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The map label for this gene is dat [H]

Identifier: 148826400

GI number: 148826400

Start: 1433787

End: 1435151

Strand: Direct

Name: dat [H]

Synonym: CGSHiEE_07215

Alternate gene names: 148826400

Gene position: 1433787-1435151 (Clockwise)

Preceding gene: 148826399

Following gene: 148826401

Centisome position: 79.08

GC content: 42.93

Gene sequence:

>1365_bases
ATGACAATGATTACCCCTGTACAAGCAATTCTTGCTTCAAACCAACATTTTTTAGATCGCCAAGATGTAATGGAATCCAA
CGTACGTAGTTATCCTCGTAAATTACCTTTTGCCTATGCAAAAGCACAAGGCTGTTGGGTTACTGATGTTGAAGGTAATG
AATACCTAGACTTTTTAGCAGGCGCAGGAACCCTTGCATTAGGACATAATCATCCTATATTAATGCAAGCCATTAAAGAC
GTATTAGATAGCGGATTGCCGTTACACACTTTAGATTTAACCACTCCACTTAAAGATGCGTTTAGTGAAGAATTATTGTC
ATTCTTCCCGAAAGATAAATATATCTTACAATTCACAGGCCCTTCTGGTGCAGATGCAAATGAAGCAGCCATCAAATTAG
CCAAAACTTACACAGGGCGTGGCAATATCATTGCTTTCTCTGGCGGTTTTCACGGTATGACCCAAGGGGCATTAGCCTTA
ACAGGTAATCTTGGTGCAAAAAATGCCGTTGAAAATTTAATGCCTGGCGTACAATTTATGCCATATCCACACGAATACCG
CTGCCCATTTGGCATTGGTGGAGAAGCGGGCGCGAAAGCAGTTGAACAATACTTTGAAAACTTCATCGAAGATGTAGAAA
GTGGCGTAGTAAAACCAGCTGCAGTAATTTTAGAAGCAATCCAAGGAGAAGGCGGCGTTGTTCCAGCACCAATAAGCTTC
TTACAAAAAGTACGTGAAGTAACCCAAAAACACGGCATTTTAATGATCGTCGATGAAGTGCAAGCTGGTTTCTGCCGTTC
TGGAAAAATGTTCGCCTTTGAACACGCAGGCATTGAGCCTGATATTATTGTGATGTCAAAAGCAGTTGGTGGCAGCTTAC
CATTAGCTGTATTAGCTATTCGTAAAGAATTTGATGCTTGGCAACCTGCAGGACATACAGGTACATTTCGTGGCAATCAA
TTAGCGATGGCGACAGGTTACGCTTCACTTAAAATTATGCGTGATGAAAACCTCGCACAAAATGCCCAAGAGCGTGGTGA
ATACTTAACCAACGCATTACGCGAATTAAGCAAAGAATATCCGTGCATCGGCAACGTACGTGGTCGTGGCTTAATGATGG
GGATCGATATTGTAGACGAACGCCAATCGAAAGATGCGACAGGGGCTTACCCGCGCGATTGTGAATTAGCGGCAGCAATC
CAAAAAGCTTGCTTCAAAAACAAACTCTTGCTCGAACGTGGCGGACGCGGTGGCAACGTGGTTCGCGTGCTTTGTGCGGT
AAACATCAACCAAAATGAATGCGAAGAATTTATCAAACGCTTCAAACAATCTGTTGTAGACGCATTGAAAGTGGTGCGTA
GTTAA

Upstream 100 bases:

>100_bases
TAGCGAGTCAAATGCCCTATGTGTCTGTTTTATAAACAGTAAATTTATCGCAAGGCACCCGACTTATTTTTTCACCTCTT
TTAGAAGGTTTTAATCAAAA

Downstream 100 bases:

>100_bases
TTAAAAGCGGTCTGATTTTGCAAATGTTTTGCGAATTTTGACCGCTTGTAAATTCAAAATGGTAGGGAAATCCCACCTTT
TTTCTACTCAACTGTATAAA

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTMITPVQAILASNQHFLDRQDVMESNVRSYPRKLPFAYAKAQGCWVTDVEGNEYLDFLAGAGTLALGHNHPILMQAIKD
VLDSGLPLHTLDLTTPLKDAFSEELLSFFPKDKYILQFTGPSGADANEAAIKLAKTYTGRGNIIAFSGGFHGMTQGALAL
TGNLGAKNAVENLMPGVQFMPYPHEYRCPFGIGGEAGAKAVEQYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISF
LQKVREVTQKHGILMIVDEVQAGFCRSGKMFAFEHAGIEPDIIVMSKAVGGSLPLAVLAIRKEFDAWQPAGHTGTFRGNQ
LAMATGYASLKIMRDENLAQNAQERGEYLTNALRELSKEYPCIGNVRGRGLMMGIDIVDERQSKDATGAYPRDCELAAAI
QKACFKNKLLLERGGRGGNVVRVLCAVNINQNECEEFIKRFKQSVVDALKVVRS

Sequences:

>Translated_454_residues
MTMITPVQAILASNQHFLDRQDVMESNVRSYPRKLPFAYAKAQGCWVTDVEGNEYLDFLAGAGTLALGHNHPILMQAIKD
VLDSGLPLHTLDLTTPLKDAFSEELLSFFPKDKYILQFTGPSGADANEAAIKLAKTYTGRGNIIAFSGGFHGMTQGALAL
TGNLGAKNAVENLMPGVQFMPYPHEYRCPFGIGGEAGAKAVEQYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISF
LQKVREVTQKHGILMIVDEVQAGFCRSGKMFAFEHAGIEPDIIVMSKAVGGSLPLAVLAIRKEFDAWQPAGHTGTFRGNQ
LAMATGYASLKIMRDENLAQNAQERGEYLTNALRELSKEYPCIGNVRGRGLMMGIDIVDERQSKDATGAYPRDCELAAAI
QKACFKNKLLLERGGRGGNVVRVLCAVNINQNECEEFIKRFKQSVVDALKVVRS
>Mature_453_residues
TMITPVQAILASNQHFLDRQDVMESNVRSYPRKLPFAYAKAQGCWVTDVEGNEYLDFLAGAGTLALGHNHPILMQAIKDV
LDSGLPLHTLDLTTPLKDAFSEELLSFFPKDKYILQFTGPSGADANEAAIKLAKTYTGRGNIIAFSGGFHGMTQGALALT
GNLGAKNAVENLMPGVQFMPYPHEYRCPFGIGGEAGAKAVEQYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISFL
QKVREVTQKHGILMIVDEVQAGFCRSGKMFAFEHAGIEPDIIVMSKAVGGSLPLAVLAIRKEFDAWQPAGHTGTFRGNQL
AMATGYASLKIMRDENLAQNAQERGEYLTNALRELSKEYPCIGNVRGRGLMMGIDIVDERQSKDATGAYPRDCELAAAIQ
KACFKNKLLLERGGRGGNVVRVLCAVNINQNECEEFIKRFKQSVVDALKVVRS

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=30.8235294117647, Blast_Score=189, Evalue=7e-48,
Organism=Homo sapiens, GI24119277, Length=452, Percent_Identity=27.4336283185841, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI4557809, Length=427, Percent_Identity=28.8056206088993, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI37574042, Length=397, Percent_Identity=29.9748110831234, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI226442705, Length=396, Percent_Identity=29.2929292929293, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI226442709, Length=329, Percent_Identity=31.6109422492401, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI284507298, Length=340, Percent_Identity=28.8235294117647, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI188536080, Length=387, Percent_Identity=28.6821705426357, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI38679950, Length=387, Percent_Identity=28.6821705426357, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI38679946, Length=387, Percent_Identity=28.6821705426357, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1787560, Length=439, Percent_Identity=34.1685649202733, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1789016, Length=440, Percent_Identity=31.8181818181818, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI145693181, Length=408, Percent_Identity=32.843137254902, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1788044, Length=424, Percent_Identity=30.4245283018868, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1789759, Length=417, Percent_Identity=27.8177458033573, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1786349, Length=348, Percent_Identity=28.735632183908, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786991, Length=345, Percent_Identity=28.4057971014493, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32564660, Length=428, Percent_Identity=32.0093457943925, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71992977, Length=440, Percent_Identity=30.2272727272727, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI25144271, Length=451, Percent_Identity=29.7117516629712, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI25144274, Length=443, Percent_Identity=27.765237020316, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=383, Percent_Identity=26.3707571801567, Blast_Score=95, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6323470, Length=375, Percent_Identity=32.5333333333333, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6324432, Length=347, Percent_Identity=31.9884726224784, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6321456, Length=454, Percent_Identity=27.3127753303965, Blast_Score=123, Evalue=8e-29,
Organism=Drosophila melanogaster, GI28574759, Length=425, Percent_Identity=30.8235294117647, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI161085790, Length=436, Percent_Identity=30.5045871559633, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI21357415, Length=425, Percent_Identity=28.4705882352941, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI21356575, Length=440, Percent_Identity=26.5909090909091, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281366494, Length=392, Percent_Identity=26.7857142857143, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24667139, Length=392, Percent_Identity=26.7857142857143, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24667143, Length=392, Percent_Identity=26.7857142857143, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 49378; Mature: 49247

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMITPVQAILASNQHFLDRQDVMESNVRSYPRKLPFAYAKAQGCWVTDVEGNEYLDFLA
CCCCHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHCCCHHCCCCCCEEEECCCCHHHHHHH
GAGTLALGHNHPILMQAIKDVLDSGLPLHTLDLTTPLKDAFSEELLSFFPKDKYILQFTG
CCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECC
PSGADANEAAIKLAKTYTGRGNIIAFSGGFHGMTQGALALTGNLGAKNAVENLMPGVQFM
CCCCCCHHHHHHHHHEECCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHCCCCEEC
PYPHEYRCPFGIGGEAGAKAVEQYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHH
LQKVREVTQKHGILMIVDEVQAGFCRSGKMFAFEHAGIEPDIIVMSKAVGGSLPLAVLAI
HHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHH
RKEFDAWQPAGHTGTFRGNQLAMATGYASLKIMRDENLAQNAQERGEYLTNALRELSKEY
HHHHCCCCCCCCCCCCCCCEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
PCIGNVRGRGLMMGIDIVDERQSKDATGAYPRDCELAAAIQKACFKNKLLLERGGRGGNV
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCE
VRVLCAVNINQNECEEFIKRFKQSVVDALKVVRS
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMITPVQAILASNQHFLDRQDVMESNVRSYPRKLPFAYAKAQGCWVTDVEGNEYLDFLA
CCCHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHCCCHHCCCCCCEEEECCCCHHHHHHH
GAGTLALGHNHPILMQAIKDVLDSGLPLHTLDLTTPLKDAFSEELLSFFPKDKYILQFTG
CCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECC
PSGADANEAAIKLAKTYTGRGNIIAFSGGFHGMTQGALALTGNLGAKNAVENLMPGVQFM
CCCCCCHHHHHHHHHEECCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHCCCCEEC
PYPHEYRCPFGIGGEAGAKAVEQYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHH
LQKVREVTQKHGILMIVDEVQAGFCRSGKMFAFEHAGIEPDIIVMSKAVGGSLPLAVLAI
HHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHH
RKEFDAWQPAGHTGTFRGNQLAMATGYASLKIMRDENLAQNAQERGEYLTNALRELSKEY
HHHHCCCCCCCCCCCCCCCEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
PCIGNVRGRGLMMGIDIVDERQSKDATGAYPRDCELAAAIQKACFKNKLLLERGGRGGNV
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCE
VRVLCAVNINQNECEEFIKRFKQSVVDALKVVRS
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]