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The map label for this gene is glpA [H]

Identifier: 148826678

GI number: 148826678

Start: 1732092

End: 1733783

Strand: Direct

Name: glpA [H]

Synonym: CGSHiEE_08755

Alternate gene names: 148826678

Gene position: 1732092-1733783 (Clockwise)

Preceding gene: 148826674

Following gene: 148826679

Centisome position: 95.54

GC content: 43.85

Gene sequence:

>1692_bases
ATGGGATTATCGCCTAGTATCTATAAAGATGTTGGAGATCTTTCGCCACTTAGCACTGATGTGATCATTATCGGTGGTGG
TGCAACAGGAGCAGGTATTGCGCGCGATTGCGCACTTCGTGGCATTGATTGTATTTTATTGGAACGTCGAGATATTGCGA
CAGGTGCCACAGGACGTAACCACGGATTATTACACAGTGGTGCGCGTTATGCCGTGAACGACCAAGAATCTGCTGAAGAA
TGTATTAAAGAAAACCGCATTTTGCGCAAAATTGCGCGTCATTGCGTAGATGAAACGGAAGGCTTATTTATCACTTTGCC
TGAAGATTCTCTCGACTATCAAAAAACTTTCCTTGAGAGCTGTGCAAAATCTGGAATTGATGCGCAAGCCATTGATCCTG
AACTAGCTAAAATTATGGAGCCTTCAGTAAACCCTGATTTAGTGGGTGCTGTTGTTGTGCCAGATGGTTCTATTGACCCA
TTCCGTTTAACCGCCTCTAATATGATGGATGCGACAGAAAATGGTGCAAAAATGTTCACTTATTGCGAAGTAAAAAATTT
GATTCGTGAAGGTGGAAAAGTGATTGGTGTGAATGTGTACGATCACAAAAATCGTAGAGAACGCCAATTTTTTGCACCGC
TTGTTGTGAATGCTGGTGGTATTTGGGGGCAAGGGATTGCGGAATATGCCGATCTCAAAATCAAAATGTTCCCTGCAAAA
GGCGCATTGCTCGTAATGGGCCATCGCATTAATAAACTTGTCATTAACCGCTGCCGTAAACCTGCTGATGCGGATATTCT
CGTACCTGGCGATACAATTTGTGTTATCGGAACAACATCTAGCCGCATTCCTTATGATCAAATTGATAATATGGAAGTAA
CGCCAGAGGAAGTGGATATTCTTTTCCGTGAGGGAGAAAAACTTGCACCGAGCTTACGTCATACTCGCGTATTACGTGCT
TATGCTGGGGTGCGACCATTAGTTGCGAGTGATGATGATCCATCAGGTCGAAATGTGAGTCGTGGTATTGTACTACTTGA
CCACGCAGAGCGTGATGGCTTAGATGGCTTTATTACAATCACTGGCGGTAAGTTAATGACTTATCGTTTAATGGCTGAAT
GGGCGACTGACCTTGTTTGTAAAAAACTCAATAAAACGGCTCGTTGTGTTACTGCTGAACAGGCTCTACCAGGTTCGACT
GAAAGTCGCCAAGAGACCAATCAAAAAGTTATTTCATTACCAAGTACTATTCGTTATTCTGCTGTGTATCGTCATGGTTC
ACGTGCTACTCGTTTGCTTGAAAAAGAACGTTTAGATCGTTCAATGGTTTGTGAATGCGAAGCGGTGACGGCGGGGGAAG
TTCGTTACGCTGTTGATGAACTGGATGTAAATAATCTCGTCGATTTACGTCGTCGCTCCCGAGTTGGAATGGGAACTTGT
CAAGCTGAACTCTGTGCTTGTCGTGCTGCAGGACTAATGAATCGTTTTGAAGTGGCAACACCACGTCAATCAACTACTCA
ACTTTCTGCTTTTATGGAAGAACGCTGGCGCGGTATTGAGCCGATTGCTTGGGGTGAAGCTATTCGCGAAGCCGAATTTA
CCTCTTGGATGTATGGTAGCGTATTAGGTTTAAATGATGTGAAACCGCTTGATGAACAAGCACAACAAGGGACGGATAGC
AATGAATTTTGA

Upstream 100 bases:

>100_bases
TTCTTTTACGCTCAAAATGTTGTTAATTTTGCCGCACTTCTCTACAATGAACACACTTTTTATATTATTTTTATTACATT
TTGGGAATCGGGGGTAAACA

Downstream 100 bases:

>100_bases
TGTAGCCATTATTGGCGGTGGTTTGGCAGGTTTAACCTGCGGCATCGCCCTTCAACAACGGGGCAAACGTTGCGTGATTA
TCAACAACGGTCAAGCAGCC

Product: sn-glycerol-3-phosphate dehydrogenase subunit A

Products: NA

Alternate protein names: G-3-P dehydrogenase [H]

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MGLSPSIYKDVGDLSPLSTDVIIIGGGATGAGIARDCALRGIDCILLERRDIATGATGRNHGLLHSGARYAVNDQESAEE
CIKENRILRKIARHCVDETEGLFITLPEDSLDYQKTFLESCAKSGIDAQAIDPELAKIMEPSVNPDLVGAVVVPDGSIDP
FRLTASNMMDATENGAKMFTYCEVKNLIREGGKVIGVNVYDHKNRRERQFFAPLVVNAGGIWGQGIAEYADLKIKMFPAK
GALLVMGHRINKLVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDILFREGEKLAPSLRHTRVLRA
YAGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDLVCKKLNKTARCVTAEQALPGST
ESRQETNQKVISLPSTIRYSAVYRHGSRATRLLEKERLDRSMVCECEAVTAGEVRYAVDELDVNNLVDLRRRSRVGMGTC
QAELCACRAAGLMNRFEVATPRQSTTQLSAFMEERWRGIEPIAWGEAIREAEFTSWMYGSVLGLNDVKPLDEQAQQGTDS
NEF

Sequences:

>Translated_563_residues
MGLSPSIYKDVGDLSPLSTDVIIIGGGATGAGIARDCALRGIDCILLERRDIATGATGRNHGLLHSGARYAVNDQESAEE
CIKENRILRKIARHCVDETEGLFITLPEDSLDYQKTFLESCAKSGIDAQAIDPELAKIMEPSVNPDLVGAVVVPDGSIDP
FRLTASNMMDATENGAKMFTYCEVKNLIREGGKVIGVNVYDHKNRRERQFFAPLVVNAGGIWGQGIAEYADLKIKMFPAK
GALLVMGHRINKLVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDILFREGEKLAPSLRHTRVLRA
YAGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDLVCKKLNKTARCVTAEQALPGST
ESRQETNQKVISLPSTIRYSAVYRHGSRATRLLEKERLDRSMVCECEAVTAGEVRYAVDELDVNNLVDLRRRSRVGMGTC
QAELCACRAAGLMNRFEVATPRQSTTQLSAFMEERWRGIEPIAWGEAIREAEFTSWMYGSVLGLNDVKPLDEQAQQGTDS
NEF
>Mature_562_residues
GLSPSIYKDVGDLSPLSTDVIIIGGGATGAGIARDCALRGIDCILLERRDIATGATGRNHGLLHSGARYAVNDQESAEEC
IKENRILRKIARHCVDETEGLFITLPEDSLDYQKTFLESCAKSGIDAQAIDPELAKIMEPSVNPDLVGAVVVPDGSIDPF
RLTASNMMDATENGAKMFTYCEVKNLIREGGKVIGVNVYDHKNRRERQFFAPLVVNAGGIWGQGIAEYADLKIKMFPAKG
ALLVMGHRINKLVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDILFREGEKLAPSLRHTRVLRAY
AGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDLVCKKLNKTARCVTAEQALPGSTE
SRQETNQKVISLPSTIRYSAVYRHGSRATRLLEKERLDRSMVCECEAVTAGEVRYAVDELDVNNLVDLRRRSRVGMGTCQ
AELCACRAAGLMNRFEVATPRQSTTQLSAFMEERWRGIEPIAWGEAIREAEFTSWMYGSVLGLNDVKPLDEQAQQGTDSN
EF

