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The map label for this gene is lolE [H]

Identifier: 148826796

GI number: 148826796

Start: 32778

End: 34028

Strand: Direct

Name: lolE [H]

Synonym: CGSHiGG_00215

Alternate gene names: 148826796

Gene position: 32778-34028 (Clockwise)

Preceding gene: 148826795

Following gene: 148826797

Centisome position: 1.74

GC content: 37.49

Gene sequence:

>1251_bases
ATGAATACGCCGTTTTTTATTAGCTGGCGTTATCAACGTGGCAAACAAAAAAATCCTTTAGTCGCGTTAATTGCAAAATT
TTCTGCAATTGGTATTGCATTGGGTGTTGCAGTTTTAATTGTTGGTTTAAGTGCGATGAATGGTTTTGAGCGTGAGCTTA
ATCAACGGATTTTGGCAGTCGTGCCGCATATTGAGATTTTTTCTGCGCATCAAGCGAAAGATCCCACAATTCATCATTGG
CAAAATTTAGAAAAACGCCTACAACAAAATCCACAAATTAAAGGAATCTCTCCTTTTGTTAGCTTTACGGCATTGGTAGA
AAATGGCTCAAAATTGAAAGTTGTTCAGGTCAAAGGTGTTGAAAAACAAGCAGAAGATAAGGTAAGTTCAATTGGCAATT
TTGTACAAGAGCAAGGTTGGAACAAATTTGAGAAAGAAGGCGGATTAGTCTTGGGAGCGGGTATTGCTAAAGAACTTGAT
GTAAAAGTAGGGGATTGGATTACCTTGCTTATTTCTCAGCAAAACGGCGATGAACAATTTGCTCAACCAACTCGTGAGCC
AGTGCAAGTTACCGCTATTTTACGCTTAGATGGTCAGCTTGATTATAGTTATGCCTTATTGCCGCTTGCTCAAGCACAAA
CCTTTTTGACTTATCAACCTGATCAAATTACAGGTGTTGAATTGAAATTAGATGATCCTTTTTCTGTGAGAAATCTGGAT
TTATCAATGCTTAATGATTATCCGCAGATGCTATATATGCAAAATTGGATTAGTAAATTTGGTTATATGTATCGCGATAT
TCAGCTTATTAGAACCGTAATGTATATCGCAATGGTGCTTGTGATTGGTGTTGCGTGTTTTAATATTGTTTCTACACTGA
TTATGGCAGTAAAAGATAAGCAAGGCGATATAGCCATTATGCGCACGCTTGGAGCAAATAACGCGTTTATCAAACGTATT
TTTATTTGGTATGGCTTACAAGCAGGAATGAAAGGTTGTTTAATTGGAATTGTGTTAGGCATTATACTTGCATTAAATCT
GACAACTTTTATTCAAGGCATTGAGTGGGTTATCGGTAAGAAATTATTATCGGGCGATGTGTATTTTGTGGATTTCTTGC
CAAGCGAGTTACACTGGTCGGATGTTTTGATGGTTTTAATCGCTGCACTTGCCTTGAGTTTAATAGCAAGCCTTTATCCA
GCAAGCCGAGCTGCTAAATTACAACCTGCACAAGTATTAAGTAGCCATTAA

Upstream 100 bases:

>100_bases
AAAATATCGCCTTTTTATTAGTCACTCACGATATGGGGCTTGCGGAAAAATTATCACGCCGTTTAGTTATGCAAGATGGT
CTTTTGAAGGAGGGGGCGTG

Downstream 100 bases:

>100_bases
TTTCGAGAGTACAGCACAAAAGTGCGGTATTTTTTTATCTTTTATTTACTTAATTATTTCGTTTTATTCAGCTTGCAAGA
GAGTTGTAAAGATAGTTTAA

Product: outer membrane-specific lipoprotein transporter subunit LolE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MNTPFFISWRYQRGKQKNPLVALIAKFSAIGIALGVAVLIVGLSAMNGFERELNQRILAVVPHIEIFSAHQAKDPTIHHW
QNLEKRLQQNPQIKGISPFVSFTALVENGSKLKVVQVKGVEKQAEDKVSSIGNFVQEQGWNKFEKEGGLVLGAGIAKELD
VKVGDWITLLISQQNGDEQFAQPTREPVQVTAILRLDGQLDYSYALLPLAQAQTFLTYQPDQITGVELKLDDPFSVRNLD
LSMLNDYPQMLYMQNWISKFGYMYRDIQLIRTVMYIAMVLVIGVACFNIVSTLIMAVKDKQGDIAIMRTLGANNAFIKRI
FIWYGLQAGMKGCLIGIVLGIILALNLTTFIQGIEWVIGKKLLSGDVYFVDFLPSELHWSDVLMVLIAALALSLIASLYP
ASRAAKLQPAQVLSSH

