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The map label for this gene is uvrB [H]

Identifier: 148827044

GI number: 148827044

Start: 303961

End: 305799

Strand: Direct

Name: uvrB [H]

Synonym: CGSHiGG_01775

Alternate gene names: 148827044

Gene position: 303961-305799 (Clockwise)

Preceding gene: 148827035

Following gene: 148827047

Centisome position: 16.11

GC content: 39.15

Gene sequence:

>1839_bases
TTGCACCGAATAAAAACCCTTGCTGCTCAGCTTTATGCAGAAATGAAAGCTTTTTTTCCAGAAAATGCGGTGGAATATTT
TGTGTCTTACTATGATTATTATCAGCCAGAAGCCTATGTGCCAAGCAGTGATACATTTATTGAAAAAGATGCGTCTATTA
ATGATCAAATTGAACAAATGCGACTTTCTGCGACGAAATCTTTTCTAGAACGTCGAGATACCATCGTAGTGGCTTCTGTT
TCTGCAATTTATGGTTTGGGCGATCCTGATAGCTATTTACAAATGATGTTGCATTTACAACAAGGTGCCATTATCGATCA
ACGCCAAATTTTAGCGAAGTTAGCGGAATTACAATATACCCGAAATGATCAAGCATTTCAGCGTGGAACTTTCCGTGTTC
GCGGAGAAATTATTGACATTTTCCCTGCGGAATCTGATGATCGTGCGGTGCGTATTGAATTATTTGATGATGAAATCGAG
CGTTTAAGTTTATTTGATCCGCTCACTGGTAGTAGTTTTGGTGCTGTACCACGTTTTACGATCTATCCTAAAACTCACTA
TGTGACGCCAAGAGAACGTATTTTAGATGCGATAGAAAACATCAAAAAAGAACTGGTATCACGCCGTGAATATTTCATTA
AAGAACATAAACTTTTAGAAGAACAGCGTATCAGCCAACGAACCCAATTTGATATTGAAATGATGAATGAATTGGGCTAT
TGCTCGGGAATTGAAAACTACTCTCGCTATTTATCGGGAAGAAATGAGGGCGAACCACCACCAACATTATTTGATTATAT
GCCCTCTGATGCGATTTTAATTATTGATGAATCTCATGTAACTGTGCCTCAAATTGGCGGGATGTATCGTGGCGACCGTT
CACGTAAAGAAACCTTAGTCGAATATGGTTTCCGTTTGCCGTCCGCATTGGATAATCGTCCGTTACGCTTTGAGGAATTT
GAACGCTTAGCTCCGCAAACCATTTATGTTTCCGCAACACCAGGGCCTTATGAATTAGAAAAATCAGGCAGTGAAATCAT
CGATCAAGTGGTTCGCCCCACTGGTTTACTTGATCCGCTTATTGAAATTCGTCCAGTGTCAATTCAAGTGGATGATTTAC
TTTCCGAAGCTCGCCAAAGAGCGGATAAAAATGAGCGAGTTTTAGTCACAACACTCACTAAAAAAATGGCGGAAGATTTA
ACGGATTATTTAGATGAACACGGGATTCGTGTGCGTTATCTACATTCTGATATTGATACCGTGGAACGCGTCGAAATTAT
CCGTGATTTGCGTTTAGGCGAATTTGATGTATTAGTGGGAATTAACTTATTGCGTGAAGGTTTAGATATTCCAGAAGTGT
CTATTGTGGCGATTTTAGATGCTGACAAAGAAGGATTTTTACGCTCCGAACGTTCTTTAATTCAAACCATCGGCCGTGCT
GCACGAAACTTAAATGGTAAAGCGATTTTATATGCGGATAGCATCACAAAATCCATGGAAAAAGCCATCACCGAAACCAA
TCGTCGTCGTGAAAAACAAACAAAATACAATGAAGAACATGGCATTGTGCCACAGGCATTAAATAAGAAAGTCGGTGAAT
TATTAGATATTGGGCAAGGTGCAAACCAAAAAGCGAAAGCCAATAAACAACGTGGAAAAATGGCGGCAGAACCAACCGCA
CTTTATAATGCACCGAAAAATGCCAAAGAATATCAACAACAAATCAAAAAACTGGAACAACAAATGTATAAATTTGCGCA
AGATTTGGAATTTGAAAAAGCCGCGGCAATTCGCGATCAATTACATCAATTACGTGAACAGTTTGTTTTTGATAACTAA

Upstream 100 bases:

>100_bases
GATGGTTTGGCTCACCAAACTTTGCTTGGGGTAACAGGATCGGGGAAGACGTTTACTATCGCCAATGTAATCGCTCAATT
AAATCGCCCCGCGATGTTAC

Downstream 100 bases:

>100_bases
AAGAAACGCCAGCTTAAGCTGGCGTTCTGTCTATTTATTTTCACCTGAAGAATACAAGCGATTTTTATATAAATAACTAC
CTAATAAAGCGTGAGCCAAT

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MHRIKTLAAQLYAEMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASV
SAIYGLGDPDSYLQMMLHLQQGAIIDQRQILAKLAELQYTRNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIE
RLSLFDPLTGSSFGAVPRFTIYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGY
CSGIENYSRYLSGRNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEF
ERLAPQTIYVSATPGPYELEKSGSEIIDQVVRPTGLLDPLIEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDL
TDYLDEHGIRVRYLHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSIVAILDADKEGFLRSERSLIQTIGRA
ARNLNGKAILYADSITKSMEKAITETNRRREKQTKYNEEHGIVPQALNKKVGELLDIGQGANQKAKANKQRGKMAAEPTA
LYNAPKNAKEYQQQIKKLEQQMYKFAQDLEFEKAAAIRDQLHQLREQFVFDN

