Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 148826494

GI number: 148826494

Start: 1536822

End: 1539170

Strand: Direct

Name: rnr [H]

Synonym: CGSHiEE_07735

Alternate gene names: 148826494

Gene position: 1536822-1539170 (Clockwise)

Preceding gene: 148826493

Following gene: 148826495

Centisome position: 84.77

GC content: 40.78

Gene sequence:

>2349_bases
ATGACAAAAAAACGTAAAAACTTAATCAACCAAGATCCTCATTACAAACGAGAATTGGAAAAATACGGCAATCCAATCCC
GAGCCGTGAATTTATTTTAAGCGTTATTCGAGACAATAATGCTCCGATGAATCGGGATGAAATTTTGACCGCACTTTCCA
TTCAAAATGAAGAGCAAATAGAAGCGATGCGTCGCCGATTACGCGCGATGGAAAATGATGGCCAATTAGTGTTCACCAAA
CGTAAACGCTATGCCTTACCAGAAAAATTAGATTTATTTAAAGGCACGGTAATTGGTCATCGCGAAGGTTTTGGTTTTTT
ACAGGTCGATGGCAAAAAGGATGATTTATTCATTCCGAACCATCAAATGCAAAGAGTCATGCATGGAGATTTTGTCTTAG
CGCAACCTGCTGGATTAGATCGTCGTGGTCGCCGTGAAGTGCGAATTGTGCGCGTATTAGAAAGCCGTAAAAAACAAATT
GTGGGTCGCTTTTTCTTAGAAAACGGTTTTAGCTATGTGGTGCCTGATGACAGCAGAATTGGCCGAGATATTCTCGTGCC
TAATGAACATCGTAATGGTGCTCGCATGGGACAAGTTGTCGTTGTCGAGTTGCAAGAACGCTCTGCCAGTTTTAACCAGC
CAATTGGCGTAATCACTGAAATTCTAGGCGATAATATGGCGAAAGGAATGGAAGTGGAAATCGCCTTGCGTAACCACGAT
ATTCCCCATAAGTTTCCAAGTGCGGTGGAAAAATACGTAAAAAAATTCACTGAAGAAGTCCCAGAAGAAGCCCAAAAAGG
TCGTGTAGATTTACGCAATTTGCCGCTTGTGACCATTGATGGCGAAGATGCTCGTGATTTTGACGATGCTGTTTATTGTG
AAAAACATGGCAAAGGCTGGAAACTTTGGGTCGCGGTTGCGGATGTCAGTTATTACGTACGTTTACGTTCCGCTTTGGAT
GTAGAAGCACATAATCGTGGTAACTCAGTCTATTTTCCGAACCGAGTTGTACCCATGCTACCTGAAATTTTATCGAATGG
CTTATGCTCTCTTAACCCTCAAGTAGATCGTTTGTGTATGGTGTGTGAGATGCAAATTTCAGCCAAAGGTAAGCTCACAG
ATTATCGCTTTTATGAAGCGGTGATGAATTCGCATGCCCGCCTCACTTATACCAAAGTAGCCAAAATGCTTGAAGGCGAT
GAGGAATTACGCACTCGTTATTCTACGCTTGTACCTCATTTAGAAGAACTTTATAAACTCTATCAAGCTTTGCTTGGCGC
ACGTCATCAACGTGGTGCGATCGATTTTGAAACCATTGAAACTAAGTTTATTTTCAATGCAATGGGGAGAATTGAGCGTA
TTGAACCCGTTGTTCGCAATGATGCCCACAAAATCATTGAGGAATGTATGATTCTTGCGAATATCGCAGCAGCTAATTTT
ATGGAAAAACATAAAGAGCCTGCGTTATATCGTATTCATGCCACCCCGAGCGAAGAAAAATTAACATCGTTCCGCACTTT
CTTAAGTGAGTTTGGTTTAACTTTAGAAGGTGGCTTAAAACCAACCACAAAAGACTATGCTGCTCTCTTAGAAAAAGTTA
AAGAACGGTCTGATCATGAACTTATTCAAACAATGTTGCTACGTTCATTAAGCCAAGCTGTCTATCACGCTGATAATATT
GGGCACTTTGGTTTGGCTTTGGAAGAATATGCTCACTTTACTTCGCCAATTCGCCGTTATCCAGACTTAACACTTCATCG
AGGTATCAAATATTTACTCGCTAAAGAACAAGGCGCAAAACGTAAAACAACTGATACAGGCGGTTATCATTACTCTTTTG
ATGAAATGGATTTACTTGGCAATCATTGTTCAATGACGGAACGCCGCGCCGATGACGCCACTCGTGAAGTGGCTGATTGG
CTGAAATGTGAATATATGCAAGATCATGTTGGCGAAGAATTTAGCGGTGTTATTTCATCTGTGACGGGATTTGGTTTATT
TGTACGCTTAGATGATTTATTCATCGATGGTTTAGTCCATATTTCCACCTTAGAAAACGATTATTACCAATTCGATGCAG
CAAAACAGCGTTTAATTGGCGAAAATAGTGGAATGCAATATCGCTTAGGCGATAAAGTCCGCATCAAAGTTGAAGCGGTA
CATTTAGAAAATAAAATGGTCGATTTTTCGCTGATGGGGAGTGAACGTAAACCTCGTCGAGCTGGAAAAACCGCGAAAGA
AAAAGCCAAGAAAGTCTTTAAAGAACTACCGTCTAAAGCCTCCAAAAAACGAAAAAGTGCGGTAAAAAAGAAAGACGTTT
CGAAGAAAACATCTAGAAAACAAAAATAA

Upstream 100 bases:

>100_bases
TAAAATATCCTTAAAATATACAGTGATAATTTTATCCCCGTCTTGCATTATCCCCCTTACAGTGTCAAACTCTCCGCACT
TTTTAAAACTGTAAAAAATA

Downstream 100 bases:

>100_bases
TTCAAATCCCATTGTGGGAATATATTAAAAATTCAAATAAGAAAAAGAGAAATTTATGTCAGAACAAATCTACGGCATTC
ATGCTGTTAATAGTATTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 782; Mature: 781

Protein sequence:

>782_residues
MTKKRKNLINQDPHYKRELEKYGNPIPSREFILSVIRDNNAPMNRDEILTALSIQNEEQIEAMRRRLRAMENDGQLVFTK
RKRYALPEKLDLFKGTVIGHREGFGFLQVDGKKDDLFIPNHQMQRVMHGDFVLAQPAGLDRRGRREVRIVRVLESRKKQI
VGRFFLENGFSYVVPDDSRIGRDILVPNEHRNGARMGQVVVVELQERSASFNQPIGVITEILGDNMAKGMEVEIALRNHD
IPHKFPSAVEKYVKKFTEEVPEEAQKGRVDLRNLPLVTIDGEDARDFDDAVYCEKHGKGWKLWVAVADVSYYVRLRSALD
VEAHNRGNSVYFPNRVVPMLPEILSNGLCSLNPQVDRLCMVCEMQISAKGKLTDYRFYEAVMNSHARLTYTKVAKMLEGD
EELRTRYSTLVPHLEELYKLYQALLGARHQRGAIDFETIETKFIFNAMGRIERIEPVVRNDAHKIIEECMILANIAAANF
MEKHKEPALYRIHATPSEEKLTSFRTFLSEFGLTLEGGLKPTTKDYAALLEKVKERSDHELIQTMLLRSLSQAVYHADNI
GHFGLALEEYAHFTSPIRRYPDLTLHRGIKYLLAKEQGAKRKTTDTGGYHYSFDEMDLLGNHCSMTERRADDATREVADW
LKCEYMQDHVGEEFSGVISSVTGFGLFVRLDDLFIDGLVHISTLENDYYQFDAAKQRLIGENSGMQYRLGDKVRIKVEAV
HLENKMVDFSLMGSERKPRRAGKTAKEKAKKVFKELPSKASKKRKSAVKKKDVSKKTSRKQK

Sequences:

>Translated_782_residues
MTKKRKNLINQDPHYKRELEKYGNPIPSREFILSVIRDNNAPMNRDEILTALSIQNEEQIEAMRRRLRAMENDGQLVFTK
RKRYALPEKLDLFKGTVIGHREGFGFLQVDGKKDDLFIPNHQMQRVMHGDFVLAQPAGLDRRGRREVRIVRVLESRKKQI
VGRFFLENGFSYVVPDDSRIGRDILVPNEHRNGARMGQVVVVELQERSASFNQPIGVITEILGDNMAKGMEVEIALRNHD
IPHKFPSAVEKYVKKFTEEVPEEAQKGRVDLRNLPLVTIDGEDARDFDDAVYCEKHGKGWKLWVAVADVSYYVRLRSALD
VEAHNRGNSVYFPNRVVPMLPEILSNGLCSLNPQVDRLCMVCEMQISAKGKLTDYRFYEAVMNSHARLTYTKVAKMLEGD
EELRTRYSTLVPHLEELYKLYQALLGARHQRGAIDFETIETKFIFNAMGRIERIEPVVRNDAHKIIEECMILANIAAANF
MEKHKEPALYRIHATPSEEKLTSFRTFLSEFGLTLEGGLKPTTKDYAALLEKVKERSDHELIQTMLLRSLSQAVYHADNI
GHFGLALEEYAHFTSPIRRYPDLTLHRGIKYLLAKEQGAKRKTTDTGGYHYSFDEMDLLGNHCSMTERRADDATREVADW
LKCEYMQDHVGEEFSGVISSVTGFGLFVRLDDLFIDGLVHISTLENDYYQFDAAKQRLIGENSGMQYRLGDKVRIKVEAV
HLENKMVDFSLMGSERKPRRAGKTAKEKAKKVFKELPSKASKKRKSAVKKKDVSKKTSRKQK
>Mature_781_residues
TKKRKNLINQDPHYKRELEKYGNPIPSREFILSVIRDNNAPMNRDEILTALSIQNEEQIEAMRRRLRAMENDGQLVFTKR
KRYALPEKLDLFKGTVIGHREGFGFLQVDGKKDDLFIPNHQMQRVMHGDFVLAQPAGLDRRGRREVRIVRVLESRKKQIV
GRFFLENGFSYVVPDDSRIGRDILVPNEHRNGARMGQVVVVELQERSASFNQPIGVITEILGDNMAKGMEVEIALRNHDI
PHKFPSAVEKYVKKFTEEVPEEAQKGRVDLRNLPLVTIDGEDARDFDDAVYCEKHGKGWKLWVAVADVSYYVRLRSALDV
EAHNRGNSVYFPNRVVPMLPEILSNGLCSLNPQVDRLCMVCEMQISAKGKLTDYRFYEAVMNSHARLTYTKVAKMLEGDE
ELRTRYSTLVPHLEELYKLYQALLGARHQRGAIDFETIETKFIFNAMGRIERIEPVVRNDAHKIIEECMILANIAAANFM
EKHKEPALYRIHATPSEEKLTSFRTFLSEFGLTLEGGLKPTTKDYAALLEKVKERSDHELIQTMLLRSLSQAVYHADNIG
HFGLALEEYAHFTSPIRRYPDLTLHRGIKYLLAKEQGAKRKTTDTGGYHYSFDEMDLLGNHCSMTERRADDATREVADWL
KCEYMQDHVGEEFSGVISSVTGFGLFVRLDDLFIDGLVHISTLENDYYQFDAAKQRLIGENSGMQYRLGDKVRIKVEAVH
LENKMVDFSLMGSERKPRRAGKTAKEKAKKVFKELPSKASKKRKSAVKKKDVSKKTSRKQK

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=442, Percent_Identity=31.2217194570136, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI190014625, Length=442, Percent_Identity=31.2217194570136, Blast_Score=180, Evalue=5e-45,
Organism=Homo sapiens, GI134288890, Length=506, Percent_Identity=28.2608695652174, Blast_Score=153, Evalue=8e-37,
Organism=Homo sapiens, GI19115966, Length=454, Percent_Identity=27.5330396475771, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI219521928, Length=454, Percent_Identity=27.5330396475771, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI156105695, Length=211, Percent_Identity=28.9099526066351, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI156105693, Length=211, Percent_Identity=28.9099526066351, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI87082383, Length=740, Percent_Identity=66.8918918918919, Blast_Score=1046, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=660, Percent_Identity=27.2727272727273, Blast_Score=175, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI212645896, Length=423, Percent_Identity=30.2600472813239, Blast_Score=175, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17553506, Length=464, Percent_Identity=28.8793103448276, Blast_Score=165, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324552, Length=565, Percent_Identity=24.7787610619469, Blast_Score=154, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24649634, Length=477, Percent_Identity=29.559748427673, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI19922976, Length=384, Percent_Identity=26.5625, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24654597, Length=384, Percent_Identity=26.5625, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24654592, Length=384, Percent_Identity=26.5625, Blast_Score=132, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 89850; Mature: 89719

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKRKNLINQDPHYKRELEKYGNPIPSREFILSVIRDNNAPMNRDEILTALSIQNEEQI
CCCHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHH
EAMRRRLRAMENDGQLVFTKRKRYALPEKLDLFKGTVIGHREGFGFLQVDGKKDDLFIPN
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCEEECCCCCEEEEECCCCCCEECCC
HQMQRVMHGDFVLAQPAGLDRRGRREVRIVRVLESRKKQIVGRFFLENGFSYVVPDDSRI
HHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
GRDILVPNEHRNGARMGQVVVVELQERSASFNQPIGVITEILGDNMAKGMEVEIALRNHD
CCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCHHHHHHHHCCHHCCCCEEEEEECCCC
IPHKFPSAVEKYVKKFTEEVPEEAQKGRVDLRNLPLVTIDGEDARDFDDAVYCEKHGKGW
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCCE
KLWVAVADVSYYVRLRSALDVEAHNRGNSVYFPNRVVPMLPEILSNGLCSLNPQVDRLCM
EEEEEEEHHHHHHHHHHHHCCHHCCCCCEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHH
VCEMQISAKGKLTDYRFYEAVMNSHARLTYTKVAKMLEGDEELRTRYSTLVPHLEELYKL
HHHHHCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
YQALLGARHQRGAIDFETIETKFIFNAMGRIERIEPVVRNDAHKIIEECMILANIAAANF
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
MEKHKEPALYRIHATPSEEKLTSFRTFLSEFGLTLEGGLKPTTKDYAALLEKVKERSDHE
HHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCHHH
LIQTMLLRSLSQAVYHADNIGHFGLALEEYAHFTSPIRRYPDLTLHRGIKYLLAKEQGAK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
RKTTDTGGYHYSFDEMDLLGNHCSMTERRADDATREVADWLKCEYMQDHVGEEFSGVISS
CCCCCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VTGFGLFVRLDDLFIDGLVHISTLENDYYQFDAAKQRLIGENSGMQYRLGDKVRIKVEAV
HHHCEEEEEEHHHHHCCHHEEEECCCHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEEE
HLENKMVDFSLMGSERKPRRAGKTAKEKAKKVFKELPSKASKKRKSAVKKKDVSKKTSRK
EECCCEEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QK
CC
>Mature Secondary Structure 
TKKRKNLINQDPHYKRELEKYGNPIPSREFILSVIRDNNAPMNRDEILTALSIQNEEQI
CCHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHH
EAMRRRLRAMENDGQLVFTKRKRYALPEKLDLFKGTVIGHREGFGFLQVDGKKDDLFIPN
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCEEECCCCCEEEEECCCCCCEECCC
HQMQRVMHGDFVLAQPAGLDRRGRREVRIVRVLESRKKQIVGRFFLENGFSYVVPDDSRI
HHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
GRDILVPNEHRNGARMGQVVVVELQERSASFNQPIGVITEILGDNMAKGMEVEIALRNHD
CCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCHHHHHHHHCCHHCCCCEEEEEECCCC
IPHKFPSAVEKYVKKFTEEVPEEAQKGRVDLRNLPLVTIDGEDARDFDDAVYCEKHGKGW
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCCE
KLWVAVADVSYYVRLRSALDVEAHNRGNSVYFPNRVVPMLPEILSNGLCSLNPQVDRLCM
EEEEEEEHHHHHHHHHHHHCCHHCCCCCEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHH
VCEMQISAKGKLTDYRFYEAVMNSHARLTYTKVAKMLEGDEELRTRYSTLVPHLEELYKL
HHHHHCCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
YQALLGARHQRGAIDFETIETKFIFNAMGRIERIEPVVRNDAHKIIEECMILANIAAANF
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
MEKHKEPALYRIHATPSEEKLTSFRTFLSEFGLTLEGGLKPTTKDYAALLEKVKERSDHE
HHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCHHH
LIQTMLLRSLSQAVYHADNIGHFGLALEEYAHFTSPIRRYPDLTLHRGIKYLLAKEQGAK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
RKTTDTGGYHYSFDEMDLLGNHCSMTERRADDATREVADWLKCEYMQDHVGEEFSGVISS
CCCCCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VTGFGLFVRLDDLFIDGLVHISTLENDYYQFDAAKQRLIGENSGMQYRLGDKVRIKVEAV
HHHCEEEEEEHHHHHCCHHEEEECCCHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEEE
HLENKMVDFSLMGSERKPRRAGKTAKEKAKKVFKELPSKASKKRKSAVKKKDVSKKTSRK
EECCCEEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]