Sequences:

>Translated_416_residues
MNTPFFISWRYQRGKQKNPLVALIAKFSAIGIALGVAVLIVGLSAMNGFERELNQRILAVVPHIEIFSAHQAKDPTIHHW
QNLEKRLQQNPQIKGISPFVSFTALVENGSKLKVVQVKGVEKQAEDKVSSIGNFVQEQGWNKFEKEGGLVLGAGIAKELD
VKVGDWITLLISQQNGDEQFAQPTREPVQVTAILRLDGQLDYSYALLPLAQAQTFLTYQPDQITGVELKLDDPFSVRNLD
LSMLNDYPQMLYMQNWISKFGYMYRDIQLIRTVMYIAMVLVIGVACFNIVSTLIMAVKDKQGDIAIMRTLGANNAFIKRI
FIWYGLQAGMKGCLIGIVLGIILALNLTTFIQGIEWVIGKKLLSGDVYFVDFLPSELHWSDVLMVLIAALALSLIASLYP
ASRAAKLQPAQVLSSH
>Mature_416_residues
MNTPFFISWRYQRGKQKNPLVALIAKFSAIGIALGVAVLIVGLSAMNGFERELNQRILAVVPHIEIFSAHQAKDPTIHHW
QNLEKRLQQNPQIKGISPFVSFTALVENGSKLKVVQVKGVEKQAEDKVSSIGNFVQEQGWNKFEKEGGLVLGAGIAKELD
VKVGDWITLLISQQNGDEQFAQPTREPVQVTAILRLDGQLDYSYALLPLAQAQTFLTYQPDQITGVELKLDDPFSVRNLD
LSMLNDYPQMLYMQNWISKFGYMYRDIQLIRTVMYIAMVLVIGVACFNIVSTLIMAVKDKQGDIAIMRTLGANNAFIKRI
FIWYGLQAGMKGCLIGIVLGIILALNLTTFIQGIEWVIGKKLLSGDVYFVDFLPSELHWSDVLMVLIAALALSLIASLYP
ASRAAKLQPAQVLSSH

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=417, Percent_Identity=50.8393285371703, Blast_Score=400, Evalue=1e-112,
Organism=Escherichia coli, GI1787360, Length=413, Percent_Identity=28.5714285714286, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46339; Mature: 46339

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPFFISWRYQRGKQKNPLVALIAKFSAIGIALGVAVLIVGLSAMNGFERELNQRILAV
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VPHIEIFSAHQAKDPTIHHWQNLEKRLQQNPQIKGISPFVSFTALVENGSKLKVVQVKGV
CCCHHEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCC
EKQAEDKVSSIGNFVQEQGWNKFEKEGGLVLGAGIAKELDVKVGDWITLLISQQNGDEQF
CHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEECCCCHHCCCCCCCEEEEEEECCCCCHHH
AQPTREPVQVTAILRLDGQLDYSYALLPLAQAQTFLTYQPDQITGVELKLDDPFSVRNLD
HCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCEEEEECCCCEEEEEEEECCCCCCCCCC
LSMLNDYPQMLYMQNWISKFGYMYRDIQLIRTVMYIAMVLVIGVACFNIVSTLIMAVKDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGDIAIMRTLGANNAFIKRIFIWYGLQAGMKGCLIGIVLGIILALNLTTFIQGIEWVIGK
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLSGDVYFVDFLPSELHWSDVLMVLIAALALSLIASLYPASRAAKLQPAQVLSSH
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MNTPFFISWRYQRGKQKNPLVALIAKFSAIGIALGVAVLIVGLSAMNGFERELNQRILAV
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VPHIEIFSAHQAKDPTIHHWQNLEKRLQQNPQIKGISPFVSFTALVENGSKLKVVQVKGV
CCCHHEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCC
EKQAEDKVSSIGNFVQEQGWNKFEKEGGLVLGAGIAKELDVKVGDWITLLISQQNGDEQF
CHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEECCCCHHCCCCCCCEEEEEEECCCCCHHH
AQPTREPVQVTAILRLDGQLDYSYALLPLAQAQTFLTYQPDQITGVELKLDDPFSVRNLD
HCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCEEEEECCCCEEEEEEEECCCCCCCCCC
LSMLNDYPQMLYMQNWISKFGYMYRDIQLIRTVMYIAMVLVIGVACFNIVSTLIMAVKDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGDIAIMRTLGANNAFIKRIFIWYGLQAGMKGCLIGIVLGIILALNLTTFIQGIEWVIGK
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLSGDVYFVDFLPSELHWSDVLMVLIAALALSLIASLYPASRAAKLQPAQVLSSH
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]