Click here to switch to the map view.

The map label for this gene is pabB [C]

Identifier: 148826219

GI number: 148826219

Start: 1226355

End: 1227341

Strand: Direct

Name: pabB [C]

Synonym: CGSHiEE_06190

Alternate gene names: 148826219

Gene position: 1226355-1227341 (Clockwise)

Preceding gene: 148826214

Following gene: 148826220

Centisome position: 67.64

GC content: 34.85

Gene sequence:

>987_bases
ATGGCACAAAGCACAATGCAACATTTTATTGAACAGGCTAATCATTATGGCAAACAACGCACGCCATTTTTCTTTCTTAT
TGATTTTGAAAAAGAAAAACCATTGATTTGTCCTCTCGAAAATTCTGCACAACAAGGCATTTATTTTGATATTTTAGGCA
AAAGAAATTGCACAATTTCTCCACGACCTCTCCCTCTTAATTTTACCAAACATCCAATGCCTTTCTCGCATTATCAACAA
GGTTTTGAACTTGTTCAAAGTGAATTACAAAAAGGTAATTCTTATCTATTAAATCTCACCTACCCCACTGAAATTTCAGG
TAAGCTGTCACTTGAACAAATTTTTCATCAAACCAATGCACCTTATAAATTGTGGTTACAAGATCAATTCGTTTGCTTTT
CGCCTGAATGTTTTGTCAATATTCATGACAACAATATTTTTACCTATCCCATGAAAGGGACAATTAATGCCTCTCTGCCC
GATGCAGAAAATCAGTTACTCACAAATGAAAAAGAACAACGCGAGCATTACACGATTGTTGATTTGATGCGTAATGATTT
ATCCATGGTGGCAAAAAACATTCAGGTGAAAAAATTTCGTTATATCGATCGTATCAAGACCCAGAAAGGCGAAATACTGC
AAACCAGTTCTGAAATTTACGGAAAATTGAATGAAAACTGGCAAAATCAAATTGGGGATATTTTAGAGAAACTGTTGCCT
GCTGGGTCTATTAGCGGCGCACCAAAAGAAAAAACCACACAAATTATTCAGCAAGCAGAAAAACAAAAACGCGGTTATTA
CACGGGAATTTTTGGCATATTTGATGGCAAAACACTACAAAGTGCGGTGGCAATTCGATTTATTTCTCAAGTAGATGAAA
AATTTTATTTTCATAGTGGAGGTGGAATTACCATTCATAGCAATGTGCAAGATGAATATGAAGAATTATTAGAAAAAGTC
TATTTACCGATTGAAGGTGCTGATTAA

Upstream 100 bases:

>100_bases
ATTAAATCCACCAAGTTAAAAGTAAAAGAATCGTGATTATTAATGATGAGTAATTTCATAACAGTTCGGTATTCGTTATA
ATCGGGTCATTTTACGCAAA

Downstream 100 bases:

>100_bases
TGTTCCCTCTATTTGAAACCCTTTGTATTGAAAACGGGAAAATTCAAAATATCGATTTACACCAAGTGCGATATGAACGT
AGTTTGCGTGAATATTATGG

Product: para-aminobenzoate synthase component I

Products: 4-amino-4-deoxychorismate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MAQSTMQHFIEQANHYGKQRTPFFFLIDFEKEKPLICPLENSAQQGIYFDILGKRNCTISPRPLPLNFTKHPMPFSHYQQ
GFELVQSELQKGNSYLLNLTYPTEISGKLSLEQIFHQTNAPYKLWLQDQFVCFSPECFVNIHDNNIFTYPMKGTINASLP
DAENQLLTNEKEQREHYTIVDLMRNDLSMVAKNIQVKKFRYIDRIKTQKGEILQTSSEIYGKLNENWQNQIGDILEKLLP
AGSISGAPKEKTTQIIQQAEKQKRGYYTGIFGIFDGKTLQSAVAIRFISQVDEKFYFHSGGGITIHSNVQDEYEELLEKV
YLPIEGAD

Sequences:

>Translated_328_residues
MAQSTMQHFIEQANHYGKQRTPFFFLIDFEKEKPLICPLENSAQQGIYFDILGKRNCTISPRPLPLNFTKHPMPFSHYQQ
GFELVQSELQKGNSYLLNLTYPTEISGKLSLEQIFHQTNAPYKLWLQDQFVCFSPECFVNIHDNNIFTYPMKGTINASLP
DAENQLLTNEKEQREHYTIVDLMRNDLSMVAKNIQVKKFRYIDRIKTQKGEILQTSSEIYGKLNENWQNQIGDILEKLLP
AGSISGAPKEKTTQIIQQAEKQKRGYYTGIFGIFDGKTLQSAVAIRFISQVDEKFYFHSGGGITIHSNVQDEYEELLEKV
YLPIEGAD
>Mature_327_residues
AQSTMQHFIEQANHYGKQRTPFFFLIDFEKEKPLICPLENSAQQGIYFDILGKRNCTISPRPLPLNFTKHPMPFSHYQQG
FELVQSELQKGNSYLLNLTYPTEISGKLSLEQIFHQTNAPYKLWLQDQFVCFSPECFVNIHDNNIFTYPMKGTINASLPD
AENQLLTNEKEQREHYTIVDLMRNDLSMVAKNIQVKKFRYIDRIKTQKGEILQTSSEIYGKLNENWQNQIGDILEKLLPA
GSISGAPKEKTTQIIQQAEKQKRGYYTGIFGIFDGKTLQSAVAIRFISQVDEKFYFHSGGGITIHSNVQDEYEELLEKVY
LPIEGAD

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To the C-terminal of para-aminobenzoate synthase component I [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=264, Percent_Identity=29.9242424242424, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787518, Length=230, Percent_Identity=28.695652173913, Blast_Score=72, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=220, Percent_Identity=28.6363636363636, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324361, Length=279, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR015890 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: 6.3.5.8

Molecular weight: Translated: 37825; Mature: 37694

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSTMQHFIEQANHYGKQRTPFFFLIDFEKEKPLICPLENSAQQGIYFDILGKRNCTIS
CCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCC
PRPLPLNFTKHPMPFSHYQQGFELVQSELQKGNSYLLNLTYPTEISGKLSLEQIFHQTNA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCC
PYKLWLQDQFVCFSPECFVNIHDNNIFTYPMKGTINASLPDAENQLLTNEKEQREHYTIV
CEEEEEECCEEEECCCEEEEEECCEEEEEECCCEEECCCCCCCHHHHCCCHHHHHHHHHH
DLMRNDLSMVAKNIQVKKFRYIDRIKTQKGEILQTSSEIYGKLNENWQNQIGDILEKLLP
HHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEECCHHHHHCCCCCHHHHHHHHHHHHCC
AGSISGAPKEKTTQIIQQAEKQKRGYYTGIFGIFDGKTLQSAVAIRFISQVDEKFYFHSG
CCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHEEEECC
GGITIHSNVQDEYEELLEKVYLPIEGAD
CCEEEECCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AQSTMQHFIEQANHYGKQRTPFFFLIDFEKEKPLICPLENSAQQGIYFDILGKRNCTIS
CHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCC
PRPLPLNFTKHPMPFSHYQQGFELVQSELQKGNSYLLNLTYPTEISGKLSLEQIFHQTNA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCC
PYKLWLQDQFVCFSPECFVNIHDNNIFTYPMKGTINASLPDAENQLLTNEKEQREHYTIV
CEEEEEECCEEEECCCEEEEEECCEEEEEECCCEEECCCCCCCHHHHCCCHHHHHHHHHH
DLMRNDLSMVAKNIQVKKFRYIDRIKTQKGEILQTSSEIYGKLNENWQNQIGDILEKLLP
HHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEECCHHHHHCCCCCHHHHHHHHHHHHCC
AGSISGAPKEKTTQIIQQAEKQKRGYYTGIFGIFDGKTLQSAVAIRFISQVDEKFYFHSG
CCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHEEEECC
GGITIHSNVQDEYEELLEKVYLPIEGAD
CCEEEECCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chorismate; L-glutamine

Specific reaction: chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate

General reaction: Lyases; Carbon-Carbon Lyases; Oxo-Acid-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]