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Fumarate Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=524, Percent_Identity=26.3358778625954, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI285002231, Length=524, Percent_Identity=26.3358778625954, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI197927446, Length=289, Percent_Identity=25.2595155709343, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI21361378, Length=289, Percent_Identity=25.2595155709343, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1788574, Length=527, Percent_Identity=70.9677419354839, Blast_Score=750, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17509253, Length=412, Percent_Identity=28.6407766990291, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115534726, Length=419, Percent_Identity=26.0143198090692, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI161077125, Length=403, Percent_Identity=28.0397022332506, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24653942, Length=403, Percent_Identity=28.0397022332506, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24653944, Length=403, Percent_Identity=28.0397022332506, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20130025, Length=403, Percent_Identity=28.0397022332506, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20130091, Length=245, Percent_Identity=31.0204081632653, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR006076
- InterPro:   IPR017752
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO; PF04324 Fer2_BFD [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 61918; Mature: 61787

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSPSIYKDVGDLSPLSTDVIIIGGGATGAGIARDCALRGIDCILLERRDIATGATGRN
CCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCC
HGLLHSGARYAVNDQESAEECIKENRILRKIARHCVDETEGLFITLPEDSLDYQKTFLES
CCCEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
CAKSGIDAQAIDPELAKIMEPSVNPDLVGAVVVPDGSIDPFRLTASNMMDATENGAKMFT
HHHCCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHCCCCCCEEEE
YCEVKNLIREGGKVIGVNVYDHKNRRERQFFAPLVVNAGGIWGQGIAEYADLKIKMFPAK
HHHHHHHHHCCCEEEEEEEECCCCCHHHHHHCCEEEECCCCCCCCHHHHHCEEEEEECCC
GALLVMGHRINKLVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDI
CEEEEECCHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCHHHCCCCCCCHHHHHH
LFREGEKLAPSLRHTRVLRAYAGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITI
HHHCCCHHCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
TGGKLMTYRLMAEWATDLVCKKLNKTARCVTAEQALPGSTESRQETNQKVISLPSTIRYS
ECCCEEHHHHHHHHHHHHHHHHHCHHHHEEEHHHCCCCCCHHHHHHHHHEEECCCHHHHH
AVYRHGSRATRLLEKERLDRSMVCECEAVTAGEVRYAVDELDVNNLVDLRRRSRVGMGTC
HHHHCCHHHHHHHHHHHCCHHHEEEECCCCCCCEEEHHHHCCHHHHHHHHHHHCCCCCHH
QAELCACRAAGLMNRFEVATPRQSTTQLSAFMEERWRGIEPIAWGEAIREAEFTSWMYGS
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHC
VLGLNDVKPLDEQAQQGTDSNEF
EECCCCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure 
GLSPSIYKDVGDLSPLSTDVIIIGGGATGAGIARDCALRGIDCILLERRDIATGATGRN
CCCCHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCC
HGLLHSGARYAVNDQESAEECIKENRILRKIARHCVDETEGLFITLPEDSLDYQKTFLES
CCCEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
CAKSGIDAQAIDPELAKIMEPSVNPDLVGAVVVPDGSIDPFRLTASNMMDATENGAKMFT
HHHCCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHCCCCCCEEEE
YCEVKNLIREGGKVIGVNVYDHKNRRERQFFAPLVVNAGGIWGQGIAEYADLKIKMFPAK
HHHHHHHHHCCCEEEEEEEECCCCCHHHHHHCCEEEECCCCCCCCHHHHHCEEEEEECCC
GALLVMGHRINKLVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDI
CEEEEECCHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCHHHCCCCCCCHHHHHH
LFREGEKLAPSLRHTRVLRAYAGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITI
HHHCCCHHCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
TGGKLMTYRLMAEWATDLVCKKLNKTARCVTAEQALPGSTESRQETNQKVISLPSTIRYS
ECCCEEHHHHHHHHHHHHHHHHHCHHHHEEEHHHCCCCCCHHHHHHHHHEEECCCHHHHH
AVYRHGSRATRLLEKERLDRSMVCECEAVTAGEVRYAVDELDVNNLVDLRRRSRVGMGTC
HHHHCCHHHHHHHHHHHCCHHHEEEECCCCCCCEEEHHHHCCHHHHHHHHHHHCCCCCHH
QAELCACRAAGLMNRFEVATPRQSTTQLSAFMEERWRGIEPIAWGEAIREAEFTSWMYGS
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHC
VLGLNDVKPLDEQAQQGTDSNEF
EECCCCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]