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The map label for this gene is argS [H]

Identifier: 148826102

GI number: 148826102

Start: 1098643

End: 1100376

Strand: Direct

Name: argS [H]

Synonym: CGSHiEE_05515

Alternate gene names: 148826102

Gene position: 1098643-1100376 (Clockwise)

Preceding gene: 148826099

Following gene: 148826107

Centisome position: 60.6

GC content: 37.14

Gene sequence:

>1734_bases
GTGAATATTCAATCTATTCTATCCGATAAAATTAAACAAGCAATGGTTATTGCAGGTGCTGATCAATCTTGTGATGCGCT
TGTTCGTCAATCAGGCAAACCACAATTTGGCGATTATCAAGCCAACGGTATTATGGCTGCAGCAAAAAAATTAGGTTTAA
ATCCACGAGAATTTGCTCAAAAAGTTTTAGATAATCTTCAACTATCTGATATTGCAGAAAAATTAGAAATCGCAGGCCCA
GGTTTTATCAATATTTTCTTAAATCCAACTTGGCTAACAACTGAAATTTCAGCTGCACTTTCCCACAAAAATTTAGGTAT
TCAAGCTACCAATAAACAAACAGTTGTGATTGATTATTCCTCTCCAAACGTAGCAAAAGAAATGCACGTAGGTCATTTAC
GCTCTACGATAATCGGCGATGCTGTAGCTAGAACCCTTGAGTTTTTAGGTCACAATGTCATCCGCGCTAACCACGTAGGC
GACTGGGGAACGCAATTCGGAATGCTTATTGCTTATCTTGAAAAAATGCAAAACGAACACGCCAGTGAAATGGAATTACA
AGATCTTGAAGCCTTTTATCGCGAAGCCAAAAAACACTACGATGAAGATGAAATATTCGCTGAAAAAGCACGTAATTATG
TCGTGAAATTACAAGGTGGAGATGAATATTGTCGAGCGATGTGGAAACGTTTAGTCGATATTACTATGCAACAAAATCAG
CATAACTATGATCGCTTAAATGTGACTTTAACCGAAAAAGATGTAATGGGCGAAAGTCTTTATAATCCTATGTTACCGAG
CATTGTAGAAGATCTTAAAAAACAAGGCTTAGCTGTGGAAGATGATGGTGCATTAGTTGTTTATTTGGATGAATTCAAAA
ATAAAGAAGGAGACCCAATGGGCGTAATCGTTCAGAAAAAAGACGGCGGTTTCCTTTATACTACAACTGATATAGCTGCA
GCAAAATATCGTTATGAAACATTAAAAGCTAATCGCGCACTTGTTTTTTCAGATACTCGCCAAAGCCAACATATGCAACA
AGCTTGGCTAATTACTCGTAAAGCAGGTTATGTACCAGACAGTTTCTCGTTAGAGCATAAAAACTTTGGGATGATGCTTG
GTAAAGATGGCAAGCCATTTAAAACTCGTACTGGTGGCACAGTAAAATTAGCCGATCTATTAGATGAAGCCATCGAACGC
GCCACTGTATTAATTAATGAAAAAAATACCAATTTATCTAATGATGAAAAACAAGCTGTGATTGAGGCTATTGGTATTGG
ATCGGTAAAATATGCAGATCTATCCAAAAACCGCACCACGGATTACGTTTTTGATTGGGATAATATGTTAAGTTTCGAAG
GCAACACTGCGCCTTATATGCAATATGCTTACACCCGTATTCGTTCGATCTTTAATAAAACAGAGATAAATTCGACCGCA
CTTTTGGCTGCACCTTTAACTATTAAAGATGATAAAGAAAGAACGCTTGCAATCAAACTTCTCCAATTTGAAGAAGCCGT
GCAAACTGTCGGAAAAGAAGGCACACCACACGTGCTTTGTGCTTATTTATACGAACTTGCTGGCATATTCTCATCATTCT
ATGAACATTGCCCAATTTTAAATGCTGAAGATGAGGCCGTAAAATTAAGCCGTTTGAAATTGGCATTATTAACGGAAAAA
ACCTTAAAACAAGGTTTAGAGTTACTCGGTATTAAAACCGTAGAAAAAATGTAA

Upstream 100 bases:

>100_bases
ATTTTCCTGTAAATTTGTCATTTTGTCCCTTTGAGAAATATACAAAGAACGGTATCATAACCGATTATTTTTATTATTCA
ATTTGAACATAGGAAAAAAC

Downstream 100 bases:

>100_bases
TTTAGATAATTAAAATCCCTTTCTCACGAAAGGGATTTTTTATTCTGTAAATAAGCATAAAAAAAGTGCCCCAATGGGGC
ACTACTCGGAAAGCAAAATA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIQSILSDKIKQAMVIAGADQSCDALVRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQKVLDNLQLSDIAEKLEIAGP
GFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYSSPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNEHASEMELQDLEAFYREAKKHYDEDEIFAEKARNYVVKLQGGDEYCRAMWKRLVDITMQQNQ
HNYDRLNVTLTEKDVMGESLYNPMLPSIVEDLKKQGLAVEDDGALVVYLDEFKNKEGDPMGVIVQKKDGGFLYTTTDIAA
AKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPDSFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIER
ATVLINEKNTNLSNDEKQAVIEAIGIGSVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTEINSTA
LLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPILNAEDEAVKLSRLKLALLTEK
TLKQGLELLGIKTVEKM

Sequences:

>Translated_577_residues
MNIQSILSDKIKQAMVIAGADQSCDALVRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQKVLDNLQLSDIAEKLEIAGP
GFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYSSPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNEHASEMELQDLEAFYREAKKHYDEDEIFAEKARNYVVKLQGGDEYCRAMWKRLVDITMQQNQ
HNYDRLNVTLTEKDVMGESLYNPMLPSIVEDLKKQGLAVEDDGALVVYLDEFKNKEGDPMGVIVQKKDGGFLYTTTDIAA
AKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPDSFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIER
ATVLINEKNTNLSNDEKQAVIEAIGIGSVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTEINSTA
LLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPILNAEDEAVKLSRLKLALLTEK
TLKQGLELLGIKTVEKM
>Mature_577_residues
MNIQSILSDKIKQAMVIAGADQSCDALVRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQKVLDNLQLSDIAEKLEIAGP
GFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYSSPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNEHASEMELQDLEAFYREAKKHYDEDEIFAEKARNYVVKLQGGDEYCRAMWKRLVDITMQQNQ
HNYDRLNVTLTEKDVMGESLYNPMLPSIVEDLKKQGLAVEDDGALVVYLDEFKNKEGDPMGVIVQKKDGGFLYTTTDIAA
AKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPDSFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIER
ATVLINEKNTNLSNDEKQAVIEAIGIGSVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTEINSTA
LLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPILNAEDEAVKLSRLKLALLTEK
TLKQGLELLGIKTVEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=600, Percent_Identity=38.1666666666667, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI197100773, Length=595, Percent_Identity=28.7394957983193, Blast_Score=204, Evalue=2e-52,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=71.4038128249567, Blast_Score=884, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=595, Percent_Identity=40.1680672268908, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71985068, Length=563, Percent_Identity=40.1420959147425, Blast_Score=380, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17532153, Length=490, Percent_Identity=26.3265306122449, Blast_Score=147, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320548, Length=544, Percent_Identity=34.0073529411765, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6321883, Length=522, Percent_Identity=29.5019157088123, Blast_Score=227, Evalue=3e-60,
Organism=Drosophila melanogaster, GI18859963, Length=566, Percent_Identity=38.86925795053, Blast_Score=387, Evalue=1e-107,
Organism=Drosophila melanogaster, GI28571570, Length=480, Percent_Identity=30.2083333333333, Blast_Score=179, Evalue=5e-45,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64760; Mature: 64760

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQSILSDKIKQAMVIAGADQSCDALVRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQ
CCHHHHHHHHHHHEEEEECCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHH
KVLDNLQLSDIAEKLEIAGPGFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYS
HHHHCCCHHHHHHHHHHCCCCEEEEEECCEEEHHHHHHHHHHCCCCEEECCCEEEEEECC
SPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCC
ASEMELQDLEAFYREAKKHYDEDEIFAEKARNYVVKLQGGDEYCRAMWKRLVDITMQQNQ
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCC
HNYDRLNVTLTEKDVMGESLYNPMLPSIVEDLKKQGLAVEDDGALVVYLDEFKNKEGDPM
CCCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCEEEEEEHHHCCCCCCCE
GVIVQKKDGGFLYTTTDIAAAKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPD
EEEEEECCCCEEEEECHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCC
SFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIERATVLINEKNTNLSNDEKQAV
CCCCCCCCCCEEECCCCCCCEECCCCEEEHHHHHHHHHHHHEEEEECCCCCCCCHHHHHH
IEAIGIGSVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTEINSTA
HHHHCCCCEEEECCCCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEE
LLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPIL
EEEECEEECCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NAEDEAVKLSRLKLALLTEKTLKQGLELLGIKTVEKM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MNIQSILSDKIKQAMVIAGADQSCDALVRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQ
CCHHHHHHHHHHHEEEEECCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHH
KVLDNLQLSDIAEKLEIAGPGFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYS
HHHHCCCHHHHHHHHHHCCCCEEEEEECCEEEHHHHHHHHHHCCCCEEECCCEEEEEECC
SPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCC
ASEMELQDLEAFYREAKKHYDEDEIFAEKARNYVVKLQGGDEYCRAMWKRLVDITMQQNQ
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCC
HNYDRLNVTLTEKDVMGESLYNPMLPSIVEDLKKQGLAVEDDGALVVYLDEFKNKEGDPM
CCCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCEEEEEEHHHCCCCCCCE
GVIVQKKDGGFLYTTTDIAAAKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPD
EEEEEECCCCEEEEECHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCC
SFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIERATVLINEKNTNLSNDEKQAV
CCCCCCCCCCEEECCCCCCCEECCCCEEEHHHHHHHHHHHHEEEEECCCCCCCCHHHHHH
IEAIGIGSVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTEINSTA
HHHHCCCCEEEECCCCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEE
LLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPIL
EEEECEEECCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NAEDEAVKLSRLKLALLTEKTLKQGLELLGIKTVEKM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA