Click here to switch to the map view.

The map label for this gene is murA [H]

Identifier: 148826305

GI number: 148826305

Start: 1317496

End: 1318770

Strand: Direct

Name: murA [H]

Synonym: CGSHiEE_06660

Alternate gene names: 148826305

Gene position: 1317496-1318770 (Clockwise)

Preceding gene: 148826304

Following gene: 148826306

Centisome position: 72.67

GC content: 39.69

Gene sequence:

>1275_bases
ATGGATAAATTTCGTGTTTATGGGCAATCTCGTTTAAGTGGAAGTGTGAATATTTCAGGCGCAAAAAACGCCGCACTTCC
AATTCTTTTTGCGGCTATTTTAGCTACAGAACCTGTTAAATTGACAAATGTTCCCGAACTTAAAGATATTGAAACAACTT
TAAATATTTTGCGTCAATTAGGCGTGATTGCAAATCGTGATGAAACTGGTGCAGTTTTATTAGATGCCTCTAATATCAAT
CATTTCACTGCACCTTATGAATTGGTTAAAACTATGCGTGCTTCAATTTGGGCATTGGCACCTTTAGTCGCTCGTTTCCA
TCAAGGTCAAGTCTCATTACCTGGAGGTTGTTCTATCGGAGCTAGACCTGTTGATCTCCACATTAGCGGTTTAGAAAAAT
TAGGTGCGGACATCGTTCTTGAAGAAGGATATGTAAAAGCACAAGTATCAGATCGTCTTGTTGGAACTCGAATTGTAATA
GAAAAAGTAAGTGTAGGCGCAACTTTATCTATTATGATGGCAGCAACCCTTGCGAAAGGTACGACAGTTATTGAAAACGC
CGCTCGTGAACCTGAAATTGTAGATACTGCAGATTTCCTTAATAAAATGGGTGCGAAAATAACAGGTGCAGGTTCTGATC
ACATTACGATTGAAGGTGTTGAACGTTTAACTGGTTGTGAGCACAGTGTTGTGCCAGATCGTATTGAAACGGGAACATTC
TTAATTGCTGCAGCCATTTCGGGCGGTCGTGTTGTTTGTCAAAATACTAAAGCGGATACTTTAGATGCCGTAATTGATAA
ACTCCGTGAAGCTGGTGCGCAAGTTGATGTAACTGAAAATAGCATTACTTTAGATATGCTTGGTAATCGCCCTAAAGCAG
TGAATATTCGTACTGCACCACATCCAGGGTTCCCAACTGATATGCAGGCTCAATTTACTTTATTAAATATGGTGGCAGAA
GGTACAAGCATTATCACTGAAACGATTTTTGAAAATCGTTTTATGCATATTCCTGAATTAATTCGTATGGGTGGTAAAGC
TGAAATTGAAGGGAATACAGCGGTATGTCACGGGGTTGAACAATTGTCTGGCACAGAGGTAATAGCGACAGATTTACGCG
CTTCAATCAGTTTAGTGCTTGCAGGTTGTATCGCAACGGGAGAAACCATTGTAGATCGTATTTATCATATCGATCGTGGT
TATGAACATATCGAAGATAAATTACGTGGTCTAGGTGCGAAAATTGAACGTTTTTCTGGAAGTGATGAAGCGTAA

Upstream 100 bases:

>100_bases
TTTAGCACTGGTGAAATTCACGCTCTAACCATCAAAACTTATACCGTAGAAAAATGGAAACGCGATCGTGCATTAAACCA
GTTTAATTAAGGATTTAAAA

Downstream 100 bases:

>100_bases
TTAGGTACGCTGCTTTTCTATTAGACATTACAAGTTTATTTATAATCTTAAATTTCTATTAATGCCTTTCTTTAGAAAGG
CATTTTTTTACTGAAATTTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDIETTLNILRQLGVIANRDETGAVLLDASNIN
HFTAPYELVKTMRASIWALAPLVARFHQGQVSLPGGCSIGARPVDLHISGLEKLGADIVLEEGYVKAQVSDRLVGTRIVI
EKVSVGATLSIMMAATLAKGTTVIENAAREPEIVDTADFLNKMGAKITGAGSDHITIEGVERLTGCEHSVVPDRIETGTF
LIAAAISGGRVVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAPHPGFPTDMQAQFTLLNMVAE
GTSIITETIFENRFMHIPELIRMGGKAEIEGNTAVCHGVEQLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRG
YEHIEDKLRGLGAKIERFSGSDEA

