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The map label for this gene is neuA [H]

Identifier: 148827025

GI number: 148827025

Start: 271536

End: 272210

Strand: Reverse

Name: neuA [H]

Synonym: CGSHiGG_01585

Alternate gene names: 148827025

Gene position: 272210-271536 (Counterclockwise)

Preceding gene: 148827027

Following gene: 148827024

Centisome position: 14.42

GC content: 38.96

Gene sequence:

>675_bases
ATGACAAGAATTGCAATTATTCCTGCGAGAGCGGGTTCTAAAGGAATTAAAGACAAAAATTTACAGCTTGTGGGTGGTGT
TTCTTTGGTGGGGCGTGCGATTTTGGCAGCGCAAGAATCGGGTATGTTTGATCAAATTGTGGTGACATCAGACGGTGAAA
ATATTTTAAAAGAAGCCACAAAATACGGCGCAAAACCAGTGGCACGCCCTGAAAGTTTAGCTCAAAGTGATACACGCACC
ATTGATGCTATTTTGCATTGCTTAGAAACACTCAATATTTCACAAGGCACCGCTGCACTTTTGCAACCAACCAGCCCATT
GCGTAATGCTTTAGATATTCGTAATGCAATGGAAATTTTCCTTGGCGGCAAATATAAATCAGTGGTTTCCGCTTGCGAAT
GTGAGCATCATCCTTATAAATCCTTCACTTTAGAAGGCACCGAAGTTCAGCCTATTCACGAATTAACGGATTTTGAATCC
CCACGCCAAAAATTACCGAAATCTTATCGTGCAAATGGTGCAATTTATATTAATGACATTGCAAGTCTCTTTGAAGAAAA
ACGCTTTTTTATTGCCCCAATGCGTTTTTATTTAATGCCAACTTATCGTTCCATTGATATTGATTCCACACTTGATTTGC
AATTAGCCGAAAGTTTAATTTCAAAAGAGTTTTAA

Upstream 100 bases:

>100_bases
TGTTAAACAAAAATGTGGTGCCATATTAAAGATTAGTTTTTGCTAAAACAAGGGAAAGATTCTAGAATAGTCAGCACTTT
TATCACAGAGAGTGAAAATA

Downstream 100 bases:

>100_bases
AAAAATTGGCCGCACTTTTGATCTGCACTCCAAAAGTTGGATTAAATAACCAACTAAGGTGCAGATTTTTTATGACCAAA
TACAATTTTTTTCAAGCAAC

Product: acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEATKYGAKPVARPESLAQSDTRT
IDAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIFLGGKYKSVVSACECEHHPYKSFTLEGTEVQPIHELTDFES
PRQKLPKSYRANGAIYINDIASLFEEKRFFIAPMRFYLMPTYRSIDIDSTLDLQLAESLISKEF

Sequences:

>Translated_224_residues
MTRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEATKYGAKPVARPESLAQSDTRT
IDAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIFLGGKYKSVVSACECEHHPYKSFTLEGTEVQPIHELTDFES
PRQKLPKSYRANGAIYINDIASLFEEKRFFIAPMRFYLMPTYRSIDIDSTLDLQLAESLISKEF
>Mature_223_residues
TRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEATKYGAKPVARPESLAQSDTRTI
DAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIFLGGKYKSVVSACECEHHPYKSFTLEGTEVQPIHELTDFESP
RQKLPKSYRANGAIYINDIASLFEEKRFFIAPMRFYLMPTYRSIDIDSTLDLQLAESLISKEF

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=225, Percent_Identity=28.8888888888889, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 24766; Mature: 24635

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEAT
CCEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
KYGAKPVARPESLAQSDTRTIDAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIF
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCHHHHHHHHHHHHHHHH
LGGKYKSVVSACECEHHPYKSFTLEGTEVQPIHELTDFESPRQKLPKSYRANGAIYINDI
HCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCCHHHHCCHHHCCCCCEEHHHH
ASLFEEKRFFIAPMRFYLMPTYRSIDIDSTLDLQLAESLISKEF
HHHHHHCCCEEECHHHEEECCCCEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEAT
CEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
KYGAKPVARPESLAQSDTRTIDAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIF
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCHHHHHHHHHHHHHHHH
LGGKYKSVVSACECEHHPYKSFTLEGTEVQPIHELTDFESPRQKLPKSYRANGAIYINDI
HCCCHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCCCHHHHCCHHHCCCCCEEHHHH
ASLFEEKRFFIAPMRFYLMPTYRSIDIDSTLDLQLAESLISKEF
HHHHHHCCCEEECHHHEEECCCCEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]