCACATTGTGCCAATTTCTGCACAGCGTGGTAATAATGTTCATGAATTAGAGAA
AATTGTACGCCAATCTTTACGTGAAGGTGTACATCATTTCCCAGAAGATTATGTCACAGACCGCTCGCAACGTTTTATGG
CATCGGAAATAATCCGTGAAAAATTAATGCGTTTTACGGGAGAAGAATTACCCTATTCTGTTACGGTTGAAATCGAACAA
TTCAAAGTAAATGAACGTGGCACTTATGAAATAAATGGCTTAATTCTCGTTGAACGTGAAGGTCAGAAAAAAATGGTCAT
TGGTGCGGGCGGTCAAAAAATTAAAACTATTGGTATGGAAGCTAGAGCCGATATGGAACGTTTATTTGATAACAAAGTCC
ATCTTGAACTTTGGGTAAAAGTGAAATCAGGCTGGGCAGATGATGAACGTGCGCTGCGTAGTTTAGGATATATGGATGAA
TAA

Upstream 100 bases:

>100_bases
AAATTTTAGGACAAAAATTTCAATTACATCGCGTAAAGCACAAACTACCCGTCACCGTATTGTTGGGATTAAAACTGAAG
GTGCGTATCAAGAAATCTAC

Downstream 100 bases:

>100_bases
AGTGCGGTAAAATTTATACGCATAATAAAAATCCCCATTATTGTGATGGGGATTTTTTTGTTTCTAATTTTTCACTGAAT
ACACTTTAAATTTTCCTGTT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MDTPGLHIEEKRAINRLMNRAASSAIGDVDLIIFVVDGTHWNADDEMVLNKLRNAKAPVVLAINKVDNIKNKDDLLPFIT
DLSSKFNFAHIVPISAQRGNNVHELEKIVRQSLREGVHHFPEDYVTDRSQRFMASEIIREKLMRFTGEELPYSVTVEIEQ
FKVNERGTYEINGLILVEREGQKKMVIGAGGQKIKTIGMEARADMERLFDNKVHLELWVKVKSGWADDERALRSLGYMDE

Sequences:

>Translated_240_residues
MDTPGLHIEEKRAINRLMNRAASSAIGDVDLIIFVVDGTHWNADDEMVLNKLRNAKAPVVLAINKVDNIKNKDDLLPFIT
DLSSKFNFAHIVPISAQRGNNVHELEKIVRQSLREGVHHFPEDYVTDRSQRFMASEIIREKLMRFTGEELPYSVTVEIEQ
FKVNERGTYEINGLILVEREGQKKMVIGAGGQKIKTIGMEARADMERLFDNKVHLELWVKVKSGWADDERALRSLGYMDE
>Mature_240_residues
MDTPGLHIEEKRAINRLMNRAASSAIGDVDLIIFVVDGTHWNADDEMVLNKLRNAKAPVVLAINKVDNIKNKDDLLPFIT
DLSSKFNFAHIVPISAQRGNNVHELEKIVRQSLREGVHHFPEDYVTDRSQRFMASEIIREKLMRFTGEELPYSVTVEIEQ
FKVNERGTYEINGLILVEREGQKKMVIGAGGQKIKTIGMEARADMERLFDNKVHLELWVKVKSGWADDERALRSLGYMDE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=240, Percent_Identity=74.5833333333333, Blast_Score=373, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 27431; Mature: 27431

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPGLHIEEKRAINRLMNRAASSAIGDVDLIIFVVDGTHWNADDEMVLNKLRNAKAPVV
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCEE
LAINKVDNIKNKDDLLPFITDLSSKFNFAHIVPISAQRGNNVHELEKIVRQSLREGVHHF
EEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
PEDYVTDRSQRFMASEIIREKLMRFTGEELPYSVTVEIEQFKVNERGTYEINGLILVERE
CHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCEEEEEEEEEEEC
GQKKMVIGAGGQKIKTIGMEARADMERLFDNKVHLELWVKVKSGWADDERALRSLGYMDE
CCEEEEEECCCCEEEEECCHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MDTPGLHIEEKRAINRLMNRAASSAIGDVDLIIFVVDGTHWNADDEMVLNKLRNAKAPVV
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCEE
LAINKVDNIKNKDDLLPFITDLSSKFNFAHIVPISAQRGNNVHELEKIVRQSLREGVHHF
EEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
PEDYVTDRSQRFMASEIIREKLMRFTGEELPYSVTVEIEQFKVNERGTYEINGLILVERE
CHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCEEEEEEEEEEEC
GQKKMVIGAGGQKIKTIGMEARADMERLFDNKVHLELWVKVKSGWADDERALRSLGYMDE
CCEEEEEECCCCEEEEECCHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA