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The map label for this gene is phoR [H]

Identifier: 148826861

GI number: 148826861

Start: 123991

End: 125268

Strand: Reverse

Name: phoR [H]

Synonym: CGSHiGG_00655

Alternate gene names: 148826861

Gene position: 125268-123991 (Counterclockwise)

Preceding gene: 148826862

Following gene: 148826851

Centisome position: 6.64

GC content: 27.78

Gene sequence:

>1278_bases
ATGAAAAAAATATTGAATTTTATTGTTGAAATAAATTTGGCAATCATTATTTCCTTATTTACTTCTGATTTTATTCTTTG
GTTTGCAATAATACTTTTATTAATTTTAGCTTGGCATCATATTAATGAATATCGTTTACTCAAATATCTCAATTTAAAGC
AAGATAATAAATTCTCTTTATTACAATTAGGAACATTCTCTCAAACTGAAGCCTACCATCGTCATCAAATTTACAAAGAA
AAATGTGCAAGTTTACGTTTGTTATCTCAAATAAATAAAAATATTAAGTATTTACCAGATGCAATTATTATCTGTCAGCA
TAATGGTAATATTTCTTGGTGTAATTCAATTGCACAACAGATGTTTGATTTTTGTTGGAATAAAAAAGTCCAGAAAAATA
TTTTTGATGTTATTTTTTATGAACAATTTAAACATTATTTTTTCAGTCAAAAAAAAAGACGACCGTTAGTACTATTAACT
TATAATCAACGTTATATTGAGGTGCAGTCGCACGCTTATAATTCTCATATGATTTTAGTTGTCTCTCGAGATATTACAGA
TATGATTCATTTACTTAATTCACGCCAAAAATTCTTGAGTAATATTAATCACGAGCTACGTACTCCATTAACCGTATTAC
AAGGTTACTTAGAAATTCTTGCAGATAATAATATTCAGAACCCTCTACAAAAAAAGGCTATTTTTGCAATGCAAGAGCAA
AGCCAACGAATGGAACATCTATTACAACAATTTAATTTTTTAGCAAAAATAGAAACAACTTCAGATAAGGATTTTCGTAC
ATTTGATATGTCAGCCATGATAAATTCTTTAAGAAAAGATACAGATATATTAAATACTTATAATCATCACATTGAATTTA
TTATTCAGCCTAATATCATTATTTTTGGAAATGAATCTCAACTAAGAAGTGCCGTTTCAAATTTAATTTATAATGCTATT
AAGCATTCTGGTAAACAGTGTCATATTCAAATTAAGTGGGAAACTTGTGAACAGGGTATTAAATTTAACGTGATAGATAA
TGGTGTTGGCATATCGCCACAGCATATTCCACATTTAACAGAACGTTTTTATAGAGTTGATGAATCTCGTAGCCATTTAA
CTGGCGGAAGTGGTTTAGGACTAGCTATTGTGAAGCATACTTTATTACAATATCATTCTCATTTAAATATTGAAAGTACT
GAAACGAAGGGTAGTAGTTTTTCGTTTATCATACCTAAACGCTTTGTCATATCAAAAAATAATAAAGAAATTCAATGA

Upstream 100 bases:

>100_bases
GCCGTTTACGTCGTAATTTAGCCCCTTTTCAATGTGAACATTACATCCAAACAGTTCGAGGATCTGGTTATCGATTTTCT
AGTTATTTACGAGATAAACA

Downstream 100 bases:

>100_bases
TAATACACGTTGCAAGTATTAGCTGACACGGTAGTAACACATCAGAAAATCGAAAATGGTGGGCTAGTGGAGAGCTTAGA
TACATAAAAAACACAGCTTG

Product: phosphate regulon sensor protein PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKKILNFIVEINLAIIISLFTSDFILWFAIILLLILAWHHINEYRLLKYLNLKQDNKFSLLQLGTFSQTEAYHRHQIYKE
KCASLRLLSQINKNIKYLPDAIIICQHNGNISWCNSIAQQMFDFCWNKKVQKNIFDVIFYEQFKHYFFSQKKRRPLVLLT
YNQRYIEVQSHAYNSHMILVVSRDITDMIHLLNSRQKFLSNINHELRTPLTVLQGYLEILADNNIQNPLQKKAIFAMQEQ
SQRMEHLLQQFNFLAKIETTSDKDFRTFDMSAMINSLRKDTDILNTYNHHIEFIIQPNIIIFGNESQLRSAVSNLIYNAI
KHSGKQCHIQIKWETCEQGIKFNVIDNGVGISPQHIPHLTERFYRVDESRSHLTGGSGLGLAIVKHTLLQYHSHLNIEST
ETKGSSFSFIIPKRFVISKNNKEIQ

Sequences:

