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The map label for this gene is ppx [H]

Identifier: 148826661

GI number: 148826661

Start: 1714892

End: 1715869

Strand: Direct

Name: ppx [H]

Synonym: CGSHiEE_08660

Alternate gene names: 148826661

Gene position: 1714892-1715869 (Clockwise)

Preceding gene: 148826660

Following gene: 148826667

Centisome position: 94.59

GC content: 42.02

Gene sequence:

>978_bases
ATGAATGACGCTATTTTAGAACCCAAGCATCGTGGCAATGTACGTGAAATTGCCGCGATTGATCTTGGCTCAAACAGCTT
TCATATGATTGTTGCACGCATTGTAAACGGCTCAATCCAAGTGCTTTTGCGCTTAAAACAAAAAGTTAAACTCGCGGAAG
GTTTAGACGAAAATGCTGTGCTTAATCAAGAGGCTATCACGCGTGGCGTGAATTGCTTAGCCTTATTTGCTGAACGTTTA
CAAGGTTTTTCCGTTGAAAATGTCAATGTAGTTGGCACTTATACCTTACGCAGAGCCATCAATAATGATGAATTTTTACG
TCAAGCAGCCAAAGTTTTCCCCTATCCCATTAATATTATTAGTGGGCAAACGGAAGCTAAAACCATCTACGCAGGCGTAT
GCCATACTCAACCAGAAAAAGGTCGTAAGCTCGTTGTGGATATTGGTGGTGGTTCGACAGAAATGATCATCGGCGATGAT
TTCACGCCGCTTATGGCTGAAAGCCGCCACATGGGATGTGTGAGTTTTGCGACTCAATTTTTTACCGATGGCATCATTTC
CCCAGAAAACTTTCAACGCGCGCGCCAAAGTGCGATCAATAAAATCGAAGATTTAGGCTTTGAATATCGCAAATTAGGTT
GGCAATCTGTACTTGGTTCATCGGGAACGATTAAAACTGTTGCACAAGTCATTTCGACTAATCTCGATCCAAATGGAATC
ATTACAGCCGAGCGATTAAATGCTCTAATTAAACAAACACTACAAGCCAAGCATTTTACCGAGCTAAATATTAACGGTTT
AAACCAAGACCGCGTGGATGTTTTTGTACCCGGTTTAGCGATTTTAAGTGCAGTGTTTGACGTTTTTCGTATTCAACAAA
TGCGCTATTCTGACGGTGCATTGCGCGAAGGCGTCATTTATAGCCTAGAAAAAACTTCCAAGTTGCAGATATTCGAGCGA
GCACCGCTTGAAGGTTAA

Upstream 100 bases:

>100_bases
ACCTTACGTTATCGCCTAATGCCACAGCTTTATTTTCAATCCGTTTCCAGCACAAACCAAGTGTTTGATTTGCTTTATAA
ATTTGAATTTTAGGAATGTT

Downstream 100 bases:

>100_bases
GTGAGCAATTCAATATTGACCAAGCTCATCGCGTTGCGGATAGTGCTAATTTACTCAGTGCGCAATATTTATGGGAGAAA
AATTTAGGGCAAGCTAAATA

Product: exopolyphosphatase

Products: NA

Alternate protein names: Metaphosphatase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MNDAILEPKHRGNVREIAAIDLGSNSFHMIVARIVNGSIQVLLRLKQKVKLAEGLDENAVLNQEAITRGVNCLALFAERL
QGFSVENVNVVGTYTLRRAINNDEFLRQAAKVFPYPINIISGQTEAKTIYAGVCHTQPEKGRKLVVDIGGGSTEMIIGDD
FTPLMAESRHMGCVSFATQFFTDGIISPENFQRARQSAINKIEDLGFEYRKLGWQSVLGSSGTIKTVAQVISTNLDPNGI
ITAERLNALIKQTLQAKHFTELNINGLNQDRVDVFVPGLAILSAVFDVFRIQQMRYSDGALREGVIYSLEKTSKLQIFER
APLEG

Sequences:

>Translated_325_residues
MNDAILEPKHRGNVREIAAIDLGSNSFHMIVARIVNGSIQVLLRLKQKVKLAEGLDENAVLNQEAITRGVNCLALFAERL
QGFSVENVNVVGTYTLRRAINNDEFLRQAAKVFPYPINIISGQTEAKTIYAGVCHTQPEKGRKLVVDIGGGSTEMIIGDD
FTPLMAESRHMGCVSFATQFFTDGIISPENFQRARQSAINKIEDLGFEYRKLGWQSVLGSSGTIKTVAQVISTNLDPNGI
ITAERLNALIKQTLQAKHFTELNINGLNQDRVDVFVPGLAILSAVFDVFRIQQMRYSDGALREGVIYSLEKTSKLQIFER
APLEG
>Mature_325_residues
MNDAILEPKHRGNVREIAAIDLGSNSFHMIVARIVNGSIQVLLRLKQKVKLAEGLDENAVLNQEAITRGVNCLALFAERL
QGFSVENVNVVGTYTLRRAINNDEFLRQAAKVFPYPINIISGQTEAKTIYAGVCHTQPEKGRKLVVDIGGGSTEMIIGDD
FTPLMAESRHMGCVSFATQFFTDGIISPENFQRARQSAINKIEDLGFEYRKLGWQSVLGSSGTIKTVAQVISTNLDPNGI
ITAERLNALIKQTLQAKHFTELNINGLNQDRVDVFVPGLAILSAVFDVFRIQQMRYSDGALREGVIYSLEKTSKLQIFER
APLEG

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=305, Percent_Identity=56.3934426229508, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI48994966, Length=293, Percent_Identity=43.0034129692833, Blast_Score=235, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 35925; Mature: 35925

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDAILEPKHRGNVREIAAIDLGSNSFHMIVARIVNGSIQVLLRLKQKVKLAEGLDENAV
CCCCCCCCHHCCCCEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCE
LNQEAITRGVNCLALFAERLQGFSVENVNVVGTYTLRRAINNDEFLRQAAKVFPYPINII
ECHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCHHHHHHHHHHCCCCEEEE
SGQTEAKTIYAGVCHTQPEKGRKLVVDIGGGSTEMIIGDDFTPLMAESRHMGCVSFATQF
CCCCCCCEEEEEECCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHCCCCCHHHHHHHHH
FTDGIISPENFQRARQSAINKIEDLGFEYRKLGWQSVLGSSGTIKTVAQVISTNLDPNGI
HHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
ITAERLNALIKQTLQAKHFTELNINGLNQDRVDVFVPGLAILSAVFDVFRIQQMRYSDGA
EEHHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCC
LREGVIYSLEKTSKLQIFERAPLEG
HHCCEEEEECCCCCEEHEECCCCCC
>Mature Secondary Structure
MNDAILEPKHRGNVREIAAIDLGSNSFHMIVARIVNGSIQVLLRLKQKVKLAEGLDENAV
CCCCCCCCHHCCCCEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCE
LNQEAITRGVNCLALFAERLQGFSVENVNVVGTYTLRRAINNDEFLRQAAKVFPYPINII
ECHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCHHHHHHHHHHCCCCEEEE
SGQTEAKTIYAGVCHTQPEKGRKLVVDIGGGSTEMIIGDDFTPLMAESRHMGCVSFATQF
CCCCCCCEEEEEECCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHCCCCCHHHHHHHHH
FTDGIISPENFQRARQSAINKIEDLGFEYRKLGWQSVLGSSGTIKTVAQVISTNLDPNGI
HHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
ITAERLNALIKQTLQAKHFTELNINGLNQDRVDVFVPGLAILSAVFDVFRIQQMRYSDGA
EEHHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCC
LREGVIYSLEKTSKLQIFERAPLEG
HHCCEEEEECCCCCEEHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]