Sequences:

>Translated_612_residues
MHRIKTLAAQLYAEMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASV
SAIYGLGDPDSYLQMMLHLQQGAIIDQRQILAKLAELQYTRNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIE
RLSLFDPLTGSSFGAVPRFTIYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGY
CSGIENYSRYLSGRNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEF
ERLAPQTIYVSATPGPYELEKSGSEIIDQVVRPTGLLDPLIEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDL
TDYLDEHGIRVRYLHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSIVAILDADKEGFLRSERSLIQTIGRA
ARNLNGKAILYADSITKSMEKAITETNRRREKQTKYNEEHGIVPQALNKKVGELLDIGQGANQKAKANKQRGKMAAEPTA
LYNAPKNAKEYQQQIKKLEQQMYKFAQDLEFEKAAAIRDQLHQLREQFVFDN
>Mature_612_residues
MHRIKTLAAQLYAEMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQMRLSATKSFLERRDTIVVASV
SAIYGLGDPDSYLQMMLHLQQGAIIDQRQILAKLAELQYTRNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIE
RLSLFDPLTGSSFGAVPRFTIYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGY
CSGIENYSRYLSGRNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLVEYGFRLPSALDNRPLRFEEF
ERLAPQTIYVSATPGPYELEKSGSEIIDQVVRPTGLLDPLIEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDL
TDYLDEHGIRVRYLHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSIVAILDADKEGFLRSERSLIQTIGRA
ARNLNGKAILYADSITKSMEKAITETNRRREKQTKYNEEHGIVPQALNKKVGELLDIGQGANQKAKANKQRGKMAAEPTA
LYNAPKNAKEYQQQIKKLEQQMYKFAQDLEFEKAAAIRDQLHQLREQFVFDN

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=607, Percent_Identity=77.5947281713344, Blast_Score=957, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 70456; Mature: 70456

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRIKTLAAQLYAEMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQM
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
RLSATKSFLERRDTIVVASVSAIYGLGDPDSYLQMMLHLQQGAIIDQRQILAKLAELQYT
HHHHHHHHHHHCCCEEEEEHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
RNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGSSFGAVPRFT
CCCHHHHCCCEEEECEEEEEECCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCCCCCCEE
IYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGY
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
CSGIENYSRYLSGRNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLV
HCCHHHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHH
EYGFRLPSALDNRPLRFEEFERLAPQTIYVSATPGPYELEKSGSEIIDQVVRPTGLLDPL
HHHCCCCHHHCCCCCCHHHHHHCCCCEEEEECCCCCCHHHCCHHHHHHHHHCCCCCCCCH
IEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDLTDYLDEHGIRVRYLHSDIDT
HHEEECEEEHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCHHH
VERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSIVAILDADKEGFLRSERSLIQTIGRA
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
ARNLNGKAILYADSITKSMEKAITETNRRREKQTKYNEEHGIVPQALNKKVGELLDIGQG
HHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
ANQKAKANKQRGKMAAEPTALYNAPKNAKEYQQQIKKLEQQMYKFAQDLEFEKAAAIRDQ
CCCHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LHQLREQFVFDN
HHHHHHHHCCCC
>Mature Secondary Structure
MHRIKTLAAQLYAEMKAFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDQIEQM
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
RLSATKSFLERRDTIVVASVSAIYGLGDPDSYLQMMLHLQQGAIIDQRQILAKLAELQYT
HHHHHHHHHHHCCCEEEEEHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
RNDQAFQRGTFRVRGEIIDIFPAESDDRAVRIELFDDEIERLSLFDPLTGSSFGAVPRFT
CCCHHHHCCCEEEECEEEEEECCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCCCCCCEE
IYPKTHYVTPRERILDAIENIKKELVSRREYFIKEHKLLEEQRISQRTQFDIEMMNELGY
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
CSGIENYSRYLSGRNEGEPPPTLFDYMPSDAILIIDESHVTVPQIGGMYRGDRSRKETLV
HCCHHHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHH
EYGFRLPSALDNRPLRFEEFERLAPQTIYVSATPGPYELEKSGSEIIDQVVRPTGLLDPL
HHHCCCCHHHCCCCCCHHHHHHCCCCEEEEECCCCCCHHHCCHHHHHHHHHCCCCCCCCH
IEIRPVSIQVDDLLSEARQRADKNERVLVTTLTKKMAEDLTDYLDEHGIRVRYLHSDIDT
HHEEECEEEHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCHHH
VERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSIVAILDADKEGFLRSERSLIQTIGRA
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
ARNLNGKAILYADSITKSMEKAITETNRRREKQTKYNEEHGIVPQALNKKVGELLDIGQG
HHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
ANQKAKANKQRGKMAAEPTALYNAPKNAKEYQQQIKKLEQQMYKFAQDLEFEKAAAIRDQ
CCCHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LHQLREQFVFDN
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA