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The map label for this gene is sbcB [H]

Identifier: 148825915

GI number: 148825915

Start: 931206

End: 932627

Strand: Direct

Name: sbcB [H]

Synonym: CGSHiEE_04440

Alternate gene names: 148825915

Gene position: 931206-932627 (Clockwise)

Preceding gene: 148825914

Following gene: 148825922

Centisome position: 51.36

GC content: 35.16

Gene sequence:

>1422_bases
ATGGCAAAAGATTTCAGCTTTTTTATTTACGATTATGAAAGTTTTGGTGTAAATCCAGCAACAGATCGTCCTGCGCAATT
TGCGGGTATTCGTACAGATGCTGATTTTAATATCATTGGTAAACCAATAATGTTTTATTGTAAACAAACCAACGATTATT
TACCGGCTCCTGAAGCGGTAATGGTAACAGGAATTACACCACAAGAATGTAATGAAAAGGGGCTTTCAGAGCCTGAATTC
GCCGCAAATATCTTAGCAGAATTTTCCCAACCCAATACTTGTGTCATGGGTTATAACAATATTCGCTATGATGATGAAAT
GACGCGTTATACGTTTTATCGTAATTTCATTGATCCTTATGAATACAGCTGGAAAAATGGGAATTCACGCTGGGATTTGT
TAGATTTAGTACGAGCTTGTTATGCCCTGCGTCCAGAAGGAATTAATTGGGCTTATGACGATGATGGAATGCCAAGTTTC
CGCTTAGAAAAACTCACTAAAGCAAATGGTATTGAGCATGAAAATGCTCACGATGCCATGGCGGATGTATATGCAACTAT
TGCTATGGCGAAATTAATTAAAGAAAAACAACCTAAATTATTCCAATATTTCTTTGAAAATCGCGGTAAAAAAGAAATCG
AAAAATTAGTTGATACAGGAGCGATGACACCTTTAGTGCATGTTTCTGGAATGCTAGGGAATTATCGTGGAAATTGCACT
TGGGTTGCACCTTTATCTTGGCATCCGACAAATCAAAATGCATTAATTGTGTGTGATTTAACTGGCGATATCGATAATTT
ATTAGCCAAAAGTGCGGATGAATTACGGACAGATTTATATACCAAAAAATCTGAATTAGAAGAAAGAGGAGTTTCATCCG
TTCCGTTAAAACTTGTGCATATTAATAAATGTCCTATTTTAGCACCAGCTAAAACTTTGTTACCAGAAACAGCAAATCGA
TTGGGTATTGATCGACAATTATGCTTGGATAATCTTGCAAAATTACGAGCATCTTTTGATATTCGTGAAAAAGTGGCGGA
TATTTTTAATGAAGAACGTCAATTTGCATCGAATGATAATGTAGAAACTGAGTTATACAATGGCTTTTTTAGCAATGCTG
ATAAAAATAATATGGCTATTTTACGTAGTTTACCTGCAGAAAAATTATCTGAACATGGTTTAGCTTTTGAAGATAAACGT
ATCCTTGAATTATTGTTCCATTATCGTGCTCGCCACTTTTATAAAACCCTCACACGCGCTGAACAAATTAAATGGCAAAA
ATACCGACAGAATAAACTTGAAAAAAGTGCGGTAGAGTTTCAATCAGGTTTACAACGTTTAGCCGAGGAACATTCAGATA
ATTCTGAAAAACTATCTTTGCTACAACAAGTATATGAATATGGTATAAAATTACTAGGTTAG

Upstream 100 bases:

>100_bases
AAGAATTAGCAAGCTAAATTGGCTAGGCATTATTTTCAGTTTATCAGCTATTTTTTGCCTATATTATTTAGATAAAATTA
TTGCGTAAAAGAGAGTAGTC

Downstream 100 bases:

>100_bases
TCGATACGTTGTCACATTTTTTAGAAGAGCACGTTTTAATAAAAACGTGCTTTTTTTTGTTGTTTTTCAGGGAAGAAAAT
ATCCAAGAAATTCTCCAGAT

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MAKDFSFFIYDYESFGVNPATDRPAQFAGIRTDADFNIIGKPIMFYCKQTNDYLPAPEAVMVTGITPQECNEKGLSEPEF
AANILAEFSQPNTCVMGYNNIRYDDEMTRYTFYRNFIDPYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDDDGMPSF
RLEKLTKANGIEHENAHDAMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEIEKLVDTGAMTPLVHVSGMLGNYRGNCT
WVAPLSWHPTNQNALIVCDLTGDIDNLLAKSADELRTDLYTKKSELEERGVSSVPLKLVHINKCPILAPAKTLLPETANR
LGIDRQLCLDNLAKLRASFDIREKVADIFNEERQFASNDNVETELYNGFFSNADKNNMAILRSLPAEKLSEHGLAFEDKR
ILELLFHYRARHFYKTLTRAEQIKWQKYRQNKLEKSAVEFQSGLQRLAEEHSDNSEKLSLLQQVYEYGIKLLG

Sequences:

>Translated_473_residues
MAKDFSFFIYDYESFGVNPATDRPAQFAGIRTDADFNIIGKPIMFYCKQTNDYLPAPEAVMVTGITPQECNEKGLSEPEF
AANILAEFSQPNTCVMGYNNIRYDDEMTRYTFYRNFIDPYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDDDGMPSF
RLEKLTKANGIEHENAHDAMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEIEKLVDTGAMTPLVHVSGMLGNYRGNCT
WVAPLSWHPTNQNALIVCDLTGDIDNLLAKSADELRTDLYTKKSELEERGVSSVPLKLVHINKCPILAPAKTLLPETANR
LGIDRQLCLDNLAKLRASFDIREKVADIFNEERQFASNDNVETELYNGFFSNADKNNMAILRSLPAEKLSEHGLAFEDKR
ILELLFHYRARHFYKTLTRAEQIKWQKYRQNKLEKSAVEFQSGLQRLAEEHSDNSEKLSLLQQVYEYGIKLLG
>Mature_472_residues
AKDFSFFIYDYESFGVNPATDRPAQFAGIRTDADFNIIGKPIMFYCKQTNDYLPAPEAVMVTGITPQECNEKGLSEPEFA
ANILAEFSQPNTCVMGYNNIRYDDEMTRYTFYRNFIDPYEYSWKNGNSRWDLLDLVRACYALRPEGINWAYDDDGMPSFR
LEKLTKANGIEHENAHDAMADVYATIAMAKLIKEKQPKLFQYFFENRGKKEIEKLVDTGAMTPLVHVSGMLGNYRGNCTW
VAPLSWHPTNQNALIVCDLTGDIDNLLAKSADELRTDLYTKKSELEERGVSSVPLKLVHINKCPILAPAKTLLPETANRL
GIDRQLCLDNLAKLRASFDIREKVADIFNEERQFASNDNVETELYNGFFSNADKNNMAILRSLPAEKLSEHGLAFEDKRI
LELLFHYRARHFYKTLTRAEQIKWQKYRQNKLEKSAVEFQSGLQRLAEEHSDNSEKLSLLQQVYEYGIKLLG

Specific function: Also functions as a DNA deoxyribophosphodiesterase that release deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=468, Percent_Identity=56.6239316239316, Blast_Score=565, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54310; Mature: 54179

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDFSFFIYDYESFGVNPATDRPAQFAGIRTDADFNIIGKPIMFYCKQTNDYLPAPEAV
CCCCEEEEEEEHHHCCCCCCCCCCCHHCCEECCCCCCCCCCCCEEEECCCCCCCCCCCEE
MVTGITPQECNEKGLSEPEFAANILAEFSQPNTCVMGYNNIRYDDEMTRYTFYRNFIDPY
EEECCCHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCC
EYSWKNGNSRWDLLDLVRACYALRPEGINWAYDDDGMPSFRLEKLTKANGIEHENAHDAM
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHH
ADVYATIAMAKLIKEKQPKLFQYFFENRGKKEIEKLVDTGAMTPLVHVSGMLGNYRGNCT
HHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEE
WVAPLSWHPTNQNALIVCDLTGDIDNLLAKSADELRTDLYTKKSELEERGVSSVPLKLVH
EEECEEECCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
INKCPILAPAKTLLPETANRLGIDRQLCLDNLAKLRASFDIREKVADIFNEERQFASNDN
ECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VETELYNGFFSNADKNNMAILRSLPAEKLSEHGLAFEDKRILELLFHYRARHFYKTLTRA
CHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EQIKWQKYRQNKLEKSAVEFQSGLQRLAEEHSDNSEKLSLLQQVYEYGIKLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
AKDFSFFIYDYESFGVNPATDRPAQFAGIRTDADFNIIGKPIMFYCKQTNDYLPAPEAV
CCCEEEEEEEHHHCCCCCCCCCCCHHCCEECCCCCCCCCCCCEEEECCCCCCCCCCCEE
MVTGITPQECNEKGLSEPEFAANILAEFSQPNTCVMGYNNIRYDDEMTRYTFYRNFIDPY
EEECCCHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCC
EYSWKNGNSRWDLLDLVRACYALRPEGINWAYDDDGMPSFRLEKLTKANGIEHENAHDAM
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHH
ADVYATIAMAKLIKEKQPKLFQYFFENRGKKEIEKLVDTGAMTPLVHVSGMLGNYRGNCT
HHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEE
WVAPLSWHPTNQNALIVCDLTGDIDNLLAKSADELRTDLYTKKSELEERGVSSVPLKLVH
EEECEEECCCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
INKCPILAPAKTLLPETANRLGIDRQLCLDNLAKLRASFDIREKVADIFNEERQFASNDN
ECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VETELYNGFFSNADKNNMAILRSLPAEKLSEHGLAFEDKRILELLFHYRARHFYKTLTRA
CHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EQIKWQKYRQNKLEKSAVEFQSGLQRLAEEHSDNSEKLSLLQQVYEYGIKLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]