>Translated_425_residues
MKKILNFIVEINLAIIISLFTSDFILWFAIILLLILAWHHINEYRLLKYLNLKQDNKFSLLQLGTFSQTEAYHRHQIYKE
KCASLRLLSQINKNIKYLPDAIIICQHNGNISWCNSIAQQMFDFCWNKKVQKNIFDVIFYEQFKHYFFSQKKRRPLVLLT
YNQRYIEVQSHAYNSHMILVVSRDITDMIHLLNSRQKFLSNINHELRTPLTVLQGYLEILADNNIQNPLQKKAIFAMQEQ
SQRMEHLLQQFNFLAKIETTSDKDFRTFDMSAMINSLRKDTDILNTYNHHIEFIIQPNIIIFGNESQLRSAVSNLIYNAI
KHSGKQCHIQIKWETCEQGIKFNVIDNGVGISPQHIPHLTERFYRVDESRSHLTGGSGLGLAIVKHTLLQYHSHLNIEST
ETKGSSFSFIIPKRFVISKNNKEIQ
>Mature_425_residues
MKKILNFIVEINLAIIISLFTSDFILWFAIILLLILAWHHINEYRLLKYLNLKQDNKFSLLQLGTFSQTEAYHRHQIYKE
KCASLRLLSQINKNIKYLPDAIIICQHNGNISWCNSIAQQMFDFCWNKKVQKNIFDVIFYEQFKHYFFSQKKRRPLVLLT
YNQRYIEVQSHAYNSHMILVVSRDITDMIHLLNSRQKFLSNINHELRTPLTVLQGYLEILADNNIQNPLQKKAIFAMQEQ
SQRMEHLLQQFNFLAKIETTSDKDFRTFDMSAMINSLRKDTDILNTYNHHIEFIIQPNIIIFGNESQLRSAVSNLIYNAI
KHSGKQCHIQIKWETCEQGIKFNVIDNGVGISPQHIPHLTERFYRVDESRSHLTGGSGLGLAIVKHTLLQYHSHLNIEST
ETKGSSFSFIIPKRFVISKNNKEIQ

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=414, Percent_Identity=38.6473429951691, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1790346, Length=243, Percent_Identity=27.9835390946502, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=28.8793103448276, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788393, Length=224, Percent_Identity=25, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=28.0172413793103, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=26.1061946902655, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789808, Length=279, Percent_Identity=24.0143369175627, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI48994928, Length=342, Percent_Identity=22.8070175438596, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=23.8493723849372, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=22.7906976744186, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790861, Length=212, Percent_Identity=23.1132075471698, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789403, Length=224, Percent_Identity=27.2321428571429, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082128, Length=247, Percent_Identity=21.0526315789474, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49931; Mature: 49931

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILNFIVEINLAIIISLFTSDFILWFAIILLLILAWHHINEYRLLKYLNLKQDNKFSL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEE
LQLGTFSQTEAYHRHQIYKEKCASLRLLSQINKNIKYLPDAIIICQHNGNISWCNSIAQQ
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCCCHHHHHHHHH
MFDFCWNKKVQKNIFDVIFYEQFKHYFFSQKKRRPLVLLTYNQRYIEVQSHAYNSHMILV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCCCEEEEE
VSRDITDMIHLLNSRQKFLSNINHELRTPLTVLQGYLEILADNNIQNPLQKKAIFAMQEQ
EECCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SQRMEHLLQQFNFLAKIETTSDKDFRTFDMSAMINSLRKDTDILNTYNHHIEFIIQPNII
HHHHHHHHHHHHHHEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCEEEEEEECCEE
IFGNESQLRSAVSNLIYNAIKHSGKQCHIQIKWETCEQGIKFNVIDNGVGISPQHIPHLT
EECCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHCCCEEEEEECCCCCCCHHHHHHH
ERFYRVDESRSHLTGGSGLGLAIVKHTLLQYHSHLNIESTETKGSSFSFIIPKRFVISKN
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEECC
NKEIQ
CCCCC
>Mature Secondary Structure
MKKILNFIVEINLAIIISLFTSDFILWFAIILLLILAWHHINEYRLLKYLNLKQDNKFSL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEE
LQLGTFSQTEAYHRHQIYKEKCASLRLLSQINKNIKYLPDAIIICQHNGNISWCNSIAQQ
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCCCHHHHHHHHH
MFDFCWNKKVQKNIFDVIFYEQFKHYFFSQKKRRPLVLLTYNQRYIEVQSHAYNSHMILV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCCCEEEEE
VSRDITDMIHLLNSRQKFLSNINHELRTPLTVLQGYLEILADNNIQNPLQKKAIFAMQEQ
EECCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SQRMEHLLQQFNFLAKIETTSDKDFRTFDMSAMINSLRKDTDILNTYNHHIEFIIQPNII
HHHHHHHHHHHHHHEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCEEEEEEECCEE
IFGNESQLRSAVSNLIYNAIKHSGKQCHIQIKWETCEQGIKFNVIDNGVGISPQHIPHLT
EECCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHCCCEEEEEECCCCCCCHHHHHHH
ERFYRVDESRSHLTGGSGLGLAIVKHTLLQYHSHLNIESTETKGSSFSFIIPKRFVISKN
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEECC
NKEIQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]