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The map label for this gene is tag [H]

Identifier: 148826711

GI number: 148826711

Start: 1762889

End: 1763452

Strand: Direct

Name: tag [H]

Synonym: CGSHiEE_08930

Alternate gene names: 148826711

Gene position: 1762889-1763452 (Clockwise)

Preceding gene: 148826710

Following gene: 148826713

Centisome position: 97.23

GC content: 39.18

Gene sequence:

>564_bases
ATGCAACAAATAACCAGATGCCCTTGGGTGGGTGAACAACCTATTTATATTGATTATCATGACAAGGAATGGGGAAAGCC
TGAATTCGACAGCCAAAAGCTATTTGAAAAAATTTGTTTGGAAGGGCAGCAAGCGGGGCTTTCGTGGATTACGGTTTTGA
AAAAACGTGAATCTTACCGTGAGGCTTTTCATCAATTTGATCCGAAAAAAATCGCTAAAATGACCGCACTTGATATTGAT
GCTTGTATGCAAAATACAGGATTAATTCGCCATCGAGCCAAGTTAGAAGCCATTGTCAAAAATGCGAAAGCTTATTTGGA
GATGGAAAAGTGCGGTGAAAATTTCAGTGATTTTATTTGGTCATTTGTGAATCATAAACCGATTGTCAATGATGTGCCTG
ATTTGCGATCTGTACCTGCTAAAACAGAAGCATCGAAAACACTTTCTAAAGCCTTAAAAAAACGTGGTTTCGTCTTTGTT
GGCGAAACCACGTGTTATGCGTTTATGCAGTCTATGGGGTTAGTGGACGATCATTTAAATGATTGTCCTTGCAAAACTCG
CTAG

Upstream 100 bases:

>100_bases
AAGCCTCAATGAAACTCACTGAAGCTATGACGCCGACCAAGCACCCTCGATCCACTTGGCTCGGAATATATCAAAACGTT
TTATTTTGTCAAGTTTTAAT

Downstream 100 bases:

>100_bases
TGTTTATGCTGATCTCGCTCCCATAAATCGGCGTATTTTACAAAGGTTGAATGCGCTGATAACACCGCTAATAAAAATCC
TTGTTTACCATCTAAAAAAC

Product: DNA-3-methyladenine glycosylase

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosidase; TAG [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MQQITRCPWVGEQPIYIDYHDKEWGKPEFDSQKLFEKICLEGQQAGLSWITVLKKRESYREAFHQFDPKKIAKMTALDID
ACMQNTGLIRHRAKLEAIVKNAKAYLEMEKCGENFSDFIWSFVNHKPIVNDVPDLRSVPAKTEASKTLSKALKKRGFVFV
GETTCYAFMQSMGLVDDHLNDCPCKTR

Sequences:

>Translated_187_residues
MQQITRCPWVGEQPIYIDYHDKEWGKPEFDSQKLFEKICLEGQQAGLSWITVLKKRESYREAFHQFDPKKIAKMTALDID
ACMQNTGLIRHRAKLEAIVKNAKAYLEMEKCGENFSDFIWSFVNHKPIVNDVPDLRSVPAKTEASKTLSKALKKRGFVFV
GETTCYAFMQSMGLVDDHLNDCPCKTR
>Mature_187_residues
MQQITRCPWVGEQPIYIDYHDKEWGKPEFDSQKLFEKICLEGQQAGLSWITVLKKRESYREAFHQFDPKKIAKMTALDID
ACMQNTGLIRHRAKLEAIVKNAKAYLEMEKCGENFSDFIWSFVNHKPIVNDVPDLRSVPAKTEASKTLSKALKKRGFVFV
GETTCYAFMQSMGLVDDHLNDCPCKTR

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=181, Percent_Identity=62.4309392265193, Blast_Score=250, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 21571; Mature: 21571

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQITRCPWVGEQPIYIDYHDKEWGKPEFDSQKLFEKICLEGQQAGLSWITVLKKRESYR
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EAFHQFDPKKIAKMTALDIDACMQNTGLIRHRAKLEAIVKNAKAYLEMEKCGENFSDFIW
HHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SFVNHKPIVNDVPDLRSVPAKTEASKTLSKALKKRGFVFVGETTCYAFMQSMGLVDDHLN
HHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCHHHCCC
DCPCKTR
CCCCCCC
>Mature Secondary Structure
MQQITRCPWVGEQPIYIDYHDKEWGKPEFDSQKLFEKICLEGQQAGLSWITVLKKRESYR
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EAFHQFDPKKIAKMTALDIDACMQNTGLIRHRAKLEAIVKNAKAYLEMEKCGENFSDFIW
HHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SFVNHKPIVNDVPDLRSVPAKTEASKTLSKALKKRGFVFVGETTCYAFMQSMGLVDDHLN
HHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCHHHCCC
DCPCKTR
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]