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The map label for this gene is pgi [H]

Identifier: 148826763

GI number: 148826763

Start: 2916

End: 4565

Strand: Reverse

Name: pgi [H]

Synonym: CGSHiGG_00035

Alternate gene names: 148826763

Gene position: 4565-2916 (Counterclockwise)

Preceding gene: 148826764

Following gene: 148826762

Centisome position: 0.24

GC content: 37.21

Gene sequence:

>1650_bases
ATGAAAAATATTAACCCAACTCACACCCAAGCGTGGAAATCTCTCGAAGCACATAAAGCTGAATTATCAAACACCACCAT
CCAAGATTTATTTAAACAAGAAAAAAATCGTTTTGACGATTATTCTTTAACATTCAATAACCAAATTCTTGTCGATTTTT
CCAAAAACAACATCAATCAAACAACCCTTTCACATCTTCGCCAACTTGCTCAAGAATGCGCGCTTGATAGTGCAAAAGAA
GCGATGTTTACTGGCGAAAAAATCAATCGTACAGAAAATCGTGCCGTGCTGCATACTGCACTTCGCAATCGCACTAATAC
GCCAGTACTTGTTGATGGTAAAGATGTTATGCCTGAAGTCAATGCTGTGTTAGCTAAAATGAAAGATTTCTGTCAGCGTA
TTATTTCTGGCGAATGGAAAGGCTATACAGGCAAAGCCATTACGGATGTTGTGAATATTGGTATTGGTGGCTCTGACTTA
GGCCCTTATACGGTAACCGAAGCGCTTCGCCCATATAAAAATCACTTAAATATGCACTTTGTTTCAAATGTCGATGGTAC
ACACATTGCAGAAACCTTAAAAAAAGTCAATCCAGAAACCACTCTTTTCTTAGTGGCATCTAAGACTTTTACAACTCAAG
AAACCATGACAAATGCGCAAAGTGCGCGTGATTGGTTACTAAAAGCAGCGAAAGATGAAAGTGCAGTTGCAAAACATTTT
GCAGCATTATCAACCAATGCTAAAGATGTAGAAAAATTTGGCATTGATACCAATAACATGTTTGAATTTTGGGATTGGGT
TGGCGGTCGTTACTCTTTATGGTCAGCTATTGGTCTTTCAATTGCACTATCAATTGGCTTTGAAAACTTTGAAGCGTTAT
TAAATGGCGCGCATGAAATGGATAAACATTTCCGCTCTACTCCAATCGAACAAAATATCCCAACTACTTTAGCATTAGTT
GGTTTATGGAATACCAATTTCCTTGGTGCACAAACAGAAGCGATCTTACCTTATGATCAATATTTACATCGCTTCGCAGC
TTATTTTCAACAAGGTAATATGGAATCAAATGGTAAATATGTGGATCGTGATGGCAATGTCATTAACAATTATCAAACTG
GCCCTATCATTTGGGGAGAACCAGGTACAAATGGACAACACGCGTTCTATCAATTAATTCATCAAGGCACCACTTTAATT
CCTTGTGATTTTATCGCACCAGCCCAAAGCCACAATCCATTGGCGGATCATCACAATAAATTGCTTTCAAACTTCTTTGC
ACAAACAGAAGCATTAGCATTCGGAAAAACAAAAGAAGAAGTCGAGGCTGAATTTATAAAAGCGGGTAAATCTTTAGATG
ATGTAAAAAATATCGTTCCATTTAAAGTATTTACGGGTAATAAGCCAACTAATTCTATTCTCGTTCAAAAAATCACGCCA
TTTACCTTGGGTGCATTAATTGCTATGTATGAACACAAAATCTTCGTACAAGGTGTGATTTTTAATATCTTTAGCTTCGA
TCAATGGGGCGTAGAGCTAGGCAAACAACTTGCAAACAGAATTCTTCCTGAATTAACCGATTCTGAAAAAGTCGCAAGCC
ACGATAGTTCAACAAATGGATTAATCAATCAATTTAAAACATGGCGTTAA

Upstream 100 bases:

>100_bases
TTAATCACTGCATTTTTTGAACAGAGGGAGTCATTCTCCCTAATAAAAATTCCAGAAAGTGCGGTTAAAATTTCAATTAT
TTTTAATGAAAGGAAATACC

Downstream 100 bases:

>100_bases
TTATTTGGATTTGAATAATTCTAGAGCTGTCACAGATAACGACTAAAAACTCTATTTAGGTTAAGATAATCAAATGAGAG
AAAGTCGCTTAAGTCAATAT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKNINPTHTQAWKSLEAHKAELSNTTIQDLFKQEKNRFDDYSLTFNNQILVDFSKNNINQTTLSHLRQLAQECALDSAKE
AMFTGEKINRTENRAVLHTALRNRTNTPVLVDGKDVMPEVNAVLAKMKDFCQRIISGEWKGYTGKAITDVVNIGIGGSDL
GPYTVTEALRPYKNHLNMHFVSNVDGTHIAETLKKVNPETTLFLVASKTFTTQETMTNAQSARDWLLKAAKDESAVAKHF
AALSTNAKDVEKFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSIGFENFEALLNGAHEMDKHFRSTPIEQNIPTTLALV
GLWNTNFLGAQTEAILPYDQYLHRFAAYFQQGNMESNGKYVDRDGNVINNYQTGPIIWGEPGTNGQHAFYQLIHQGTTLI
PCDFIAPAQSHNPLADHHNKLLSNFFAQTEALAFGKTKEEVEAEFIKAGKSLDDVKNIVPFKVFTGNKPTNSILVQKITP
FTLGALIAMYEHKIFVQGVIFNIFSFDQWGVELGKQLANRILPELTDSEKVASHDSSTNGLINQFKTWR

Sequences:

>Translated_549_residues
MKNINPTHTQAWKSLEAHKAELSNTTIQDLFKQEKNRFDDYSLTFNNQILVDFSKNNINQTTLSHLRQLAQECALDSAKE
AMFTGEKINRTENRAVLHTALRNRTNTPVLVDGKDVMPEVNAVLAKMKDFCQRIISGEWKGYTGKAITDVVNIGIGGSDL
GPYTVTEALRPYKNHLNMHFVSNVDGTHIAETLKKVNPETTLFLVASKTFTTQETMTNAQSARDWLLKAAKDESAVAKHF
AALSTNAKDVEKFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSIGFENFEALLNGAHEMDKHFRSTPIEQNIPTTLALV
GLWNTNFLGAQTEAILPYDQYLHRFAAYFQQGNMESNGKYVDRDGNVINNYQTGPIIWGEPGTNGQHAFYQLIHQGTTLI
PCDFIAPAQSHNPLADHHNKLLSNFFAQTEALAFGKTKEEVEAEFIKAGKSLDDVKNIVPFKVFTGNKPTNSILVQKITP
FTLGALIAMYEHKIFVQGVIFNIFSFDQWGVELGKQLANRILPELTDSEKVASHDSSTNGLINQFKTWR
>Mature_549_residues
MKNINPTHTQAWKSLEAHKAELSNTTIQDLFKQEKNRFDDYSLTFNNQILVDFSKNNINQTTLSHLRQLAQECALDSAKE
AMFTGEKINRTENRAVLHTALRNRTNTPVLVDGKDVMPEVNAVLAKMKDFCQRIISGEWKGYTGKAITDVVNIGIGGSDL
GPYTVTEALRPYKNHLNMHFVSNVDGTHIAETLKKVNPETTLFLVASKTFTTQETMTNAQSARDWLLKAAKDESAVAKHF
AALSTNAKDVEKFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSIGFENFEALLNGAHEMDKHFRSTPIEQNIPTTLALV
GLWNTNFLGAQTEAILPYDQYLHRFAAYFQQGNMESNGKYVDRDGNVINNYQTGPIIWGEPGTNGQHAFYQLIHQGTTLI
PCDFIAPAQSHNPLADHHNKLLSNFFAQTEALAFGKTKEEVEAEFIKAGKSLDDVKNIVPFKVFTGNKPTNSILVQKITP
FTLGALIAMYEHKIFVQGVIFNIFSFDQWGVELGKQLANRILPELTDSEKVASHDSSTNGLINQFKTWR

