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The map label for this gene is lldP [C]

Identifier: 148826174

GI number: 148826174

Start: 1178460

End: 1180058

Strand: Direct

Name: lldP [C]

Synonym: CGSHiEE_05935

Alternate gene names: 148826174

Gene position: 1178460-1180058 (Clockwise)

Preceding gene: 148826172

Following gene: 148826180

Centisome position: 65.0

GC content: 35.58

Gene sequence:

>1599_bases
ATGCTGTCTTTTGTTCTAAGTATTTTTCCTATCGTTTTACTGATTTATCTTATGGTAAAAAGAAACGCGCTACCTTCTTA
TGTTGCCTTACCTTGGATTGCGACATTAGTTATGGGCGTTCATCTTTTACACTTTAATACAGATATTGTCACTATTAGTG
CAAATGTTGTTTCTGCAATTATTGCGGTACAAACACCTATTACAGTAATTTTTGGTGCGATTCTCTTTAACCGTTTCTCT
GAAATTTCAGGCGCAACAAATATTATGCGAAAATGGCTAGGAAATATTAATCCAAATCCTGTTGCACAATTAATGATTAT
TGGTTGGGCATTTGCCTTTATGATCGAGGGGGCAAGTGGTTTTGGTACACCAGCGGCAATTGCTGCACCTATTTTAGTGG
GATTAGGTTTTCATCCATTAAAAGTGGCGATGTTGGCACTGATTATGAACTCAGTTCCCGTATCCTTTGGTGCGGTAGGT
ACACCAACTTGGTTTGGTTTTGGTGCTTTAAAATTATCAGAAAATATGATTTTAGAAATTGGGTCTATTACAGCATTTAT
CCACTCCATTGCTGCACTTCTTATCCCATTATTAGCACTTCGTATCTTAGTAAGTTGGGATGATATTCGTAAAAACATCG
TATTTATTTATATTAGCGTACTAGGTTGCGTAGTACCTTATTTCTTAATTGCTCAAGTCAATTACGAATTTCCATCACTC
GTTGGGGGGGCAATCGGCTTATTTATTTCCGTATGGGCTGCGAATCGCAATATTGGTTTAGCAAAAGTAACAAATACCCT
TGATAATAATGCGGTAAGTACGGGAGAAGTAGTTAAAGCATTATTCCCTACAGGTTTACTTATTGCATTTTTAATTGTGA
CTCGTATTCATCAATTACCATTCAAAGCAATGATGAATGACGCAACTATTTGGTTCTCAACCACATTAGGTTCGTTAGGA
TTATTTGAAATTAGCAAAGGTTTAATCTTTAGCTTAAAAAATATTTTTGGCTCAAATGTTTCATCAAGCTATAAACTTCT
TTACGTACCTGCATTGATTCCATTTGTCATTACAGTACTAATTGCGATTCCTGTCTTTAAAATTTCCAGTTCAAATGTTA
AACAGATTTTTGTATCAAGTTTACAACAATCTAAAAATCCATTTATTGCCTTAGTTGGTGCCTTAGTGATGGTAAACCTA
ATGTTAGTGGGTGGCGAACATTCTATGGTAAAAATTATAGGTAGAACTTTTGCTGAAATTTCTGGTAGTAACTGGACTAT
TTTCTCCTCTTTCTTAGGCGCGATTGGATCCTTTTTCTCAGGTTCAAATACCGTATCCAACCTAACATTTGGTAGTGTTC
AACTTTCTACCGCAGAAACAACAGGCATTTCTGTCGCACTTGTTCTTGCTTTACAATCTGTTGGTGGGGCAATGGGGAAT
ATGGTATGTATAAATAACATTGTAGCGGTAAGTTCAGTGTTAAATATTTCAAACCAAGAAGGCACAATTATTAAGAAAAC
CATTATACCTATGATCATTTACGGTATCATTGCCGCACTTGGCGCACTGTTCTTAGTACCTTTATTTTATAATCTATAA

Upstream 100 bases:

>100_bases
TTTATGAGATATTGATCACATTTTCTTAAAATAGGTATATGCTTTTGCATATAAATCCATAAAATAACCACATCTTTTAA
TCTAACTCTGAGGATATTTT

Downstream 100 bases:

>100_bases
AATTCACGCCAAAAATGACCGCACTTTTGCGGTCATTTCCTATTTTTCTCTTTTATATTTCTACCATCAAAAACGATTTT
CAACCCATTAAAGTGCGGTT

Product: putative L-lactate permease

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MLSFVLSIFPIVLLIYLMVKRNALPSYVALPWIATLVMGVHLLHFNTDIVTISANVVSAIIAVQTPITVIFGAILFNRFS
EISGATNIMRKWLGNINPNPVAQLMIIGWAFAFMIEGASGFGTPAAIAAPILVGLGFHPLKVAMLALIMNSVPVSFGAVG
TPTWFGFGALKLSENMILEIGSITAFIHSIAALLIPLLALRILVSWDDIRKNIVFIYISVLGCVVPYFLIAQVNYEFPSL
VGGAIGLFISVWAANRNIGLAKVTNTLDNNAVSTGEVVKALFPTGLLIAFLIVTRIHQLPFKAMMNDATIWFSTTLGSLG
LFEISKGLIFSLKNIFGSNVSSSYKLLYVPALIPFVITVLIAIPVFKISSSNVKQIFVSSLQQSKNPFIALVGALVMVNL
MLVGGEHSMVKIIGRTFAEISGSNWTIFSSFLGAIGSFFSGSNTVSNLTFGSVQLSTAETTGISVALVLALQSVGGAMGN
MVCINNIVAVSSVLNISNQEGTIIKKTIIPMIIYGIIAALGALFLVPLFYNL

