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The map label for this gene is aceE [H]

Identifier: 148827057

GI number: 148827057

Start: 321890

End: 324550

Strand: Direct

Name: aceE [H]

Synonym: CGSHiGG_01840

Alternate gene names: 148827057

Gene position: 321890-324550 (Clockwise)

Preceding gene: 148827055

Following gene: 148827058

Centisome position: 17.06

GC content: 40.36

Gene sequence:

>2661_bases
ATGTCTGAGATTTTAAAAAATGACGTTGATCCAATCGAAACACAAGATTGGTTGCAATCATTAGATTCATTAATTCGTGA
AGAGGGCGTTGAACGTGCTCAATATATCGTTGAGCAAGTTATTGGTCAAGCACGCACAAGTGGTGTTTCATTGCCAACAG
GAGTTACCACTGATTACGTGAATACTATTCCTGTGTCTGAACAACCTGCTTATCCAGGTGATCACGCCATCGAACGTCGT
ATTCGTTCAGCAGTACGTTGGAATGCGATCGCGATGGTTTTACGCAGTCAGAAGAAAGATCTTGATTTAGGTGGGCATAT
TTCCACTTTCCAATCTGCAGCAACAATGTATGAAGTTTGCTACAACCACTTTTTTAAAGCTGCAACAGAGAAAAATGGCG
GCGATTTAATTTTCTTCCAAGGCCATGCAGCTCCTGGTATGTATGCGCGTGCTTTCTTAGAAGGTCGTTTAACTGAAGAA
CAAATGGATAACTTCCGTCAAGAAGCCTTTACTGATGGTTTATCTTCATATCCGCACCCTAAATTAATGCCTGAATTTTG
GCAATTCTCTACGGTTTCTATGGGTTTAGGCCCTGTGAATGCCATCTACCAAGCGCGTTTCTTAAAATATCTCGATAACC
GTGGTTTAAAAGATACCAAAGATCAAAAAGTTTATGCGTTCTTAGGCGATGGCGAGATGGATGAAATTGAGTCTAAAGGT
GCATTAACTTTTGCGGCTCGTGAGAAGTTAGATAACTTAATCTTCACTATCAGCTGTAACTTACAACGTTTAGATGGCCC
TGTGAATGGTAATGGTAAAATCGTTCAAGAGTTAGAAGGACTATTTACTGGTGCTGGCTGGGAAGTGATTAAAGTTTTAT
GGGGCAGCGATTGGGATAAATTATTCGCGAAAGATACTTCAGGTAAATTAACTCAGTTAATGATGGAAGTGGTTGATGGA
GACTATTTAACCTTTAAATCTAAAGATGGTGCATATATTCGTGAACACTTCTTCGGTCGTTATCCAGAAACTGCTGCATT
AGTTGCTGATATGACCGATGATGAAATCTGGGCATTACGCCGTGGTGCACACGATAGCGAAAAATTATATGCAGCCTATG
CAAAAGCACAAAATGCAACGAAACCAGTTGTGATTTTAGCGCATCAAGTTAAAGGTTATAAAATTCCTGAAGCGGAAAGT
AAAAATACCGCTCACCAATCTAAAAAAATGTCTTACGAAAGCCTTAAAGGTTTCCGTGACTTCTTTGAATTACCATTAAC
CGATGAACAAGTAGAAAAATTAGAATACATTAAATTTGCTGAAGGCACACCTGAGTATGAATACTTACATGGTCACCGTA
AAGCATTAAACGGTTATGTTCCTGCTCGTCGTACTAAATTTGATGTTGAATATAAAGTTCCTGCATTAGAAGAGTTTAAA
GCATTATTAGAAGAACAACCTCGTGGTATTTCAACCACTATGGCGTTTACTCGTGCATTAAACATCTTATTAAAAGATAA
AAACATCGGTAAAACTATCGTTCCAATGATTGCGGATGAAGCGCGTACTTTCGGTATGGAAGGTTTATTCCGTCAAGTTG
GTATTTATAACCCACATGGTCAAAACTATGTTCCTTCAGACCGTGATTTAGTGGCTTACTATCGTGAAGCAAAAGATGGT
CAAGTACTACAAGAAGGTATCAATGAATTAGGTGCAACCGCATCTTGGTTAGCAGCAGCGAACTCGTACTCTGTCAATAA
CCAACCGATGATTCCATTCTTCATCTATTACTCAATGTTTGGTTTCCAACGTGTGGGCGATATGATGTGGGCTGCAGGCG
ACCAATTAGCTCGTGGCTTTATGGTAGGGGGTACTTCTGGTCGTACAACCTTAAATGGCGAAGGTTTACAACACGAAGAT
GGCCACAGCCATATTCAAGCGGGTATCATTCCTAACTGTATCACTTACGATCCATCATTCGCTTTTGAAGTTGCTGTAAT
TATGCAAGACGGTATCAACCGTATGTACGGCGAAAGACAAGAAGATGTATTCTATTATATGACTACATTAAATGAAGTGA
TGGATCAACCTGCAATGCCTGCTGGTGCGGAAGAAGGTATCCGTAAAGGTTTATATAAATTTGAAACAGTGGAAGGTAAA
AAAGGCAAAGGTCACGTTCAGTTATTAGGTTCTGGTGCGATTATGCGTCACGTTCGTGAAGCGGCACAAATTCTTGCAAA
TGACTACGGTGTGACTTCAGATGTATTTTCTGCGCCTTCATTCAATGAATTAGCACGCGAAGGTCATGATGCAGCACGTT
GGAACTTATTACACCCAACAGAGACACAACGCGTACCATACGTTGCTCAAGTATTAGCTGATTTACCAACCGTTGCTTCA
ACTGACTATGTGAAAGGTTATGCTGATCAAATCCGTGCATTTGTACCAAGTAAGCACTATCATGTATTAGGTACAGACGG
TTTCGGTCGTTCAGATAGCCGTGCAAACTTACGTGAACACTTCGAAGTTGATGCACGTTATGTTGTGGTTGCTGCACTTT
CTCAATTAGCGAAAGAAGGTACAGTATCTAACCAAGTGGTTGCAGATGCGATTGCGAAATTCGGTTTGAATGTAGATCGT
ATCAATCCGCTTTATGCGTAA

