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The map label for this gene is cusC [C]

Identifier: 148826963

GI number: 148826963

Start: 200150

End: 201514

Strand: Direct

Name: cusC [C]

Synonym: CGSHiGG_01185

Alternate gene names: 148826963

Gene position: 200150-201514 (Clockwise)

Preceding gene: 148826957

Following gene: 148826968

Centisome position: 10.61

GC content: 39.05

Gene sequence:

>1365_bases
ATGTTTAAAATGAAAAATATCACGCTTGCTTTGTTGATGTCTGGTGCATTGGTGGGATGTGCCAATATTGGCGATTCTTA
TCAAGCAAGCCTTGAAGATTACAAGCAATATGAAGAAATTACCAAGCAATATAATGTAAAAGAAAATTGGTGGTCGTTAT
ATGATGATGCGCAATTAAATCGTGTTATAGAGCAAGCTTTAACAAACAATAAAGATTTAGCTAAAGCTGCTGTAGCGGTA
AACCGTGCGCTTTATAGTGCGAATTTAGTGGGTGCAAATTTAGTGCCTGCATTTAATGGTTCAACTTCATCAGCAGCACA
ACGCCGAGTTGATATCAGTACAAACTCTGCCACTTCACACAAAGGTTCTTTAAATGTGAGCTATACATTAGATCTGTGGC
AACGTTTGGCCAATACTGTTGATGCGGCGGAATGGTCGCACAAAGCAACTGCAGAAGATATGGAATCGGCTCGTTTATCA
TTAATCAATTCTGTAGTAACAACTTATTATCAAATTGCTTATTTAAATGATGCAATTAGCACAACCAACGAAACGATCAA
ATATTACACGGATATTGGCAATATTATGCAAACGCGTTTAGCGCAAGGCGTGGCTGATGCAGCCAGCGTTGATCAAGCAC
AACAAGCCATATTAACGGCGCGTAATAACAAATTAAATTTTGAAACCCAACGCAAAACAGCAGAACAAACACTGCGTAAT
CTTCTCAACCTAAAACCAAATGAAGCATTAAATATCACGTTCCCTCACATTATGAATGTGAAAACGGTAGGCGTAAACTT
AAACGTGCCTGTGTCTGTAATTGCAAATCGTCCTGATGTAAAAGCAGCACAATTCCGTTTAAGCAGTGCATTCAAAAATG
CCAAAGCAACTCAAAAAAGTTGGTTCCCAGAGGTTAATTTAGGTGCAAGCCTTTCTTCAACAGCAAGCACGGTTGGTACG
GCGTTACATAACCCTGTGGCTGCTGGCACAGTAGGAATTAGCCTACCGTTCTTAAATTGGAACACCGTAAAATGGAACGT
TAAAATTTCTGAAGCTGACTATGAAACAGCACGTTTAAATTACGAACAACGTATTACCACCGCTCTCAATAATGTGGATA
CCAACTACTTTGCCTTTACCCAAGCGCAAAGTACATTAAGTAATTTACAGCAAACCCATAGTTACAATCAGCGTATCACG
CAATATTATCGAAATCGCTATAATGCGGGCGTATCCGAATTACGCGAATGGTTAGTTGCAGCCAATACGGAAAAATCATC
ACAACTTGCGATTTTAAATGCAAAATATCAAGTGCTGCAAAGTGAAAATGCGGTATATAGCTCAATGGCGGGATATTATT
TGTAA

Upstream 100 bases:

>100_bases
CAAACATTCATTATAAATAAAAGTCACAATATTTATTTTATAAATAAAAAAGTGCGGTTAAAATCATCCGCACTTTTTAG
TTCGTAGAAAGGAAAATTCA

Downstream 100 bases:

>100_bases
AAATCAAATTGGATTAATCTATAAAAAATCCCTGTTAAATTTCTTTAACAGGGATTTTGTTATTTAAATTAAACCTATTA
TTTTGTCGCTTCTTTCACTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MFKMKNITLALLMSGALVGCANIGDSYQASLEDYKQYEEITKQYNVKENWWSLYDDAQLNRVIEQALTNNKDLAKAAVAV
NRALYSANLVGANLVPAFNGSTSSAAQRRVDISTNSATSHKGSLNVSYTLDLWQRLANTVDAAEWSHKATAEDMESARLS
LINSVVTTYYQIAYLNDAISTTNETIKYYTDIGNIMQTRLAQGVADAASVDQAQQAILTARNNKLNFETQRKTAEQTLRN
LLNLKPNEALNITFPHIMNVKTVGVNLNVPVSVIANRPDVKAAQFRLSSAFKNAKATQKSWFPEVNLGASLSSTASTVGT
ALHNPVAAGTVGISLPFLNWNTVKWNVKISEADYETARLNYEQRITTALNNVDTNYFAFTQAQSTLSNLQQTHSYNQRIT
QYYRNRYNAGVSELREWLVAANTEKSSQLAILNAKYQVLQSENAVYSSMAGYYL

Sequences:

>Translated_454_residues
MFKMKNITLALLMSGALVGCANIGDSYQASLEDYKQYEEITKQYNVKENWWSLYDDAQLNRVIEQALTNNKDLAKAAVAV
NRALYSANLVGANLVPAFNGSTSSAAQRRVDISTNSATSHKGSLNVSYTLDLWQRLANTVDAAEWSHKATAEDMESARLS
LINSVVTTYYQIAYLNDAISTTNETIKYYTDIGNIMQTRLAQGVADAASVDQAQQAILTARNNKLNFETQRKTAEQTLRN
LLNLKPNEALNITFPHIMNVKTVGVNLNVPVSVIANRPDVKAAQFRLSSAFKNAKATQKSWFPEVNLGASLSSTASTVGT
ALHNPVAAGTVGISLPFLNWNTVKWNVKISEADYETARLNYEQRITTALNNVDTNYFAFTQAQSTLSNLQQTHSYNQRIT
QYYRNRYNAGVSELREWLVAANTEKSSQLAILNAKYQVLQSENAVYSSMAGYYL
>Mature_454_residues
MFKMKNITLALLMSGALVGCANIGDSYQASLEDYKQYEEITKQYNVKENWWSLYDDAQLNRVIEQALTNNKDLAKAAVAV
NRALYSANLVGANLVPAFNGSTSSAAQRRVDISTNSATSHKGSLNVSYTLDLWQRLANTVDAAEWSHKATAEDMESARLS
LINSVVTTYYQIAYLNDAISTTNETIKYYTDIGNIMQTRLAQGVADAASVDQAQQAILTARNNKLNFETQRKTAEQTLRN
LLNLKPNEALNITFPHIMNVKTVGVNLNVPVSVIANRPDVKAAQFRLSSAFKNAKATQKSWFPEVNLGASLSSTASTVGT
ALHNPVAAGTVGISLPFLNWNTVKWNVKISEADYETARLNYEQRITTALNNVDTNYFAFTQAQSTLSNLQQTHSYNQRIT
QYYRNRYNAGVSELREWLVAANTEKSSQLAILNAKYQVLQSENAVYSSMAGYYL

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=465, Percent_Identity=24.3010752688172, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50352; Mature: 50352

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKMKNITLALLMSGALVGCANIGDSYQASLEDYKQYEEITKQYNVKENWWSLYDDAQLN
CCCCCHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHH
RVIEQALTNNKDLAKAAVAVNRALYSANLVGANLVPAFNGSTSSAAQRRVDISTNSATSH
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHEEEECCCCCCCC
KGSLNVSYTLDLWQRLANTVDAAEWSHKATAEDMESARLSLINSVVTTYYQIAYLNDAIS
CCCEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTNETIKYYTDIGNIMQTRLAQGVADAASVDQAQQAILTARNNKLNFETQRKTAEQTLRN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LLNLKPNEALNITFPHIMNVKTVGVNLNVPVSVIANRPDVKAAQFRLSSAFKNAKATQKS
HHCCCCCCEEEEECCCCEEEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
WFPEVNLGASLSSTASTVGTALHNPVAAGTVGISLPFLNWNTVKWNVKISEADYETARLN
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEECCEEEEEEEEEECCCCHHHHCC
YEQRITTALNNVDTNYFAFTQAQSTLSNLQQTHSYNQRITQYYRNRYNAGVSELREWLVA
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ANTEKSSQLAILNAKYQVLQSENAVYSSMAGYYL
CCCCCCCEEEEEEHHHHHHHCCCHHHHHHCCCCC
>Mature Secondary Structure
MFKMKNITLALLMSGALVGCANIGDSYQASLEDYKQYEEITKQYNVKENWWSLYDDAQLN
CCCCCHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHH
RVIEQALTNNKDLAKAAVAVNRALYSANLVGANLVPAFNGSTSSAAQRRVDISTNSATSH
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHEEEECCCCCCCC
KGSLNVSYTLDLWQRLANTVDAAEWSHKATAEDMESARLSLINSVVTTYYQIAYLNDAIS
CCCEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTNETIKYYTDIGNIMQTRLAQGVADAASVDQAQQAILTARNNKLNFETQRKTAEQTLRN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LLNLKPNEALNITFPHIMNVKTVGVNLNVPVSVIANRPDVKAAQFRLSSAFKNAKATQKS
HHCCCCCCEEEEECCCCEEEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
WFPEVNLGASLSSTASTVGTALHNPVAAGTVGISLPFLNWNTVKWNVKISEADYETARLN
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEECCEEEEEEEEEECCCCHHHHCC
YEQRITTALNNVDTNYFAFTQAQSTLSNLQQTHSYNQRITQYYRNRYNAGVSELREWLVA
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ANTEKSSQLAILNAKYQVLQSENAVYSSMAGYYL
CCCCCCCEEEEEEHHHHHHHCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]