Sequences:

>Translated_532_residues
MLSFVLSIFPIVLLIYLMVKRNALPSYVALPWIATLVMGVHLLHFNTDIVTISANVVSAIIAVQTPITVIFGAILFNRFS
EISGATNIMRKWLGNINPNPVAQLMIIGWAFAFMIEGASGFGTPAAIAAPILVGLGFHPLKVAMLALIMNSVPVSFGAVG
TPTWFGFGALKLSENMILEIGSITAFIHSIAALLIPLLALRILVSWDDIRKNIVFIYISVLGCVVPYFLIAQVNYEFPSL
VGGAIGLFISVWAANRNIGLAKVTNTLDNNAVSTGEVVKALFPTGLLIAFLIVTRIHQLPFKAMMNDATIWFSTTLGSLG
LFEISKGLIFSLKNIFGSNVSSSYKLLYVPALIPFVITVLIAIPVFKISSSNVKQIFVSSLQQSKNPFIALVGALVMVNL
MLVGGEHSMVKIIGRTFAEISGSNWTIFSSFLGAIGSFFSGSNTVSNLTFGSVQLSTAETTGISVALVLALQSVGGAMGN
MVCINNIVAVSSVLNISNQEGTIIKKTIIPMIIYGIIAALGALFLVPLFYNL
>Mature_532_residues
MLSFVLSIFPIVLLIYLMVKRNALPSYVALPWIATLVMGVHLLHFNTDIVTISANVVSAIIAVQTPITVIFGAILFNRFS
EISGATNIMRKWLGNINPNPVAQLMIIGWAFAFMIEGASGFGTPAAIAAPILVGLGFHPLKVAMLALIMNSVPVSFGAVG
TPTWFGFGALKLSENMILEIGSITAFIHSIAALLIPLLALRILVSWDDIRKNIVFIYISVLGCVVPYFLIAQVNYEFPSL
VGGAIGLFISVWAANRNIGLAKVTNTLDNNAVSTGEVVKALFPTGLLIAFLIVTRIHQLPFKAMMNDATIWFSTTLGSLG
LFEISKGLIFSLKNIFGSNVSSSYKLLYVPALIPFVITVLIAIPVFKISSSNVKQIFVSSLQQSKNPFIALVGALVMVNL
MLVGGEHSMVKIIGRTFAEISGSNWTIFSSFLGAIGSFFSGSNTVSNLTFGSVQLSTAETTGISVALVLALQSVGGAMGN
MVCINNIVAVSSVLNISNQEGTIIKKTIIPMIIYGIIAALGALFLVPLFYNL

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=543, Percent_Identity=25.5985267034991, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1789347, Length=262, Percent_Identity=26.7175572519084, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 56860; Mature: 56860

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFVLSIFPIVLLIYLMVKRNALPSYVALPWIATLVMGVHLLHFNTDIVTISANVVSAI
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCEEEEEHHHHHHH
IAVQTPITVIFGAILFNRFSEISGATNIMRKWLGNINPNPVAQLMIIGWAFAFMIEGASG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
FGTPAAIAAPILVGLGFHPLKVAMLALIMNSVPVSFGAVGTPTWFGFGALKLSENMILEI
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHEECCCHHEEH
GSITAFIHSIAALLIPLLALRILVSWDDIRKNIVFIYISVLGCVVPYFLIAQVNYEFPSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VGGAIGLFISVWAANRNIGLAKVTNTLDNNAVSTGEVVKALFPTGLLIAFLIVTRIHQLP
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
FKAMMNDATIWFSTTLGSLGLFEISKGLIFSLKNIFGSNVSSSYKLLYVPALIPFVITVL
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHH
IAIPVFKISSSNVKQIFVSSLQQSKNPFIALVGALVMVNLMLVGGEHSMVKIIGRTFAEI
HHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SGSNWTIFSSFLGAIGSFFSGSNTVSNLTFGSVQLSTAETTGISVALVLALQSVGGAMGN
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCEEEECCCCCCHHHHHHHHHHHHCCHHCC
MVCINNIVAVSSVLNISNQEGTIIKKTIIPMIIYGIIAALGALFLVPLFYNL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSFVLSIFPIVLLIYLMVKRNALPSYVALPWIATLVMGVHLLHFNTDIVTISANVVSAI
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCCEEEEEHHHHHHH
IAVQTPITVIFGAILFNRFSEISGATNIMRKWLGNINPNPVAQLMIIGWAFAFMIEGASG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
FGTPAAIAAPILVGLGFHPLKVAMLALIMNSVPVSFGAVGTPTWFGFGALKLSENMILEI
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHEECCCHHEEH
GSITAFIHSIAALLIPLLALRILVSWDDIRKNIVFIYISVLGCVVPYFLIAQVNYEFPSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VGGAIGLFISVWAANRNIGLAKVTNTLDNNAVSTGEVVKALFPTGLLIAFLIVTRIHQLP
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
FKAMMNDATIWFSTTLGSLGLFEISKGLIFSLKNIFGSNVSSSYKLLYVPALIPFVITVL
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHH
IAIPVFKISSSNVKQIFVSSLQQSKNPFIALVGALVMVNLMLVGGEHSMVKIIGRTFAEI
HHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SGSNWTIFSSFLGAIGSFFSGSNTVSNLTFGSVQLSTAETTGISVALVLALQSVGGAMGN
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCEEEECCCCCCHHHHHHHHHHHHCCHHCC
MVCINNIVAVSSVLNISNQEGTIIKKTIIPMIIYGIIAALGALFLVPLFYNL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]