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The map label for this gene is holC [H]

Identifier: 148826880

GI number: 148826880

Start: 141487

End: 141921

Strand: Reverse

Name: holC [H]

Synonym: CGSHiGG_00750

Alternate gene names: 148826880

Gene position: 141921-141487 (Counterclockwise)

Preceding gene: 148826883

Following gene: 148826879

Centisome position: 7.52

GC content: 36.32

Gene sequence:

>435_bases
ATGGCAAAAACTGCACAATTTTATATTCTTACGGAAAATTGTACTTTAACTGTCGAAGAAATAGCCTGTAATCTTGTTGC
TTCAATATGGCGTTCAGGGAAAAAAGTACTAATTAGTTGCGAAAGTGAGAGCCAAGCATTAGAAATTGATGAACTTTTGT
GGCAACGAGATCCTAATGAATTTGTTCCGCATAATTTATCGGGTGAGGCAACACAATATCCCACACCGATTGAGATTTCA
TGGCTTGGAAAACGAAATTTACAACGCCGCGATATGTTAATTAATTTGCAACAAGAAATCCCAGATTTTAGCCATAGTTT
TACCCAAATTATTGATTTTGTGCCGAAAGATGATGCGTTAAAAACACAAGCTCGAGAACGTTATAAACAATTACGTCTGC
AAGGTTGGAATCTTTCTACTGAAAACGTGGGTTAA

Upstream 100 bases:

>100_bases
CATTTGTAATAATATATATTTAATTATTTATTTTTTAGGTTTTTTTCGTTAAAATTCTACCCTTTTTATAGGGCAAGATT
GAGAAAATAACGGGGCTAAA

Downstream 100 bases:

>100_bases
CAAATGAACGATATTACCTTTTATCAACGCTTTGAAGCCGATATTCTCGCAGGGCGTAAAACCATCACCATTCGAGATAA
ATCCGAAAGCCATTTTAAAG

Product: DNA polymerase III subunit chi

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MAKTAQFYILTENCTLTVEEIACNLVASIWRSGKKVLISCESESQALEIDELLWQRDPNEFVPHNLSGEATQYPTPIEIS
WLGKRNLQRRDMLINLQQEIPDFSHSFTQIIDFVPKDDALKTQARERYKQLRLQGWNLSTENVG

Sequences:

>Translated_144_residues
MAKTAQFYILTENCTLTVEEIACNLVASIWRSGKKVLISCESESQALEIDELLWQRDPNEFVPHNLSGEATQYPTPIEIS
WLGKRNLQRRDMLINLQQEIPDFSHSFTQIIDFVPKDDALKTQARERYKQLRLQGWNLSTENVG
>Mature_143_residues
AKTAQFYILTENCTLTVEEIACNLVASIWRSGKKVLISCESESQALEIDELLWQRDPNEFVPHNLSGEATQYPTPIEISW
LGKRNLQRRDMLINLQQEIPDFSHSFTQIIDFVPKDDALKTQARERYKQLRLQGWNLSTENVG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2927

COG function: function code L; DNA polymerase III, chi subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790709, Length=142, Percent_Identity=49.2957746478873, Blast_Score=153, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007459 [H]

Pfam domain/function: PF04364 DNA_pol3_chi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 16655; Mature: 16524

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTAQFYILTENCTLTVEEIACNLVASIWRSGKKVLISCESESQALEIDELLWQRDPNE
CCCCEEEEEEECCCEEEHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCC
FVPHNLSGEATQYPTPIEISWLGKRNLQRRDMLINLQQEIPDFSHSFTQIIDFVPKDDAL
CCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHEEEHHHHCCCHHHHHHHHHHCCCCCCHH
KTQARERYKQLRLQGWNLSTENVG
HHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AKTAQFYILTENCTLTVEEIACNLVASIWRSGKKVLISCESESQALEIDELLWQRDPNE
CCCEEEEEEECCCEEEHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCCC
FVPHNLSGEATQYPTPIEISWLGKRNLQRRDMLINLQQEIPDFSHSFTQIIDFVPKDDAL
CCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHEEEHHHHCCCHHHHHHHHHHCCCCCCHH
KTQARERYKQLRLQGWNLSTENVG
HHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 7959067 [H]