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The map label for this gene is erpA

Identifier: 148827141

GI number: 148827141

Start: 421906

End: 422250

Strand: Direct

Name: erpA

Synonym: CGSHiGG_02350

Alternate gene names: 148827141

Gene position: 421906-422250 (Clockwise)

Preceding gene: 148827138

Following gene: 148827142

Centisome position: 22.36

GC content: 39.13

Gene sequence:

>345_bases
ATGATAGATGATATGGCGGTGCCACTGACATTTACTGATGCAGCGGCAAATAAAGTAAAAAGTTTAATCAGCGAAGAAGA
AAATACTAATTTGAAATTACGCGTGTATATCACAGGGGGTGGTTGCAGCGGTTTCCAATATGGTTTTACCTTTGATGAAA
AAGTCAATGACGGCGATTTAACCATTGAAAAATCAGGGGTTCAACTTGTGATTGACCCGATGAGCTTACAGTATTTAATT
GGTGGCACTGTCGATTACACAGAAGGTTTAGAGGGTTCACGTTTTACTGTAAATAATCCAAATGCTACCAGCACTTGTGG
CTGTGGTTCATCCTTTAGTATCTAA

Upstream 100 bases:

>100_bases
TATAGCACGATTTCTAGGAAAAAACTGGATTGCACTTGAATGGAGTAAAGGGTTATTAGATAATGGCGAGATTGAAATTT
TAGGAAAGTAGGAAATAGTT

Downstream 100 bases:

>100_bases
GATGGATTTTCAATTTACACATTATCAAGGCAATGTATCCGTCAAATGTTCAATGGAACACATTGCCCTTGCTAACTGGT
TCAACACAGAAGTGCGGTCA

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MIDDMAVPLTFTDAAANKVKSLISEEENTNLKLRVYITGGGCSGFQYGFTFDEKVNDGDLTIEKSGVQLVIDPMSLQYLI
GGTVDYTEGLEGSRFTVNNPNATSTCGCGSSFSI

Sequences:

>Translated_114_residues
MIDDMAVPLTFTDAAANKVKSLISEEENTNLKLRVYITGGGCSGFQYGFTFDEKVNDGDLTIEKSGVQLVIDPMSLQYLI
GGTVDYTEGLEGSRFTVNNPNATSTCGCGSSFSI
>Mature_114_residues
MIDDMAVPLTFTDAAANKVKSLISEEENTNLKLRVYITGGGCSGFQYGFTFDEKVNDGDLTIEKSGVQLVIDPMSLQYLI
GGTVDYTEGLEGSRFTVNNPNATSTCGCGSSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=97, Percent_Identity=44.3298969072165, Blast_Score=84, Evalue=3e-17,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=34.9056603773585, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786351, Length=114, Percent_Identity=82.4561403508772, Blast_Score=200, Evalue=2e-53,
Organism=Escherichia coli, GI1788877, Length=108, Percent_Identity=37.962962962963, Blast_Score=70, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=42.5925925925926, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI25146411, Length=113, Percent_Identity=30.0884955752212, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193209025, Length=108, Percent_Identity=31.4814814814815, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=32.0754716981132, Blast_Score=69, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=49.3975903614458, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=33.9622641509434, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_HAEI8 (Q4QJM4)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_249433.1
- HSSP:   O67709
- ProteinModelPortal:   Q4QJM4
- SMR:   Q4QJM4
- STRING:   Q4QJM4
- GeneID:   3431277
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI2029
- eggNOG:   COG0316
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- PhylomeDB:   Q4QJM4
- ProtClustDB:   PRK13623
- BioCyc:   HINF281310:NTHI2029-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 12193; Mature: 12193

Theoretical pI: Translated: 3.97; Mature: 3.97

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDMAVPLTFTDAAANKVKSLISEEENTNLKLRVYITGGGCSGFQYGFTFDEKVNDGDL
CCCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCE
TIEKSGVQLVIDPMSLQYLIGGTVDYTEGLEGSRFTVNNPNATSTCGCGSSFSI
EEECCCCEEEECCCEEEEEECCEEECCCCCCCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIDDMAVPLTFTDAAANKVKSLISEEENTNLKLRVYITGGGCSGFQYGFTFDEKVNDGDL
CCCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCE
TIEKSGVQLVIDPMSLQYLIGGTVDYTEGLEGSRFTVNNPNATSTCGCGSSFSI
EEECCCCEEEECCCEEEEEECCEEECCCCCCCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA