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The map label for this gene is gmk [C]

Identifier: 148827163

GI number: 148827163

Start: 455694

End: 456479

Strand: Reverse

Name: gmk [C]

Synonym: CGSHiGG_02475

Alternate gene names: 148827163

Gene position: 456479-455694 (Counterclockwise)

Preceding gene: 148827164

Following gene: 148827160

Centisome position: 24.19

GC content: 37.28

Gene sequence:

>786_bases
ATGTATAAAGCAGTATTTAGTGATTTTGATGGCACCTTATTAACCTCTCAACATACCATTTCCCCTCGAACTGTTGCGGT
AATTAAGCGTTTAACGGCGAATGGCATTCCTTTTGTGCCAATTTCGGCGCGTTCTCCTCTAGGTATTTTGCCTTATTGGA
AACAGCTTGAAACGAATAATGTGCTTGTTGCATTTAGTGGCGCGCTTATTTTGAACCAAAATCTCGAACCAATTTATAGC
GTACAAATTGAGCCAAAAGATATTTTAGAGATTAATACCGTTTTGGCGGAACATCCTTTGCTTGGCGTGAATTATTATAC
AAATAATGATTGCCATGCTCGTGACGTAGAAAATAAATGGGTGATTTATGAACGCAGCGTTACCAAAATTGAGATTCATC
CTTTTGATGAAGTAGCGACAAGTTCGCCACATAAAATTCAAATTATTGGGGAAGCAGAAGAAATCATTGAGATTGAAGTT
CTTTTAAAGAAAAAATTTCCACATTTAAGTATTTGCCGTTCCCACGCTAATTTTTTAGAGGTAATGCACAAGAGTGCAAC
CAAAGGAAGTGCGGTGCGTTTTTTGGAAGATTATTTTGGCGTACAAACTAATGAAGTGATTGCATTTGGCGATAATTTTA
ATGATCTGGATATGCTAGAACATGCGGGGCTTGGTGTTGCAATGGGAAATGCGCCTGATGAAATTAAACAAGCTGCAAAT
GTGGTTACGGTAACCAATAATGAAGATGGACTTGCATTGATTTTAGAAGAAAAATTTCCTGAATAA

Upstream 100 bases:

>100_bases
TGAAGCGGAAGAAATGGAAAGTTTAGAAACCCAAATTATGCAAGGATTAGGCTTTGATGATCCTTATTTAGCAGAGAAAT
AATCTTTATTCGGAGTAATG

Downstream 100 bases:

>100_bases
TTAGAAAAGAAAGGCTCTCAATTGAGAGCCTTTTAGTTATGCTTCTTGTGAATGATACATTGCTTCAATTTGCTTGCGAT
AACGTTCTAAAATCACTTTT

Product: guanylate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MYKAVFSDFDGTLLTSQHTISPRTVAVIKRLTANGIPFVPISARSPLGILPYWKQLETNNVLVAFSGALILNQNLEPIYS
VQIEPKDILEINTVLAEHPLLGVNYYTNNDCHARDVENKWVIYERSVTKIEIHPFDEVATSSPHKIQIIGEAEEIIEIEV
LLKKKFPHLSICRSHANFLEVMHKSATKGSAVRFLEDYFGVQTNEVIAFGDNFNDLDMLEHAGLGVAMGNAPDEIKQAAN
VVTVTNNEDGLALILEEKFPE

Sequences:

>Translated_261_residues
MYKAVFSDFDGTLLTSQHTISPRTVAVIKRLTANGIPFVPISARSPLGILPYWKQLETNNVLVAFSGALILNQNLEPIYS
VQIEPKDILEINTVLAEHPLLGVNYYTNNDCHARDVENKWVIYERSVTKIEIHPFDEVATSSPHKIQIIGEAEEIIEIEV
LLKKKFPHLSICRSHANFLEVMHKSATKGSAVRFLEDYFGVQTNEVIAFGDNFNDLDMLEHAGLGVAMGNAPDEIKQAAN
VVTVTNNEDGLALILEEKFPE
>Mature_261_residues
MYKAVFSDFDGTLLTSQHTISPRTVAVIKRLTANGIPFVPISARSPLGILPYWKQLETNNVLVAFSGALILNQNLEPIYS
VQIEPKDILEINTVLAEHPLLGVNYYTNNDCHARDVENKWVIYERSVTKIEIHPFDEVATSSPHKIQIIGEAEEIIEIEV
LLKKKFPHLSICRSHANFLEVMHKSATKGSAVRFLEDYFGVQTNEVIAFGDNFNDLDMLEHAGLGVAMGNAPDEIKQAAN
VVTVTNNEDGLALILEEKFPE

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI2367265, Length=272, Percent_Identity=30.8823529411765, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI48994981, Length=239, Percent_Identity=25.9414225941423, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1786982, Length=273, Percent_Identity=24.5421245421245, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081741, Length=251, Percent_Identity=23.5059760956175, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 29127; Mature: 29127

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKAVFSDFDGTLLTSQHTISPRTVAVIKRLTANGIPFVPISARSPLGILPYWKQLETNN
CCCCEECCCCCEEEECCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHCCCCC
VLVAFSGALILNQNLEPIYSVQIEPKDILEINTVLAEHPLLGVNYYTNNDCHARDVENKW
EEEEEECEEEECCCCCCEEEEEECCHHHHHHHHHHHCCCEEEEEEEECCCCCEEECCCEE
VIYERSVTKIEIHPFDEVATSSPHKIQIIGEAEEIIEIEVLLKKKFPHLSICRSHANFLE
EEEECCEEEEEECCCHHHHCCCCCEEEEEECHHHHEEEEEEECCCCCHHHHHHHHHHHHH
VMHKSATKGSAVRFLEDYFGVQTNEVIAFGDNFNDLDMLEHAGLGVAMGNAPDEIKQAAN
HHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCEEEECCCHHHHHHHCC
VVTVTNNEDGLALILEEKFPE
EEEEECCCCCEEEEEECCCCC
>Mature Secondary Structure
MYKAVFSDFDGTLLTSQHTISPRTVAVIKRLTANGIPFVPISARSPLGILPYWKQLETNN
CCCCEECCCCCEEEECCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHCCCCC
VLVAFSGALILNQNLEPIYSVQIEPKDILEINTVLAEHPLLGVNYYTNNDCHARDVENKW
EEEEEECEEEECCCCCCEEEEEECCHHHHHHHHHHHCCCEEEEEEEECCCCCEEECCCEE
VIYERSVTKIEIHPFDEVATSSPHKIQIIGEAEEIIEIEVLLKKKFPHLSICRSHANFLE
EEEECCEEEEEECCCHHHHCCCCCEEEEEECHHHHEEEEEEECCCCCHHHHHHHHHHHHH
VMHKSATKGSAVRFLEDYFGVQTNEVIAFGDNFNDLDMLEHAGLGVAMGNAPDEIKQAAN
HHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCEEEECCCHHHHHHHCC
VVTVTNNEDGLALILEEKFPE
EEEEECCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]