Click here to switch to the map view.

The map label for this gene is citC [H]

Identifier: 148825694

GI number: 148825694

Start: 639317

End: 640324

Strand: Direct

Name: citC [H]

Synonym: CGSHiEE_03185

Alternate gene names: 148825694

Gene position: 639317-640324 (Clockwise)

Preceding gene: 148825693

Following gene: 148825695

Centisome position: 35.26

GC content: 35.12

Gene sequence:

>1008_bases
ATGCAATTTGAGCGAATTTCTACTGAACAAAAAAAACTTTCTCTCATTCAGACATTTTTACATCAAAATGCGCTTAAATT
AGATGAACAAATCGAGTATTTTGTTGTTGGCTATAATGATAACGAACAAATCGTTGTCTGTGGCGGTTTAGCAGGCAATA
TCATAAAATGTGTTGCGATTGATGAGTCTTTGCGTGGTAGCGGTGTTGCCTTGCAATTAATTACTGAATTGGTTGATTTA
GCTTACACGCTAAAACGCCCACACCTTTTTATTTATACAAAACCCGAATATGCAACGTTGTTCAAATCTTGTGGTTTTTA
TATCATCTCTGATGCCAATCCTTATGTAGTATTGTTAGAAAATAGTGCTACGCGTTTACAAAAACAATGCTCATTATGGG
AGAAAATGCGTGTGGATGGTAATCGAATTGGCTCGATTGTAATGAACGCGAATCCATTTACCTTAGGTCATCGTTATTTA
ATTGAGCAAGCATTACAACAATGTGATCATCTGCATTTATTTATTGTCGGTGAAGACGCATCGCAATTTTCTTACACTGA
ACGATTTGAAATGATTAAACAAGGTATTTTCGATTTATCCAATATCACTCTTCATTCTGGCTCTGACTATATTATTTCTC
GTGCAACATTTCCAAATTATTTCCTAAAAGATCAATTAATTACAGATGAAAGTTATTTTGAGATTGATCTGAAGTTATTC
CGTTTACATATTGCTCAAGCTTTGGGAATAACACATCGCTTTGTTGGTACTGAGCTAAATTGTCCCGTCACTGCCGAATA
TAATCGCCAAATGCATTATTGGTTAATGGATGCCGAAATGAATGCACCAAAAATAAATGTTATCGAGATACCTAGAAAAA
CAGCAAGCAACCACATTATTTCTGCTTCTACAGTACGAAAGCATTTGGCTGAAAAAAATTGGACTCAACTCGCAGAGCTT
GTGCCTATGACTACGTTAAATTATTTACAAAAGTGCGGTCGTTTTTAA

Upstream 100 bases:

>100_bases
ATATGAGCTTATCTTGTATCGTAATTTGCTCATCGCTTATAATAGCTCTACACTACTAACTTGGTAGTGATGTTATGTTT
TCTTCTTTTTTGGAGAGTCG

Downstream 100 bases:

>100_bases
ATACATTTTTATTCATCAATATACGGAAGGAAAATCTATGAAAATAACAAAAGTAGCCGTTGCAGGGACACTGGAATCCA
GTGATGTTCAAGTACGGGTT

Product: citrate lyase ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MQFERISTEQKKLSLIQTFLHQNALKLDEQIEYFVVGYNDNEQIVVCGGLAGNIIKCVAIDESLRGSGVALQLITELVDL
AYTLKRPHLFIYTKPEYATLFKSCGFYIISDANPYVVLLENSATRLQKQCSLWEKMRVDGNRIGSIVMNANPFTLGHRYL
IEQALQQCDHLHLFIVGEDASQFSYTERFEMIKQGIFDLSNITLHSGSDYIISRATFPNYFLKDQLITDESYFEIDLKLF
RLHIAQALGITHRFVGTELNCPVTAEYNRQMHYWLMDAEMNAPKINVIEIPRKTASNHIISASTVRKHLAEKNWTQLAEL
VPMTTLNYLQKCGRF

Sequences:

>Translated_335_residues
MQFERISTEQKKLSLIQTFLHQNALKLDEQIEYFVVGYNDNEQIVVCGGLAGNIIKCVAIDESLRGSGVALQLITELVDL
AYTLKRPHLFIYTKPEYATLFKSCGFYIISDANPYVVLLENSATRLQKQCSLWEKMRVDGNRIGSIVMNANPFTLGHRYL
IEQALQQCDHLHLFIVGEDASQFSYTERFEMIKQGIFDLSNITLHSGSDYIISRATFPNYFLKDQLITDESYFEIDLKLF
RLHIAQALGITHRFVGTELNCPVTAEYNRQMHYWLMDAEMNAPKINVIEIPRKTASNHIISASTVRKHLAEKNWTQLAEL
VPMTTLNYLQKCGRF
>Mature_335_residues
MQFERISTEQKKLSLIQTFLHQNALKLDEQIEYFVVGYNDNEQIVVCGGLAGNIIKCVAIDESLRGSGVALQLITELVDL
AYTLKRPHLFIYTKPEYATLFKSCGFYIISDANPYVVLLENSATRLQKQCSLWEKMRVDGNRIGSIVMNANPFTLGHRYL
IEQALQQCDHLHLFIVGEDASQFSYTERFEMIKQGIFDLSNITLHSGSDYIISRATFPNYFLKDQLITDESYFEIDLKLF
RLHIAQALGITHRFVGTELNCPVTAEYNRQMHYWLMDAEMNAPKINVIEIPRKTASNHIISASTVRKHLAEKNWTQLAEL
VPMTTLNYLQKCGRF

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=329, Percent_Identity=53.4954407294833, Blast_Score=360, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 38492; Mature: 38492

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFERISTEQKKLSLIQTFLHQNALKLDEQIEYFVVGYNDNEQIVVCGGLAGNIIKCVAI
CCCHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCEEEEEEE
DESLRGSGVALQLITELVDLAYTLKRPHLFIYTKPEYATLFKSCGFYIISDANPYVVLLE
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCEEEEECCCCEEEEEC
NSATRLQKQCSLWEKMRVDGNRIGSIVMNANPFTLGHRYLIEQALQQCDHLHLFIVGEDA
CCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCC
SQFSYTERFEMIKQGIFDLSNITLHSGSDYIISRATFPNYFLKDQLITDESYFEIDLKLF
HHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCHHHHCEEECCCCEEEHHHHHH
RLHIAQALGITHRFVGTELNCPVTAEYNRQMHYWLMDAEMNAPKINVIEIPRKTASNHII
HHHHHHHHCHHHHHCCCCCCCCEEECCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEE
SASTVRKHLAEKNWTQLAELVPMTTLNYLQKCGRF
EHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQFERISTEQKKLSLIQTFLHQNALKLDEQIEYFVVGYNDNEQIVVCGGLAGNIIKCVAI
CCCHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCEEEEEEE
DESLRGSGVALQLITELVDLAYTLKRPHLFIYTKPEYATLFKSCGFYIISDANPYVVLLE
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCEEEEECCCCEEEEEC
NSATRLQKQCSLWEKMRVDGNRIGSIVMNANPFTLGHRYLIEQALQQCDHLHLFIVGEDA
CCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCC
SQFSYTERFEMIKQGIFDLSNITLHSGSDYIISRATFPNYFLKDQLITDESYFEIDLKLF
HHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCHHHHCEEECCCCEEEHHHHHH
RLHIAQALGITHRFVGTELNCPVTAEYNRQMHYWLMDAEMNAPKINVIEIPRKTASNHII
HHHHHHHHCHHHHHCCCCCCCCEEECCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEE
SASTVRKHLAEKNWTQLAELVPMTTLNYLQKCGRF
EHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]