Upstream 100 bases:

>100_bases
TTACAAGATTTGTTAAATGTTTGTGAAAAGCAAATATTGCCGTATTCGTGTTTAGCCTTGTCTAAACTAATATTCACTCA
AAACAGATTAAGGAAAACCT

Downstream 100 bases:

>100_bases
TTGATGAAAACTGCGGTCAAAAAACATTGTGTTTTATGACCGCACTTTAAAAGGAACAAAAAATGTCAAAACAAATTCAA
ATTCCTGATATTGGTAGTGA

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 886; Mature: 885

Protein sequence:

>886_residues
MSEILKNDVDPIETQDWLQSLDSLIREEGVERAQYIVEQVIGQARTSGVSLPTGVTTDYVNTIPVSEQPAYPGDHAIERR
IRSAVRWNAIAMVLRSQKKDLDLGGHISTFQSAATMYEVCYNHFFKAATEKNGGDLIFFQGHAAPGMYARAFLEGRLTEE
QMDNFRQEAFTDGLSSYPHPKLMPEFWQFSTVSMGLGPVNAIYQARFLKYLDNRGLKDTKDQKVYAFLGDGEMDEIESKG
ALTFAAREKLDNLIFTISCNLQRLDGPVNGNGKIVQELEGLFTGAGWEVIKVLWGSDWDKLFAKDTSGKLTQLMMEVVDG
DYLTFKSKDGAYIREHFFGRYPETAALVADMTDDEIWALRRGAHDSEKLYAAYAKAQNATKPVVILAHQVKGYKIPEAES
KNTAHQSKKMSYESLKGFRDFFELPLTDEQVEKLEYIKFAEGTPEYEYLHGHRKALNGYVPARRTKFDVEYKVPALEEFK
ALLEEQPRGISTTMAFTRALNILLKDKNIGKTIVPMIADEARTFGMEGLFRQVGIYNPHGQNYVPSDRDLVAYYREAKDG
QVLQEGINELGATASWLAAANSYSVNNQPMIPFFIYYSMFGFQRVGDMMWAAGDQLARGFMVGGTSGRTTLNGEGLQHED
GHSHIQAGIIPNCITYDPSFAFEVAVIMQDGINRMYGERQEDVFYYMTTLNEVMDQPAMPAGAEEGIRKGLYKFETVEGK
KGKGHVQLLGSGAIMRHVREAAQILANDYGVTSDVFSAPSFNELAREGHDAARWNLLHPTETQRVPYVAQVLADLPTVAS
TDYVKGYADQIRAFVPSKHYHVLGTDGFGRSDSRANLREHFEVDARYVVVAALSQLAKEGTVSNQVVADAIAKFGLNVDR
INPLYA

Sequences:

>Translated_886_residues
MSEILKNDVDPIETQDWLQSLDSLIREEGVERAQYIVEQVIGQARTSGVSLPTGVTTDYVNTIPVSEQPAYPGDHAIERR
IRSAVRWNAIAMVLRSQKKDLDLGGHISTFQSAATMYEVCYNHFFKAATEKNGGDLIFFQGHAAPGMYARAFLEGRLTEE
QMDNFRQEAFTDGLSSYPHPKLMPEFWQFSTVSMGLGPVNAIYQARFLKYLDNRGLKDTKDQKVYAFLGDGEMDEIESKG
ALTFAAREKLDNLIFTISCNLQRLDGPVNGNGKIVQELEGLFTGAGWEVIKVLWGSDWDKLFAKDTSGKLTQLMMEVVDG
DYLTFKSKDGAYIREHFFGRYPETAALVADMTDDEIWALRRGAHDSEKLYAAYAKAQNATKPVVILAHQVKGYKIPEAES
KNTAHQSKKMSYESLKGFRDFFELPLTDEQVEKLEYIKFAEGTPEYEYLHGHRKALNGYVPARRTKFDVEYKVPALEEFK
ALLEEQPRGISTTMAFTRALNILLKDKNIGKTIVPMIADEARTFGMEGLFRQVGIYNPHGQNYVPSDRDLVAYYREAKDG
QVLQEGINELGATASWLAAANSYSVNNQPMIPFFIYYSMFGFQRVGDMMWAAGDQLARGFMVGGTSGRTTLNGEGLQHED
GHSHIQAGIIPNCITYDPSFAFEVAVIMQDGINRMYGERQEDVFYYMTTLNEVMDQPAMPAGAEEGIRKGLYKFETVEGK
KGKGHVQLLGSGAIMRHVREAAQILANDYGVTSDVFSAPSFNELAREGHDAARWNLLHPTETQRVPYVAQVLADLPTVAS
TDYVKGYADQIRAFVPSKHYHVLGTDGFGRSDSRANLREHFEVDARYVVVAALSQLAKEGTVSNQVVADAIAKFGLNVDR
INPLYA
>Mature_885_residues
SEILKNDVDPIETQDWLQSLDSLIREEGVERAQYIVEQVIGQARTSGVSLPTGVTTDYVNTIPVSEQPAYPGDHAIERRI
RSAVRWNAIAMVLRSQKKDLDLGGHISTFQSAATMYEVCYNHFFKAATEKNGGDLIFFQGHAAPGMYARAFLEGRLTEEQ
MDNFRQEAFTDGLSSYPHPKLMPEFWQFSTVSMGLGPVNAIYQARFLKYLDNRGLKDTKDQKVYAFLGDGEMDEIESKGA
LTFAAREKLDNLIFTISCNLQRLDGPVNGNGKIVQELEGLFTGAGWEVIKVLWGSDWDKLFAKDTSGKLTQLMMEVVDGD
YLTFKSKDGAYIREHFFGRYPETAALVADMTDDEIWALRRGAHDSEKLYAAYAKAQNATKPVVILAHQVKGYKIPEAESK
NTAHQSKKMSYESLKGFRDFFELPLTDEQVEKLEYIKFAEGTPEYEYLHGHRKALNGYVPARRTKFDVEYKVPALEEFKA
LLEEQPRGISTTMAFTRALNILLKDKNIGKTIVPMIADEARTFGMEGLFRQVGIYNPHGQNYVPSDRDLVAYYREAKDGQ
VLQEGINELGATASWLAAANSYSVNNQPMIPFFIYYSMFGFQRVGDMMWAAGDQLARGFMVGGTSGRTTLNGEGLQHEDG
HSHIQAGIIPNCITYDPSFAFEVAVIMQDGINRMYGERQEDVFYYMTTLNEVMDQPAMPAGAEEGIRKGLYKFETVEGKK
GKGHVQLLGSGAIMRHVREAAQILANDYGVTSDVFSAPSFNELAREGHDAARWNLLHPTETQRVPYVAQVLADLPTVAST
DYVKGYADQIRAFVPSKHYHVLGTDGFGRSDSRANLREHFEVDARYVVVAALSQLAKEGTVSNQVVADAIAKFGLNVDRI
NPLYA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=889, Percent_Identity=68.6164229471316, Blast_Score=1320, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 99153; Mature: 99022