Sequences:

>Translated_424_residues
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDIETTLNILRQLGVIANRDETGAVLLDASNIN
HFTAPYELVKTMRASIWALAPLVARFHQGQVSLPGGCSIGARPVDLHISGLEKLGADIVLEEGYVKAQVSDRLVGTRIVI
EKVSVGATLSIMMAATLAKGTTVIENAAREPEIVDTADFLNKMGAKITGAGSDHITIEGVERLTGCEHSVVPDRIETGTF
LIAAAISGGRVVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAPHPGFPTDMQAQFTLLNMVAE
GTSIITETIFENRFMHIPELIRMGGKAEIEGNTAVCHGVEQLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRG
YEHIEDKLRGLGAKIERFSGSDEA
>Mature_424_residues
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDIETTLNILRQLGVIANRDETGAVLLDASNIN
HFTAPYELVKTMRASIWALAPLVARFHQGQVSLPGGCSIGARPVDLHISGLEKLGADIVLEEGYVKAQVSDRLVGTRIVI
EKVSVGATLSIMMAATLAKGTTVIENAAREPEIVDTADFLNKMGAKITGAGSDHITIEGVERLTGCEHSVVPDRIETGTF
LIAAAISGGRVVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAPHPGFPTDMQAQFTLLNMVAE
GTSIITETIFENRFMHIPELIRMGGKAEIEGNTAVCHGVEQLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRG
YEHIEDKLRGLGAKIERFSGSDEA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=72.1428571428571, Blast_Score=625, Evalue=1e-180,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45314; Mature: 45314

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDIETTLNILRQL
CCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHH
GVIANRDETGAVLLDASNINHFTAPYELVKTMRASIWALAPLVARFHQGQVSLPGGCSIG
CCEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
ARPVDLHISGLEKLGADIVLEEGYVKAQVSDRLVGTRIVIEKVSVGATLSIMMAATLAKG
CEEEEEEECCHHHCCCCEEEECCEEEEEHHCCHHHHEEEEEECCCCCHHHHHHHHHHHCC
TTVIENAAREPEIVDTADFLNKMGAKITGAGSDHITIEGVERLTGCEHSVVPDRIETGTF
CHHHHHCCCCCCCCCHHHHHHHHCCEEECCCCCCEEEECHHHHCCCCCCCCCCCCCCCCE
LIAAAISGGRVVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAP
EEEEECCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCEEEEEECC
HPGFPTDMQAQFTLLNMVAEGTSIITETIFENRFMHIPELIRMGGKAEIEGNTAVCHGVE
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCEEECCCHHHHHHHH
QLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRGYEHIEDKLRGLGAKIERFSG
HHCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCC
SDEA
CCCC
>Mature Secondary Structure
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDIETTLNILRQL
CCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHH
GVIANRDETGAVLLDASNINHFTAPYELVKTMRASIWALAPLVARFHQGQVSLPGGCSIG
CCEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
ARPVDLHISGLEKLGADIVLEEGYVKAQVSDRLVGTRIVIEKVSVGATLSIMMAATLAKG
CEEEEEEECCHHHCCCCEEEECCEEEEEHHCCHHHHEEEEEECCCCCHHHHHHHHHHHCC
TTVIENAAREPEIVDTADFLNKMGAKITGAGSDHITIEGVERLTGCEHSVVPDRIETGTF
CHHHHHCCCCCCCCCHHHHHHHHCCEEECCCCCCEEEECHHHHCCCCCCCCCCCCCCCCE
LIAAAISGGRVVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAP
EEEEECCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCEEEEEECC
HPGFPTDMQAQFTLLNMVAEGTSIITETIFENRFMHIPELIRMGGKAEIEGNTAVCHGVE
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCEEECCCHHHHHHHH
QLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRGYEHIEDKLRGLGAKIERFSG
HHCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCC
SDEA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA