Click here to switch to the map view.

The map label for this gene is sapB [H]

Identifier: 148826168

GI number: 148826168

Start: 1171183

End: 1172148

Strand: Direct

Name: sapB [H]

Synonym: CGSHiEE_05885

Alternate gene names: 148826168

Gene position: 1171183-1172148 (Clockwise)

Preceding gene: 148826167

Following gene: 148826169

Centisome position: 64.6

GC content: 35.2

Gene sequence:

>966_bases
ATGTTATGGTCGGTTCTTCGCCATATTCTGTGGGTGGCATTATTATTACTCGTATTATCGCTATTAGGCTTTGTCATTTT
ATTGCGCGATCCTCTTAATGCGAATCTTGTTACACAAAACATTTATATCGGCTATTTCCATTATTTAGGCACCTTGTTAC
AAGGTGATTTTGGCATTACCTATAACGGTGGAAAATCATTAATGAACCTTATTCTTACGGTTCTTCCTCCCACATTGGAA
CTTTGTTTCATTACATTGTTTTTGGCATTTATTTTTGGTTTGCCACTTGGCATTATAAGTGCGGTCAATTCTGAACAAGT
TTTTGCAAAAAGTTTACAAATCCTATCTTATGTAGGGCTATCTATTCCAATATTTTGGTTAGCCCCCATTTTACTGTATG
TTGCCGCGCTCTCACATTGGGAAATTGCCGCTATTGGACAATATAATTTGCTTTACGAAATTAAATCCATTACGGGATTT
CCTGTTATTGATATGTGGTTTCTGGAAGTACCTTATCGTACAAAAATCGTACAAAACATATTGCAACATTTAGCCTTACC
AACATTGGTATTGTGTATTTTGCCAACAATGGAAATTATCCGTATTATTCATCAACGAGCAGAATATATTTTGAATCAAA
ATTTTTCTAAAGTAGCGACAACACGGGGTTGGTCAAAATGGAAAATTCTCCATCAATATGTATTCCGTAATACTTTTCCC
CTGCTTGTTCCACAAGTACCACGTGTATTCACATTAGTATTAACGCAATGTATGTTGGTAGAAACGGCTTTAGGTTGGCC
TGGCATTGGTCGTTGGTTAATTAATGCCGTAAATGAACAAGATTACAACAGCATTGCCGCAGGTGTAATTGTTATTGGTG
TATGTATTATTTTGATTGATACATTCACTAAAATATTCACTTTTATACTCGATCCATTTAAAAAGAAAGGTTGGTATGCA
AGATAA

Upstream 100 bases:

>100_bases
AACGAATTTTAGTCGCAAATAGTCGTGTGAAAGGAGTAAAAATGACGCCTTTTGGTAGCTTAGATTTTTCCACCTTATAT
TTTATTCAGGAGAAACACTA

Downstream 100 bases:

>100_bases
AGAACCTGATGAATTCCGCGAAAGCACCTCAATCTTTCAAATTTGGTTACGCTTTCGTCAAAATACCATCGCACTTTTTA
GCTTTTATTTATTAATCGCA

Product: peptide ABC transporter permease protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLWSVLRHILWVALLLLVLSLLGFVILLRDPLNANLVTQNIYIGYFHYLGTLLQGDFGITYNGGKSLMNLILTVLPPTLE
LCFITLFLAFIFGLPLGIISAVNSEQVFAKSLQILSYVGLSIPIFWLAPILLYVAALSHWEIAAIGQYNLLYEIKSITGF
PVIDMWFLEVPYRTKIVQNILQHLALPTLVLCILPTMEIIRIIHQRAEYILNQNFSKVATTRGWSKWKILHQYVFRNTFP
LLVPQVPRVFTLVLTQCMLVETALGWPGIGRWLINAVNEQDYNSIAAGVIVIGVCIILIDTFTKIFTFILDPFKKKGWYA
R

Sequences:

>Translated_321_residues
MLWSVLRHILWVALLLLVLSLLGFVILLRDPLNANLVTQNIYIGYFHYLGTLLQGDFGITYNGGKSLMNLILTVLPPTLE
LCFITLFLAFIFGLPLGIISAVNSEQVFAKSLQILSYVGLSIPIFWLAPILLYVAALSHWEIAAIGQYNLLYEIKSITGF
PVIDMWFLEVPYRTKIVQNILQHLALPTLVLCILPTMEIIRIIHQRAEYILNQNFSKVATTRGWSKWKILHQYVFRNTFP
LLVPQVPRVFTLVLTQCMLVETALGWPGIGRWLINAVNEQDYNSIAAGVIVIGVCIILIDTFTKIFTFILDPFKKKGWYA
R
>Mature_321_residues
MLWSVLRHILWVALLLLVLSLLGFVILLRDPLNANLVTQNIYIGYFHYLGTLLQGDFGITYNGGKSLMNLILTVLPPTLE
LCFITLFLAFIFGLPLGIISAVNSEQVFAKSLQILSYVGLSIPIFWLAPILLYVAALSHWEIAAIGQYNLLYEIKSITGF
PVIDMWFLEVPYRTKIVQNILQHLALPTLVLCILPTMEIIRIIHQRAEYILNQNFSKVATTRGWSKWKILHQYVFRNTFP
LLVPQVPRVFTLVLTQCMLVETALGWPGIGRWLINAVNEQDYNSIAAGVIVIGVCIILIDTFTKIFTFILDPFKKKGWYA
R

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=288, Percent_Identity=34.375, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI1789965, Length=274, Percent_Identity=25.5474452554745, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787761, Length=342, Percent_Identity=26.6081871345029, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787497, Length=283, Percent_Identity=24.7349823321555, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787053, Length=275, Percent_Identity=24, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788504, Length=275, Percent_Identity=24.3636363636364, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36539; Mature: 36539

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWSVLRHILWVALLLLVLSLLGFVILLRDPLNANLVTQNIYIGYFHYLGTLLQGDFGIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCEE
YNGGKSLMNLILTVLPPTLELCFITLFLAFIFGLPLGIISAVNSEQVFAKSLQILSYVGL
ECCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
SIPIFWLAPILLYVAALSHWEIAAIGQYNLLYEIKSITGFPVIDMWFLEVPYRTKIVQNI
HHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHH
LQHLALPTLVLCILPTMEIIRIIHQRAEYILNQNFSKVATTRGWSKWKILHQYVFRNTFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCC
LLVPQVPRVFTLVLTQCMLVETALGWPGIGRWLINAVNEQDYNSIAAGVIVIGVCIILID
HHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TFTKIFTFILDPFKKKGWYAR
HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLWSVLRHILWVALLLLVLSLLGFVILLRDPLNANLVTQNIYIGYFHYLGTLLQGDFGIT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCEE
YNGGKSLMNLILTVLPPTLELCFITLFLAFIFGLPLGIISAVNSEQVFAKSLQILSYVGL
ECCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
SIPIFWLAPILLYVAALSHWEIAAIGQYNLLYEIKSITGFPVIDMWFLEVPYRTKIVQNI
HHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHH
LQHLALPTLVLCILPTMEIIRIIHQRAEYILNQNFSKVATTRGWSKWKILHQYVFRNTFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCC
LLVPQVPRVFTLVLTQCMLVETALGWPGIGRWLINAVNEQDYNSIAAGVIVIGVCIILID
HHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TFTKIFTFILDPFKKKGWYAR
HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]