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The map label for this gene is rhtC [C]

Identifier: 148826997

GI number: 148826997

Start: 240528

End: 241157

Strand: Reverse

Name: rhtC [C]

Synonym: CGSHiGG_01425

Alternate gene names: 148826997

Gene position: 241157-240528 (Counterclockwise)

Preceding gene: 148826998

Following gene: 148826996

Centisome position: 12.78

GC content: 34.29

Gene sequence:

>630_bases
ATGCTAAATTTAATCATTGTGCATTTATTTGGATTAATGACGCCAGGGCCTGATTTCTTTTATGTAAGTCGAATGGCGGC
AAGTAACTCTCGTCGTAATACAGTTTGTGGCATTTTAGGCATAACGCTTGGTATCGCTTTTTGGGGAATGCTTTCTATGT
TGGGATTAGCGGTGTTATTTGTCACTATCCCAGCATTACATGGCGTTATTATGTTGCTAGGTGGTAGTTACCTAGCATAT
CTCGGTTTTTTAATGGCTCGCAGTAAAAAATACGCTAAATTTGAATCGCACTCTGATACTGAATTTAATCAACAAACCAC
AATCAAAAAAGAAATTTTGAAAGGGCTTTTAGTGAATTTATCCAATGCAAAAGTCGTGGTGTATTTTAGTAGCGTAATGT
CGCTTGTCTTAGTAAATATCACTGAAATGTGGCAAATTATCTTGGCTTTTGCAGTGATTGTAGTAGAAACATTTTGTTAT
TTTTATGTGATTTCATTGATTTTTTCACGTAATATTGCCAAGCGTTTATACAGTCAATACAGCCGTTATATTGATAATAT
GGCAGGTATTGTATTTTTATTTTTTGGTTGTGTGCTTGTTTATAACGGCATCAACGAAATAATTCATTAA

Upstream 100 bases:

>100_bases
ACGAAAAACTCGAAAATGGTTTTGGCATTATGATCGATGACGTTTTAGCGGCAATTTATGCTGTGATTGTTGTATTTGCT
ATTCAATATTGGATGTTGTG

Downstream 100 bases:

>100_bases
TAGAAAAGGAAGTAACATGACATTAAAAATTGCAATCGCTGGTGCTGGCGGAAGAATGGGGCGTCAATTAATTCAAGCGG
TTCATTCTGCGGAAGGCGTA

Product: hypothetical protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MLNLIIVHLFGLMTPGPDFFYVSRMAASNSRRNTVCGILGITLGIAFWGMLSMLGLAVLFVTIPALHGVIMLLGGSYLAY
LGFLMARSKKYAKFESHSDTEFNQQTTIKKEILKGLLVNLSNAKVVVYFSSVMSLVLVNITEMWQIILAFAVIVVETFCY
FYVISLIFSRNIAKRLYSQYSRYIDNMAGIVFLFFGCVLVYNGINEIIH

Sequences:

>Translated_209_residues
MLNLIIVHLFGLMTPGPDFFYVSRMAASNSRRNTVCGILGITLGIAFWGMLSMLGLAVLFVTIPALHGVIMLLGGSYLAY
LGFLMARSKKYAKFESHSDTEFNQQTTIKKEILKGLLVNLSNAKVVVYFSSVMSLVLVNITEMWQIILAFAVIVVETFCY
FYVISLIFSRNIAKRLYSQYSRYIDNMAGIVFLFFGCVLVYNGINEIIH
>Mature_209_residues
MLNLIIVHLFGLMTPGPDFFYVSRMAASNSRRNTVCGILGITLGIAFWGMLSMLGLAVLFVTIPALHGVIMLLGGSYLAY
LGFLMARSKKYAKFESHSDTEFNQQTTIKKEILKGLLVNLSNAKVVVYFSSVMSLVLVNITEMWQIILAFAVIVVETFCY
FYVISLIFSRNIAKRLYSQYSRYIDNMAGIVFLFFGCVLVYNGINEIIH

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family

Homologues:

Organism=Escherichia coli, GI48994978, Length=204, Percent_Identity=39.2156862745098, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1786522, Length=200, Percent_Identity=27, Blast_Score=84, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1307_HAEIN (Q57320)

Other databases:

- EMBL:   L42023
- PIR:   F64115
- RefSeq:   NP_439458.1
- GeneID:   950239
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1307
- NMPDR:   fig|71421.1.peg.1245
- TIGR:   HI_1307
- HOGENOM:   HBG759042
- OMA:   FAVIVVE
- ProtClustDB:   CLSK789543
- BioCyc:   HINF71421:HI_1307-MONOMER
- InterPro:   IPR004778
- InterPro:   IPR001123
- TIGRFAMs:   TIGR00949

Pfam domain/function: PF01810 LysE

EC number: NA

Molecular weight: Translated: 23506; Mature: 23506

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10aa7ecc)-; HASH(0x109d7018)-; HASH(0x108a97c4)-; HASH(0x1160bd20)-; HASH(0x10bfb44c)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLIIVHLFGLMTPGPDFFYVSRMAASNSRRNTVCGILGITLGIAFWGMLSMLGLAVLF
CHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTIPALHGVIMLLGGSYLAYLGFLMARSKKYAKFESHSDTEFNQQTTIKKEILKGLLVNL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
SNAKVVVYFSSVMSLVLVNITEMWQIILAFAVIVVETFCYFYVISLIFSRNIAKRLYSQY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRYIDNMAGIVFLFFGCVLVYNGINEIIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MLNLIIVHLFGLMTPGPDFFYVSRMAASNSRRNTVCGILGITLGIAFWGMLSMLGLAVLF
CHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTIPALHGVIMLLGGSYLAYLGFLMARSKKYAKFESHSDTEFNQQTTIKKEILKGLLVNL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
SNAKVVVYFSSVMSLVLVNITEMWQIILAFAVIVVETFCYFYVISLIFSRNIAKRLYSQY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRYIDNMAGIVFLFFGCVLVYNGINEIIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800