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The map label for this gene is trpS [H]

Identifier: 148826730

GI number: 148826730

Start: 1782884

End: 1783888

Strand: Direct

Name: trpS [H]

Synonym: CGSHiEE_09035

Alternate gene names: 148826730

Gene position: 1782884-1783888 (Clockwise)

Preceding gene: 148826724

Following gene: 148826731

Centisome position: 98.34

GC content: 38.91

Gene sequence:

>1005_bases
ATGGCAAAACCAATTGTTTTTAGTGGCGTGCAGCCTTCTGGTGAATTAACTATCGGAAATTATTTGGGTGCGTTGCGTAA
CTGGGTGAAAATGCAAGAGGATTATGAATGTATTTTCTGCGTAGTTGATTTACATGCGATCACTGTGCGTCAAGATCCTG
TTGCCCTTCGTAAAGCAACGCTTGATGTGCTTGCACTTTATTTAGCGTGCGGAATTGATCCAAATAAAAGTACTATTTTT
GTTCAATCTCACGTTCCAGAACACACGCAATTAAGCTGGGTGTTAAACTGTTACACCTATTTCGGTGAAATGAGCCGAAT
GACGCAATTCAAAGATAAATCAGCGCGTTATGCAGAAAATATTAACGTGGGTTTGTTTGATTATCCTGTGTTAATGGCGG
CGGATATTTTACTTTATCAAGCAAAAAGCGTGCCTGTTGGTGATGACCAAAAACAACACTTAGAAATTACGCGTGATATT
GCAAACCGCTTTAATGCGCTTTATGGCAATATTTTCACTATTCCTGAAATTTTCATTGGAAAAGCAGGTGCGCGTATTAT
GTCATTGCAAGATCCTGAAAAGAAAATGTCAAAATCAGATGATAACCGCAACAACGTGGTGACACTTTTGGAAGATCCAA
AATCTGTGGCGAAAAAAATTAAACGTGCCGTAACGGATTCAGATGAGCCGCCTGTTGTTCGTTATGATGTGCAAAATAAA
GCGGGGGTATCTAATCTTTTAGATATTCTTTCTGCGGTTACAGATAAGCCAATAGCTGATCTTGAAAAAGAATTTGAAGG
TAAAATGTACGGACATTTAAAAACTGCAGTAGCGGATGAAGTCACAACCTTACTTACTGGTTTACAAGATCGTTTCCATC
GATATCGTAATGATGAAACTTTATTAGATAATATCTTACGACAAGGTGCGGAAAAAGCTCGTGCAAAAGCACAAGAAACC
TTGGCGAAAGTGTATGAAGCAGTGGGTTTTGTCGCTGCAAAATAA

Upstream 100 bases:

>100_bases
AAATATAGCATTTTTAACCTAGCTTTTGAACTCGAACATTAAAAAAGCCTAGAGTTTCTGATATGATGTGCGAACAGTTT
TAAGGTATTAAGGATTGATT

Downstream 100 bases:

>100_bases
TCTGAATAAAAGGATAATATTATGGCAATTCAAACTGAAAAACCGATTGAATGTATAGGTTGAACACATTTGATATGAAA
TCACTTTTCGATAATCGTGA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAKPIVFSGVQPSGELTIGNYLGALRNWVKMQEDYECIFCVVDLHAITVRQDPVALRKATLDVLALYLACGIDPNKSTIF
VQSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAENINVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDI
ANRFNALYGNIFTIPEIFIGKAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEPPVVRYDVQNK
AGVSNLLDILSAVTDKPIADLEKEFEGKMYGHLKTAVADEVTTLLTGLQDRFHRYRNDETLLDNILRQGAEKARAKAQET
LAKVYEAVGFVAAK

Sequences:

>Translated_334_residues
MAKPIVFSGVQPSGELTIGNYLGALRNWVKMQEDYECIFCVVDLHAITVRQDPVALRKATLDVLALYLACGIDPNKSTIF
VQSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAENINVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDI
ANRFNALYGNIFTIPEIFIGKAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEPPVVRYDVQNK
AGVSNLLDILSAVTDKPIADLEKEFEGKMYGHLKTAVADEVTTLLTGLQDRFHRYRNDETLLDNILRQGAEKARAKAQET
LAKVYEAVGFVAAK
>Mature_333_residues
AKPIVFSGVQPSGELTIGNYLGALRNWVKMQEDYECIFCVVDLHAITVRQDPVALRKATLDVLALYLACGIDPNKSTIFV
QSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAENINVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDIA
NRFNALYGNIFTIPEIFIGKAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEPPVVRYDVQNKA
GVSNLLDILSAVTDKPIADLEKEFEGKMYGHLKTAVADEVTTLLTGLQDRFHRYRNDETLLDNILRQGAEKARAKAQETL
AKVYEAVGFVAAK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=41.0876132930514, Blast_Score=272, Evalue=3e-73,
Organism=Homo sapiens, GI41352700, Length=176, Percent_Identity=51.1363636363636, Blast_Score=203, Evalue=1e-52,
Organism=Escherichia coli, GI1789786, Length=332, Percent_Identity=78.6144578313253, Blast_Score=558, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71982800, Length=334, Percent_Identity=35.9281437125749, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI71982793, Length=334, Percent_Identity=35.9281437125749, Blast_Score=213, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=41.1594202898551, Blast_Score=251, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24666151, Length=329, Percent_Identity=40.7294832826748, Blast_Score=252, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37424; Mature: 37293

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPIVFSGVQPSGELTIGNYLGALRNWVKMQEDYECIFCVVDLHAITVRQDPVALRKAT
CCCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHHHEEECCCCHHHHHHH
LDVLALYLACGIDPNKSTIFVQSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAEN
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
INVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDIANRFNALYGNIFTIPEIFIG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHC
KAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEPPVVRYDVQNK
CCCCEEECCCCHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCC
AGVSNLLDILSAVTDKPIADLEKEFEGKMYGHLKTAVADEVTTLLTGLQDRFHRYRNDET
CCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLDNILRQGAEKARAKAQETLAKVYEAVGFVAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKPIVFSGVQPSGELTIGNYLGALRNWVKMQEDYECIFCVVDLHAITVRQDPVALRKAT
CCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHHHEEECCCCHHHHHHH
LDVLALYLACGIDPNKSTIFVQSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAEN
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
INVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDIANRFNALYGNIFTIPEIFIG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHC
KAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEPPVVRYDVQNK
CCCCEEECCCCHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCC
AGVSNLLDILSAVTDKPIADLEKEFEGKMYGHLKTAVADEVTTLLTGLQDRFHRYRNDET
CCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLDNILRQGAEKARAKAQETLAKVYEAVGFVAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]