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The map label for this gene is bioD [H]

Identifier: 148826948

GI number: 148826948

Start: 190790

End: 191518

Strand: Reverse

Name: bioD [H]

Synonym: CGSHiGG_01110

Alternate gene names: 148826948

Gene position: 191518-190790 (Counterclockwise)

Preceding gene: 148826949

Following gene: 148826946

Centisome position: 10.15

GC content: 35.53

Gene sequence:

>729_bases
ATGAGTAGCTTTTTTGTCGCAGGGACAGATACGAATGTGGGGAAAACAACAGCAGCACGCGCAATGATTCAAGCCTTGCA
AGAGCAGGGAGTACAAGTTGTCGGCTATAAACCTATTGCTTGTTGTGGAGAAGAGAGTATTTATCCTGTCGCGCAATCAG
AAAATACATCTGATTATGATCATTTCGTAAATGCTGATGTATTAACGCTGATGCATTCAACAAAAGAAAATGTGTCTTAT
CAGGATATTAATAGCTATACTTTTAGTCATTGCGCACCCATGCTCACGCAAGATAAAATGCGAATTAAATTAGATAAAAT
TAATTATGATTTAACGCGTTTGAATCAAACTTATCAATCTGTTGTGGTGGAAGGATCTTTTGGTTTAATGACACCAATGG
CAGAAGGAAAAAGTTTTGCAGATTGGATTACTCAACGAAAAATGCCAGTAGTACTTGTAGTTGGAATTAAAGATGGTTGC
GTAAATCACGCTTTATTAACGGTAAAGGTTATCCAACAGTTGGGTGTGCCGTTATTAGGTTGGATAGCAAATCGAATTAA
TCCATTATTAAGCCATTATGCAGAAATTGTTGATTTACTTGTTGAACATATTGATGCGCCGCTTTTAGGTAAAATTCCTT
ATTTACATAAACCCGAAGAACAAGAATTAGGGCATTATTTAACGAATATAGATCGATTAATGTATATGCAAACAGAGTTC
ATAAAATAA

Upstream 100 bases:

>100_bases
TGTCTATTTATAAGATAAAAAAAGTGAAAATTTGCGTTATCTCAAATTATTAAATAAAAAATTCCTTTAAAATCCACCGC
ACTTTTTAAAGGAGAAAAAA

Downstream 100 bases:

>100_bases
TAAAGTGCGGTTGAATTTTTTTTAGTTTTGTATAAGGGCGAAATATCGCCCTTATTTTGTGTTTGAAAAGAAATATATTA
TTGTGATAATTAAGGTCTTA

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase 1; DTBS 1; Dethiobiotin synthase 1 [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSSFFVAGTDTNVGKTTAARAMIQALQEQGVQVVGYKPIACCGEESIYPVAQSENTSDYDHFVNADVLTLMHSTKENVSY
QDINSYTFSHCAPMLTQDKMRIKLDKINYDLTRLNQTYQSVVVEGSFGLMTPMAEGKSFADWITQRKMPVVLVVGIKDGC
VNHALLTVKVIQQLGVPLLGWIANRINPLLSHYAEIVDLLVEHIDAPLLGKIPYLHKPEEQELGHYLTNIDRLMYMQTEF
IK

Sequences:

>Translated_242_residues
MSSFFVAGTDTNVGKTTAARAMIQALQEQGVQVVGYKPIACCGEESIYPVAQSENTSDYDHFVNADVLTLMHSTKENVSY
QDINSYTFSHCAPMLTQDKMRIKLDKINYDLTRLNQTYQSVVVEGSFGLMTPMAEGKSFADWITQRKMPVVLVVGIKDGC
VNHALLTVKVIQQLGVPLLGWIANRINPLLSHYAEIVDLLVEHIDAPLLGKIPYLHKPEEQELGHYLTNIDRLMYMQTEF
IK
>Mature_241_residues
SSFFVAGTDTNVGKTTAARAMIQALQEQGVQVVGYKPIACCGEESIYPVAQSENTSDYDHFVNADVLTLMHSTKENVSYQ
DINSYTFSHCAPMLTQDKMRIKLDKINYDLTRLNQTYQSVVVEGSFGLMTPMAEGKSFADWITQRKMPVVLVVGIKDGCV
NHALLTVKVIQQLGVPLLGWIANRINPLLSHYAEIVDLLVEHIDAPLLGKIPYLHKPEEQELGHYLTNIDRLMYMQTEFI
K

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI87081944, Length=234, Percent_Identity=39.3162393162393, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786995, Length=228, Percent_Identity=39.0350877192982, Blast_Score=168, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 27158; Mature: 27026

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFFVAGTDTNVGKTTAARAMIQALQEQGVQVVGYKPIACCGEESIYPVAQSENTSDYD
CCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCEECCCCCCCCCCCCCCCCCHH
HFVNADVLTLMHSTKENVSYQDINSYTFSHCAPMLTQDKMRIKLDKINYDLTRLNQTYQS
HHHCHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHH
VVVEGSFGLMTPMAEGKSFADWITQRKMPVVLVVGIKDGCVNHALLTVKVIQQLGVPLLG
HEECCCCCCCCCHHCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHH
WIANRINPLLSHYAEIVDLLVEHIDAPLLGKIPYLHKPEEQELGHYLTNIDRLMYMQTEF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IK
CC
>Mature Secondary Structure 
SSFFVAGTDTNVGKTTAARAMIQALQEQGVQVVGYKPIACCGEESIYPVAQSENTSDYD
CCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCEECCCCCCCCCCCCCCCCCHH
HFVNADVLTLMHSTKENVSYQDINSYTFSHCAPMLTQDKMRIKLDKINYDLTRLNQTYQS
HHHCHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHH
VVVEGSFGLMTPMAEGKSFADWITQRKMPVVLVVGIKDGCVNHALLTVKVIQQLGVPLLG
HEECCCCCCCCCHHCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHH
WIANRINPLLSHYAEIVDLLVEHIDAPLLGKIPYLHKPEEQELGHYLTNIDRLMYMQTEF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]