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEILKNDVDPIETQDWLQSLDSLIREEGVERAQYIVEQVIGQARTSGVSLPTGVTTDYV
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NTIPVSEQPAYPGDHAIERRIRSAVRWNAIAMVLRSQKKDLDLGGHISTFQSAATMYEVC
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
YNHFFKAATEKNGGDLIFFQGHAAPGMYARAFLEGRLTEEQMDNFRQEAFTDGLSSYPHP
HHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
KLMPEFWQFSTVSMGLGPVNAIYQARFLKYLDNRGLKDTKDQKVYAFLGDGEMDEIESKG
CCCHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHCCC
ALTFAAREKLDNLIFTISCNLQRLDGPVNGNGKIVQELEGLFTGAGWEVIKVLWGSDWDK
CEEHHHHHHHCCEEEEEEECCEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHH
LFAKDTSGKLTQLMMEVVDGDYLTFKSKDGAYIREHFFGRYPETAALVADMTDDEIWALR
HHHCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCCHHHHEECCCCHHHHHHH
RGAHDSEKLYAAYAKAQNATKPVVILAHQVKGYKIPEAESKNTAHQSKKMSYESLKGFRD
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHH
FFELPLTDEQVEKLEYIKFAEGTPEYEYLHGHRKALNGYVPARRTKFDVEYKVPALEEFK
HHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHH
ALLEEQPRGISTTMAFTRALNILLKDKNIGKTIVPMIADEARTFGMEGLFRQVGIYNPHG
HHHHHCCCCCHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCC
QNYVPSDRDLVAYYREAKDGQVLQEGINELGATASWLAAANSYSVNNQPMIPFFIYYSMF
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
GFQRVGDMMWAAGDQLARGFMVGGTSGRTTLNGEGLQHEDGHSHIQAGIIPNCITYDPSF
HHHHHHHHHHHHHHHHHCCEEEECCCCCCEECCCCCCCCCCCCCEECCCCCCCEECCCCH
AFEVAVIMQDGINRMYGERQEDVFYYMTTLNEVMDQPAMPAGAEEGIRKGLYKFETVEGK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHEEECCCC
KGKGHVQLLGSGAIMRHVREAAQILANDYGVTSDVFSAPSFNELAREGHDAARWNLLHPT
CCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHCCCCHHHEECCCCC
ETQRVPYVAQVLADLPTVASTDYVKGYADQIRAFVPSKHYHVLGTDGFGRSDSRANLREH
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHH
FEVDARYVVVAALSQLAKEGTVSNQVVADAIAKFGLNVDRINPLYA
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHCCCCCCC
>Mature Secondary Structure 
SEILKNDVDPIETQDWLQSLDSLIREEGVERAQYIVEQVIGQARTSGVSLPTGVTTDYV
CHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NTIPVSEQPAYPGDHAIERRIRSAVRWNAIAMVLRSQKKDLDLGGHISTFQSAATMYEVC
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
YNHFFKAATEKNGGDLIFFQGHAAPGMYARAFLEGRLTEEQMDNFRQEAFTDGLSSYPHP
HHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
KLMPEFWQFSTVSMGLGPVNAIYQARFLKYLDNRGLKDTKDQKVYAFLGDGEMDEIESKG
CCCHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHCCC
ALTFAAREKLDNLIFTISCNLQRLDGPVNGNGKIVQELEGLFTGAGWEVIKVLWGSDWDK
CEEHHHHHHHCCEEEEEEECCEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHH
LFAKDTSGKLTQLMMEVVDGDYLTFKSKDGAYIREHFFGRYPETAALVADMTDDEIWALR
HHHCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCCHHHHEECCCCHHHHHHH
RGAHDSEKLYAAYAKAQNATKPVVILAHQVKGYKIPEAESKNTAHQSKKMSYESLKGFRD
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHH
FFELPLTDEQVEKLEYIKFAEGTPEYEYLHGHRKALNGYVPARRTKFDVEYKVPALEEFK
HHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHH
ALLEEQPRGISTTMAFTRALNILLKDKNIGKTIVPMIADEARTFGMEGLFRQVGIYNPHG
HHHHHCCCCCHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCC
QNYVPSDRDLVAYYREAKDGQVLQEGINELGATASWLAAANSYSVNNQPMIPFFIYYSMF
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
GFQRVGDMMWAAGDQLARGFMVGGTSGRTTLNGEGLQHEDGHSHIQAGIIPNCITYDPSF
HHHHHHHHHHHHHHHHHCCEEEECCCCCCEECCCCCCCCCCCCCEECCCCCCCEECCCCH
AFEVAVIMQDGINRMYGERQEDVFYYMTTLNEVMDQPAMPAGAEEGIRKGLYKFETVEGK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHEEECCCC
KGKGHVQLLGSGAIMRHVREAAQILANDYGVTSDVFSAPSFNELAREGHDAARWNLLHPT
CCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHCCCCHHHEECCCCC
ETQRVPYVAQVLADLPTVASTDYVKGYADQIRAFVPSKHYHVLGTDGFGRSDSRANLREH
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHH
FEVDARYVVVAALSQLAKEGTVSNQVVADAIAKFGLNVDRINPLYA
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]