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The map label for this gene is lptA [H]

Identifier: 148826239

GI number: 148826239

Start: 1248606

End: 1249124

Strand: Direct

Name: lptA [H]

Synonym: CGSHiEE_06300

Alternate gene names: 148826239

Gene position: 1248606-1249124 (Clockwise)

Preceding gene: 148826238

Following gene: 148826240

Centisome position: 68.87

GC content: 33.72

Gene sequence:

>519_bases
ATGAAGTTAGTAAGCAATAAAATTCTTTTTCTTGCAACGATGGTATTAGCATCAAGTTCAGCTTTTGCATTGAAAGCTGA
TGTTAATCAGCCGATAAATATTGTTTCGGATAATCAATCCTTAGATATGGAAAAAAGTGTAGTGACATTCACAGATAATG
TGGTAATTACACAGGGGTCTATTGTTATCAAAGCAAATAAAGTTGTCATCACTCGTCCTGCTGAAAAATCAGGGAAAAAA
GAAACTGTAGAAGCATTCGGCACGCCAGTCACATTCCATCAACAGTTAGATAATGGTAAGCCAGTGGATGGAAAAGCAAA
TAAAGTTCATTATGATCTTGGTAACGAATTTTTAACATTAACTAACAATGCCGAATTAAAGCAGCTTGATAGTAAAATTA
ATGGCAATGTTATTACCTATGATGTGAAAAAACAACAACTTAAAGCTAATGGTAATGGAAAATCACGGGTAACAACAGTT
CTTATTCCATCTCAATTACAACAAGCTAAAGGGAAGTAA

Upstream 100 bases:

>100_bases
GTTAAAATTAAGGGTAAAAATTTTAGTTCTACAGGATTAAAATTAGTCGGAAATTTACGCCAACAAGTGGCGACATTAAA
GGAACAGGTAAAAACATATT

Downstream 100 bases:

>100_bases
TCTATGTCAATTTTGACTGCAGAGAATTTAGCTAAAAGCTACAAAAGTCGTAAAGTTGTTTCGGATGTTAGTTTAACCGT
AAACTCTAATGAAATTGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MKLVSNKILFLATMVLASSSAFALKADVNQPINIVSDNQSLDMEKSVVTFTDNVVITQGSIVIKANKVVITRPAEKSGKK
ETVEAFGTPVTFHQQLDNGKPVDGKANKVHYDLGNEFLTLTNNAELKQLDSKINGNVITYDVKKQQLKANGNGKSRVTTV
LIPSQLQQAKGK

Sequences:

>Translated_172_residues
MKLVSNKILFLATMVLASSSAFALKADVNQPINIVSDNQSLDMEKSVVTFTDNVVITQGSIVIKANKVVITRPAEKSGKK
ETVEAFGTPVTFHQQLDNGKPVDGKANKVHYDLGNEFLTLTNNAELKQLDSKINGNVITYDVKKQQLKANGNGKSRVTTV
LIPSQLQQAKGK
>Mature_172_residues
MKLVSNKILFLATMVLASSSAFALKADVNQPINIVSDNQSLDMEKSVVTFTDNVVITQGSIVIKANKVVITRPAEKSGKK
ETVEAFGTPVTFHQQLDNGKPVDGKANKVHYDLGNEFLTLTNNAELKQLDSKINGNVITYDVKKQQLKANGNGKSRVTTV
LIPSQLQQAKGK

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=171, Percent_Identity=53.8011695906433, Blast_Score=180, Evalue=6e-47,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 18684; Mature: 18684

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVSNKILFLATMVLASSSAFALKADVNQPINIVSDNQSLDMEKSVVTFTDNVVITQGS
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCEEEEEECCEEEECCE
IVIKANKVVITRPAEKSGKKETVEAFGTPVTFHQQLDNGKPVDGKANKVHYDLGNEFLTL
EEEEECEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCCEEEEE
TNNAELKQLDSKINGNVITYDVKKQQLKANGNGKSRVTTVLIPSQLQQAKGK
ECCCHHHHHHHHCCCCEEEEECCCEEEECCCCCCCEEEEEEECHHHHHHCCC
>Mature Secondary Structure
MKLVSNKILFLATMVLASSSAFALKADVNQPINIVSDNQSLDMEKSVVTFTDNVVITQGS
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCEEEEEECCEEEECCE
IVIKANKVVITRPAEKSGKKETVEAFGTPVTFHQQLDNGKPVDGKANKVHYDLGNEFLTL
EEEEECEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCCEEEEE
TNNAELKQLDSKINGNVITYDVKKQQLKANGNGKSRVTTVLIPSQLQQAKGK
ECCCHHHHHHHHCCCCEEEEECCCEEEECCCCCCCEEEEEEECHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]