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The map label for this gene is neuA [H]

Identifier: 148825862

GI number: 148825862

Start: 853062

End: 853736

Strand: Direct

Name: neuA [H]

Synonym: CGSHiEE_04135

Alternate gene names: 148825862

Gene position: 853062-853736 (Clockwise)

Preceding gene: 148825860

Following gene: 148825863

Centisome position: 47.05

GC content: 38.96

Gene sequence:

>675_bases
ATGACAAGAATTGCAATTATTCCTGCGAGAGCAGGTTCTAAAGGAATTAAAGACAAAAATTTACAGCTTGTGGGTGGTGT
TTCTTTGGTGGGGCGTGCGATTTTGGCAGCGCAAGAATCGGGTATGTTTGATCAAATTGTCGTGACATCAGACGGCGAAA
ACATTTTAAAAGAAGCTACAAAATATGGTGCAAAAGCAGTGGCACGCCCTGAAAGTTTGGCACAAAGTGATACACGCACC
ATTGATGCTATTTTGCATTGCTTAGAAACTCTCAATATTTCACAAGGCACTGCCGCACTTTTGCAACCAACCAGCCCATT
GCGTAATGCTTTAGATATTCGTAATGCAATGGAAATTTTCCTTGGTGGCAAATATAAATCGGTGGTTTCCGCTTGCGAAT
GTGAACATCATCCTTATAAATCCTTCATTTTAGAAGGCACCGAAGTGCAGCCTATTCACGAATTAACCGATTTTGAAGCC
CCTCGCCAAAAATTACCGAAATCTTATCGTGCAAATGGCGCAATTTATATTAATGACATTGCAAGTCTCTTTGAAGAAAA
ACGCTTTTTTATTGCCCCAATGCGTTTTTATTTAATGCCAACTTATCGTTCCATTGATATTGATTCCACACTTGATTTGC
AATTAGCCGAAAGTTTAATTTCAAAAGAGTTTTAA

Upstream 100 bases:

>100_bases
TGTTAAACAAAAATGTGGTGCCATATTAAAGATTAGTTTTTGCTAAAACAAGGGAAAGATTCTAGAATGGTCAGCACTTT
TATCACAGAGGGTGAAAATA

Downstream 100 bases:

>100_bases
AAAAATTGGCCGCACTTTTGATCTGCACTCCAAAAGTTGGATTAAATAACCAACTAAGGTGCAGATTTTTTATGACCAAA
TACAATTTTTTTCAAGCAAC

Product: acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEATKYGAKAVARPESLAQSDTRT
IDAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIFLGGKYKSVVSACECEHHPYKSFILEGTEVQPIHELTDFEA
PRQKLPKSYRANGAIYINDIASLFEEKRFFIAPMRFYLMPTYRSIDIDSTLDLQLAESLISKEF

Sequences:

>Translated_224_residues
MTRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEATKYGAKAVARPESLAQSDTRT
IDAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIFLGGKYKSVVSACECEHHPYKSFILEGTEVQPIHELTDFEA
PRQKLPKSYRANGAIYINDIASLFEEKRFFIAPMRFYLMPTYRSIDIDSTLDLQLAESLISKEF
>Mature_223_residues
TRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEATKYGAKAVARPESLAQSDTRTI
DAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIFLGGKYKSVVSACECEHHPYKSFILEGTEVQPIHELTDFEAP
RQKLPKSYRANGAIYINDIASLFEEKRFFIAPMRFYLMPTYRSIDIDSTLDLQLAESLISKEF

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=225, Percent_Identity=29.3333333333333, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 24736; Mature: 24605

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEAT
CCEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
KYGAKAVARPESLAQSDTRTIDAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCHHHHHHHHHHHHHHHH
LGGKYKSVVSACECEHHPYKSFILEGTEVQPIHELTDFEAPRQKLPKSYRANGAIYINDI
HCCCHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHHCCCCHHHHCCHHHCCCCCEEHHHH
ASLFEEKRFFIAPMRFYLMPTYRSIDIDSTLDLQLAESLISKEF
HHHHHHCHHHEECHHHHEECCCCEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRIAIIPARAGSKGIKDKNLQLVGGVSLVGRAILAAQESGMFDQIVVTSDGENILKEAT
CEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
KYGAKAVARPESLAQSDTRTIDAILHCLETLNISQGTAALLQPTSPLRNALDIRNAMEIF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCHHHHHHHHHHHHHHHH
LGGKYKSVVSACECEHHPYKSFILEGTEVQPIHELTDFEAPRQKLPKSYRANGAIYINDI
HCCCHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHHCCCCHHHHCCHHHCCCCCEEHHHH
ASLFEEKRFFIAPMRFYLMPTYRSIDIDSTLDLQLAESLISKEF
HHHHHHCHHHEECHHHHEECCCCEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]