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The map label for this gene is trpG [H]

Identifier: 148826870

GI number: 148826870

Start: 133097

End: 133678

Strand: Direct

Name: trpG [H]

Synonym: CGSHiGG_00700

Alternate gene names: 148826870

Gene position: 133097-133678 (Clockwise)

Preceding gene: 148826869

Following gene: 148826871

Centisome position: 7.05

GC content: 37.97

Gene sequence:

>582_bases
ATGGCTAATATTTTATTTTTAGATAACTTCGATTCCTTCACTTACAATCTTGTGGATCAATTTCGTGTATTAGGTCACAA
CGTCACAATTTATTGCAATGACTGCGACTTAGAAAAACTGGTAGAAACCGCACTCAATACACCTGATACCATTCTTGCAC
TTTCTCCAGGGCCAGGAACGCCATCAGAAGCTGGGATTTTACTGCCATTGATCGAACGCTTAAAAAATAAAGTGCCGATT
ATTGGAATTTGTTTAGGTCATCAAGCATTGATTCAAGCCTTTGGTGGTAAGGTTGTTCACGCTGGCGAAGTGTTGCATGG
TAAAGTTTCTCGTGTATCCCATGATAACGAAGCGATGTTTAAAGATCTTGCAAATCCAATGCCTGTGGCGCGTTATCATT
CTTTAATGGGACAAGATTTACCAAAAGAATTTATCGTCAATGCGGAATATAATGGCATTATCATGGCAATTCGTCATCGT
GATTTACCCATTTGCGCATTCCAATTTCACCCTGAAAGTATTTTAACTGTGCAAGGTTCGCAATTATTACAACAATCAAT
TGAATGGTTGTTAAATAGATAA

Upstream 100 bases:

>100_bases
TGATCCACAAATGGAAGCTGATGAAACACGCCATAAAGCAGTGGCTGTCTTAAAAGCAATTCGTCAAGTTAATACACAAG
CAAAATAAGGAAGAATTATT

Downstream 100 bases:

>100_bases
GACAGAAAAAAGTGCGGTGATTTTTAACCGCACTTTAAAGGAGAAAAAATGATCACCGTATTCGGACTTAAATCCAAACT
CGCACCACGTCGTGAACAAC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MANILFLDNFDSFTYNLVDQFRVLGHNVTIYCNDCDLEKLVETALNTPDTILALSPGPGTPSEAGILLPLIERLKNKVPI
IGICLGHQALIQAFGGKVVHAGEVLHGKVSRVSHDNEAMFKDLANPMPVARYHSLMGQDLPKEFIVNAEYNGIIMAIRHR
DLPICAFQFHPESILTVQGSQLLQQSIEWLLNR

Sequences:

>Translated_193_residues
MANILFLDNFDSFTYNLVDQFRVLGHNVTIYCNDCDLEKLVETALNTPDTILALSPGPGTPSEAGILLPLIERLKNKVPI
IGICLGHQALIQAFGGKVVHAGEVLHGKVSRVSHDNEAMFKDLANPMPVARYHSLMGQDLPKEFIVNAEYNGIIMAIRHR
DLPICAFQFHPESILTVQGSQLLQQSIEWLLNR
>Mature_192_residues
ANILFLDNFDSFTYNLVDQFRVLGHNVTIYCNDCDLEKLVETALNTPDTILALSPGPGTPSEAGILLPLIERLKNKVPII
GICLGHQALIQAFGGKVVHAGEVLHGKVSRVSHDNEAMFKDLANPMPVARYHSLMGQDLPKEFIVNAEYNGIIMAIRHRD
LPICAFQFHPESILTVQGSQLLQQSIEWLLNR

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=189, Percent_Identity=57.1428571428571, Blast_Score=242, Evalue=1e-65,
Organism=Escherichia coli, GI1789760, Length=183, Percent_Identity=49.7267759562842, Blast_Score=164, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322638, Length=186, Percent_Identity=42.4731182795699, Blast_Score=151, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6324361, Length=208, Percent_Identity=29.3269230769231, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21456; Mature: 21325

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANILFLDNFDSFTYNLVDQFRVLGHNVTIYCNDCDLEKLVETALNTPDTILALSPGPGT
CCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCC
PSEAGILLPLIERLKNKVPIIGICLGHQALIQAFGGKVVHAGEVLHGKVSRVSHDNEAMF
CCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCEEEECHHHHHHHHHCCCCCHHHH
KDLANPMPVARYHSLMGQDLPKEFIVNAEYNGIIMAIRHRDLPICAFQFHPESILTVQGS
HHCCCCCCHHHHHHHHCCCCCHHHEECCCCCCEEEEEECCCCCEEEEEECCCEEEEECHH
QLLQQSIEWLLNR
HHHHHHHHHHHCC
>Mature Secondary Structure 
ANILFLDNFDSFTYNLVDQFRVLGHNVTIYCNDCDLEKLVETALNTPDTILALSPGPGT
CEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCC
PSEAGILLPLIERLKNKVPIIGICLGHQALIQAFGGKVVHAGEVLHGKVSRVSHDNEAMF
CCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCEEEECHHHHHHHHHCCCCCHHHH
KDLANPMPVARYHSLMGQDLPKEFIVNAEYNGIIMAIRHRDLPICAFQFHPESILTVQGS
HHCCCCCCHHHHHHHHCCCCCHHHEECCCCCCEEEEEECCCCCEEEEEECCCEEEEECHH
QLLQQSIEWLLNR
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]