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=546, Percent_Identity=64.2857142857143, Blast_Score=736, Evalue=0.0,
Organism=Homo sapiens, GI296080693, Length=538, Percent_Identity=60.5947955390335, Blast_Score=672, Evalue=0.0,
Organism=Escherichia coli, GI1790457, Length=549, Percent_Identity=76.8670309653916, Blast_Score=903, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71996708, Length=529, Percent_Identity=62.5708884688091, Blast_Score=691, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71996703, Length=529, Percent_Identity=62.5708884688091, Blast_Score=690, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319673, Length=550, Percent_Identity=58.7272727272727, Blast_Score=645, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651916, Length=541, Percent_Identity=65.4343807763401, Blast_Score=726, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651914, Length=541, Percent_Identity=65.4343807763401, Blast_Score=726, Evalue=0.0,
Organism=Drosophila melanogaster, GI17737445, Length=541, Percent_Identity=65.4343807763401, Blast_Score=726, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 61561; Mature: 61561

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNINPTHTQAWKSLEAHKAELSNTTIQDLFKQEKNRFDDYSLTFNNQILVDFSKNNINQ
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCCH
TTLSHLRQLAQECALDSAKEAMFTGEKINRTENRAVLHTALRNRTNTPVLVDGKDVMPEV
HHHHHHHHHHHHHCCCHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHH
NAVLAKMKDFCQRIISGEWKGYTGKAITDVVNIGIGGSDLGPYTVTEALRPYKNHLNMHF
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEE
VSNVDGTHIAETLKKVNPETTLFLVASKTFTTQETMTNAQSARDWLLKAAKDESAVAKHF
ECCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AALSTNAKDVEKFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSIGFENFEALLNGAHEM
HHHCCCHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHEEECHHHHHHHHCCHHHH
DKHFRSTPIEQNIPTTLALVGLWNTNFLGAQTEAILPYDQYLHRFAAYFQQGNMESNGKY
HHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCEE
VDRDGNVINNYQTGPIIWGEPGTNGQHAFYQLIHQGTTLIPCDFIAPAQSHNPLADHHNK
ECCCCCEECCCCCCCEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHH
LLSNFFAQTEALAFGKTKEEVEAEFIKAGKSLDDVKNIVPFKVFTGNKPTNSILVQKITP
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCCCCEEEECCCH
FTLGALIAMYEHKIFVQGVIFNIFSFDQWGVELGKQLANRILPELTDSEKVASHDSSTNG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCH
LINQFKTWR
HHHHHCCCC
>Mature Secondary Structure
MKNINPTHTQAWKSLEAHKAELSNTTIQDLFKQEKNRFDDYSLTFNNQILVDFSKNNINQ
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCCH
TTLSHLRQLAQECALDSAKEAMFTGEKINRTENRAVLHTALRNRTNTPVLVDGKDVMPEV
HHHHHHHHHHHHHCCCHHHHHHHCCHHHCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHH
NAVLAKMKDFCQRIISGEWKGYTGKAITDVVNIGIGGSDLGPYTVTEALRPYKNHLNMHF
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEE
VSNVDGTHIAETLKKVNPETTLFLVASKTFTTQETMTNAQSARDWLLKAAKDESAVAKHF
ECCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AALSTNAKDVEKFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSIGFENFEALLNGAHEM
HHHCCCHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHEEECHHHHHHHHCCHHHH
DKHFRSTPIEQNIPTTLALVGLWNTNFLGAQTEAILPYDQYLHRFAAYFQQGNMESNGKY
HHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCEE
VDRDGNVINNYQTGPIIWGEPGTNGQHAFYQLIHQGTTLIPCDFIAPAQSHNPLADHHNK
ECCCCCEECCCCCCCEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHH
LLSNFFAQTEALAFGKTKEEVEAEFIKAGKSLDDVKNIVPFKVFTGNKPTNSILVQKITP
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCCCCEEEECCCH
FTLGALIAMYEHKIFVQGVIFNIFSFDQWGVELGKQLANRILPELTDSEKVASHDSSTNG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCH
LINQFKTWR
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA